Aviane

Aviane is a combination oral contraceptive pill containing levonorgestrel (a progestin) & ethinyl estradiol (an estrogen). Primarily, it prevents pregnancy by inhibiting ovulation, making cervical mucus thicker to stop sperm, and thinning the uterine lining to prevent implantation. Beyond contraception, Aviane helps regulate menstrual cycles, reduce heavy bleeding, and alleviate painful cramps. It is also prescribed for hormonal imbalances, such as polycystic ovary syndrome (PCOS), and can improve hormonal acne and premenstrual symptoms like mood swings and bloating. Additionally, long-term use may lower the risk of ovarian cysts, ovarian cancer, and endometrial cancer.

Aviane is available in 21-day and 28-day tablet packs, with each active pill containing 0.10 mg of levonorgestrel & 0.02 mg of ethinyl estradiol. For optimal effectiveness, it must be taken at the same time daily, with no more than 24 hours between doses. Common side effects of Aviane include nausea, breast tenderness, breakthrough bleeding, and mild weight gain, though these often subside as the body adjusts. However, serious risks—such as blood clots, stroke, and heart attack—are associated with hormonal contraceptives, particularly in smokers, women over 35, or those with serious health conditions like hypertension.

Before using Aviane, consult a healthcare provider to assess suitability, especially if you have liver disease, cardiovascular risks, or undiagnosed vaginal bleeding. It interacts with medications like antibiotics, anticonvulsants, and St. John’s Wort, which may reduce its efficacy. Non-hormonal alternatives or progestin-only options may be recommended for certain individuals. Always follow medical guidance to ensure safe and effective use.

This medication is used to:

• Prevent Pregnancy: Inhibits ovulation and thins the uterine lining to prevent implantation.
• Regulate Menstrual Cycles: Helps maintain consistent and predictable periods.
• Manage Menstrual Disorders: Reduces heavy bleeding and alleviates painful cramps.
• Treats Hormonal Imbalances: Often prescribed for conditions like PCOS to stabilize hormone levels.

Benefits

When you buy Aviane online, you can get the following benefits:

• Improves Hormonal Acne: Some formulations help clear acne by balancing hormones.
• Relieves PMS Symptoms: Reduces mood swings, bloating, and other premenstrual discomforts.
• Lowers Risk of Certain Conditions: May decrease the likelihood of ovarian cysts, ovarian cancer, and endometrial cancer.

What Are the Forms & Strengths of Aviane?

Aviane is available in tablet form with 21 and 28-day packs. This medication has only one strength for each tablet:

• 0.10 mg of levonorgestrel & 0.02 mg of ethinyl estradiol

What Is the Typical Dosage for Aviane?

To ensure maximum effectiveness, Aviane (levonorgestrel & ethinyl estradiol tablets) must be taken exactly as directed, with no more than 24 hours between doses.

Usual Adult Dose for Contraception

• Active (orange) tablets: Take 1 tablet daily for 21 consecutive days.
• Inert (light-green) tablets: Take 1 tablet daily for the next 7 days.
• Dosing Tip: Take the pill at the same time every day for best results.

[Note: Remember, these recommendations might vary from person to person. Discuss it with your doctor or pharmacist, and they will customize your dosage accordingly.]

When you buy Aviane online from Canada, consider the following administration guidelines:

• Take the Aviane pill exactly as prescribed by your doctor, following all directions on the prescription label.
• Read all medicine guides or instruction sheets provided.
• Start your first pill:
  • On the first day of your period or
  • On the first Sunday after your period begins (follow your doctor's instructions).
• Use backup birth control (e.g., condoms, spermicide) when first starting Aviane, as directed.
• Take one pill every day, no more than 24 hours apart.
• Start a new Aviane pack the day after finishing the previous one to avoid gaps.
• Missing a pill increases the risk of pregnancy—refill your prescription before running out.
• If your pack includes 7 "reminder" pills (inactive pills), take them to stay on schedule—your period will likely occur during this time.
• For chewable tablets:
  • Chew and swallow with water or
  • Swallow whole if preferred.
• Take on an empty stomach for best results.
• Use backup birth control if you experience severe vomiting or diarrhea.

[Note: Your doctor will decide the right Aviane amount for you based on your medical condition, following guidelines & studies on the medication. They'll adjust it as needed over time.]

Aviane prevents pregnancy through a combination of hormonal mechanisms. It contains levonorgestrel and ethinyl estradiol, which inhibit ovulation, meaning not even a single egg is released for fertilization. Moreover, it thickens the cervical mucus to block sperm from reaching the uterus and alters the uterine lining, making it less ideal for a fertilized egg to implant. When taken as directed, these actions work together to provide effective contraception. However, Aviane does not protect against sexually transmitted infections (STIS). For optimal effectiveness, consistency in daily intake is crucial.

Common Aviane Side Effects: Like all medications, Aviane can cause side effects. Here are some of them listed:

• Nausea: Nausea is a very common side effect when starting Aviane, as the body adjusts to hormonal changes. Taking an Aviane pill with food or at bedtime can help reduce discomfort. If nausea continues beyond the first few months, consult a healthcare provider.
• Breast Tenderness: Hormonal fluctuations from Aviane can cause breast swelling and tenderness, similar to premenstrual symptoms.
• Breakthrough Bleeding: Irregular spotting or light bleeding between periods is common in the first few months of using Aviane. This happens as the uterus adapts to the hormones. If breakthrough bleeding continues beyond three months, medical advice is recommended.
• Acne: While some women experience improved skin, others may develop acne due to hormonal shifts. If acne worsens, a dermatologist can recommend treatments that work alongside birth control.
• Darkening of Facial Skin (Melasma): Aviane may cause dark patches on the face, especially in women prone to hyperpigmentation. Sun exposure worsens this effect, so daily sunscreen use is essential. Melasma often fades after stopping the pill.
• Weight Gain: Some users report mild weight gain, typically due to retention of the water rather than fat accumulation. Staying hydrated, reducing salt intake, and exercising regularly can help manage this effect.
• Problems with Contact Lenses: Hormonal changes can lead to dry eyes, making contact lenses uncomfortable. Lubricating eye drops or switching to glasses temporarily may provide relief.

Serious Aviane Side Effects: Aviane is a birth control pill that’s generally safe for most people, but like all hormonal contraceptives, it can cause side effects, some of which may be serious.

• Blood Clots: Aviane increases the risk of blood clots, particularly in the legs or lungs (pulmonary embolism). Symptoms include sudden leg pain, swelling, or redness. Seek emergency care if these occur.
• Heart Stroke: Women taking Aviane have a slightly higher risk of stroke, especially if they smoke, have high blood pressure, or have a history of blood clots. Warning signs include sudden weakness, confusion, or trouble speaking.
• Heart Attack: Though rare, Aviane may contribute to heart attack risk, particularly in women over 35 who smoke. Shortness of breath, serious chest pain, or pain radiating to the arm or jaw requires immediate medical attention.
• Severe Headaches: Sudden, intense headaches—especially migraines with aura—could indicate an increased stroke risk. Discontinue Aviane and consult a doctor if these occur.
• Chest Pain: Unexplained chest pain may signal a blood clot in the lungs or heart complications. Immediate medical attention is necessary to rule out life-threatening conditions.
• Vision Changes: Blurred vision, partial blindness, or seeing flashing lights may indicate a blood clot in the eye or high blood pressure. Stop Aviane and seek emergency care if these symptoms appear.
• Unusual Swelling or Leg Pain: Pain, warmth, or swelling in the legs, especially in one leg, could signal deep vein thrombosis (DVT). If left untreated, a clot may travel to the lungs, causing a pulmonary embolism.

[Note: Remember, this list might not cover all possible Aviane side effects. Always consult with your doctor or healthcare expert for medical advice about side effects.]

Before you buy Aviane online from Canada, consider the following warnings associated with this medication:

• Pregnancy and Postpartum Warning: Do not use Aviane if you are pregnant or have recently given birth. Aviane is a hormonal birth control pill intended to prevent pregnancy, not to terminate an existing one. Taking hormonal contraceptives during pregnancy may pose risks to fetal development. Additionally, suppose you have recently had a baby. In that case, your body needs time to recover, and introducing hormonal contraception too soon can increase the chance of blood clots, especially if you have other major risk factors such as a history of clotting disorders or a cesarean delivery.
• Cardiovascular and Circulatory Risks: You should not use Aviane if you have uncontrolled high blood pressure, heart disease, coronary artery disease, or circulation problems (especially if you have diabetes). Hormonal birth control may increase blood pressure and may worsen cardiovascular conditions. The estrogen in Aviane can contribute to blood clot formation, which may lead to DVT (deep vein thrombosis), pulmonary embolism (PE), heart attack, or stroke. If you have a history of blood clots, stroke, or heart attack, Aviane is not safe for you.
• Liver Disease and Cancer Concerns: Aviane is contraindicated if you have liver disease, liver cancer, or a history of jaundice caused by pregnancy or previous birth control use. The liver processes hormonal contraceptives, and impaired liver function could lead to a dangerous buildup of hormones in the body. Additionally, if you have (or have had) hormone-sensitive cancers such as breast, uterine, cervical, or vaginal cancer, Aviane may stimulate cancer growth due to its estrogen and progestin components.
• Migraine and Medication Interactions: Avoid Aviane if you suffer from severe migraine headaches, particularly those with aura, as hormonal birth control can increase the risk of stroke in migraine sufferers. Additionally, certain hepatitis C medications (such as those containing ombitasvir/paritaprevir/ritonavir) can interact with Aviane, increasing liver toxicity and the risk of abnormal liver function. Always inform your doctor of all medications you are taking before starting Aviane.
• Surgical and Smoking Risks: If you are scheduled for major surgery (especially procedures requiring prolonged immobilization), you should stop taking Aviane at least 4 weeks beforehand due to the increased risk of blood clots. Additionally, smoking while on hormonal birth control significantly elevates the risk of serious cardiovascular events, including blood clots, stroke, and heart attack. If you smoke and are over 35 years old, you should not use Aviane, as the combination of smoking and hormonal contraception drastically increases these dangers.
• Undiagnosed Vaginal Bleeding: If you experience unusual or undiagnosed vaginal bleeding, consult your doctor before using Aviane. Unexplained bleeding could indicate an underlying condition (such as infection, hormonal imbalance, or cancer) that may be worsened by hormonal contraception. Proper diagnosis is essential to ensure safe use of birth control pills.
• General Risks of Hormonal Birth Control: All hormonal contraceptives, including Aviane, carry a risk of blood clots, stroke, and heart attack, even in healthy individuals. The risk is higher in the first year of use and when restarting after a break. Watch for sudden or severe symptoms like chest pain, leg swelling, headaches, vision changes, or trouble breathing, and get medical help right away if they happen.
• Eye Disorders: Women using Aviane may develop fluid retention in the cornea, which can lead to vision changes or difficulty wearing rigid (hard) contact lenses. Soft contact lenses typically do not cause these issues. If you experience vision problems or discomfort with contacts, you may need to discontinue use.
• Fibroids: Aviane may aggravate existing fibroids, leading to rapid growth, pain, or tenderness. If you notice any of these signs, consult your doctor quickly.

Pancreatitis: Some women taking levonorgestrel-ethinyl estradiol may experience elevated blood triglyceride levels, which can lead to pancreatitis (inflammation of the pancreas) if left untreated. Pancreatitis can be severe and requires immediate medical attention. Watch for symptoms such as upper left abdominal pain, back pain, nausea, fever, chills, rapid heartbeat, or abdominal swelling, and contact your doctor if they occur.

Here are some important precautions to consider when using Aviane:

• Medical Conditions to Discuss with Your Doctor: Before starting Aviane, inform your healthcare provider if you have a history of heart disease, high blood pressure, blood clots, high cholesterol, obesity, depression, seizures, migraines, diabetes, gallbladder disease, liver or kidney problems, irregular menstrual cycles, or breast abnormalities (such as fibrocystic disease or abnormal mammograms). Your doctor will assess whether Aviane is safe for you or recommend an alternative contraception.
• Breastfeeding Considerations: Aviane can reduce breast milk production, making it unsuitable for nursing mothers. If you are breastfeeding, consult your doctor for alternative birth control methods that do not interfere with lactation. Avoid using Aviane until you have fully weaned your baby to ensure proper milk supply and infant health.
• Children: This medication is not recommended for girls who have not started menstruating or for children under 14 years of age.

Return to Fertility: After stopping birth control, wait until you have at least one natural menstrual cycle before attempting pregnancy to help determine conception timing. Use an alternative contraceptive method during this period. If menstruation does not resume within six months after stopping the pill, seek medical advice.

Missing Aviane pills at any time increases the risk of pregnancy. If you miss one pill, take it as soon as you remember & continue with the next pill at the usual time, which may mean taking two pills in one day. If you miss two pills in a row during the first two weeks of your cycle, take two pills on the day you remember and two the next day, then resume one pill daily until the pack is finished—use a backup birth control method for 7 days after the missed pills. For those who start their pills on Sunday and miss two pills in a row during the third week or three or more pills anytime in the cycle, continue taking one pill daily until Sunday, then discard the remaining pack and start a new one that day, using backup protection for seven days. If you start your pills on a different day and miss two pills in the third week or three or more anytime, discard the rest of the pack & start a new one immediately, using an alternative birth control method for the next seven days—you may miss your period this month, but if you miss two in a row, contact your doctor or clinic.

[Note: If you have missed a dose of your medicine & are unsure about when to take the next one, consult your doctor immediately.]

An overdose of Aviane, a combination oral contraceptive, can lead to various symptoms like vomiting and drowsiness. If an Aviane overdose is suspected, it is important to seek medical attention quickly to manage symptoms and prevent potential complications.

[Note: If you consumed more than the recommended Aviane dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

Aviane pills should be stored properly to maintain their effectiveness. Here are the general guidelines:

• Store Aviane at room temperature, typically between 20°C-25°C (68°F-77°F). Avoid exposing these pills to extreme heat or cold.
• Keep these pills in a dry place, away from moisture.
• Protect Aviane pills from direct sunlight and store them in their original packaging.
• Store Aviane pills out of reach of children to prevent accidental ingestion.

[Note: Discuss with your healthcare giver about the proper disposal of any unused Aviane pills and any questions you may have regarding their storage.]

If you plan to buy Aviane online to prevent ovulation, consider the following drug interactions:

• Bosentan
• Clarithromycin
• Anastrozole
• Brigatinib
• Dabrafenib
• Eslicarbazepine
• Belzutifan
• Carfilzomib
• Acitretin
• Exemestane
• Boceprevir
• Dantrolene
• Amprenavir
• Baricitinib
• Encorafenib
• Etretinate
• Elafibranor
• Bexarotene
• Carbamazepine
• Abrocitinib

What Are the Other Aviane Interactions?

Apart from medication interactions, Aviane can interact with the following:

• Disease Interactions of Aviane: There are 24 known disease interactions of Aviane. Some of them are listed below:
  • Abnormal Genital Bleeding: Aviane, a combined oral contraceptive containing estrogen and progestin, is contraindicated in cases of undiagnosed abnormal genital bleeding. The presence of unexplained bleeding may indicate underlying conditions such as endometrial hyperplasia or malignancy, which could be exacerbated by hormonal contraceptives. Before initiating Aviane, a thorough diagnostic evaluation—including endometrial biopsy if necessary—should be performed to rule out malignant or premalignant conditions. If abnormal bleeding persists or recurs during treatment, further assessment is required to determine the cause and whether discontinuation of the contraceptive is necessary.
  • Estrogen-Related Abnormal Vaginal Bleeding: Aviane contains ethinyl estradiol, an estrogen that can contribute to abnormal vaginal bleeding, particularly when used without adequate progestin opposition. Unopposed estrogen therapy has been linked to an increased risk of endometrial carcinoma, which the progestin component in Aviane may partially mitigate. However, the risk is not entirely eliminated. Patients with undiagnosed vaginal bleeding should undergo diagnostic testing (e.g., ultrasound, biopsy) before starting Aviane. If persistent or recurrent bleeding occurs during treatment, reevaluation is essential to exclude malignancy or other serious conditions.
  • Estrogen-Dependent Cancers: Estrogens in Aviane may stimulate the growth of estrogen-dependent tumors, including breast and endometrial cancers. Therefore, Aviane is contraindicated in patients with known or suspected estrogen-sensitive malignancies. While high-dose estrogens are sometimes used in palliative treatment for metastatic breast cancer, this does not apply to low-dose contraceptive formulations like Aviane.
  • Hypercalcemia in Breast Cancer: Patients with breast cancer and bone metastases who take estrogen-containing contraceptives like Aviane may experience severe hypercalcemia due to increased bone resorption. If hypercalcemia develops, immediate discontinuation of Aviane is necessary, along with interventions to lower serum calcium levels (e.g., hydration, bisphosphonates). Monitoring calcium levels in high-risk patients is advisable if estrogen therapy is required.
  • Hypertension: Aviane may increase blood pressure, elevating the risk of cardiovascular problems such as stroke and myocardial infarction, particularly in women with preexisting hypertension. The risk is higher in older patients (over 35), smokers, and those with uncontrolled hypertension. Blood pressure should be monitored regularly in users of Aviane, and if significant hypertension develops, discontinuation may be necessary. For hypertensive patients requiring contraception, non-hormonal or progestin-only alternatives may be safer options.
  • Hepatic Neoplasms: Aviane, which contains both estrogen and progestin, is contraindicated in patients with liver tumors due to an increased risk of benign hepatic adenomas and hepatocellular carcinoma with long-term use. Studies suggest that hepatic adenomas may develop after at least four years of oral contraceptive use, while hepatocellular carcinoma risk rises after approximately eight years. Although these tumors are rare, Aviane and other estrogen-progestin contraceptives should be avoided in individuals with existing liver tumors, including hepatic hemangiomas and nodular hyperplasia. Patients with a history of liver tumors should explore non-hormonal contraceptive alternatives.
  • Breast Cancer: Progestogens, including the progestin component in Aviane, may be contraindicated in patients with existing or suspected breast cancer. Some evidence suggests that progestin-only contraceptives, particularly injectable medroxyprogesterone acetate, may increase breast cancer risk, especially within the first five years of use. While Aviane contains a different progestin (levonorgestrel), manufacturers generally advise against its use in women with a history of breast cancer due to potential hormonal stimulation of tumor growth. Patients with a personal or strong family history of breast cancer should discuss alternative contraceptive options with their healthcare provider.
  • Liver Disease: Aviane should be used with caution in patients with liver dysfunction, as progestogens and estrogens are metabolized in the liver. Severe hepatic impairment can lead to decreased drug clearance, increasing the risk of adverse effects. Jaundice or worsening liver function during treatment may necessitate discontinuation. Women with active liver disease, such as hepatitis or cirrhosis, should avoid Aviane and consider non-hormonal contraception.
  • Angioedema: Estrogens in Aviane may trigger or worsen angioedema, particularly in women with hereditary angioedema. Exogenous estrogens can increase vascular permeability, leading to swelling episodes. Patients with a history of angioedema should be monitored closely if using Aviane, and alternative contraceptives may be preferable if recurrent symptoms occur.
  • Gallbladder Disease: Estrogen-containing contraceptives like Aviane may increase the risk of gallbladder disease by promoting cholesterol saturation in bile. Postmenopausal estrogen therapy has been linked to a two-to-four-fold higher risk, though the effect may be less pronounced with low-dose contraceptives. Women with a history of gallstones or gallbladder disease should use Aviane cautiously and be monitored for symptoms such as biliary pain or cholecystitis.
  • Hypercalcemia: Aviane’s estrogen component can enhance calcium absorption and retention, potentially leading to hypercalcemia in susceptible individuals. Patients with hyperparathyroidism, renal dysfunction, or metabolic bone disorders should be monitored for elevated calcium levels while using Aviane. If hypercalcemia develops, discontinuation and appropriate treatment (e.g., hydration, bisphosphonates) may be necessary.
  • Hyperlipidemia: Although estrogens in Aviane generally improve lipid profiles by raising HDL and lowering LDL cholesterol, they can also increase triglyceride levels. Severe hypertriglyceridemia may predispose patients to pancreatitis, particularly those with preexisting lipid disorders. Women with hyperlipidemia should have regular lipid monitoring while using Aviane, and alternative contraception may be needed if significant triglyceride elevations occur.
• Alcohol: Aviane may interact unpredictably with alcohol, potentially increasing both central nervous system (CNS) effects and blood ethanol levels. While data on this interaction is limited and somewhat contradictory, some evidence suggests that oral contraceptives like Aviane could inhibit enzymes involved in alcohol metabolism, leading to prolonged or heightened intoxication. Women taking Aviane should be cautious when consuming alcohol, as they may experience stronger effects (e.g., drowsiness, impaired coordination, or prolonged intoxication) compared to those not on hormonal contraception.
• Herbs & Supplements: Aviane, a contraceptive containing ethinyl estradiol and levonorgestrel, can interact with certain herbal supplements, potentially altering its effectiveness or increasing side effects. For example, St. John's Wort is known to reduce the efficacy of hormonal contraceptive pills by speeding up their metabolism, raising the risk of unintended pregnancy.

[Note: This is not a complete list, and there could be other drugs that interact with Aviane. Make sure to tell your doctor or pharmacist about any prescription, over-the-counter medicines (OTC), and herbal products you’re taking.]

If you're considering alternatives to Aviane, several options are available depending on your preferences. Some common alternatives include:

• Mirena
• Nexplanon
• Sprintec
• Vienva

[Note: Your doctor or pharmacist will choose what is best for you. Don’t use any of these alternative medicines without consulting your healthcare provider. Taking them by yourself might cause serious side effects.]

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