Arazlo

Arazlo (tazarotene) is a prescription topical retinoid used for treating acne in patients aged ≥9 years. It works by regulating skin cell growth to help reduce acne lesions and inflammation and prevent future breakouts. As an FDA-approved lotion, Arazlo should be used under the guidance of a healthcare professional to make sure safe and effective results. Some patients obtain Arazlo from licensed Canadian pharmacies to access medication, potentially at a lower cost.

Arazlo (tazarotene) 0.045% lotion is FDA‑approved for use in patients 9 years of age and older for the topical treatment of:

• Mild to moderate acne vulgaris
• Inflammatory acne lesions
• Helps reduce the formation of new acne lesions with continued use

Arazlo (tazarotene) is a topical retinoid (a vitamin A derivative) that works by normalizing skin cell turnover and preventing pore clogging. It also reduces inflammation and promotes shedding of dead skin, helping the skin become clearer and smoother. Arazlo increases sun sensitivity; use it carefully under medical guidance.

Here is a step-by-step guide on how to apply Arazlo 0.045% lotion for acne vulgaris treatment:

• Wash your face with a mild cleanser.
• Pat the skin dry (do not rub).
• Apply a small pea‑sized amount of Arazlo in a thin layer to affected areas.
• Use it once daily at night before bedtime.

• Pregnancy: Do not use Arazlo if you are pregnant or planning pregnancy (risk of fetal harm).
• Breastfeeding: It is not known whether tazarotene is excreted in human milk; use with caution and consult your healthcare provider.
• Skin sensitivity: Avoid applying to broken, sunburned, or eczematous skin.
• Sun exposure: Arazlo increases sensitivity to sunlight; always use sunscreen and limit sun exposure.
• Other products: Avoid harsh cleansers, astringents, or alcohol-based products, as they may worsen irritation.
• Children: Approved only for patients 9 years and older.

What to Avoid While Using Arazlo?

• Do not apply near the eyes, mouth, or mucous membranes.
• Avoid excessive sun exposure and tanning beds.
• Do not use more than prescribed. An extra application will not improve results and may increase irritation.
• Avoid combining with other topical retinoids unless directed by your doctor.

When Should I Stop Using Arazlo?

• Stop use and contact your doctor if you experience:
• Severe redness, swelling, or blistering of the skin
• Signs of an allergic reaction
• Persistent irritation that does not improve with moisturizer or dose adjustment.

Arazlo Missed Dose

If you forget to apply Arazlo, skip the missed dose. Do not double up or apply extra the next day. Resume your regular schedule with the next application.

Arazlo Overdose

If you suspect an overdose of Arazlo, whether due to excessive topical use or accidental swallowing, seek immediate medical attention.

Always follow your doctor’s instructions and use the lowest effective amount of Arazlo (tazarotene) 0.045% lotion.

Most of Arazlo's side effects are mild and improve with continued use or by adding a moisturizer.

Common Side Effects of Arazlo

• Skin redness
• Dryness
• Peeling or flaking
• Burning or stinging sensation
• Itching

Arazlo Less Common but Reported

• Swelling at the application site
• Rash or irritation beyond treated areas
• Increased sensitivity to sunlight (photosensitivity)

Arazlo Serious Side Effects (Rare)

• Severe local skin reactions
• Allergic reaction (difficulty breathing, hives, swelling of face/lips/tongue)

While using Arazlo (tazarotene), certain medications should be avoided or used with caution to prevent irritation or harmful effects.

Topical Medications (Increase Irritation)

• Benzoyl Peroxide
• Salicylic Acid
• Sulfur
• Resorcinol
• Azelaic Acid

Other Retinoids

• Accutane (isotretinoin, oral)
• Retin‑A (tretinoin, topical)
• Differin (adapalene, topical)

If Arazlo (tazarotene) isn’t suitable or available, the following acne treatments can be considered as an alternative under medical supervision:

Both Arazlo (tazarotene) lotion and Tretinoin are topical retinoids used to treat acne and improve skin texture. They work similarly by increasing cell turnover, unclogging pores, and reducing inflammation.

• Arazlo is a newer formulation of tazarotene designed to be gentler and less irritating, thanks to its lotion base.
• Tretinoin is the classic retinoid, widely used for decades, effective for acne and anti-aging, but often more irritating, especially at the start.

Which one is “better” depends on your skin type, tolerance, and treatment goals.

In Phase 3 clinical trials, Arazlo showed meaningful improvements in acne severity compared with placebo, with many patients noticing clearer skin after about 12 weeks of consistent use.

In vehicle-controlled Phase 3 clinical trials, Arazlo showed statistically significant reductions in inflammatory and non-inflammatory acne lesions by week 12 with consistent once-daily use. The lotion formulation was specifically developed to improve tolerability while maintaining the proven efficacy of tazarotene.

Arazlo (tazarotene) lotion can be expensive at many U.S. pharmacies, especially for patients who require ongoing acne treatment. For this reason, some patients explore licensed Canadian pharmacies as a practical way to manage long-term treatment expenses.

When you order Arazlo online from Polar Bear Meds, you may benefit from competitive Canadian pricing compared to standard U.S. pharmacy prices. In addition to pricing advantages, Polar Bear Meds offers several options that may help reduce overall medication expenses, along with a reliable ordering experience.

• https://pubmed.ncbi.nlm.nih.gov/32501793/
• https://www.arazlo.com/
• https://www.webmd.com/drugs/tazarotene-arazlo
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/211882s000lbl.pdf
• https://www.drugs.com/sfx/arazlo-side-effects.html