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Almotriptan

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Product Details

Description

Buy Almotriptan Online from Licensed Canadian Pharmacies

Almotriptan, known by the brand name Axert, is a medication that treats migraine attacks once they begin. It helps relieve head pain and migraine symptoms like nausea, light sensitivity, and sound sensitivity.

Almotriptan is meant for adults and teens who have been diagnosed with migraines. It’s not designed to stop future attacks or to treat other headache types, such as cluster or tension headaches.

Blood vessels in the brain widen, and nerve signals trigger intense pain during a migraine attack. Almotriptan works by targeting serotonin receptors (5-HT1B/1D) in the brain to narrow those vessels and calm pain pathways, providing fast relief.

This medicine should be taken as soon as migraine pain starts, not before. Most people find that one tablet helps relieve their migraine within a few hours. If the pain returns, your health care provider may allow a second dose after at least two hours, but you can never take more than 2 tablets of Almotriptan 12.5 mg in a day.

Generic NameAlmotriptan (Pronunciation: AL-moe-TRIP-tan)
Brand NameAxert
FormsOral Tablets
Strengths Available6.25 mg, 12.5 mg
Packaging6 tablets per pack
Requires PrescriptionPrescription only (Rx)
Ships to the U.S.Yes
Uses and Benefits

What Are the Uses of Almotriptan?

Almotriptan is approved for the acute treatment of migraine attacks that occur with or without aura in adults and adolescents who are 12 to 17 years of age.

Note: In teens, Almotriptan can help with headache pain. It hasn’t been shown to help nausea or sensitivity to light or sound in this age group.

Benefits of Almotriptan

  • Rapid relief: Can ease headache pain and migraine symptoms (nausea, sensitivity to light/sound) once the attack begins.
  • Functional recovery: When migraine symptoms are relieved, patients can resume normal activities sooner.
  • Well-tolerated profile: In clinical studies, its efficacy and tolerability have been favorable.
Dosage

What Are the Recommended Almotriptan Dosages?

You should only take Almotriptan exactly as directed by your health care provider.

Age GroupTypical Starting DoseRepeat DoseMaximum Dose (in 24 h)Notes
Adults12.5 mg (or 6.25 mg, if risk factors present)May repeat after ≥ 2 hours if approved25 mg (two tablets of 12.5 mg)Do not use more than 2 tablets per day
Adolescents (12 to 17)6.25 mg or 12.5 mgThe same rule applies25 mg (two tablets of 12.5 mg)
Hepatic ImpairmentStart 6.25 mg≤ 12.5 mgUse caution and avoid exceeding the lower limit in severe impairment
Severe Renal ImpairmentSame as hepatic12.5 mgAdjusted in severe renal cases


Usage Guide

What Are the Usage Guidelines for Almotriptan?

Here’s how to take Almotriptan tablets correctly:

  • Timing: Swallow one tablet whole with water at the first sign of migraine head pain. Do not use it before the pain phase begins (for instance, during the aura phase).
  • Initial Dose: The recommended dose is typically 12.5 mg.
  • Repeat Dose: If your migraine symptoms are only partly relieved or if the headache returns, you may take a second dose. This second dose must be taken at least 2 hours after the first dose, and only if approved by your doctor.
  • Do Not Exceed: The maximum dose is 2 doses or 25 mg within a 24 hour period.
  • No Effect: If the first dose provides absolutely no relief, do not take a second dose for that same attack without consulting your healthcare provider first.

Important Note: Do not use Almotriptan or other acute migraine drugs for more than 10 days per month, as it can lead to medication overuse headache or rebound headache.

How It Works

How the Almotriptan Works?

Almotriptan is categorized as a selective serotonin (5-HT1) receptor agonist, or triptan.

Mechanism of Action:

  • Migraine attacks are believed to involve the widening (dilation) of blood vessels in the brain.
  • Almotriptan selectively binds to the 5-HT1B and 5-HT1D receptors located on cranial arteries, causing these blood vessels to narrow or constrict. This constriction alleviates the pain.
  • The drug also functions by blocking pain pathways and reducing neurogenic inflammation in the brain, contributing to headache relief and easing associated migraine symptoms.
Side Effects

What Are the Side Effects of Almotriptan?

Before you buy Almotriptan (Axert) online, it is essential to be aware of the possible side effects.

Common Almotriptan side effects (mild-to-moderate):

  • Drowsiness, dizziness, or sleepiness.
  • Nausea and/or vomiting.
  • Dry mouth.
  • Sensations of tingling, numbness, prickling, or burning (paresthesia).
  • General discomfort, fatigue, or weakness.
  • Chest, neck, or jaw tightness or pressure

Serious side effects (rare):

  • Cardiovascular Events: Chest pain/pressure, jaw/left arm pain, fast/irregular heartbeat, shortness of breath, sweating, or fainting. These can be signs of a heart attack or coronary artery vasospasm.
  • Neurological Events: Sudden weakness on one side of the body, slurred speech, sudden severe headache, confusion, or changes in vision (possible signs of stroke or brain bleeding).
  • Serotonin Syndrome: A very serious condition indicated by rapid heartbeat, fever, muscle twitching/stiffness, confusion, agitation, severe diarrhea/vomiting, or loss of coordination.
  • Blood Flow Issues: Pain or cramping in the hips or legs, cold sensation/color change in hands/feet (Raynaud’s syndrome), or numbness/tingling in the legs.
  • Gastrointestinal Problems: Sudden or severe abdominal/stomach pain, nausea, vomiting, fever, or bloody diarrhea (signs of ischemic bowel disease).
  • Severe Allergic Reaction: Hives, rash, swelling of the face, tongue, or throat, or trouble breathing.

Note: If any serious symptom occurs, seek emergency medical attention immediately.

Warnings

What Are the Warnings for Almotriptan?

Do not take Almotriptan tablets if you have a history of the following serious conditions:

  • Heart Disease or Cardiovascular Risk: If you have heart risk factors, take your first dose in the clinic/office so you can be watched. Your doctor may do a quick heart tracing test right after.
  • Stroke or Decreased Blood Flow: Includes stroke, mini-stroke (Transient Ischemic Attack or TIA), or decreased blood flow in the brain.
  • Uncontrolled High Blood Pressure: The medication can cause a rise in blood pressure; therefore, it should not be used if your hypertension is uncontrolled.
  • Vascular/Circulation Problems: Includes peripheral vascular disease, ischemic bowel disease (intestinal damage from blood flow issues), or Raynaud's syndrome.
  • Rare Migraine Types: Almotriptan should not be used to treat hemiplegic or basilar migraine due to a higher risk of stroke.
  • Allergies: Do not take Almotriptan (Axert) if you have a known allergy to it, other triptan migraine drugs, or any of its ingredients.
Safety Guide

What Are the Safety Guidelines for Almotriptan?

To ensure safe use of Almotriptan, discuss your full medical history with your licensed prescriber and follow these key precautions:

  • Inform your health care provider of all medical conditions, especially cardiovascular, cerebrovascular, hepatic or renal disease, and hypertension.
  • Reveal all medications and supplements to the prescriber to avoid interactions.
  • Use the shortest effective dose and avoid overuse to reduce the risks of rebound or medication-overuse headache.
  • If migraines become more frequent or no longer respond, review diagnosis or preventive options with a specialist.
  • Use Almotriptan safely in pregnancy and breastfeeding. Consult your physician about all the risks and benefits associated with this medication.
  • For first use, your provider may monitor the first dose in a supervised setting, in patients with risk factors.
Missed Dose

Since Almotriptan is taken only “as needed” during a migraine attack, missing a dose does not apply here.

Overdose

If you suspect an overdose of Almotriptan has occurred, seek immediate medical attention or contact emergency services.

Storage Guide

What Are the Storage Guidelines for Almotriptan?

  • Keep your Almotriptan tablets in their original and labeled container.
  • Place the container in a cool, dry place, like a closet or a kitchen cabinet, away from the stove or sink.
  • Store at room temperature, which is between 68°F and 77°F (20°C and 25°C). Avoid keeping it in a hot car.
  • Do not store Almotriptan in the bathroom or near a window, as extreme heat, moisture, and light can damage the tablets.
  • To prevent accidental ingestion, always keep this medication locked up and out of the sight and reach of children and pets.
  • After the expiration date, or if you no longer need this medication, dispose of it properly. Ask your pharmacist for disposal instructions.
Interactions

Mixing Almotriptan with certain medications can change how it work or increase the risk of serious side effects, such as Serotonin Syndrome. Below is a list of interactions:

Medication Class or TypeExamplesSerious Risk / Required Action
Other TriptansSumatriptan, Rizatriptan, Zolmitriptan, EletriptanDo NOT take within 24 hours of Almotriptan.
Ergot-Type MedicationsErgotamine, Dihydroergotamine, MethysergideDo NOT take within 24 hours of Almotriptan.
Antidepressants (SSRIs / SNRIs)Fluoxetine, Paroxetine, Venlafaxine, Duloxetine, St. John's wortMay increase risk of serotonin syndrome (rare). Seek urgent care for agitation, fever, rapid heartbeat, muscle stiffness, or confusion.
MAO InhibitorsPhenelzine, TranylcypromineContraindicated: Do not use Almotriptan while on an MAOI or within 14 days of stopping one.
Strong CYP3A4 InhibitorsKetoconazole, some protease inhibitors (e.g., Ritonavir)Can raise Almotriptan levels. Limit dose to 6.25 mg per dose; max 12.5 mg in 24 h when used together.
Sedating Medicines / AlcoholMuscle relaxants, narcotic pain relievers, and certain antihistaminesMay increase drowsiness/dizziness. Use caution with activities requiring alertness.

Note: Always disclose supplements, over-the-counter meds, and herbal/herbal mixes to your provider before use.

Alternatives

What Are the Alternatives for Almotriptan?

If Almotriptan is not effective or suitable, or if you are looking to manage your Almotriptan price, other acute treatments are available upon consultation with a healthcare provider.

  • Other Triptans: These prescription drugs operate via a similar mechanism to relieve migraine pain. This includes:
    • sumatriptan (Imitrex)
    • rizatriptan (Maxalt)
    • zolmitriptan (Zomig)
    • eletriptan (Relpax)
    • naratriptan (Amerge)
    • frovatriptan (Frova)
  • Gepants: Newer migraine-specific acute medications, such as Rimegepant (Nurtec) and Ubrogepant (Ubrelvy).
  • Non-Specific Painkillers: Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen, sometimes taken in combination with Almotriptan or other acute migraine drugs.
Cost & Coupons

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FAQ

Guarantee

AtPolar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently buy Almotriptan from Canada at a substantial cost, call us at 1-888-779-2193 toll-free.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

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