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What Is Tresiba Insulin and What Is It Used For?
The prescription Tresiba FlexTouch pen is designed explicitly as a long-acting insulin to manage elevated blood sugar levels in both adults & children (aged 1 year and older) diagnosed with diabetes. It is essential to note that individuals experiencing diabetic ketoacidosis (it is a condition characterized by increased ketones in the urine or blood) should not use Tresiba.
In children under the age of 1, healthcare providers have not established the safety and efficacy of Tresiba, and they do not recommend its usage in this age group. Tresiba is available in two concentrations: 200 units/mL and 100 units/mL, providing options for tailored treatment under medical supervision.
How Does Tresiba (Insulin Degludec) Injection Work?
It is a once-daily injectable insulin that lowers blood sugar by slowly and steadily releasing it throughout the day, similar to the body’s insulin. It is available in a vial or a FlexTouch pen and is used to help your blood sugar reach your cells and provide you with the energy that fuels your body. Once you inject Tresiba, it helps your blood sugar get to your cells.
Dosage and Uses of Tresiba FlexTouch pen
- Read the Instructions for Use carefully.
- Take the Tresiba pen exactly as prescribed by your healthcare provider.
- Do not convert your dose; the counter shows your selected dose in units.
- Know your insulin type and strength; consult your healthcare provider before changing it.
Missed Dose (Adults):
- If you miss a dose, take it as soon as you remember.
- Ensure there’s an 8-hour gap between doses.
Missed Dose (Children):
- For missed doses in children, contact the healthcare provider for guidance.
- Children needing less than 5 units should use a Tresiba U-100 vial.
Blood Sugar Monitoring:
- Regularly check your sugar levels of blood as per your doctor’s instructions.
- Inject the Tresiba pen subcutaneously in the thighs, upper arms, or abdomen.
- Rotate injection sites to avoid skin issues like lipodystrophy or cutaneous amyloidosis.
- Do not inject in areas with pits, lumps, tenderness, bruising, or damaged skin.
- Never inject a Tresiba pen into veins or muscles.
Needle and Syringe Safety:
- Do not share needles or syringes; it can cause serious infections.
- Never take insulin Tresiba out of the FlexTouch pen using a syringe.
Always consult your healthcare professional for personalized guidance on your Tresiba usage.
Side Effects of Tresiba Medication
Tresiba has the potential to cause severe, life-threatening side effects, such as:
Low Blood Sugar (Hypoglycemia):
Indications of low blood sugar encompass dizziness, light-headedness, sweating, confusion, headaches, blurred vision, slurred speech, shakiness, rapid heartbeat, anxiety, irritability, mood swings, and hunger.
Low Potassium Levels (Hypokalemia):
Tresiba may lead to low potassium levels in the blood.
Heart Failure Risk with Thiazolidinediones (TZDs):
Some individuals may experience heart failure, even if they have no prior history of heart issues, when taking Tresiba with TZDs. Symptoms of worsening heart-failure include: shortness of breath, fatigue, swelling in the ankles or feet, and sudden weight gain.
Adjustment in Insulin Dose:
Changes in physical activity, increased stress, alterations in diet, weight fluctuations, or illness might necessitate adjustments in your insulin dose.
Common Side Effects:
Common side effects encompass severe allergic reactions, reactions at the injection site, skin abnormalities such as thickening or pits (lipodystrophy), itching, rash, swelling in the hands and feet, and weight gain.
Seek immediate medical support if you experience difficulty breathing, rapid heartbeat, facial, tongue, or throat swelling, profuse sweating, extreme drowsiness, dizziness, or confusion.
Warnings and Precautions of Tresiba FlexTouch Pen
Before considering Tresiba, it’s crucial to be aware of certain warnings and precautions:
- Firstly, do not take Tresiba insulin if you are experiencing a low blood sugar (hypoglycemia) episode or if you have a known allergy to Tresiba or any of its components.
- Additionally, it’s vital to inform your healthcare provider about your medical history.
- If you are pregnant, planning to become pregnant, or currently breastfeeding, your healthcare provider needs to know.
- It’s equally important to disclose all the medications you are taking, whether they are new prescriptions, over-the-counter medicines, vitamins, or herbal supplements.
- Your healthcare provider can provide tailored guidance on managing low blood sugar and ensure your safety while using Tresiba.
Consult your doctor always for personalized advice regarding your specific medical situation.
Tresiba Insulin Interactions
Tresiba has the potential to interact with various substances, including other insulin products, beta-blockers, clonidine, guanethidine, reserpine, and other antidiabetic agents. It is crucial to inform your doctor about all medications & supplements you are using to prevent potential interactions. Additionally, interactions can occur with:
- Somatostatin Analogs
- Monoamine Oxidase Inhibitors
- ACE Inhibitors
- GLP-1 Receptor Agonists
- Oral Contraceptives
- Thyroid Hormones
- Angiotensin II Receptor Blocking Agents
- DDP-4 Inhibitors
- SGLT-2 Inhibitors
- Protease Inhibitors
- Sympathomimetic Agents
- Atypical Antipsychotics
- Lithium Salts
Frequently Asked Questions
What are the recommended dosages and uses of Tresiba medication?
For individuals with type 1 diabetes who have not previously used insulin, the initial Tresiba® dosage typically ranges from one third to one half of the total daily insulin requirement. The remaining portion of the daily insulin requirement should be administered as short-acting insulin, divided between each meal.
As a general guideline, the initial total daily insulin dose for insulin-naive patients with type 1 diabetes can be calculated based on 0.2 to 0.4 units of insulin per kg of body weight. In the case of insulin-naive patients with type 2 diabetes, the recommended starting dose of Tresiba® is 10 units once daily.
What are the potential side effects of using the Tresiba Flextouch Pen?
Some most of the common side effects of Tresiba are:
- Hypoglycemia (sometimes due to Medication errors)
- Hypersensitivity reactions
Is it safe to store Tresiba Insulin without refrigeration?
Yes, Tresiba (insulin Degludec) remains viable for up to 56 days (8 weeks) when stored at room temperature (below 86°F [30°C]), both when opened and unopened. Proper storage at room temperature provides flexibility in managing your medication. It’s important to note that this extended shelf life allows for more convenient usage, especially when refrigeration isn’t readily available.
However, it is crucial to discard Tresiba after this period to ensure its effectiveness and safety. Adhering to the recommended storage guidelines guarantees the potency and reliability of the medication, promoting optimal health management for individuals with diabetes.
Is weight gain a side effect of insulin Tresiba?
Yes, taking insulin-like Tresiba can lead to weight gain. Research studies have shown that individuals with type 1 or type 2 diabetes experienced weight gain while using a Tresiba pen. However, it’s important to note that weight loss is not a documented side effect of Tresiba insulin; if you lose weight while on Tresiba medication, it’s advisable to consult your doctor, as they may need to adjust your treatment plan accordingly.
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