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Tocilizumab

Actemra

Experience effective relief from inflammatory conditions with the FDA-approved Actemra autoinjector, available online from Canada. Buy Actemra Prefill Autoinjector Online from Canada to manage rheumatoid arthritis, juvenile idiopathic arthritis, giant cell arteritis, and systemic sclerosis-associated interstitial lung disease (SSc-ILD). The autoinjector delivers a precise 162 mg dose of tocilizumab for easy subcutaneous administration, targeting interleukin-6 (IL-6) to reduce inflammation, joint pain, and swelling while preventing further damage. Buy Actemra Prefill Autoinjector to Treat Rheumatoid Arthritis and achieve relief from symptoms like joint stiffness and discomfort. Its tailored dosage schedule, based on patient weight and condition, ensures optimal results. Ordering Actemra from Canada provides access to high-quality, regulated medications at competitive prices, giving patients a convenient and reliable way to take control of their health and improve their overall well-being.

Product Overview

Actemra is a trusted treatment for various inflammatory conditions, including rheumatoid arthritis, juvenile idiopathic arthritis, giant cell arteritis, and systemic sclerosis-associated interstitial lung disease (SSc-ILD). This medication is also effective in managing cytokine release syndrome (CRS) caused by certain cancer treatments and is approved for use in severe COVID-19-related inflammation. Actemra is available as an autoinjector and in intravenous infusion forms, and it provides tailored solutions to meet diverse patient needs. With precise dosing options and proven efficacy, it helps reduce inflammation, alleviate symptoms, and prevent further joint or tissue damage.

The Actemra autoinjector delivers a 162 mg dose of tocilizumab in a convenient, easy-to-use device for subcutaneous administration. Patients with rheumatoid arthritis can benefit from this targeted therapy, which blocks interleukin-6 (IL-6), a key driver of inflammation. Actemra reduces joint pain, stiffness, and swelling while improving overall mobility. The recommended dosage for patients weighing under 100 kg is every other week, increasing to weekly if needed. For those weighing 100 kg or more, weekly administration is advised. Whether you’re dealing with active flare-ups or chronic symptoms, the Actemra autoinjector offers effective relief and improved quality of life.

Purchasing Actemra autoinjectors online from Canada provides access to high-quality, FDA-approved medications at competitive prices. With strict manufacturing standards and convenient delivery options, Canadian pharmacies ensure a seamless experience. Regular monitoring by healthcare providers ensures safe usage, whether managing rheumatoid arthritis or other inflammatory conditions. Actemra is also available in various strengths and forms to meet individualized treatment plans, making it a reliable choice for managing inflammation effectively. Buy Actemra Prefill autoinjector today and take a proactive step toward better health.

What Are the Uses of Actemra? 

  • Rheumatoid Arthritis (RA)
  • Juvenile Idiopathic Arthritis (JIA)
  • Giant Cell Arteritis (GCA)
  • Cytokine Release Syndrome (CRS)
  • Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)
  • COVID-19-related Severe Inflammation

What Are the Forms & Strengths of Actemra?

Actemra Prefilled Autoinjector is offered in different forms and strengths to suit various treatment needs and administration methods. Whether given as an intravenous (IV) infusion or a subcutaneous (SC) injection, each formulation is designed to deliver precise dosages for the effective management of specific conditions. Below are Actemra’s available forms and strengths.

Intravenous (IV) Infusion:

  • Single-Dose Vials: Actemra is supplied as a clear, colorless, pale yellow solution in single-dose vials for IV infusion. Each vial contains tocilizumab at a concentration of 20 mg per mL, available in the following volumes:
    • 80 mg/4 mL
    • 200 mg/10 mL
    • 400 mg/20 mL

Subcutaneous (SC) Injection:

  • Prefilled Syringes and Autoinjectors: Actemra is available in prefilled syringes and autoinjectors for subcutaneous administration. Each device delivers a 162 mg dose of tocilizumab in 0.9 mL of solution.

What Is the Recommended Dosage of Actemra?

The dosage of Actemra varies based on the condition being treated, the patient’s age, and the method of administration. Below is an overview of the recommended dosages:

For Rheumatoid Arthritis (RA)
    • Intravenous (IV) Infusion: 4 mg/kg every 4 weeks, which may be increased to 8 mg/kg based on the patient’s response.
  • Subcutaneous (SC) Injection:
    • For patients weighing <100 kg: 162 mg every other week, increasing to weekly if necessary.
    • For patients weighing ≥100 kg: 162 mg weekly.
For Juvenile Idiopathic Arthritis (JIA)
  • Systemic JIA (IV Infusion):
      • Patients weighing <30 kg: 12 mg/kg every 2 weeks.
      • Patients weighing ≥30 kg: 8 mg/kg every 2 weeks.
  • Polyarticular JIA (SC Injection):
    • Patients weighing <30 kg: 162 mg every 3 weeks.
    • Patients weighing ≥30 kg: 162 mg every 2 weeks.
For Giant Cell Arteritis (GCA)
  • Subcutaneous (SC) Injection: 162 mg once weekly, combined with a tapering course of glucocorticoids.
For Cytokine Release Syndrome (CRS)
  • IV Infusion:
    • Patients weighing <30 kg: 12 mg/kg per dose.
    • Patients weighing ≥30 kg: 8 mg/kg per dose.
    • Maximum of 4 doses, administered every 8 hours if needed.
For Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)
  • Subcutaneous (SC) Injection: 162 mg once weekly.
For COVID-19-related Severe Inflammation
  • IV Infusion: The maximum dose is 800 mg per infusion, and it is a single dose of 8 mg/kg. Additional doses may be considered but should be spaced at least 12 hours apart.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use Actemra?

Proper use of Actemra is essential to ensure its effectiveness while minimizing potential risks. Whether administered as an injection or through an IV infusion, following the correct procedures and guidance from your healthcare provider is crucial. Below are the key steps and considerations for using Actemra safely and effectively.

  • For Subcutaneous Injections:
    • Inject under the skin using a prefilled syringe or autoinjector.
    • Your doctor or nurse will demonstrate the proper injection technique.
    • Common injection sites include the abdomen or thighs. Avoid areas that are red, bruised, or tender.
    • Rotate injection sites to avoid irritation.
  • For Intravenous (IV) Infusions:
    • Actemra is administered through a vein by a healthcare professional.
    • Infusions usually take about an hour and are given every 4 weeks, depending on your condition.

Preparation:

  • Store Actemra in the refrigerator at 2°C–8°C (36°F–46°F).
  • Let the medication reach room temperature (up to 30 minutes) before injecting.
  • Do not shake the medication.

Regular Checkups:

  • Your doctor may require regular blood tests to monitor your liver, blood cell counts, and cholesterol levels during treatment.

 

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Actemra Work?

Actemra (tocilizumab) works by targeting a specific protein in the body called interleukin-6 (IL-6). IL-6 is a part of your immune system and plays a key role in causing inflammation. While inflammation is the body’s way of fighting infections or injuries, too much can lead to problems, especially in conditions like rheumatoid arthritis or cytokine release syndrome. Actemra blocks IL-6 from attaching to its receptors, which reduces the immune system’s overactive response. By doing this, Actemra helps lower inflammation, reduces symptoms like pain and swelling, and prevents further damage to tissues or joints. It helps calm the immune system without shutting it off completely, so your body can fight infections when needed.

Important Safety Information for Using Actemra

What Are the Side Effects of Actemra?

Common Side Effects of Actemra

Patients undergoing treatment may experience several common side effects ranging from mild to moderate. Awareness of these effects is vital for prompt management and ensuring therapy continuation without complications. Below is a detailed explanation of the typical side effects observed.

  • Upper Respiratory Tract Infections: Patients may experience symptoms such as nasal congestion, sore throat, and cough, similar to common cold or sinus infections. These infections occur because Actemra can suppress the immune system, making individuals more susceptible to pathogens affecting the upper respiratory tract. 
  • Headache: This is reported among Actemra users and can range from mild to severe. The exact cause is not fully understood, but it may be related to the body’s response to the medication or changes in blood pressure. Patients experiencing persistent or severe headaches should consult their healthcare provider. 
  • Hypertension (Increased Blood Pressure): Actemra has been associated with elevated blood pressure. Regular monitoring is essential, as unmanaged hypertension can lead to serious cardiovascular issues. If significant increases in blood pressure are observed, healthcare providers may need to adjust treatment plans or prescribe antihypertensive medications. 
  • Injection Site Reactions: Patients receiving subcutaneous injections of Actemra might experience localized reactions, including redness, swelling, pain, or itching at the injection site. These reactions are generally mild and resolve independently, but if they persist or worsen, medical advice should be sought. 
  • Elevated Liver Enzymes: Patients taking Actemra have been observed to have increased liver enzymes, such as alanine transaminase (ALT) and aspartate transaminase (AST). While often asymptomatic, significant elevations can indicate liver inflammation or damage. Regular liver function tests are recommended to monitor this potential side effect.

Serious Side Effects of Actemra

While Actemra (tocilizumab) effectively treats various inflammatory conditions, it is important to be aware of its potential serious side effects. These adverse reactions can significantly impact patient health and require immediate medical attention. Understanding these risks is crucial for patients and healthcare providers to ensure timely identification and management. Below is an overview of the serious side effects associated with Actemra.

  • Gastrointestinal Perforations: Actemra has been linked to the development of holes in the stomach or intestines, known as gastrointestinal perforations. This risk is higher in individuals with a history of diverticulitis or those concurrently using nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids. Symptoms include severe abdominal pain, fever, and changes in bowel habits. If these symptoms occur, immediate medical attention is necessary.
  • Elevated Liver Enzymes and Liver Damage: Treatment with Actemra can increase liver enzyme levels, indicating potential liver inflammation or damage. In severe cases, this may progress to serious liver conditions, including liver failure. Patients should undergo regular liver function tests, and any signs of liver issues—such as jaundice, dark urine, or persistent nausea—should be promptly reported to a healthcare provider.
  • Hematologic Abnormalities: Actemra may cause decreases in certain blood cell counts, including neutrophils (a type of white blood cell) and platelets. Low neutrophil counts (neutropenia) can increase susceptibility to infections, while low platelet counts (thrombocytopenia) can lead to bleeding and bruising. Regular blood monitoring is essential to detect these changes early.
  • Demyelinating Disorders: There have been reports of demyelinating disorders, such as multiple sclerosis, occurring in patients receiving Actemra. These conditions involve damage to the protective covering of nerves, leading to neurological symptoms like vision problems, muscle weakness, and impaired coordination. Patients should report any unusual neurological symptoms to their healthcare provider immediately. 

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Actemra? 

Before starting Actemra, it’s essential to understand the associated warnings to use the medication safely. These warnings address serious health risks, including hypersensitivity reactions, liver enzyme elevations, and reactivation of infections. Below is a comprehensive overview of the most critical warnings for patients and caregivers.

  • Serious Allergic Reactions: Severe hypersensitivity reactions, including anaphylaxis and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), have been reported during Actemra treatment. These reactions can occur with any infusion or injection, even if previous administrations were well-tolerated. Symptoms may include swelling of the face, lips, mouth, or tongue; trouble breathing; wheezing; severe itching; skin rash, hives, redness, or swelling outside of the injection site area; dizziness or fainting; fast heartbeat or pounding in the chest; and sweating. Patients should seek immediate medical attention if they experience any of these symptoms.
  • Hepatitis B Virus Reactivation: Actemra may cause the hepatitis B virus (HBV) to become active again in individuals who are chronic carriers. This reactivation can lead to serious liver problems or death. Healthcare providers should perform blood tests before starting treatment to check for HBV infection and monitor patients during therapy. Patients should inform their healthcare provider if they experience symptoms such as tiredness, skin or eyes looking yellow, little or no appetite, vomiting, clay-colored bowel movements, fevers, chills, stomach discomfort, muscle aches, dark urine, or skin rash.
  • Elevated Liver Enzymes: Treatment with Actemra has been associated with increases in liver enzymes, which can indicate liver damage. Regular monitoring of liver function tests is recommended. If significant elevations occur, dosage adjustments or discontinuation of therapy may be necessary.
  • Risk of Certain Cancers: Actemra may increase the risk of certain cancers by affecting the immune system. Before starting treatment, patients should discuss their risk factors with their healthcare provider.

What Are the FDA Boxed Warning for Actemra?

Actemra carries an FDA-boxed warning due to the increased risk of serious infections that may lead to hospitalization or death. These infections include active tuberculosis, invasive fungal infections, and infections caused by opportunistic pathogens. Patients should be tested for latent tuberculosis before starting Actemra (except in COVID-19 patients) and monitored for signs of infection during and after treatment. If a serious infection develops, Actemra should be interrupted until the infection is controlled. 

What Are the Actemra Precautions?

When considering treatment with Actemra, it’s essential to be aware of several important precautions to ensure safe and effective use:

  • Risk of Serious Infections: Actemra can increase the risk of serious infections, including tuberculosis (TB), bacterial, invasive fungal, viral, or other opportunistic infections. Patients should be tested for latent TB before starting Actemra (except in COVID-19 patients) and monitored for signs of infection during and after treatment. If a serious infection develops, Actemra should be interrupted until the infection is controlled.
  • Gastrointestinal Perforations: Events of gastrointestinal (GI) perforation have been reported primarily as complications of diverticulitis. Actemra should be used with caution in patients at increased risk for GI perforation. To identify GI perforation early, promptly evaluate patients presenting with fever, new-onset abdominal symptoms, and a change in bowel habits.
  • Hepatotoxicity: Serious cases of liver injury have been observed, some resulting in liver transplant or death. Monitor liver function tests before and during treatment. It is not recommended to initiate Actemra in patients with elevated liver enzymes (ALT or AST >1.5x ULN). If elevations greater than 5x ULN occur, discontinue Actemra.
  • Laboratory Monitoring: Blood tests should be regularly monitored due to potential changes in neutrophil, platelet, liver enzyme, and lipid levels. Based on these results, therapy adjustments may be necessary.
  • Hypersensitivity Reactions: Serious allergic reactions, including anaphylaxis, have been reported. These can occur with any infusion or injection, even if they did not occur with earlier administrations. Stop Actemra and seek emergency help immediately if a serious allergic reaction occurs.
  • Demyelinating Disorders: Caution is advised when prescribing Actemra to patients with preexisting or recent-onset demyelinating disorders, as it may exacerbate these conditions. Monitor patients for signs and symptoms potentially indicative of demyelinating disorders.
  • Vaccinations: Live vaccines should not be used concurrently with Actemra, as clinical safety has not been established. Patients should be brought up to date with all immunizations prior to initiating Actemra therapy.
  • Malignancies: The impact of Actemra on the development of malignancies is unknown, but clinical studies have observed them. Actemra is an immunosuppressant, and treatment with immunosuppressants may increase the risk of malignancies. 

What Are the Contraindications of Actemra?

Not everyone is a suitable candidate for Actemra treatment. Understanding its contraindications is vital to ensuring the drug’s safety and effectiveness. These contraindications highlight specific conditions and health concerns where Actemra should be avoided to protect patient well-being. Below is an overview of the most critical considerations.

  • Actemra is contraindicated in patients with known hypersensitivity to the drug. 
  • Additionally, live vaccines concurrently with Actemra are not recommended, as clinical safety has not been established. 
  • Patients with active hepatic disease or hepatic impairment should not be treated with Actemra. 
  • Furthermore, Actemra is not recommended in patients with an absolute neutrophil count (ANC) less than 1000 per mm³, platelet count below 50,000 per mm³, or elevated ALT or AST above 10 times the upper limit of the reference range.

What If You Miss a Dose of Actemra?

If you miss a dose of Actemra, the appropriate action depends on your dosing schedule:

  • For Weekly Injections:
    • If you remember the missed dose within 7 days of the scheduled injection, skip the missed dose and continue with your next injection on the regularly scheduled day. Do not administer two injections to make up for the missed one.
  • For Biweekly (Every Two Weeks) Injections:
    • If you recall the missed dose within 7 days of the scheduled injection, administer it as soon as possible. Then, proceed with your next injection on the originally scheduled day.
  • For Intravenous (IV) Infusions:
    • If you miss a scheduled infusion, contact your healthcare provider promptly to reschedule. They will provide guidance on when to receive your next dose.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Actemra?

If you or someone else has taken too much Actemra, seeking immediate medical attention is important. Overdosing on Actemra can lead to serious health complications, including severe infections, liver damage, and gastrointestinal perforation. Symptoms of an overdose may include fever, chills, nausea, vomiting, abdominal pain, and jaundice. In severe cases, an overdose can be fatal. If you suspect an overdose, call 911 or your local emergency number immediately. Do not wait for symptoms to appear before seeking help. Prompt medical attention can be life-saving.

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How to Store Actemra?

Proper storage is a must to maintain the potency and reliability of Actemra. Incorrect handling or storage can compromise its effectiveness. Knowing the right storage practices ensures the medication remains safe and ready for use, whether it’s a prefilled syringe or an infusion. Here are the key storage recommendations.

  • For Subcutaneous Injection (Prefilled Syringes or Autoinjectors):
    • Store in the refrigerator at 2°C to 8°C (36°F to 46°F).
    • Keep the medication in its original packaging to protect it from light.
    • Do not freeze the medication.
    • If necessary, Actemra prefilled syringes and autoinjectors can be stored at room temperature (up to 30°C or 86°F) for up to 2 weeks (14 days). Once removed from the refrigerator, they should not be returned. If not used within this period, dispose of them appropriately.
  • For Intravenous (IV) Infusion:
    • Diluted Solution: After dilution, the Actemra infusion solution can be stored at 2°C to 8°C (36°F to 46°F) or at room temperature (up to 30°C or 86°F). The specific storage duration post-dilution should be confirmed by a healthcare provider or pharmacist.
  • General Precautions:
    • Do Not Shake: Avoid shaking the medication, which can affect its potency.
    • Inspect Before Use: Check the solution for particulate matter or discoloration before administration. Do not use it if it appears cloudy, discolored or contains particles.
    • Keep Out of Reach of Children: Ensure that Actemra is stored securely and out of the reach of children.

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Actemra?

Actemra interacts with various medications, potentially altering their effects or increasing the risk of adverse reactions. Below is an explanation of each interaction:

  • Immunosuppressants and Biologic Agents: Combining Actemra with other immunosuppressive drugs or biologic disease-modifying antirheumatic drugs (DMARDs) can significantly increase the risk of infections. Both Actemra and these agents suppress the immune system, and their combined effect can lead to a heightened susceptibility to infections. Therefore, concurrent use is generally avoided to minimize this risk.
  • CYP450 Substrates: Actemra may influence the activity of cytochrome P450 enzymes, affecting drugs metabolized by these pathways. By inhibiting interleukin-6 (IL-6) signaling, Actemra can restore CYP450 enzyme activity to higher levels, leading to increased metabolism of drugs that are CYP450 substrates. This can reduce the effectiveness of certain medications, such as:
  • Statins: e.g., atorvastatin, lovastatin, simvastatin. Actemra can increase the metabolism of these drugs, potentially reducing their cholesterol-lowering effects.
  • Oral Contraceptives: e.g., ethinyl estradiol combinations. The increased metabolism may decrease the efficacy of birth control pills, raising the risk of unintended pregnancy.
  • Proton Pump Inhibitors: e.g., omeprazole. Actemra can enhance the breakdown of these drugs, potentially diminishing their effectiveness in reducing stomach acid.
  • Anticoagulants: e.g., warfarin. Increased metabolism may reduce the anticoagulant effect, necessitating close monitoring of blood clotting parameters.
  • Immunosuppressants: e.g., cyclosporine, sirolimus. Actemra can increase the metabolism of these drugs, potentially reducing their immunosuppressive effects, which may require dosage adjustments.
  • Others: e.g., theophylline, dextromethorphan. The accelerated metabolism of these drugs can lead to decreased therapeutic effects, necessitating monitoring and possible dosage modifications. 

What Are the Other Actemra Interactions?

Beyond its role in managing certain conditions, Actemra (tocilizumab) can influence various health factors, from infection risks to organ function. Being informed about these potential interactions and associated health precautions is key to minimizing complications and ensuring the best outcomes during therapy.

  • Infections: Actemra can increase the risk of infections or worsen existing ones. Patients should be monitored for signs of infection during treatment. 
  • Tuberculosis: There’s a heightened risk of reactivating latent tuberculosis. Screening for tuberculosis is recommended before initiating therapy. 
  • Demyelinating Disorders: Caution is advised when prescribing Actemra to patients with preexisting or recent-onset demyelinating disorders, as it may exacerbate these conditions. 
  • Gastrointestinal Perforation: Rare cases of gastrointestinal perforation have been reported, especially in patients with a history of diverticulitis or those on concurrent nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids. 
  • Lipid Abnormalities: Elevations in lipid parameters, including total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL), have been observed. Regular lipid monitoring is recommended. 
  • Liver Dysfunction: Patients receiving Actemra have had elevated liver enzymes. Monitoring liver function tests is advised, and caution should be exercised in patients with hepatic impairment. 
  • Neutropenia/Thrombocytopenia: Decreases in neutrophil and platelet counts have been noted. Complete blood counts should be monitored during therapy. 
  • Renal Impairment: While specific studies are limited, patients with renal impairment should be closely monitored, as renal function may influence drug clearance. 
  • Alcohol: There is one noted alcohol/food interaction with Actemra. Patients should consult their healthcare provider regarding alcohol consumption during treatment. 

[Note: This isn’t a complete list, and there could be other drugs that interact with Actemra. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Actemra Alternatives?

Actemra is a powerful medication, but it might not work for everyone due to varying responses or contraindications. Thankfully, numerous alternatives target similar conditions and offer tailored solutions. Here’s a detailed list of Actemra alternatives with their generic names to consider discussing with your doctor.

  • Humira (adalimumab)
  • Enbrel (etanercept)
  • Remicade (infliximab)
  • Cimzia (certolizumab pegol)
  • Simponi (golimumab)
  • Orencia (abatacept)
  • Xeljanz (tofacitinib)
  • Olumiant (baricitinib)
  • Rinvoq (upadacitinib)
  • Kevzara (sarilumab)
  • Kineret (anakinra)
  • Taltz (ixekizumab)
  • Cosentyx (secukinumab)
  • Stelara (ustekinumab)
  • Imuran (azathioprine)
  • Methotrexate (methotrexate)
  • Arava (leflunomide)
  • Plaquenil (hydroxychloroquine)
  • Cytoxan (cyclophosphamide)
  • CellCept (mycophenolate mofetil)
  • Benlysta (belimumab)
  • Rituxan (rituximab)
  • Zeposia (ozanimod)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Actemra Cost & Coupons

Actemra is a trusted medication for managing rheumatoid arthritis and other inflammatory conditions, but its high cost in the USA can create a significant financial burden for many individuals. At Polar Bear Meds, we are committed to providing quality medications at more affordable prices. With competitive pricing and additional savings options, such as discount coupons, we make accessing the treatment you need easier. If you’re looking for a cost-effective solution, buy Actemra Prefill Autoinjector online and enjoy top-quality medication at a lower cost. To make your purchase even more affordable, buy Actemra Prefill Autoinjector at coupon offer using the code “WELCOMEPB10” at checkout to receive 10% off your first order. This exclusive offer allows you to manage your treatment for rheumatoid arthritis without breaking the bank while ensuring you receive authentic and effective medication from a trusted source. Take advantage of this special deal today and save on your essential medication. Buy Actemra Prefill Autoinjector online and enjoy the convenience of affordable, reliable healthcare solutions delivered right to your doorstep.

Frequently Asked Questions

How long does it take for Actemra to start working?

The time it takes for Actemra to show noticeable results varies from person to person. Some patients may experience symptom relief within a few weeks, while others may take several months to improve significantly. It’s important to continue the treatment as prescribed and attend regular checkups to monitor progress.

Can Actemra increase the risk of infections?

Yes, Actemra suppresses certain immune responses, which can increase the risk of infections, including serious ones like tuberculosis, bacterial infections, or fungal infections. It is important to monitor for signs of infection, such as fever, cough, or fatigue, and report them to your doctor immediately. Patients are usually screened for tuberculosis before starting treatment.

Can Actemra be stopped abruptly?

It is not recommended that Actemra be stopped abruptly without consulting your healthcare provider. Stopping suddenly may cause a flare-up of your condition or worsen symptoms. If you need to discontinue the medication, your doctor will guide you on how to do so safely and monitor your condition during the process.

Can Actemra cause hair loss?

Hair loss is not a commonly reported side effect of Actemra. However, autoimmune conditions like rheumatoid arthritis, which Actemra treats, can sometimes cause hair thinning or loss. If you notice hair loss during treatment, consult your healthcare provider to determine the underlying cause and discuss potential solutions.

Can I get vaccinated while on Actemra?

Live vaccines should be avoided while taking Actemra, as the medication suppresses the immune system and can reduce the effectiveness of vaccines or increase the risk of infection. Non-live vaccines may be safe but should be discussed with your healthcare provider, who can determine your appropriate vaccination schedule.

Is Actemra safe for long-term use?

Actemra can be used long-term under close medical supervision, especially for chronic conditions like rheumatoid arthritis or juvenile idiopathic arthritis. However, monitoring liver function, blood counts, and cholesterol levels is essential to detect and manage any potential long-term side effects. Discuss risks and benefits with your doctor.

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IMPORTANT NOTICE : The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

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