Insulin Detemir

Levemir

Levemir is an FDA-approved long-acting type of insulin that is used to manage type 1 and type 2 diabetes. It contains insulin detemir and is used as an injection under the skin (subcutaneously). It lasts up to 24 hours, depending on the dose. Your doctor or nurse will show you how to inject it safely and effectively. For best results, use this medication consistently. Do not use Levemir if you are allergic to it, its ingredients, or any insulin. For more guidance on usage, dosage, storage, disposal, and more, consult your doctor and discuss the potential risks and benefits of the medication. 

Product Overview

Levemir is a long-acting insulin-containing insulin detemir approved by the FDA for managing type 1 and type 2 diabetes. It is administered via subcutaneous injection and lasts up to 24 hours, depending on the dose. Levemir helps maintain a steady level of insulin in the body to control blood glucose levels and prevent complications of diabetes.

Levemir is available as a 100IU/ml Flexpen and can be used alone or with other diabetes medications. It should be used consistently and as directed by a healthcare professional. Common side effects include low blood sugar levels, injection site reactions, and weight gain. Levemir is contraindicated in individuals with allergies to insulin detemir or any insulin, and caution should be exercised in those with kidney, liver, or heart issues.

To take Levemir, follow your doctor’s instructions closely. It is crucial not to miss doses, but if you do, take it as soon as possible unless it is almost time for your next dose. Do not double dose. Store Levemir in a safe place, away from children, at 2 °C to 8°C or below 30°C. If you suspect an overdose or experience severe allergic reactions, seek medical assistance immediately. Levemir may interact with other medications, so inform your healthcare provider about all medications you are taking.

What is Levemir Used For?

• It regulates blood sugar levels in individuals with type 1 diabetes. 
• It is used to treat type 2 diabetes in adults, adolescents and children above the age of 2 years. 

[Note: Do not take Escitalopram without consulting your doctor. They will determine whether you need this medication based on your conditions.]

What Are the Forms & Strengths of Levemir?

• Form: Prefilled FlexTouch pen
• Strength: 3 ml
• Form: Vial 
• Strength: 10 ml 

What Is the Recommended Dosage of Levemir?

Before you buy Levemir online, you must consult a medical professional for appropriate dosage recommendations. It is important as the dosage of insulin-based medication depends on various factors, including the type and severity of the condition, age, weight, or any medical problem you may have. By analyzing these factors, your doctor will prescribe a starting dose and gradually adjust the dosage on the basis of your response to the treatment. The following recommendations are only the average doses of Levemir, so if you have been prescribed a different dosing schedule, follow it exactly.

Type 1 Diabetes 

• Initial Dose: one-third to one-half of the total daily insulin dose. 
• Recommended Dose: 0.2 to 0.4 units of insulin per kilogram of body weight.

Type 2 Diabetes 

• Recommended Initial Dose: 0.1 units/kg to 0.2 units/kg or ten units. 
• To be administered once daily or twice daily. 

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use Levemir?

• You should carefully read the patient information leaflet that comes with your prescription and follow the instructions given by your doctor. 
• Before you use insulin for the first time, your doctor will show you how to use it effectively. 
• If you have any queries regarding the medication’s usage, dosage, potential risks or benefits, ask your doctor or healthcare provider before using the medication. 
• Check the insulin for any change in appearance. Do not use it if it is discolored, cloudy, or has particles. 
• Before injecting the dose properly, wash your hands and clean the injection site with rubbing alcohol, soap, and water. 
• As your doctor directs, inject this insulin subcutaneously, typically once or twice a day.  
• Rotate the injection spot each time you inject the medication to prevent lumps and pits from forming under your skin. 
• The best spots to inject the medication are the abdomen, upper arm, and front thigh.  
• Do not inject Levemir into a vein or muscle. 
• Do not inject into skin that is torn, damaged, red, swollen, itchy, or has stretch marks. 
• Do not inject cold insulin, as it may be painful. 
• Do not change your type, brand, or dosage of insulin without consulting your doctor.
• Do not dilute or mix Levemir with other insulin. 
• Do not use this medication in an infusion pump. 
• Do not share your syringe or pen device with anyone, as it may cause infection to spread from one person to another. 
• The insulin dosage is based on your medical condition, age, needs, and how your body responds to treatment. 
• You must check your blood sugar levels regularly and share the report with your doctor to help them determine the correct dose for you.
• Let your doctor know if your condition does not improve or worsen.   

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Levemir Work?

Levemir works by allowing cells throughout the body to uptake glucose so that your body can use it for energy. It is a long-acting insulin that starts working within 2 hours after injection and continues to manage your blood sugar for several hours in the day. This steady and prolonged effect helps maintain stable blood sugar levels and prevent complications associated with diabetes, such as eye damage, kidney damage, loss of limbs, and problems related to the kidney, liver, and heart. 

Important Safety Information for Using Levemir

What Are the Side Effects of Levemir?

Common Side Effects: Like all medication, insulin detemir also has some side effects. These effects are temporary and usually disappear within a few days or weeks. They do not require any special medical attention and are generally experienced by every individual at the initial stage of the treatment. However, if these side effects intensify or stay for an extended period, consult your doctor. Some of the common side effects of Levemir may include:

• Hypoglycemia: Taking too much insulin or more than the prescribed dose can make your blood sugar levels drop down quickly. This can cause hypoglycemia if you don’t eat in time.
• Injection Site Reaction: Insulin administration may lead to skin redness, swelling, itching, or pain around the administration area. This happens when you inject the dose in the same area. To avoid this side effect, change the injection site frequently. 
• Weight Gain: Levemir is an insulin-based medication that helps the body store fat for energy production. When you inject excessive insulin, it stores the insulin in the body (more calories), leading to weight gain.
• Dizziness: Reduced blood sugar levels may affect your brain’s functioning, leading to lightheadedness or dizziness. 
• Blurred Vision: Uncontrolled blood sugar levels can affect your eyesight. This imbalance can cause blurred vision in certain patients. 
• Edema: Patients using this medication may notice swelling in the hands and feet. This happens when the body retains more fluid than usual.  

Serious Side Effects: Levemir contains insulin detemir as its active ingredient, which can react with certain conditions and cause severe side effects. If you have any medical condition or suspect any unwanted reactions or problems after using the Levemir flextouch insulin detemir injection, do not overlook the situation. Instead, take prompt action and reach out to a medical professional. Some of the serious side effects of Levemir may include:

• Severe Hypoglycemia: Low blood sugar levels may not necessarily lead to life-threatening situations if it is mild. However, severe hypoglycemia, if not treated in time, can cause adverse reactions like confusion, seizures, or loss of consciousness. 
• Severe Allergic Reaction: Sometimes, patients with existing allergies or those who have hypersensitivity to some of the products of Levemir may experience allergic reactions. If overlooked, this side effect can become a medical emergency. If you suspect symptoms like rash, itching, difficulty breathing, rapid heartbeats, or swelling on the face, lips, or throat, consult a healthcare practitioner.
• Hypokalemia: Levemir can cause low potassium levels, causing muscle cramps, irregular heart rhythms, or weakness. Therefore, always monitor your potassium levels during your treatment with this medication.

[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Levemir?

While Levemir is a well-tolerated medication, it can cause potential risks in several patients. So, if you decide to buy Levemir insulin, be aware of the following warnings:

• Do not share your syringes, needles, or other injectable products with other people, even if the needle is changed, as it may cause infection to spread from one person to another.
• Do not take Thiazolidinediones alongside any insulin, including Levemir, as it may cause heart failure. Patients using Levemir and TZDs should be monitored for any signs of heart failure. 
• Insulin-based medications like Levemir sometimes cause hypoglycemia in certain patients. It is one of the common side effects of insulin detemir that can cause seizures or death in rare cases. So, if you are experiencing weakness, dizziness, sweating, hunger, or nausea, seek immediate medical assistance. 
• Be cautious while mixing your medication, as accidental insulin changes may drop your blood sugar levels drastically. To avoid potential risks, check the insulin label before injecting the dose.
• Many patients have reported severe cases of anaphylaxis, an allergic reaction. If you suspect any hypersensitivity reactions, discontinue the use and talk to your doctor. 
• Levemir may also cause conditions like hypokalemia, which, if left untreated, can lead to ventricular arrhythmia, respiratory paralysis, and, in severe cases, death. So, if you are considering treatment with this medication, check your potassium levels frequently.

What Are the Precautions for Insulin Detemir (Levemir)?

Like all medications, Levemir can cause adverse reactions if not taken properly. Therefore, always consult your physician when considering treatment with this medication. They will suggest some important safety information before administering your dose. However, some of the basic preventive measures are as follows:

• Do not take Levemir if you are allergic to insulin detemir, ingredients, or insulins.
• Do not take this medication if you have severe low blood sugar. 
• Before taking this drug, let your doctor know if you have a disease related to the kidney, heart or liver.
• If you think you are pregnant, breastfeeding, or planning to get pregnant, tell your doctor. They may adjust your dosage. 
• Do not drive, operate heavy machinery, or indulge in activities that require concentration because insulin may affect your vision. Do not do such things unless you determine how this medication affects you. 
• It is unsafe to consume alcohol while on treatment with Levemir as it may affect your blood sugar levels.  
• Do not change your insulin regimen, including manufacturer, strength, or type of insulin. Any change in the schedule may impact your sugar levels and increase the chances of hypoglycemia or hyperglycemia. 
• Hypoglycemia may impair concentration, increasing risk. So, avoid driving or operating heavy machinery that requires alertness. 
• Insulin medications may cause severe skin redness, itching, rash, or swelling at the injection sites. If this irritation persists, call your doctor right away.
• You may experience low blood sugar during your treatment with Levemir flextouch insulin detemir injection. If you suspect any of the following symptoms, talk to a medical practitioner:
  • Behavioral changes
  • Difficulty concentrating
  • Anxiety
  • Blurred vision
  • Drowsiness
  • Excessive sweating
  • Rapid heartbeats
  • Feeling hungry
  • Persistent headache
  • Nausea
  • Nervousness
  • Nightmares
  • Restless sleep
  • Shakiness
  • Weakness
  • Slurred speech 
• If you are unable to access medical facilities right away, you can manage your blood sugar levels by eating glucose tablets, honey, sugar cubes, juices, or sugar mixed in water. These steps will relieve some of the symptoms, making you feel better.
• Avoid using a glucagon kit in normal situations, as it is an emergency kit used in situations when patients are experiencing symptoms like seizures or become unconscious.

What Are the Contraindications of Levemir?

This medication is contraindicated in certain patients. So, if you plan to buy Levemir online, ensure that you are not on the following list:

• Do not take this medication if you have hypersensitivity reactions to insulin detemir or other ingredients in Levemir’s formulation. 
• If you are having episodes of hypoglycemia, avoid using this insulin.

What If You Miss a Dose of Levemir?

• It is crucial to take Levemir on time for safe and efficient medication use.
• If you missed a dose of Levemir, taking it as soon as possible is essential. 
• However, if it is almost time for your next dose of Levemir, you may skip the missed dose and take the next dose as per your dosing schedule. 
• Do not take two doses of the same medication to compensate for the missed dose. 

[Note: If you have missed a medication dose and are unsure when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Levemir?

Overdose of insulin may lead to hypoglycemia, which, if left untreated, may cause hypoglycemia and hypokalemia. If someone has taken the medication more than recommended, immediately seek medical assistance. If someone has passed out, has trouble breathing, or can’t be woken up, call 911 or head to the nearest emergency room. 

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How Should Levemir Be Stored?

• You should keep all insulin, including Levemir, in a safe place, away from the sight and reach of children. 
• Unopened Levemir vial and FlexTouch pen should be kept in the refrigerator. This way, it is suitable for use until its expiration date. 
• Do not allow Levemir to freeze. Do not use it if it is frozen. 
• If it is frozen, do not use the product; discard it safely and get a new one from your pharmacist. 
• Unopened Levemir may also be kept at room temperature, but it is only suitable for 42 days when kept this way. 
• While in use, the Levemir vial and FlexTouch pen should be kept at average temperature in a dark and dry place, away from direct light, excess heat and moisture. 
• Do not keep the pen with a needle attached to it. Permanently remove the needle and replace the cap after use. 
• Do not keep medications that are outdated or no longer needed. Dispose of it safely. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

What Drugs Interact with Levemir?

Levemir flextouch insulin detemir injection can have several interactions if taken with other drugs. These interactions may either increase the risk of developing severe side effects or affect how the medication works. Some of these drugs are mentioned below:

• • Thiazolidinediones: It is a class of drugs, and co-administering Levemir with TZDs may lead to fluid retention and raise the chances of heart failure. Patients with existing heart problems are at high risk of experiencing severe side effects. Some of the TZDs are:
    • Pioglitazone hydrochloride
    • Rosiglitazone maleate
  • Diabetes Medicines: Taking insulin detemir with other diabetes medications can lower your blood sugar levels to extreme levels, also known as hypoglycemia. If you are taking any of the following drugs, consult a medical professional. They will adjust the dosage accordingly.
    • Metformin
    • Glipizide
    • Liraglutide injection
    • Pramlintide acetate
  • Heart or Blood Pressure Drugs: If you take Levemir with heart or blood pressure medications, you may experience increased effects of the diabetic medicine, causing low blood sugar levels. Examples are:
    • Captopril
    • Lisinopril
    • Metoprolol
    • Atenolol 
  • Antibiotics: Similarly, co-administration of antibiotics with insulins-based medications like Levemir increases the effects of Levemir. Some of its examples include:
    • Zonisamide
    • Sulfamethoxazole/trimethoprim
      Sulfisoxazole
  • Steroids: Discontinue using steroids before you buy Levemir insulin, as combining steroids with diabetes medication may reduce the effects of Levemir. This can result in hyperglycemia. Some of the examples of steroids may include:
    • Hydrocortisone
    • Prednisone
    • Methylprednisolone
  • Diuretics: Do not take this medication with water pills. Doing so may lower the effectiveness of Levemir, causing high blood sugar. Its examples include:
    • Hydrochlorothiazide
    • Furosemide
  • Psychiatric Drugs & Hormone Therapies: Taking these two classes of drugs with insulin detemir may result in the reduced effects of Levemir. As a result, patients may experience high blood sugar. Some of the examples of these drugs are:
    • Thyroid hormones, including levothyroxine
    • Estrogen or progestogen
    • Olanzapine
    • Clozapine

• Other Drugs: 

• • Antidepressants 
  • MAOIs
  • Pasireotide 
  • Sulfasalazine
  • Corticosteroids 
  • HIV protease inhibitors 
  • Isoniazid 

What Are the Other Levemir Interactions?

Other than the above drugs, insulin detemir can also interact with certain substances or medical problems. These interactions are as follows:

• Alcohol: While there are no known interactions between Levemir and alcohol, it can affect your blood sugar levels, resulting in hypoglycemia and hyperglycemia. This depends on how much or how often you consume alcohol. Moreover, patients with uncontrolled diabetes, triglycerides, nerve damage, or pancreatitis should avoid alcohol. Note that limited consumption does not affect glycemic control; consult a medical professional if you are an addict.  
• Diseases: Not all patients can take Levemir to manage their glucose levels. Certain medical conditions may interact with insulin detemir. These are:
  • Renal/Liver disease
  • Hypoglycemia
  • Hypokalemia

[Note: This isn’t a complete list, and there could be other drugs that interact with Levemir. Tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Levemir Alternatives?

Levemir is not suitable for every patient due to varying body needs and medical conditions. This medication contains certain active and inactive drugs that may interact with your body and cause severe side effects. That’s where patients choose drug alternatives. These substitute medications are decided by a medical professional based on each patient’s response to the treatment. Here are some of the drugs that you can take in place of Levemir:  

• Lantus (insulin glargine)
• Tresiba (insulin degludec)
• Metformin (metformin hydrochloride)
• Ozempic (semaglutide)
• Rybelsus (semaglutide)
• Victoza (liraglutide)
• Januvia (sitagliptin phosphate)
• Basaglar (insulin glargine)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Levemir Cost & Coupons

Insulin-based medications like Levemir are expensive drugs that every patient can not afford. Therefore, people often use health insurance plans to manage the high-end Levemir flexpen prices. However, the problem arises when these medications are not included in the medical coverage. This leaves patients with no option but to spend thousands of dollars on their medications. To avoid such problems, you can buy Levemir from trusted pharmacies like Polar Bear Meds. Here, you will get the most affordable insulins without compromising on the quality. Moreover, if you are living in America, you can enjoy a 10% discount on Levemir by using the coupon code “WELCOMEPB10.” 

Frequently Asked Questions

Is it necessary to take Levemir with food?

It is important to remember that when taking Levemir once daily, you should inject the insulin at bedtime or mealtime. (Levemir may be considered an intermediate-acting insulin if taken in smaller doses.) If taking Levemir twice daily, you should take the evening dose either when you eat at dinner, at bedtime, or 12 hours after taking the morning dose.

Do you need to refrigerate Levemir?

It is recommended that you keep your Levemir® FlexPen® in a refrigerator at a temperature of 2°C to 8°C or at a temperature below 30°C while using it or keep it at a temperature below 30°C when not in use. When refrigerating medicines, keep them away from the cooling element, do not freeze them, and never dispose of drugs in wastewater or household waste. Lastly, if you are considering buying Levemir, use Levemir insulin coupons for discounted medication.

How does Levemir affect your weight?

A common side effect of Levemir is weight gain. This is generally a side effect that occurs when any insulin is taken, including Levemir. There have been studies showing that Levemir can cause small increases in weight in people with diabetes type 2 or type 1. However, this type of long-acting insulin causes less weight gain than other types of long-acting insulin.

Is Levemir hard on the kidneys?

Levemir is a long-acting insulin used to manage glycemic control in patients with diabetes mellitus. No specific reports indicate that Levemir is hard on the kidneys. In fact, managing sugar levels helps prevent kidney damage caused by unstable diabetes (the main cause of diabetic nephropathy). However, if you have existing kidney problems, you may need dosage adjustments to avoid potential risks.  

What is the onset of Levemir?

Onset indicates the time it takes for insulin to show its effects or lower blood sugar levels after administration. The onset of Levemir occurs between 1 and 2 hours after injecting the dose. This medication lasts up to 24 hours, providing a steady level of insulin all over the day. However, it is important to note that the individual response to the medication may vary. Therefore, always check your sugar levels and share the reports with your doctor. 

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