Atenidone

Atenidone is a prescription medication that contains atenolol, a beta-blocker commonly used to manage high blood pressure and other cardiovascular conditions. Atenolol functions by blocking specific receptors in the heart and blood vessels, helping to slow the heart rate and reduce blood pressure. This action helps manage heart-related conditions such as hypertension, angina, and irregular heart rhythms. Atenidone is a fixed-dose combination of atenolol (a beta-blocker) and chlorthalidone (a thiazide-like diuretic), available in two strengths: 50 mg/25 mg and 100 mg/25 mg.

The dosage prescribed depends on the patient's medical condition and response to treatment. It is important to take Atenidone exactly as directed by your physician, usually once daily. The medication is generally suitable for adults diagnosed with high blood pressure (hypertension), angina (chest pain), or certain types of irregular heartbeats. Atenidone helps the heart work more efficiently and decreases the risk of complications such as heart attacks or strokes. Common side effects include tiredness, dizziness, or cold hands and feet. If you have severe symptoms like swelling of the ankles, shortness of breath, or an unusually slow heartbeat, seek medical attention immediately.

Before taking Atenidone, inform your doctor if you have any respiratory problems, diabetes, or kidney issues, as these conditions require careful monitoring during treatment. You should not stop the medication suddenly without consulting your physician, as this may worsen your condition. In case of a missed dose or overdose, consult your doctor. They will guide you on what should be done in such cases. Avoid taking extra or double doses. Store Atenidone in a cool, dry place away from direct sunlight & moisture, and keep it out of reach of children. Always adhere to your healthcare provider’s instructions and discuss any concerns during treatment.

Atenidone is used to treat:

• Hypertension

The primary benefits of Atenidone include:

• It supports heart health by reducing strain on the heart.
• It removes excess fluid, which can be beneficial for conditions like edema.

What Are the Forms & Strengths of Atenidone?

It is available in the form of oral tablets, which come in the following strengths:

• 50 mg/25 mg
• 100 mg/25 mg

What Is the Recommended Dosage for Atenidone?

Atenidone dosage may vary. The typical dosage includes:

For Hypertension (Adults)

• The initial recommended dose is 50 mg orally once a day
• The maintenance dose of Atenidone for high blood pressure is 50-100 mg orally once daily.
• The maximum dose should not exceed 100mg daily.

For Hypertension (Geriatric Patients)

• Consider decreasing the initial dose of Atenidone to 25 mg once a day.

For Angina Pectoris Prophylaxis

• The initial dose of Atenidone is 50 mg orally once daily. If the optimal response is not achieved after one week, your doctor may increase it to 100 mg orally once daily.
• The maintenance dose for this medicine is 50 to 200 mg orally once daily.
• The maximum dose is 200 mg each day.

For Angina Pectoris

• The initial dose is 50 mg by mouth once daily. Based on your tolerance and response to the medicine, your doctor may increase it to 100 mg orally once a day.
• The maintenance dose of Atenidone is 50 to 200 mg orally once daily.
• The maximum dose for Angina Pectoris is 200 mg daily.

For Myocardial Infarction (Adults)

• Take 50 mg by mouth twice daily or 100 mg once daily.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they'll alter your dosage accordingly.]

Read the medication guide & follow the instructions exactly as they are mentioned.

• Atenidone may be a part of a complete treatment plan that includes other medicines, exercises, and dietary changes.
• You should take this atenolol chlorthalidone combination tablet exactly as your doctor has prescribed it. Do not take more or less than prescribed, or use it for longer than recommended, as this may cause unwanted side effects.
• The best time to take Atenidone for hypertension is in the morning, with or without food, once daily.
• You should swallow the tablet whole. Do not break, crush, or chew it. If you have difficulties swallowing it whole, ask your doctor.
• Regular monitoring of blood pressure & kidney function may be required during treatment.
• If you need to undergo surgery, including a dental procedure, you should tell your dentist or surgeon beforehand that you are using this medicine. You may need to temporarily discontinue using the medicine for a short time.
• Take the medicine as prescribed and continue even if symptoms improve. Patients with hypertension don’t usually have any symptoms.
• You should tell your doctor if your condition does not get better or if it worsens with this medicine use.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They'll adjust it as needed over time.]

Atenidone contains a combination of atenolol and chlorthalidone, a diuretic. Atenolol works by selectively blocking beta-1 adrenergic receptors in the heart, decreasing strain on the heart, and managing hypertension. On the other hand, chlorthalidone increases the excretion of sodium and chloride through urination, causing a decrease in blood pressure. Together, these components function synergistically to improve cardiovascular health by maintaining stable blood pressure levels and reducing the risk of heart-related complications.

Common Side Effects of Atenidone: Similar to other medicines, Atenidone can cause certain mild symptoms which are usually manageable and diminish over time. Common Atenidone side effects mainly include:

• Low blood pressure, especially when standing up: This is one of the most common chlorthalidone-related side effects, as it helps remove excess fluids from the body, which can lower blood pressure. However, a sudden drop in blood pressure when standing may cause dizziness or fainting.
• Cold feeling in the nose, fingers, or toes: Beta-blockers like atenolol can reduce blood flow to extremities by constricting blood vessels, causing cold extremities.
• Dizziness: This medicine lowers blood pressure, which may reduce flow of blood to the brain, causing dizziness. This effect is more pronounced when standing up quickly.
• Depression: Beta-blockers have been linked to mood changes, including depression. The exact mechanism behind this is unclear, but it may be related to decreased adrenaline activity in the brain.
• Feeling extremely weak or tired: Lowered heart rate and blood pressure can reduce oxygen delivery to muscles, leading to fatigue and weakness.
• Nausea: Chlorthalidone affects electrolyte balance, which can irritate the stomach lining and cause nausea.
• Shortness of breath: Beta-blockers can constrict airways, making breathing difficult, particularly for those with asthma or lung conditions.
• Diarrhea: Changes in fluid balance due to this medicine can affect digestion, sometimes causing diarrhea.
• Itching: Some people may experience itching due to an allergic reaction or skin sensitivity caused by the medicine.
• Rash: Skin reactions, including rashes, may occur due to a hypersensitivity reaction or irritation from the drug.
• Electrolyte changes and increased blood sugar: Chlorthalidone can cause imbalances in potassium and sodium levels, affecting muscle function and increasing blood sugar levels.
• An increase in how much you pee: Chlorthalidone, a diuretic, can increase urine production, helping to remove excess fluid and decrease blood pressure.
• Muscle pain: Electrolyte imbalances caused by chlorthalidone can cause muscle cramps or pain.

Serious Side Effects of Atenidone: Severe side effects, though less frequent, have been reported in some people using Atenidone. You should seek immediate medical attention if you experience the following reactions. These mainly include:

• Severe allergic reactions: This combination medicine can cause allergic reactions, which may be serious. You should discontinue this medicine and seek prompt medical attention if you experience symptoms of a severe allergic reaction, such as fever, breathing difficulties, swollen lymph nodes, hives, nausea, stomach cramps, joint pain, or nausea/vomiting.
• New or worsening heart failure: This medicine can worsen existing heart failure or cause a buildup of fluid in your body. For people with existing heart disease or damage, this medicine can cause potential heart failure over time. You should inform your doctor immediately if you experience trouble breathing, swelling in your feet, unusual rapid weight gain, or unusual fatigue.
• Bradycardia: The combination of atenolol and chlorthalidone can make your heart beat slower than usual. Call your doctor or healthcare provider at once if you have confusion, unusual fatigue, chest pain, or lightheadedness.
• Low blood pressure with worsening kidney function: The water loss caused by this medicine can cause low blood pressure and further lead to dehydration. Both lead to problems that are more severe than light-headedness/ poor blood flow to essential organs, such as your kidneys, may occur, especially if you are an elderly patient using Atenidone. Tell your doctor if you have weakness, sudden weight gain, confusion, decreased need to pee, increased thirst, dizziness, dry mouth, headache, rapid heartbeat, or dark-colored urine.
• Breathing problems: This medicine may cause bronchospasm in some individuals, especially those with a history of respiratory issues. This may become serious if left untreated. If you experience trouble breathing, discontinue using the drug and contact your doctor.
• Electrolyte changes and hyperglycemia: This medicine can raise your blood sugar levels and cause changes to your electrolyte levels. These changes may be serious. Your healthcare provider may recommend bloodwork to check your glucose and electrolyte levels, especially if you take certain other drugs. Its symptoms include fatigue, weakness, constipation, muscle cramps, dizziness, difficulty breathing, seizures, or restlessness.
• Severe skin reactions: Atenidone can cause severe skin reactions like SJS and TEN that can even cause death if left untreated. If you develop a rash, discontinue using it or call your doctor or healthcare provider immediately.
• Pancreatitis: This medicine can cause inflammation of the pancreas. Discontinue use and call your medical provider if you have vomiting or severe pain in the upper part of your stomach that travels to your back.
• Hepatotoxicity: This medicine can damage the liver of some users. Symptoms include nausea, vomiting, fever, itching, loss of appetite, light-colored poop, dark-colored urine, or jaundice.

[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

There are certain warnings that users should be mindful of while using Atenidone 50 mg tablets. The key points of the Atenidone warnings include:

• Allergy: Patients who have or have ever had an allergic reaction to any of the following should avoid taking Atenidone.
  • Tenoretic
  • Atenolol
  • Sulfa drug
  • Chlorthalidone

Your pharmacist or healthcare provider may tell you about all ingredients this product contains.

• Bradycardia: You should not take this medicine if your heart is beating too slowly.
• Heart block: You should not take this medicine if the electrical signals in your heart move too slowly unless you have a pacemaker.
• Severe or worsening heart failure: You should not take this product if your heart failure is severe or worsening, causing you to feel unusual fatigue, trouble breathing, or swelling in your legs.
• Cardiogenic shock: You should not take this medicine if you have a severe life-threatening condition where your heart cannot pump enough blood to the rest of your body.
• Anuria: Avoid using this medicine if you have little to no urine production.
• Very low electrolytes: If you have low potassium or sodium levels, this medicine may not be safe for you to take. Your healthcare provider may measure your electrolyte levels before you start using this medicine.
• Untreated pheochromocytoma: You should not take this medicine if you have a certain kind of adrenal gland tumor that is not being treated.

Before you decide to buy Atenidone tablets online from Canada or any other place, be mindful of the following safety information:

• Pregnancy: It is unknown whether atenolol/chlorthalidone could affect pregnancy or harm an unborn fetus. You should let your healthcare provider know if you are pregnant or plan to become pregnant. If you become pregnant while using this drug, contact your healthcare provider right away.

Breastfeeding: It is unknown if atenolol/chlorthalidone passes into breast milk, but atenolol does. Tell your physician if you are breastfeeding an infant or plan to breastfeed. They will advise you if you should take atenolol/chlorthalidone while breastfeeding.

To get the most from Atenidone for hypertension, you should stay consistent with the medicine dosage and try to take it around the same time each day to help you remember to take it. If you have missed a dose, talk to your medical provider or follow the instructions below.

• You should take the missed dose as soon as you think of it unless it is close to the time of your next scheduled dose.
• However, if the time to take your next scheduled dose is near, you may skip the missed dose and continue with your usual dosing schedule.
• Avoid taking extra or double doses of the same medicine simultaneously, as it can cause unfavorable outcomes.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

You should not take Atenidone more than the prescribed dose or more frequently, as it can lead to an overdose. An overdose of this medicine can be serious and requires prompt medical attention. Its symptoms may include severe fainting or dizziness, slow or irregular heartbeat, shortness of breath, extreme fatigue, confusion, or wheezing. If you suspect an Atenidone overdose, contact emergency services or head to the nearest medical care center at the earliest.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

After you buy Atenidone at an affordable price, it is essential to follow storage guidelines properly to make sure this medicine remains effective.

• Keep Atenidone in a controlled room temperature between 20-25°C or 68-77°F.
• You should keep the container tightly closed when not in use in a dark and cool place away from excessive heat and direct light.
• You should not keep it in the bathroom, near the sink, or in other places with high humidity, as high levels of moisture can cause harm to certain medicines.
• You should keep Atenidone tablets in a safe place that is out of sight and reach of children and pets.
• You can expose it to slightly higher temperatures for short periods, such as when transporting it.

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

Certain prescriptions, OTC drugs, herbs, or vitamin supplements may interact with Atenidone. These include

• Acarbose
• Aceclofenac
• Buprenorphine
• Celecoxib
• Dexibuprofen
• Empagliflozin
• Epinephrine
• Isocarboxazid
• Ketoprofen
• Landiolol
• Levalbuterol
• Meloxicam
• Methenamine
• Morphine
• Naproxen
• Oxymorphone
• Phenylbutazone
• Repaglinide
• Rivastigmine
• Salicylic Acid
• Sitagliptin
• Sodium Salicylate
• Tenoxicam
• Terbutaline
• Valdecoxib
• Verapamil
• Vonoprazan

What Are the Other Atenidone Interactions?

You should avoid using certain medicines at or around the same time as consuming this drug. If you are concerned about any unwanted interaction, you should let your doctor know if you use alcohol or tobacco. The presence of certain other medical problems may affect the use of this medicine. Tell your doctor if you have a history of:

• Angina
• Anuria
• Bradycardia
• Heart block
• Heart failure
• Blood vessel disease
• Gout
• Hyperuricemia
• Hypochloremia
• Hypokalemia
• Diabetes
• Hyperthyroidism
• Kidney, lung, or liver problems
• Low blood sugar
• Sympathectomy

[Note: This isn't a complete list, and there could be other drugs that interact with Atenidone. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Atenidone is commonly prescribed for hypertension, but alternatives are available for those who experience challenges with it. Suitable options should always be explored under medical supervision, whether due to intolerance, lack of effectiveness, or other reasons. Some substitutes to Atenidone include;

• Lisinopril
• Amlodipine
• Hydrochlorothiazide
• Atenolol
• Norvasc
• Carvedilol

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

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