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Human Insulin
Novolin
Novolin is FDA-approved for managing diabetes mellitus. It may also be used to treat hyperosmolar hyperglycemic state and ketoacidosis. It contains insulin isophane and is available in different forms, such as Novolin R (Regular insulin) and Novolin N (NPH insulin), as well as combinations of these two types. Administer novolin subcutaneously 30 minutes before meals. The medication dosage depends on the patient’s age, condition, needs, and response to the treatment. If you plan to buy Novolin insulin online, consult a doctor regarding its usage, potential risks, and benefits, and stick to their guidance regarding storage, disposal, and dosage. Doing so may avoid any serious complications, ensuring the safe use of the medication.
Product Overview
Novolin is an essential insulin-based medication used for the management of diabetes mellitus. It comprises insulin analogs that closely mimic the body’s natural insulin, effectively regulating blood sugar levels by facilitating the breakdown of food components and promoting sugar absorption from the bloodstream. Novolin is available in different formulations, including Novolin R (Regular insulin) and Novolin N (NPH insulin), as well as combinations of these two types.
The strength of Novolin varies depending on the specific product, with options like Novolin 70/30 providing a mix of 70% NPH insulin and 30% regular insulin. Patients are advised to administer Novolin subcutaneously, approximately 30 minutes before meals, with dosage individualized based on metabolic needs and blood glucose monitoring results. Novolin is suitable for individuals with diabetes mellitus who require insulin therapy for blood sugar control.
However, patients should be aware of potential side effects such as hypoglycemia, weight gain, and allergic reactions. It’s essential to take precautions, including regular blood sugar monitoring and not sharing insulin pens or syringes. In case of a missed dose, follow the guidance of a healthcare provider, and for overdose, seek immediate medical attention. Insulin isophane human (the generic name for Novolin) should be appropriately stored, with unopened refrigerated and opened vials kept at room temperature for a limited time. Always consult with a healthcare professional for personalized advice and dosage adjustments.
What Are the Uses of Novolin?
This medication is used for the following conditions:
- Type 1 and type 2 diabetes mellitus.
- Hyperosmolar hyperglycemic state
- Diabetic ketoacidosis
[Note: Do not take Novolin without consulting your doctor. They will determine whether you need this medication based on your conditions.]
What Are the Forms & Strengths of Novolin?
Novolin comes in the following forms and strengths:
- Novolin R: 100 units/ml
- Novolin N: 100 units/ml
- Novolin 70/30: 100 units per mL with 70% NPH insulin and 30% regular insulin.
What Is the Recommended Dosage for Novolin?
Novolin dosage may vary based on the patient’s age, weight, medical conditions, and the medication form they are taking. The section below covers the average doses of Novolin for different patients. If you have been prescribed a different dose, do not try to change it unless your doctor advises otherwise.
Type 1 Diabetes
- Initial dose: 0.5-1 unit/kg/day SC.
- Nonobese individuals: 0.4-0.6 unit/kg/day
- Obese individuals: 0.8-1.2 units/kg/day
Type 2 Diabetes
- Morning Dose: two-thirds of daily insulin SC.
- Evening Dose: one-third of daily insulin SC
[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]
How to Use Novolin?
Proper administration steps are essential to maintain the safety of your medication. If you decide to buy Novolin insulin online, ensure that you are following the correct administration steps, which are as follows:
- Carefully read the patient information leaflet that comes along with your prescription and follow the instructions given by your doctor.
- If you have any questions regarding medication usage, missed doses, and interactions, ask your doctor or healthcare provider before use.
- Before using, your doctor will show you how to administer the insulin safely and effectively.
- Before using, you may gently roll the cartridge or vial by turning it upside down. Do not shake the medication.
- Before using, check the medication for any unusual change in appearance. Do not use it if it is discolored, clumpy, or has particles.
- Properly wash your hands with soap and water before administering the insulin.
- Clean the site with a cotton swab and rubbing alcohol before injecting.
- Constantly rotate the injection site to avoid getting lumps and pits under your skin.
- As directed by your doctor, inject this medication under the skin of the abdomen, front thigh, buttocks, or upper arm.
- Do not inject the insulin into a muscle or vein.
- Do not inject into skin that is red, torn, damaged, itchy, swollen or has stretch marks in it.
- You should not inject cold insulin as it may be painful. It is essential to store opened or in-use medications at average room temperature.
- Novolin may be mixed only with certain insulins and medications like insulin regular.
- You should always draw the insulin regularly into the syringe, followed by the long-acting insulin.
- NPH insulin can also be combined with Regular insulin (R). These two insulin types (NPH and R) are commonly administered in the same syringe for optimal therapeutic outcomes.
- Novolin should not be mixed with other insulins when administered intravenously.
- You should measure your dose very carefully, as even a tiny change in the dosage may result in unwanted side effects.
[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]
How Does Novolin Work?
Insulin isophane human (the generic name for Novolin) contains insulin analogs that work the same as insulin that naturally occurs in the body. It regulates blood sugar by breaking down carbohydrates, fats, and proteins and facilitates the absorption of sugar from the bloodstream. Regular insulin is fast-acting, commencing its action within 30 minutes and maintaining its effectiveness for up to 8 hours. In contrast, insulin isophane (NPH) takes around 90 minutes to begin working and offers sustained blood sugar control for approximately 24 hours. When used in combination, these two insulins can provide enhanced blood glucose management. Novolin 70/30 works swiftly and provides a long-lasting, consistent effect throughout the day. Additionally, it helps minimize the fluctuations in blood sugar levels that can happen while using insulin analogs alone.
Important Safety Information for Using Novolin
What Are the Side Effects of Novolin?
Common Side Effects: Like all medications, Novolin can lead to several common side effects. These effects are generally short-term and do not require immediate medical attention. Some of these side effects may include:
- Low Blood Sugar: Too much insulin administration may cause a sudden drop in your sugar levels. To avoid this side effect, follow the dosage as prescribed by your doctor.
- Weight Gain: Insulin helps the body store sugar from food. The more insulin you take, the more sugar your body will store as fat, leading to weight gain over time.
- Injection Site Reactions: Daily insulin administration may irritate the skin and cause several reactions at the injection site. These reactions may include thickening or hollowing of skin.
- Allergic Reactions: Certain Novolin ingredients may react with your body, causing symptoms like skin itching and mild skin rash. This side effect is very common at the start of the treatment as your body tries to adjust to the medication.
Serious Side Effects: While rare, these side effects can cause life-threatening situations if left untreated. Therefore, if you suspect any unwanted symptoms or signs after using Novolin, seek immediate medical attention. Some of the serious side effects of Novolin may include:
- Seizures: Sudden drops in your blood sugar levels can mess up your brain functioning. This can lead to seizures in certain patients.
- Severe Allergic Reaction: Novolin contains certain active and inactive ingredients that may interact with your immune system, causing severe allergic reactions. Therefore, patients with existing hypersensitivity reactions should consult their doctor before they plan to buy Novolin insulin online.
- Severe Hypoglycemia: While mild low blood sugar levels can be treated at home, a drastic drop in these sugar levels can cause various life-threatening complications. Contact your doctor if you experience confusion, excessive sweating, nausea, or dizziness.
- Hypokalemia: Insulin can transfer potassium from your blood into the cells, reducing potassium levels. This reduction may affect your muscle and heart functioning.
- Edema: Novolin may cause the body to store excess water and salt. This accumulation may result in swelling in different body parts, especially in the hands or feet. This side effect can become severe if left untreated. Consult a doctor before using this medication.
[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]
Are There Any Warnings for Novolin?
Insulin isophane human (the generic name for Novolin) has several warnings. Patients using this medicine should be aware of the following safety information to avoid potential risks:
- Novolin is an insulin for subcutaneous use only. Do not use intravenously or intramuscularly.
- It is not recommended for use in patients with diabetic coma.
- Infections: Do not share a Novolin pen or syringe between patients, even if the needle is changed, as it may cause infection to spread from one person to another.
- Hypoglycemia: Co-administration of Novolin with other diabetic medicines may cause low blood sugar, which can become dangerous when it gets severely low. Make sure that you know how to manage hypoglycemia, as this condition can happen at any time.
- Monitor closely and increase blood glucose monitoring frequency with changes in insulin regimen.
- Low Potassium Levels: This medication can lower your potassium levels, and patients taking potassium-lowering drugs are at high risk of this side effect. When considering treatment with Novolin, consult a doctor. They will closely monitor potassium levels in at-risk patients. Such patients may require dosage adjustments.
- Allergic Reactions: Novolin may cause allergic reactions in some patients. If reactions, such as severe itching, redness, swelling, difficulty swallowing, or breathing occur, discontinue the medication and seek immediate medical attention.
- Heart Failure & Swelling: Co-administration of Novolin with thiazolidinediones can cause fluid retention. This condition may lead to adverse reactions in patients with heart failure, as excess fluid can worsen heart failure. Talk to your doctor regarding this for detailed guidance.
What Are the Novolin Precautions?
Before using this medication, ensure to follow the below precautions, as it can help minimize the risk of serious complications:
- Do not mix Novolin with other medications or insulin unless instructed by your doctor.
- Before each injection, ensure you have the correct insulin type and dosage.
- Before use, check your insulin for any unusual change in appearance. Do not use it if it is discolored, cloudy, or has particles.
- Before using the insulin, let your doctor know if you have problems related to the kidney, liver or heart.
- Do not use insulin if you have severe low blood sugar.
- Do not inject Novolin through insulin pumps.
- Do not try to alter your doses, as dosage adjustments will be based on the patient’s metabolic needs, blood glucose monitoring results, and glycemic control goals.
- Constantly rotate the injection spot to prevent lumps and pits from forming under your skin.
- It is unsafe to consume alcohol while receiving treatment with Novolin.
- Do not drive, operate heavy machinery or indulge in activities that require your attention unless you determine how the insulin affects you.
- Do not change the insulin’s brand, type, and dosage without consulting your doctor.
- You should check your blood glucose levels regularly and share the report with your doctor to help them determine the correct dose for you.
- To get the most benefit from your medication, it is essential to use this medication regularly.
- If you are pregnant, planning to get pregnant or if you are breastfeeding a baby, let your doctor know; they are most likely to make adjustments to your existing dosage.
- Let your doctor know if your condition does not improve or worsen.
What Are the Contraindications of Novolin?
Novolin is contraindicated for use in patients:
- Who has a known hypersensitivity to Novolin or any of its excipients.
- During episodes of hypoglycemia
What If You Miss a Dose of Novolin?
- If you missed a dose of Novolin, take it as soon as you remember.
- However, if it is almost time to take your next dose, you can skip the missed dose and take the next dose of Novolin as per your dosing schedule.
- Contact your doctor immediately if you are still uncertain when to take your missed dose.
[Note: If you have missed a medication dose and are unsure when to take the next one, immediately consult your doctor or pharmacist.]
What Happens If You Take Too Much of Novolin?
If you take any insulin, including Novolin, it can cause hypoglycemia and hypokalemia. You should not miss a meal or indulge in strenuous physical activity. Symptoms of an overdose happen suddenly. Look for signs and symptoms such as cold sweat, fatigue, tremors, weakness, confusion, blurred vision, nausea, and anxiousness. Severe hypoglycemia, if left untreated, may result in unconsciousness, coma, and death. If the patient has passed out, is having seizures, has difficulty breathing, or can’t be woken up, immediately seek medical assistance. You can call 911 or head to the nearest emergency room.
[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]
How Do You Store Novolin?
For the safe and effective use of your medication, follow the below storage guidelines:
- Keep unopened Novolin at a temperature below 77°F for up to 6 weeks.
- Vials that are not in use or unopened may be kept in the refrigerator until expiration.
- It may also be kept at room temperature for up to 42 days.
- Safely dispose of the used vials after 42 days, even if it has insulin.
- Unopened pre-filled insulin pens may be kept in the refrigerator until their expiration date or at average room temperature for up to 28 days.
- Do not refrigerate opened and in-use Novolin pens, cartridges, and vials.
- Keep the medication in a dark and dry place, away from direct light, excess heat, and moisture.
- Keep all insulins, including Novolin, in a safe place away from the children’s sight and reach.
- Do not freeze the insulin; do not use it if frozen, as it may be painful.
- Throw away the frozen insulin and get a new one from your pharmacist.
- Dispose of all syringes, injectable pens, and needles in a sharps container.
- If you do not have a sharps container, you can use a container made of hard plastic and a tightly fitting lid.
- For more information on the proper disposal of insulin, contact your healthcare provider or local waste disposal company.
[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]
What Medications Interact with Novolin?
Drug interactions occur when you take two or more medications together. These interactions can either affect the functioning of the drug or increase the risk of experiencing severe side effects. If you plan to buy Novolin insulin online, ensure that you are not using the below-mentioned drugs:
- Antidiabetic agents
- ACE inhibitors
- Antipsychotics
- Alcohol
- Angiotensin II receptor-blocking agents
- Beta-blockers
- Corticosteroids
- Disopyramide
- Diuretics
- Fibrates
- Estrogens
- Glucagon
- Fluoxetine
- Oral contraceptives
- Protease inhibitors
- Monoamine oxidase inhibitors
- Pentoxifylline
- Pramlintide
- Reserpine
- Salicylates
- Somatostatin analog
What Are the Other Novolin Interactions?
Besides the above drugs, Novolin also has some disease interactions, which are as follows:
- Renal/liver disease
- Hypokalemia
- Hypoglycemia
[Note: This isn’t a complete list, and there could be other drugs that interact with Novolin. Tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]
What Are the Novolin Alternatives?
Here are some of the alternatives that you can take in place of Novolin:
- Humulin N (insulin isophane)
- Tresiba FlexTouch (insulin degludec)
- Lantus (insulin glargine)
- Novolog (insulin aspart)
- Apidra (insulin glulisine)
- Humalog (insulin lispro)
[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]
Novolin Cost & Coupons
Novolin may be an expensive insulin medication that is not affordable for every patient. That’s why many Americans use health insurance plans to manage the cost of these expensive drugs. However, not all medications are included in these medical coverages, leaving patients with high-end expenses. To manage these costs, you can turn to affordable Canadian pharmacies like Polar Bear Meds. Here, Americans can buy Novolin insulin online at much more reasonable rates. Moreover, customers can enjoy 10% discounts on their first order by using the coupon code “WELCOMEPB10.”
Frequently Asked Questions
Is it necessary to refrigerate Novolin 70/30 Insulin?
All unopened Novolin 70/30 should be kept in the refrigerator b/w 36°F & 46°F (2°C and 8°C). It should not be frozen. Novolin 70/30 should not be used once it has been frozen. If refrigeration is not feasible, storing the unopened vial at room temperature for up to 42 days (6 weeks) is possible, provided that the temperature is kept below 77°F (25°C).
How long can a Novolin Insulin pen be kept at room temperature?
The storage parameters (unopened) of Novolin 70/30 insulin are as follows:
- Keep it below 77°F (25°C) for up to 6 weeks.
- Keep vials away from direct light and heat and from the presence of other products.
- Throw away fully used vials after six weeks (42 days) of use, no matter how much insulin is left in the vial.
How does Novolin Insulin differ from other insulins?
Compared to faster-acting insulins, Novolin ge NPH is a longer-acting insulin, which means that it will lower your blood sugar within 112 hours of being taken, and the effects will last approximately 24 hours. Novolin ge NPH is often used with fast-acting insulins to achieve the best results.
Can you take Novolin 70-30 more than once a day?
There is usually no need to administer more than two Novolin 70-30 injections during the day. However, you should administer one every two to three hours, depending on the type of meal you will consume. It is usually recommended to administer Novolin 70/30 insulin two times a day.
Is Novolin and Novolog the same?
Both Novolin and Novolog are manufactured by the same company, Novo Nordisk, but their mechanism of action are not different. Novolin is a traditional insulin that acts slowly and lasts for a longer period. Whereas, Novolog is a rapid acting insulin that starts working rapidly. This insulin is taken just before meals to manage blood sugar spike after eating.
Is Humulin and Novolin the same?
No, Humulin and Novolin are not the same. Both medications are used to manage glycemic control but have different insulin types, including rapid-acting, intermediate-acting, and premixed formulations. Although the active ingredients in Humulin and Novolin are the same, i.e., human insulin, they have slight differences slight differences in their onset of duration. Therefore, always consult a medical professional on which insulin to use.
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