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What is Aldomet?

Aldomet is an antihypertensive medication employed to manage high blood pressure and diminish the risk of strokes, heart attacks, and kidney issues. The medication operates by relaxing blood vessels for more effortless blood flow and should be taken as recommended by a physician or pharmacist, usually 2 to 4 times per day, with the initial dose best taken in the evening to reduce side effects.

Dosage, Uses, and Storage of Aldomet Canada

The suitable dosage for Aldomet fluctuates based on individual response and medical condition, but it is usually taken twice daily with food. It may be beneficial in treating other ailments, such as angina or migraines. However, due to potential side effects, caution must be taken when prescribing it for these purposes. Besides proper dosing instructions, it is critical to store Aldomet properly; keep it far from children’s reach and store it at room temperature without light and humidity.

Dosage of Aldomet

Methyldopa tablets are typically administered in 500mg doses, and the starting amount is generally 250 mg two to three times a day for two days. However, it is critical to be mindful that methyldopa can produce drowsiness when commencing or augmenting the dosage, and elderly patients should not surpass 250 mg daily. Those with renal impairment may necessitate smaller dosages too. Additionally, methyldopa has contraindications for those with active liver disease, hypersensitivity, depression, on medicine with MAOIs, or with a catecholamine-secreting tumor or porphyria. Furthermore, overdosage of Aldomet can cause acute hypotension due to its influence on blood pressure control; thus, this medicine should be taken with care, particularly for those already on antihypertensive medicines such as hydrochlorothiazide once daily.

Uses of Aldomet

Methyldopa, otherwise known as Aldomet, is frequently used to address hypertension and its attendant issues, such as:

  • Strokes
  • heart attacks
  • renal issues

How to store Aldomet

It is recommended to store Aldomet tablets in a well-closed container at a controlled room temperature. This antihypertensive drug, containing the active ingredient methyldopa, is a white to yellowish white, odorless fine powder. Keeping Aldomet tablets in a cool place away from exposure to light and humidity will help ensure their effectiveness when taken as designated.

Side Effects of Aldomet

Common side effects of Aldomet include:

  • Dizziness
  • Lightheadedness
  • Headache

Additional potential side effects of this medication may incorporate: Muscle spasms – intense muscle contractions that can cause pain or impair the movement of the affected area, potentially linked with other symptoms such as:

  • Fever
  • Confusion or loss of coordination
  • Mental/mood changes – apprehension
  • Depression or suicidal thoughts
  • sleeping difficulties
  • hallucinations
  • decreased concentration

Rarely, it can cause liver disease or reduce red blood cell count, leading to anemia and fatigue. Allergic reactions necessitate urgent medical attention if symptoms occur.

Warnings and Precautions of Using Aldomet from Canada

Aldomet, obtainable for purchase online in Canada, necessitates care. Those suffering from active liver affliction, pheochromocytoma, or porphyria should be monitored vigilantly when taking Aldomet, as it can raise the probability of detrimental consequences. Moreover, people should talk with their healthcare provider before starting the application of this medication to debate prospective hazards and potential advantages.

Active liver disease

Methyldopa is contraindicated for those dealing with active liver disease or past difficulties related to methyldopa-associated issues. This is due to the possibility of worsened symptoms and other possible hazards. Patients with a history or susceptibility to liver disease should be cautious when taking methyldopa, as it can cause increased levels of transaminases, alkaline phosphatase, and bilirubin, potentially resulting in jaundice, hepatic encephalopathy and even, in isolated cases, hepatotoxicity. Monitoring of signs of liver injury as well as abnormal laboratory results should be done periodically when taking this drug. Should any signs or symptoms appear, the medication should be stopped right away.


Pheochromocytoma is a rare tumor of the adrenal gland that can cause excessive amounts of catecholamines to be released into the bloodstream, leading to hypertension. Clinical studies show that administering methyldopa can reduce the excretion of vanilmandelic acid (VMA) and metanephrine (MN), and normetanephrine (NMN). It also decreases blood pressure but does not prevent spontaneous paroxysms or interfere with histamine tests. Additionally, it interferes with the determination of catecholamines in blood and urine by fluorometry.

Methyldopa’s effects on pheochromocytoma include:

  • Transiently reducing VMA excreted after histamine injection
  • Inhibiting decarboxylation of aromatic amino acids
  • Interfering with the storage or release of catecholamines
  • Persisting in urine for about four days after discontinuation


Porphyria is a hereditary metabolic ailment that can cause various indications, from abdominal pain to mental disturbances. Analysis should be confirmed before finding suitable hypertension and heart failure therapy.

Porphyrias are rare disorders that mainly affect the skin or nervous system. These disorders are usually inherited, meaning they are caused by gene mutations NIH external link passed from parents to children.

Varied medications can be employed securely in porphyria, including thiazide diuretics, furosemide, certain beta blockers and ACE inhibitors, Eprosartan, candesartan, and valsartan rather than other ARB blockers, calcium channel blockers with wariness, prazosin or doxazosin; reserpine is safe, but methyldopa, hydralazine, dihydralazine, and clonidine should be avoided.

Drug Interactions

Patients taking Aldomet should be wary of potential drug interactions, as it may interact with:

  • MAOIs
  • Lithium
  • Haloperidol
  • Levodopa
  • Tolbutamide
  • respiratory medicines
  • beta-blockers
  • phenothiazines
  • barbiturates
  • tricyclic antidepressants

Careful monitoring is advised when utilizing this medication alongside any of these drugs. It is essential to consult a doctor before initiating or adjusting any medication regimen while taking Aldomet. Serious side effects can occur if the drug interrelates with other medications detrimentally.

Frequently Asked Questions

Is Aldomet available without a prescription?

Aldomet is a medication requiring a valid script from a physician or medical practitioner for acquisition. Without such documentation, it is not accessible.

Is Aldomet safe for pregnant and breastfeeding women?

Pregnant and breastfeeding women should consult their healthcare professional before consuming Aldomet. Its safety in this demographic has not been verified, which might enhance the probability of issues.

Are there any age restrictions for using Aldomet?

Aldomet might not be appropriate for those under 18 years due to a lack of data regarding its safety and efficacy. It is wise to seek advice from a medical expert before taking Aldomet.

What are the long-term effects of taking Aldomet?

Taking Aldomet may lead to long-term consequences such as impaired kidney operation, augmented peril of infection, and anemia. Additional potential side effects may include enlargement, lightheadedness, and lassitude.


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