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Erenumab-aooe

Aimovig Pre-Filled Autoinjector

Aimovig (erenumab-aooe) is a prescription medication used to prevent migraines. It belongs to a class of drugs called CGRP inhibitors, which work by blocking a protein that contributes to migraine attacks. Available in prefilled autoinjectors and syringes, Aimovig is taken as a monthly subcutaneous injection. It comes in two strengths: 70 mg/mL and 140 mg/mL. While effective in reducing migraine frequency, it may cause side effects such as injection site reactions, muscle cramps, and constipation. Aimovig is generally well tolerated and is an option for individuals who haven’t responded to other treatments.

Product Overview

Aimovig (erenumab-aooe) is a monoclonal antibody medication designed to prevent migraines by blocking the calcitonin gene-related peptide (CGRP) receptor, a protein involved in migraine attacks. Unlike traditional migraine treatments, Aimovig targets a single protein, reducing the likelihood of drug interactions. It is available in prefilled autoinjectors and syringes, with two dosage options: 70 mg/mL and 140 mg/mL. 

Patients self-administer Aimovig as a monthly subcutaneous injection, making it a convenient option for migraine prevention. Common side effects include injection site reactions, muscle cramps, and constipation. Some individuals may experience new or worsened high blood pressure, requiring monitoring by a healthcare provider. Aimovig is not intended for acute migraine treatment but serves as a long-term preventive therapy. 

It may be a suitable option for those who have not found relief with other migraine medications. Patients should consult their doctor to determine if Aimovig aligns with their health needs and migraine management plan. Proper storage and adherence to the injection schedule are crucial for effectiveness.

What Is Aimovig Autoinjector Used For?

    • FDA-Approved Use: Aimovig is approved by the FDA to treat and prevent migraines.
  • Off-Label Uses (Not FDA-Approved but Sometimes Prescribed):
    • Cluster headaches: A type of severe headache that occurs in cycles.
    • Vestibular headaches: Migraines that cause dizziness and balance issues.

What Strengths Does Aimovig Come In?

Aimovig comes as a solution inside pre-filled autoinjector pens and pre-filled syringes. You can inject it yourself at home once a month. Its available strengths are:

  • 70 mg/mL
  • 140 mg/mL

Aimovig is injected under the skin (subcutaneous injection). Each autoinjector or syringe is for one-time use only—it must be discarded after use.

What Is the Typical Dosage of Aimovig?

The dosage of Aimovig depends on several factors, including the severity of your migraines and how your body responds to the medication. Your doctor will usually start with a lower dose and adjust it if needed to find the right balance between effectiveness and minimal side effects.

The goal is to use the smallest dose that works well for you while keeping side effects under control. Below is a general guideline on commonly recommended dosages, but your doctor will determine the best dosage based on your individual needs. Always follow your doctor’s instructions carefully to get the best results from Aimovig.

Dosage for Migraine
  • Available Doses:
    • Aimovig is prescribed in two dosage options: 70 mg or 140 mg.
    • It is taken once per month.
  • Starting Dose: Most patients begin with a 70 mg dose per month.
  • Adjusting the Dose: If 70 mg does not reduce the number of migraine days enough, your doctor may increase the dose to 140 mg per month.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use Aimovig?

If you’re prescribed Aimovig, it’s important to use it correctly to get the best results. Here’s a simple guide on how to take Aimovig safely and effectively.

  • Instructions on Taking Aimovig:
      • Aimovig is a monthly injection that you give yourself under the skin (subcutaneous injection).
      • Your healthcare provider will show you how to inject it the first time, so you feel confident doing it on your own.
      • Aimovig comes in single-use autoinjectors and prefilled syringes, each containing just one dose. After using it, dispose of the injector or syringe properly.
  • How to Inject Aimovig:
      • If you’re using an autoinjector, check the manufacturer’s website for step-by-step instructions and videos on how to use it.
      • If you’re using a prefilled syringe, your doctor or pharmacist can guide you on how to inject it safely.
  • When to Take Aimovig:
    • Take it once a month, at any time of the day.
    • If you miss a dose, take it as soon as you remember. Your next dose should be one month after the missed dose to stay on track. Using a reminder app or setting an alarm can help you remember.
  • Taking Aimovig with Food: You can take Aimovig with or without food—it won’t affect how the medication works.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Aimovig Work?

Aimovig is a drug called a monoclonal antibody. This kind of drug is made in a lab from immune system proteins. Aimovig works by stopping the activity of a protein in your body called calcitonin gene-related peptide (CGRP). CGRP can cause inflammation and vasodilation (widening of blood vessels) in your brain. The inflammation and vasodilation brought on by CGRP is a possible cause of migraine headaches. In fact, when a migraine headache is starting to occur, people have higher levels of CGRP in their bloodstream. Aimovig helps prevent migraine by stopping the activity of CGRP.

While most medications work by affecting many substances in your body, monoclonal antibodies such as Aimovig work on only one protein in the body. Because of this, Aimovig may cause fewer drug interactions and side effects. This can make it a good treatment option for people who can’t take other medications due to side effects or interactions. Aimovig may also be a good treatment option for people who haven’t found another medication that can reduce their migraine days enough.

What Are the Important Safety Information for Using Aimovig?

What Are the Side Effects of Aimovig?

Aimovig can cause mild or serious side effects. The following list contains some of the key side effects that may occur while taking Aimovig. This list does not include all possible side effects.

For more information on the possible side effects of Aimovig, or tips on how to deal with a troubling side effect, talk with your doctor or pharmacist.

Common Side Effects of Aimovig

Like any medication, Aimovig may cause some side effects, but they are usually mild and temporary. Most people experience them for just a few days to weeks as their body adjusts. However, if these side effects persist, worsen, or become bothersome, be sure to check with your doctor or pharmacist. Here are some common side effects you might notice:

  • Injection Site Reactions: Some people may experience redness, itching, or mild pain where the injection was given. The skin may also darken slightly. This should improve on its own, but if it gets worse, let your doctor know.
  • Muscle Cramps: You might feel a sudden tightening or discomfort in your muscles, which can be uncomfortable but usually passes quickly. Staying hydrated and stretching may help.
  • Muscle Spasms: Some people experience involuntary muscle movements or twitching, which can feel strange but is usually harmless. If it becomes frequent or painful, reach out to your doctor.

If any of these persist or worsen, don’t hesitate to speak with your healthcare provider.

Serious Side Effects of Aimovig

While Aimovig is generally well-tolerated, in rare cases, it may cause serious side effects. If you notice any of the following symptoms, contact your doctor immediately. If the reaction seems severe or life-threatening, call 911 or seek emergency medical help right away. Here are some serious side effects to watch for:

  • High Blood Pressure (or Worsening of Existing High Blood Pressure): Aimovig may cause a sudden rise in blood pressure, which can lead to frequent headaches, dizziness, or even nosebleeds. If you notice these symptoms, get your blood pressure checked and talk to your doctor.
  • Severe Constipation: Some people may experience difficulty passing stools, which can become painful and uncomfortable. If you haven’t had a bowel movement for several days or feel persistent stomach discomfort, seek medical advice.
  • Allergic Reactions: Although rare, some people might have an allergic reaction to Aimovig. Signs include itching, swelling (especially of the face, lips, or throat), trouble breathing, or severe dizziness. If you experience these symptoms, get medical help right away.

If anything feels unusual or concerning, always check in with your doctor as soon as possible.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Aimovig?

Before using Aimovig, it’s essential to be aware of certain warnings to ensure safe and effective use. Here are some key points to keep in mind:

  • Allergic Reactions: Aimovig may cause allergic reactions, which can sometimes be severe. If you experience signs of a serious allergic reaction, such as swelling, trouble breathing, or severe itching, stop using the medication immediately and seek emergency medical help. These reactions can happen within hours or even up to a week after your injection.
  • Constipation Risks: Some people taking Aimovig experience constipation, which in rare cases can lead to serious complications. If you notice severe or persistent constipation, inform your doctor as soon as possible.
  • Blood Pressure Changes: Aimovig may cause high blood pressure or worsen existing high blood pressure. It’s important to monitor your blood pressure regularly while taking this medication. If you notice any unusual symptoms such as headaches, dizziness, or nosebleeds, contact your doctor.
  • Double-Check Your Medication: Always check the label on your prefilled autoinjector or syringe before injecting to ensure you have the correct medication and dosage. Using the wrong medication by mistake can be dangerous.
  • Not for Treating Active Migraines: Aimovig is only for preventing migraines—it does not work to stop a migraine that has already started. If you need treatment for an active migraine, talk to your doctor about alternative medications that can provide relief.

What Are the Aimovig Precautions?

Before starting Aimovig, it’s important to talk to your doctor about your medical history. This medication may not be suitable for everyone, especially if you have certain health conditions. Here are some key precautions to consider:

  • Aimovig may increase blood pressure or make existing high blood pressure worse. If you already have high blood pressure, discuss the risks with your doctor before starting this medication. If your blood pressure rises while taking Aimovig, your doctor may recommend stopping it.
  • The Aimovig autoinjector and syringe contain a type of rubber similar to latex. If you have a severe latex allergy, this could trigger a reaction. If you have had strong allergic reactions to latex before, Aimovig may not be the best option for you.
  • If you’ve ever had an allergic reaction to Aimovig or any of its ingredients, you should not take this medication. Talk to your doctor about alternative treatments that might be safer for you.
  • If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor whether Aimovig is safe for you and your baby. Your doctor can help you weigh the benefits and risks before making a decision.

What Are the Contraindications of Aimovig?

You should not use Aimovig if you have a known allergy to the medication or any of its ingredients. If you have had an allergic reaction to Aimovig in the past, talk to your doctor about alternative treatment options.

What If You Miss a Dose of Aimovig?

If you miss a dose, take it as soon as you remember. Then, schedule your next dose one month after the missed one. Mark the new date so you can stay on track with your treatment. If you’re unsure about when to take your next dose, talk to your doctor or pharmacist for guidance.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Aimovig?

Taking more than the recommended dose of Aimovig can increase your risk of side effects, especially reactions at the injection site. If you are allergic to Aimovig or latex (which is found in Aimovig’s packaging), you may have a more serious reaction. Possible signs of an overdose include:

  • Severe pain, itching, redness, or skin darkening at the injection site.
  • Flushing, a warm sensation with redness or a darker skin tone.
  • Hives, which are itchy, raised bumps on the skin.
  • Swelling under the skin (angioedema) that can be painful or uncomfortable.
  • Swelling of the tongue, throat, or mouth, which may make it hard to breathe.
  • Trouble breathing, which could be serious and need urgent medical attention.

If you think you’ve taken too much Aimovig, call your doctor or the Poison Control Center at 800-222-1222 for advice. If you have severe or life-threatening symptoms, call 911 or go to the nearest emergency room right away.

[Note: If you consumed more than the recommended dose, get medical help right away, or call the Poison Help line at 1-800-222-1222.]

How to Store Aimovig?

Proper storage of Aimovig is important to ensure it remains safe and effective. Here’s what you need to know:

  • Refrigeration: Keep Aimovig in the refrigerator at a temperature of 36°F to 46°F (2°C to 8°C).
  • Room Temperature: If needed, Aimovig can be taken out of the refrigerator and stored at room temperature (68°F to 77°F or 20°C to 25°C). However, once it is at room temperature, it must be used within 7 days.
  • Do Not Re-Refrigerate: Once Aimovig has been removed from the fridge and warmed to room temperature, do not put it back in the refrigerator.
  • Do Not Freeze or Shake: Never freeze or shake Aimovig, as this can damage the medication.
  • Keep It in Its Original Packaging: Always store Aimovig in its original package to protect it from light.
  • Expired Medication: If Aimovig has expired or you are unsure if it is still safe to use, talk to your pharmacist for guidance.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Aimovig?

Most medications have some potential for drug interactions, which can either weaken their effect or increase the risk of side effects. However, Aimovig generally does not have drug interactions. This is because of the way it is processed in the body.

  • How Aimovig is Processed in the Body: Many drugs, vitamins, and supplements are broken down by enzymes in the liver. However, Aimovig is different. It belongs to a class of drugs called monoclonal antibodies, which are not processed by the liver. Instead, these drugs are broken down inside other cells in the body. Because of this, Aimovig does not typically interact with other medications in the same way that liver-processed drugs do.
  • Should You Still Check for Drug Interactions?: Even though Aimovig doesn’t usually interact with other medications, it’s still important to talk to your doctor or pharmacist before starting Aimovig. Let them know about all the prescription and over-the-counter medications you take, including herbs, vitamins, and supplements. If you have any concerns about whether Aimovig is safe to take with your current medications, your doctor can help you make the best decision for your treatment plan.

What Are the Other Aimovig Interactions?

  • Alcohol and Aimovig: There is no known interaction between Aimovig and alcohol. However, if you find that drinking alcohol triggers your migraines, it’s best to avoid it while using Aimovig. Even small amounts of alcohol can make migraines more frequent or more painful for some people. If alcohol affects your migraines, sticking to alcohol-free options may help you get the best results from your treatment.
  • Aimovig and Supplements: Before taking Aimovig, let your doctor or pharmacist know about any herbs, vitamins, or supplements you use. This can help you avoid any unexpected interactions. If you have any concerns, always check with your doctor or pharmacist before adding new supplements to your routine.
    • Aimovig with Herbs and Vitamins: So far, there are no known interactions between Aimovig and herbs or vitamins. However, since new information about drug interactions can emerge, it’s still important to consult your doctor before taking any additional supplements while using Aimovig.
  • Aimovig and Food: There are no reported interactions between Aimovig and specific foods. If you have any dietary concerns while taking Aimovig, talk to your doctor to see if any adjustments are needed.
  • Aimovig and Vaccines or Lab Tests: Aimovig does not interfere with vaccines or lab tests. If you need to get vaccinated or undergo lab tests while taking Aimovig, there should be no issues. However, if you have any concerns, consult your doctor for guidance.

If you have any questions about interactions with Aimovig, speak with your doctor or pharmacist to make sure you’re using the medication.

[Note: This isn’t a complete list, and there could be other drugs that interact with Aimovig. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Aimovig Alternatives?

If Aimovig isn’t working well for you or if you’re looking for other options to prevent migraine headaches, there are several alternative medications available. Some treatments may be more effective for you based on your specific migraine symptoms and medical history. Your doctor can help you find a better fit by discussing other FDA-approved migraine prevention medications. There are also some treatments that, while not specifically approved for migraines, are commonly prescribed off-label to help reduce migraine frequency. If you’re considering a switch, talk to your doctor to explore the best alternatives for you.

FDA-Approved Alternatives for Preventing Migraine Headaches

If you’re looking for alternatives to Aimovig, there are other FDA-approved medications that help prevent migraine headaches. These include:

    • CGRP Antagonists (Similar to Aimovig): These medications work by blocking a protein involved in migraine attacks:
      • Vyepti (eptinezumab)
      • Ajovy (fremanezumab-vrfm)
      • Emgality (galcanezumab-gnlm)
    • Seizure Medications Used for Migraine Prevention: Some anti-seizure drugs are effective in reducing migraine frequency:
      • Topamax (topiramate)
      • Depakote (divalproex sodium)
      • Trokendi XR (topiramate)
  • Other FDA-Approved Options
    • Propranolol (Inderal, Inderal LA) – A beta-blocker that helps prevent migraines
    • Botox (onabotulinumtoxinA) – Used for chronic migraines
Off-Label Medications for Migraine Prevention

Some drugs are not specifically FDA-approved for migraines but are often prescribed:

  • Seizure Medications: Valproate sodium
  • Antidepressants: Amitriptyline, Venlafaxine (Effexor XR)
  • Beta-Blockers: Atenolol (Tenormin), Metoprolol (Toprol XL, Lopressor)

If you’re considering switching medications, talk to your doctor to find the best option for you.

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Aimovig Cost & Coupons

Managing migraines with Aimovig can be costly in the U.S., with prices reaching thousands of dollars per month without insurance. Polar Bear Meds offers a budget-friendly alternative—buy Aimovig online from Canada at a substantially lower price. As a first-time customer, you can save 10% using our Aimovig coupon code “WELCOMEPB10” at checkout. Plus, with our referral program, you can save up to $200 on future purchases. Don’t overpay for essential migraine relief—choose Polar Bear Meds for affordable, high-quality Aimovig and cut your medication costs significantly.

Frequently Asked Questions

Will I need to use Aimovig long term?

If Aimovig helps reduce your migraine headaches, your doctor may recommend continuing it as a long-term treatment. Since migraines are a chronic condition, many people use Aimovig for an extended period to help manage their symptoms. However, your doctor will monitor your progress and decide if you need to stay on it long-term.

Why does Aimovig cause hair loss?

Hair loss was not reported as a side effect in clinical trials of Aimovig. However, some people have reported hair loss after the drug was approved. Because these reports weren’t part of controlled studies, it’s unclear whether Aimovig was the cause or if other factors played a role. If you experience hair loss while taking Aimovig, talk to your doctor.

How long does Aimovig take to work?

Aimovig doesn’t work immediately. It may take a few weeks to start reducing migraine days, and full effects can take several months. In clinical trials, many people noticed fewer migraine days within the first month and continued to see improvement over time with ongoing treatment. If you’re not seeing results right away, stick with it and talk to your doctor if you have concerns.

Does stopping Aimovig cause withdrawal symptoms?

There haven’t been any reports of withdrawal symptoms after stopping Aimovig. However, since Aimovig was only approved in 2018, there is limited data on long-term use and discontinuation. If you stop using Aimovig, your migraines may return to how they were before treatment, but you shouldn’t experience withdrawal effects. If you’re considering stopping Aimovig, talk to your doctor about the best approach.

Can you use Aimovig to treat a migraine headache?

No, Aimovig is only for migraine prevention. It works by reducing how often migraines occur, but it won’t stop a migraine once it has started. If you need relief during a migraine attack, your doctor may recommend a different medication to use when symptoms appear.

Is Aimovig a biologic?

Yes, Aimovig is a biologic medication, specifically a monoclonal antibody. Unlike traditional medications made from chemicals, biologics are developed from natural sources like proteins or cells. Aimovig targets a specific protein linked to migraines, which may lead to fewer side effects compared to traditional migraine treatments that affect multiple systems in the body.

How is Aimovig different from other migraine drugs?

Aimovig stands out because it was the first FDA-approved medication specifically designed to prevent migraines. Unlike other migraine prevention drugs, which were originally made to treat conditions like high blood pressure, depression, or seizures, Aimovig was created just for migraines.

It belongs to a new class of drugs called CGRP antagonists, which work by blocking a protein linked to migraine attacks. Many older migraine prevention drugs were not designed for this purpose and are often used off-label.

Another key difference is that Aimovig is a once-monthly injection that you can self-administer at home. Most other migraine prevention medications come in pill form and must be taken daily. Botox is another injectable migraine treatment, but it requires multiple injections at a doctor’s office every three months.

Aimovig is also a monoclonal antibody, meaning it’s made from immune system cells in a lab. Unlike traditional migraine medications, which are broken down by the liver, monoclonal antibodies break down in different cells throughout the body. This may result in fewer drug interactions compared to other migraine prevention options.

Does Aimovig cure migraine?

No, Aimovig does not cure migraines. Currently, there is no cure for migraines, but Aimovig can help reduce the frequency and severity of migraine attacks. If you’re considering Aimovig, talk to your doctor to see if it’s the right option for you.

If I take Aimovig, can I stop taking my other preventive medications?

Maybe. Everyone responds to Aimovig differently. If Aimovig works well for you and reduces your migraine attacks, you might be able to stop or lower the dose of other preventive medications.

However, when you first start Aimovig, your doctor will likely have you continue your other migraine prevention medications. This helps ensure that you don’t experience more migraines while adjusting to Aimovig.

After about 2 to 3 months, your doctor will evaluate how well Aimovig is working for you. If it’s helping, you and your doctor can discuss whether to stop or reduce your other migraine medications. Always follow your doctor’s guidance before making any changes to your medication routine.

Does Aimovig cause weight gain?

No, weight gain is not a known side effect of Aimovig. In clinical studies, people taking Aimovig did not report significant weight gain or loss. However, weight changes are common in people who experience migraines, but this is usually due to the migraines themselves, not Aimovig. Some people lose weight because migraines can cause nausea, vomiting, or loss of appetite. If you notice any unusual weight changes while taking Aimovig, talk to your doctor to rule out other possible causes.

Are Aimovig and Emgality the same?

Not exactly. Both Aimovig and Emgality help prevent migraines, but they contain different active ingredients.

  • Aimovig (made by Amgen) contains erenumab-aooe.
  • Emgality (made by Eli Lilly) contains galcanezumab-gnlm.

Even though they use different active ingredients, both medications work by blocking the CGRP pathway, which plays a role in migraine attacks. Your doctor can help decide which one is better for you, based on how your body responds to treatment.

Where is the best place to inject Aimovig?

You should only inject Aimovig into certain areas of your body. The best injection sites include:

  • Thigh
  • Stomach (abdomen) – but avoid the 2-inch area around your belly button
  • Outer upper arm – but only if someone else is giving you the injection

Rotate the injection site each time to avoid irritation. If you have questions about self-injecting, your doctor or pharmacist can help guide you.

How quickly does Aimovig start working?

Aimovig can start reducing migraine frequency within about 3 months. Some people notice improvements sooner, but results vary for everyone. Your body may need time to adjust, so be patient and continue taking Aimovig as prescribed. If you don’t see results after a few months, talk to your doctor about adjusting your treatment plan.

What not to take with Aimovig?

Aimovig does not have any major drug interactions. Unlike some other migraine medications, it doesn’t interfere with most commonly used drugs. There are no known food interactions with Aimovig. You don’t need to follow any special diet while taking it. However, certain foods can trigger migraines, such as caffeine, alcohol, processed meats, or artificial sweeteners.

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IMPORTANT NOTICE : The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

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