Abiraterone

Buy Abiraterone Online from Licensed Canadian Pharmacies

Abiraterone is a once-daily medication that helps adult men treat their advanced prostate cancer. It is available as 250 mg tablets and comes in a pack of 60 tablets. You can order Abiraterone from Canada to get it safely.

This medicine is only available with a valid prescription, and it works by blocking the production of male hormones (androgens) that fuel cancer growth. This further helps in slowing the disease and easing symptoms like bone pain and fatigue.

When you take this medication daily by mouth, usually with prednisone, it can delay chemotherapy and support a better quality of life. Doctors prescribe it as part of a broader cancer plan, often alongside hormone-lowering therapy.

Abiraterone, no doubt, is an effective medicine, but it may cause some side effects such as swelling, high blood pressure, or changes in liver function. For that, your health care provider will monitor your health condition regularly.

Drug Summary

What Is Abiraterone Used For?

Abiraterone is used to treat:

• Certain types of metastatic prostate cancer in adult men, together with a steroid such as prednisone.

Benefits of Abiraterone

• Slows cancer growth by blocking hormones that prostate cancer cells use as fuel.
• Treatment can delay the need for chemotherapy and help some patients maintain quality of life for a longer period.
• Abiraterone also helps in controlling cancer-related symptoms, such as bone pain and fatigue, as part of a broader treatment plan.
• You only have to take it once a day by mouth.
• When used correctly with ongoing hormone-lowering therapy or prior surgical castration, it provides more complete androgen blockade against the tumor.

Abiraterone Dosage for Prostate Cancer in Adults

• For castration-resistant and high-risk castration-sensitive:
• Take the total daily dose of 1000 mg (which is 4 tablets of 250 mg) once daily.
• Take it together with 5 mg prednisone (orally two times per day).
• For children: Use of Abiraterone is not recommended.

How Do You Take Abiraterone Tablets?

To get the best results with Abiraterone, use it following these guidelines:

• Read the leaflet (for patient information) included with the medication and ask your doctor if anything is unclear.
• Take Abiraterone tablets exactly as prescribed. Do not take more often than directed.
• Do not change the dose or schedule on your own.
• Take it at the same time every day to maintain the levels of this medication in your body.
• Swallow the tablet whole with water. You don’t have to split, chew or crush the tablets.
• Abiraterone is usually taken along with prednisone (a corticosteroid) to reduce certain side effects. Follow your doctor’s exact instructions for both medicines.
• You need to take this medicine on an empty stomach.
• Do not eat for 2 hours before taking Abiraterone.
• Do not eat for 1 hour after taking it.
• Your doctor may prescribe it alongside a gonadotropin-releasing hormone (GnRH) medicine (used to lower testosterone), or you must already have had surgical removal of the testes.

How Abiraterone Works

Abiraterone acetate is converted inside the body into Abiraterone, a medicine that blocks an enzyme called CYP17.

CYP17 is essential for making androgens (male hormones), including testosterone, in the testes, adrenal glands, and even within prostate cancer cells themselves.

Abiraterone inhibits CYP17 and sharply reduces androgen production. Since prostate cancer cells depend on these hormones as “growth signals,” lowering androgen levels slows down cancer growth or may stop it from progressing. This is why Abiraterone is classified as an androgen biosynthesis inhibitor. It reduces hormone production at the source rather than simply blocking hormone activity.

Blocking CYP17 also decreases cortisol (stress hormone). In response, the body increases ACTH (adrenocorticotropic hormone), which can raise mineralocorticoid levels. These are hormones that may cause fluid retention, high blood pressure, and low potassium (hypokalemia).

To balance these effects, doctors prescribe low-dose prednisone or methylprednisolone, which helps stabilize cortisol pathways and reduces unwanted side effects.

What Are the Side Effects of Abiraterone?

Common Abiraterone side effects may include:

• Swelling in the legs or feet (edema) or fluid retention
• Increased blood pressure (hypertension)
• Low potassium levels (sometimes cause weakness or muscle cramps)
• Fatigue or feeling unusually tired
• Joint or muscle pain
• Hot flashes or a feeling of warmth and flushing
• Digestive symptoms such as diarrhea, indigestion, or mild nausea
• Changes in liver blood tests (elevated liver enzymes)

Serious side effects (rare):

• Severe high blood pressure
• Signs of mineralocorticoid excess include:
• Significant fluid retention
• Sudden weight gain
• Worsening leg swelling
• Severe liver injury
• Adrenocortical insufficiency
• Serious heart problems
• Severe allergic reactions

Abiraterone Warnings

Consider these warnings before you use or order Abiraterone online from Canada:

• Abiraterone is indicated only for adult men. It must not be used in women or children.
• Strong CYP3A4 inducers (such as rifampin, carbamazepine, or phenytoin) can lower Abiraterone levels and reduce effectiveness. So avoid using it.
• Abiraterone plus prednisone or prednisolone should not be combined with radium Ra-223 dichloride. This combination has been linked to increased fractures and mortality.
• Use in patients with moderate hepatic impairment requires dose reduction and intensive monitoring. Use in severe hepatic impairment is generally avoided.
• Abiraterone inhibits CYP2D6 and CYP2C8, so combining it with medicines that strongly rely on these enzymes and have a narrow safety margin. It requires caution and often dose changes of the other drug.

Abiraterone is usually given by an oncology specialist as part of a comprehensive cancer plan, but here are other precautions that you need to take while or before you start using this medicine:

• This medicine is not safe in pregnancy. Women who are or could become pregnant should not handle broken or crushed tablets. If handling is necessary, use protective gloves.
• Men who have female partners and can become pregnant are typically advised to use an effective contraceptive (birth control like condoms) during treatment & for 3 weeks (at least) after the last dose.
• Your oncologist will check these functions regularly, especially during the first few months of therapy:
• Blood pressure
• Electrolytes (especially potassium)
• Liver function
• Never share Abiraterone tablets with anyone else.

Abiraterone Missed Dose

If you’ve missed one dose of Abiraterone, take it as soon as you remember on the same day, and then take your next scheduled dose at the usual time the following day.

Do not take extra tablets to catch up for the missed one. If you miss more than one dose, or if you are unsure how to resume, contact your oncology team. They’ll guide you properly.

Abiraterone Overdose

Taking more Abiraterone tablets than prescribed may raise the risk of serious problems, including very low or very high blood pressure, severe changes in potassium, heart rhythm problems, or liver injury. Symptoms may include:

• Dizziness
• Fainting
• Chest pain
• Shortness of breath
• Rapid or irregular heartbeat
• Extreme fatigue
• Yellowing of the skin or eyes

If you notice that you have overdosed on Abiraterone, stop taking the medication and call your local emergency services right away. In the U.S., call 911 or the Poison Control Center at 1-800-222-1222.

How to Store Abiraterone

If you order Abiraterone online from Canada, here’s how you should store it:

• Store these tablets at room temperature, typically up to 25°C (or up to 77°F).
• Do not use the tablets after the expiration date.
• Try not to store this medicine near the sinks, in bathrooms, or in any extreme conditions.
• Dispose of the tablets carefully as per your regional disposal guidelines.
• Keep these tablets away from pets and children.

Abiraterone Interactions

Abiraterone interacts with many other medicines largely because it is processed by and affects several liver enzymes (especially CYP3A4, CYP2D6, and CYP2C8).

Some examples of these interacting medicines include:

• Rifadin (rifampin)
• Tegretol (carbamazepine)
• Dilantin (phenytoin)
• Luminal (phenobarbital)
• Nizoral (ketoconazole)
• Norvir (ritonavir)
• Toprol-XL (metoprolol)
• Pamelor (nortriptyline)
• Actos (pioglitazone)
• Prandin (repaglinide)

Abiraterone Alternatives

Abiraterone alternatives may include:

• Xtandi (enzalutamide)
• Erleada (apalutamide)
• Nubeqa (darolutamide)
• Lupron Depot (leuprolide)
• Eligard (leuprolide)
• Firmagon (degarelix)
• Taxotere (docetaxel)
• Jevtana (cabazitaxel)

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