Trajenta

Trajenta is a prescription oral medication that contains linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. It is used to help control blood sugar in adults with type 2 diabetes mellitus, when taken along with diet and exercise. Trajenta works by regulating incretin hormones in the body, which helps improve insulin release and reduce glucose production by the liver.

Trajenta is not insulin and should not be used to treat diabetic ketoacidosis or type 1 diabetes. It is available only by prescription from a licensed healthcare provider.

Trajenta is the international brand name for linagliptin and is marketed outside the United States. In the United States, linagliptin is approved by the FDA under the brand name Tradjenta. While both contain the same active ingredient and work in the same way, Trajenta itself is not an FDA-approved U.S. brand name.

Trajenta (linagliptin) is contraindicated in patients who have:

• A history of serious hypersensitivity reactions to linagliptin or any component of the formulation

Before taking Trajenta (linagliptin), keep the following precautions in mind:

• Trajenta is not indicated for use in diabetic ketoacidosis or Type 1 diabetes.
• Monitor for low blood sugar (hypoglycemia), especially when Trajenta is used together with insulin or sulfonylureas.
• DPP‑4 inhibitors, including linagliptin, have been associated with heart failure; monitor patients at risk.
• Discontinue Trajenta and seek medical attention if signs of a serious allergic reaction occur, like swelling of the lips, face, tongue, or throat.
• Rare cases of bullous pemphigoid have been reported; discontinue if suspected.
• Do not stop or change the dose of Trajenta without consulting your healthcare provider.

Trajenta (linagliptin) works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). By blocking DPP-4, Trajenta:

• Increases levels of incretin hormones (GLP-1 and GIP)
• Enhances glucose-dependent insulin release from the pancreas
• Reduces glucagon secretion, which lowers glucose production by the liver

Together, these effects help improve blood sugar control in adults with Type 2 diabetes.

Trajenta should be taken exactly as prescribed by a healthcare provider to help maintain consistent blood sugar control in adults with Type 2 diabetes.

Trajenta Dosage for Adults

• Recommended dose: 5 mg once daily with or without food.

Combination Therapy

• Trajenta may be used alone or with other diabetes medicines such as metformin, sulfonylureas, or insulin.
• When used with insulin or sulfonylureas, a lower dose of those medicines may be needed to reduce the risk of low blood sugar.

Trajenta Missed Dose

• If you miss a dose, take it as soon as you remember.
• If it is close to your next dose, skip the missed one.
• Do not take two Trajenta doses at the same time.

This list is not complete. Contact your prescriber if you experience serious symptoms or unusual changes.

Common Side Effects of Trajenta (linagliptin)

• Nasopharyngitis (common cold symptoms)
• Cough
• Joint pain (arthralgia)
• Headache
• Constipation
• Vomiting
• Diarrhea

Trajenta Serious Side Effects (Require Medical Attention)

• Pancreatitis: Sudden severe stomach pain, nausea, vomiting, loss of appetite.
• Hypoglycemia: When used with insulin or sulfonylureas.
• Severe allergic reactions: Swelling of the face, lips, tongue, or throat; difficulty breathing.
• Heart failure: Swelling of ankles/feet, shortness of breath, sudden weight gain.
• Bullous pemphigoid (rare skin condition)

Trajenta (linagliptin) can be taken at any time of day, because its effectiveness is not dependent on meals. What matters most is taking it once a day at the same time, so it becomes part of your routine. You may take it in the morning or evening, with or without food.

Here is a list of drugs that may interact with Trajenta (linagliptin):

If Trajenta is unavailable or not suitable, consider the following alternative medications under medical supervision:

• Januvia (sitagliptin)
• Onglyza (saxagliptin)
• Nesina (alogliptin)
• Galvus (vildagliptin)

Many patients may choose to order Trajenta from Canada because it is often more affordable than U.S. retail prices. At Polar Bear Meds, we source our medications from a network of licensed Canadian and international pharmacies and follow regulated dispensing standards to ensure medication quality and safety. When you buy Trajenta online from our pharmacy, you can save a significant amount, often at prices lower than typical U.S. retail rates.

Buying Trajenta from Canada requires a valid prescription from a licensed medical provider. You can also enjoy several savings programs, including:

• Use a Trajenta coupon to get 10% off your first order.
• Competitive pricing
• Referral programs

• https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/201280lbl.pdf
• https://www.mayoclinic.org/drugs-supplements/linagliptin-oral-route/description/drg-20074875
• https://my.clevelandclinic.org/health/drugs/19943-linagliptin-tablets
• https://www.webmd.com/drugs/linagliptin-tradjenta