Brimonidine Tartrate

Brimonidine P Eye Drops 

Brimonidine P Eye Drops 0.15% is an alpha-2 (α2) adrenergic receptor agonist that has gained FDA approval to reduce intraocular pressure (fluid pressure in the eye) in patients suffering from open-angle glaucoma or ocular hypertension (a type of eye disease). The medication works by reducing the amount of fluid in the eyes. It is available as an ophthalmic solution with two different strengths of 1 and 1.5 mg/ml. Doctors usually advise using the eye drops thrice daily as instructed. It is important to keep a gap of 8 hours between each dose. This medication is suitable for adults but is not recommended for use in children less than 2 years of age. Lastly, always trust reliable sources to buy affordable Brimonidine P for intraocular pressure management.

Product Overview 

Brimonidine P Eye Drops (0.15%) contain Brimonidine tartrate as their primary active ingredient. This medication effectively lowers high intraocular pressure in people with ocular conditions such as open-angle glaucoma or ocular hypertension. These eye drops are available at 1 and 1.5 mg/ml strength and are administered topically. It is recommended to take one drop into the affected eye three times daily, approximately eight hours apart. 

This ophthalmic solution is suitable for adults diagnosed with glaucoma or ocular hypertension and functions by decreasing fluid production in the eye and improving fluid drainage. These eye drops are usually well-tolerated, but they may cause some side effects, including eye irritation, dry mouth, and occasional dizziness. Patients experiencing these or any other unusual symptoms should seek advice from their healthcare provider. 

When considering treatment with Brimonidine P for ocular hypertension, patients must be aware of certain precautions to avoid the risk of potential complications. This includes avoiding contact with soft lenses while applying the eye drops and waiting for 15 minutes before reinserting them. It is important to stick to the recommended dosage, as administering more than the prescribed dose can lead to overdose, requiring immediate medical attention. If you plan to buy Brimonidine eye drops online, consult your doctor for proper uses, dosage, and associated risks and benefits. 

What Are the Uses of Brimonidine P Eye Drops?

These eye drops are used for:

• Treating open-angle glaucoma or high fluid pressure in the eye.
• Reducing the chances of vision loss, nerve damage, or blindness.

What Forms & Strengths Do Brimonidine Eye Drops Come In?

The solution comes in two strengths:

• Brimonidine tartrate 1 mg/mL
• Brimonidine tartrate 1.5 mg/mL

What Is the Recommended Dosage for Brimonidine P Eye Drops?

The recommended dosage for Brimonidine eye drops varies depending on the individual’s age and the severity of the medical condition. Doctors usually prescribe a starting dose and adjust it accordingly as per each individual’s response to the treatment. If your dosage is different, do not change it without discussing it with your doctor. The following section includes only the average dosage. If you plan to buy Brimonidine from Canada, talk to your doctor for appropriate doses.

For Glaucoma

• Adults & Children Over 2 Years: For this age group, only one drop of Brimonidine in the affected eye, 3 times a day. The duration should be 8 hours apart. 
• Children Younger Than 2 Years: It is not recommended.

For Redness of the Eye

• Adults & Children Above 5 Years: One drop every 6 to 8 hours in the infected eye.
• Children Below 5 Years: Consult your physician to determine the appropriate use and dosage.

[Note: Remember these recommendations may vary from person to person. Discuss it with your healthcare professional, and they’ll customize your dosage accordingly.]

How to Apply Brimonidine Eye Drops?

Proper administration is important to increase the effectiveness of the medication. If you plan to buy Brimonidine eye drops online, here are some important steps on how to apply these eye drops effectively:

• Thoroughly wash your hands before and after using the eye drops to avoid any inflammation or infection.
• Make sure to shake the eye drops well just before each use.
• To apply the drops, tilt your head back and use your finger to gently pull down the lower eyelid, creating a small space. Carefully drop the medicine into this space. Release the eyelid and close your eyes gently, without blinking. Keep your eyes closed for a few minutes. This helps the medicine absorb properly.
• If the drops did not properly get into the eyes, repeat the process with a second drop.
• To maintain the sterility of the medicine, avoid touching the applicator tip to any surface, including the eye. Always keep the container tightly closed when not in use.
• If bacteria contaminate the bottle, it could lead to a serious eye infection, potentially causing blindness.
• The eye drops should appear as a clear liquid with a greenish-yellow color. If you notice a change in color or the liquid turns cloudy, stop using it and get a new bottle from the pharmacy.

[Note: Your healthcare provider will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Brimonidine P Eye Drop Work?

Brimonidine Tartrate works by targeting specific receptors like alpha-2 adrenergic in the eyes. When this eye drop is used in the affected eye, it connects to these receptors, thus reducing the fluid amount (aqueous humor) produced in the eye. Additionally, the medication affects the blood vessels in the eye, causing them to narrow down. This process helps in managing the pressure inside the eye. 

With long-term use, Brimonidine also increases the drainage of fluid from the eye through a pathway called the uveoscleral outflow. This dual action of reducing fluid production and increasing fluid outflow effectively lowers intraocular pressure (IOP) in the eye. As a result, these eye drops help prevent damage to the optic nerve, which is important for maintaining clear vision and preventing the progression of glaucoma. 

Important Safety Information for Using Brimonidine P Eye Drop

What Are the Side Effects of Brimonidine P Eye Drop?

Common Side Effects of Brimonidine: This medication can cause certain side effects in many patients. These effects are generally temporary and happen at the start of the treatment. Once your body adjusts to the medication’s effects, the effects lessen over time. However, if they become severe and persist more than the mentioned period, contact your doctor right away. Some of these common side effects may include:

• Itching or Irritated Eyes: It is a common side effect of Brimonidine P Eye Drops that occurs because the medication can cause mild inflammation or an allergic reaction in some individuals. The irritation and itching usually happen at the start of the treatment and subside within a few days or weeks. To manage this, try using lubricating eye drops to soothe the irritation. 
• Blurred Vision: You can experience blurred vision immediately after applying the eye drops. This is because the drug affects fluid drainage in the eye, thus temporarily impacting vision. The effect usually diminishes as your eyes adjust to the medication. In such situations, avoid driving or using machines immediately after using the medication.
• Excessive Tearing: Watery eyes can caused due to a reaction to the eye drops. This side effect may be caused due to the eye trying to wash away the medication. There is nothing serious about this side effect; just gently dab away the excess tears using a clean tissue. If the tearing becomes severe or persistent, talk to your doctor. They may suggest a different type of eye drop or adjust the dosage.  
• Headache: This side effect occurs due to the medication’s effect on blood vessels and circulation. It is not a serious effect and usually lessens over time once your body adjusts to the drug. In the meantime, you can avoid headaches by staying well-hydrated, resting in a dark, quiet room, and using over-the-counter pain relief. 
• Tiredness: Feeling tired or drowsy is another possible side effect of Brimonidine P eye drops. This side effect happens because the medication may affect the central nervous system. It is a temporary effect that disappears over time. To manage this, take proper rest and avoid activities that require a sharp mind, such as driving or using machines, until you know how the drops affect you. 
• Halos Around Lights: This ophthalmic solution can affect the fluid pressure in the eye, altering the user’s vision temporarily. It is usually experienced immediately after applying the eye drops but will diminish as your eyes adjust to the medication. To prevent any potential injury, avoid driving or using heavy machines immediately after using the medication.  
• Redness on the Inner Lining of the Eyelid: This medication can cause irritation in the eyes, causing redness on the eyelid. This results from an allergic reaction or sensitivity to the medication. Try using a cool compress on the eyelid to manage this side effect. This helps reduce redness and irritation. However, if the redness persists or worsens, consult your doctor right away. 
• Eyelid Swelling: This is one of the common side effects of Brimonidine eye drops. It can occur as a reaction to the eye drops, usually due to an allergic reaction or irritation. Applying a cold compress to the swollen part can help minimize swelling. 

Serious Side Effects of Brimonidine: Besides the basic reactions, this medication can result in many severe side effects, which, if left untreated, lead to fatal situations. When considering Brimonidine P eye drops for glaucoma treatment, beware of any unusual signs or symptoms and report them to your doctor right away. Some of these serious side effects may include:

• Loss of Eyesight: It is a rare but serious side effect of Brimonidine P eye drops. This side effect happens due to an adverse reaction to the medication, affecting the optic nerve or causing severe inflammation in the eye. To reduce this risk, follow your medical provider’s instructions carefully and report any vision changes immediately. 
• Bloody Eye: This side effect results from severe irritation or an allergic reaction to the eye drops. It might be due to the drug causing damage to the blood vessels present in the eye. Do not overlook this condition, as it may lead to fatal situations. If you notice any unusual signs, avoid rubbing your eyes and seek medical assistance right away. They will examine the condition and suggest alternate treatment options.
• Increased Heartbeats: Tachycardia can be caused due to the medication’s systemic absorption and its effects on the cardiovascular system. This is a rare but serious side effect, which, if left overlooked, can lead to life-threatening situations. The effect can worsen by consuming caffeine and other stimulants. If you are experiencing persistent or severe tachycardia, consult a medical professional. They will examine your condition and may adjust the medication.
• Persistent Headache: This can be a serious side effect of Brimonidine P eye drops, generally due to fluctuations in blood flow or pressure within the eye. If the headaches are persistent even after staying well-hydrated and using over-the-counter pain relievers, talk to your doctor. They may adjust your treatment plan.
• Severe Eye Pain: Severe eye pain can occur as a serious side effect of Brimonidine eye drops, which usually happens due to an adverse reaction or increased intraocular pressure. Neglecting the pain may worsen the condition. In such a situation, avoid touching or rubbing the eyes and use a cold compress to reduce the discomfort. If the pain persists, seek immediate medical assistance, as this could be an early indication of a serious underlying issue that needs prompt treatment. 

[Note: Remember, the above list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Brimonidine P Eye Drops?

While safe to use, Brimonidine contains several warnings. Being aware of these warnings reduces the risk of potential side effects. Before using Brimonidine P eye drops for glaucoma treatment, you must know the following warnings:

• Vascular Insufficiency: Sold under the brand name Alphagan P Brimonidine, it may increase the risk of conditions that are linked to poor blood flow. It should be used cautiously in patients with brain problems, Raynaud’s phenomenon, and orthostatic hypotension.
• Risk with Severe Heart Conditions: Although Brimonidine tartrate eye drops generally have a minimal impact on blood pressure, care should be taken when using it by patients with serious heart diseases.
• Risk of Contamination in Eye Drops: Reports indicate a risk of bacterial keratitis from the use of multi-dose eye drop containers. Contamination typically occurs when used by patients with existing corneal diseases or damage to the eye’s surface layer.
• Ophthalmologic: If a person wears contact lenses, ensure to remove them before using your medication. Moreover, wait for 15 min before wearing contact lenses again.
• Multiple Eye Drops Users: When using more than one type of ophthalmic product, allow a 5-minute interval between each application.
• Drowsiness: This medication may make you tired or drowsy temporarily. In such situations, do not drive, use machines, or indulge in any activity that requires alertness. 
• Kidney & Liver Function: The use of Brimonidine eye drops by patients with kidney or liver problems has not been studied. If you have a history of such disease or have an impaired kidney or liver, talk to your doctor and discuss how the medication may affect you. 
• Orthostatic Hypotension: Many users may experience orthostatic hypotension. This condition, also known as postural hypotension, happens when there is a sudden drop in blood pressure while getting up from a lying position. People may experience this condition when using these eye drops. If you notice such a condition, talk to your doctor. In the meantime, try to avoid sudden movements and get up slowly from a lying or sitting position. 

What Precautions Should Be Taken When Using Brimonidine?

Before using Brimonidine P for ocular hypertension, you must be aware of certain precautions to avoid potential risks. Here are some important safety precautions that must be followed or considered while using these eye drops:

• If you have any known allergies to Brimonidine or any of the ingredients present in the medication, inform your doctor. The product may contain certain components that can cause severe allergic reactions. 
• Before considering treatment with this medication, share your complete medical history with your doctor. Doing so helps avoid the risk of potential side effects.
• If you are undergoing surgery or any other medical procedure, tell your surgeon about every product you are using. This includes prescription drugs, nonprescription medicines, and herbal supplements.
• If symptoms like itching, redness, swelling, or other irritations occur in your eyes, connect with your doctor immediately.
• If you or your child has an eye injury, develops an infection, or needs eye surgery, discuss it with a medical expert immediately. In such cases, discontinuation and modification of medication are required.
• Brimonidine P eye drops may cause some people to feel lightheaded, dizzy, drowsy, or fatigued. Avoid engaging in any potentially dangerous activities until you know how the medication affects you.
• These eye drops can increase the effects of alcohol and other CNS or central nervous system depressants, which include antihistamines, sedatives, pain relievers, seizure medications, muscle relaxants, and certain anesthetics. Consult your healthcare provider before using such antidepressants in combination with your eye drops.
• Brimonidine may increase your sensitivity to light. Wearing sunglasses and minimizing exposure to bright light may reduce discomfort.
• Pregnant ladies or those who are planning should not use these eye drops. Additionally, if you become pregnant while using these eye drops, stop using them and do not breastfeed.
• If you are using additional topical eye medications, apply them either 5 minutes before or 5 minutes after using Brimonidine eye drops.

What Are the Contraindications for Brimonidine P Eye Drops?

Brimonidine is contraindicated in the following conditions:

• Neonates and Infants: Brimonidine P is not recommended for use in newborns and infants under the age of 2 years.
• Hypersensitivity Reactions: It is not suitable for people who have previously shown an allergic reaction to any component of the medication.
• Patients on Monoamine Oxidase Inhibitors: Those undergoing treatment with MAO inhibitors are contraindicated from using Brimonidine P eye drops.

What If You Miss a Dose of Brimonidine P Eye Drops?

• If you forget the application of Brimonidine P eye drops, instill the missed dose when you remember. 
• If it is time for your next dose, you can continue your usual dosing schedule. 
• Remember to not take double doses just to make up for the previous one. 
• Use medication apps or set timers on your mobile devices to avoid skipping any doses.
• If you are still unsure, talk to your doctor.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult an expert or pharmacist.]

Can You Overdose on Brimonidine?

There is limited information about accidental ingestion of Brimonidine in adults. The only side effect reported to date was hypotension. There are even treatments for an oral overdose, which include- supportive and symptomatic therapy. These treatments involve the evacuation of the stomach during the first few hours of overdosage. Moreover, there are certain cases of overdoses that have been reported in infants and children using Brimonidine P for ocular hypertension. These symptoms include apnea, bradycardia, coma, lethargy, pallor, respiratory depression, and somnolence. If you are experiencing any such symptoms, contact your doctor right away or call 911.

[Note: If you consumed more than the recommended dose, get medical help right away or contact the Poison Help line at 1-800-222-1222.]

How To Store Brimonidine P Eye Drops?

To maintain the long-term effectiveness of any medicine, a proper environment is a must. If you plan to buy Brimonidine from Canada, follow the below storage instructions:

• Keep the medication in the container it came in and store it at a temperature between 15-25 °C in a dry place. Make sure that the container is out of reach of children and away from heat or moisture.
• Avoid disposing of the medicine by flushing it down in the toilet. 
• Always place safety lock caps to protect your children from poisoning. Ensure that the medication is in a safe location. 
• Check the packaging of your specific brand for storage instructions.
• You can also ask a medical expert for recommendations on how to store the medication.
• Discard the dropper when it is past its expiration date or is no longer required.

[Note: Discuss with your medical professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

What Are the Brimonidine P Interactions?

Like every other medication, Brimonidine P can have several interactions when combined with other drugs. Let’s take a look at these adverse interactions:

• Cardiac Glycosides: Since this drug is used to lower blood pressure, combining it with antihypertensives or cardiac glycosides should be done with caution.
• CNS Depressants: While specific interaction studies with Brimonidine P and CNS depressants (such as alcohol, barbiturates, opiates, sedatives, or anesthetics) have not been conducted, the risk for an additive effect in patients should be considered.
• Tricyclic Antidepressants: Tricyclic antidepressants are known to reduce the blood pressure-lowering effect of systemic clonidine. It is not known if the simultaneous use of these antidepressants with Brimonidine P affects its ability to lower intraocular pressure (IOP). Therefore, caution is recommended for patients using tricyclic antidepressants.
• Monoamine Oxidase Inhibitors: MAO inhibitors could theoretically impact the metabolism of Brimonidine, causing increased systemic effects, such as low blood pressure. Caution is advised for patients on MAO inhibitors due to these potential interactions.

What Are the Other Brimonidine P Interactions?

Other than the above drugs, Brimonidine has certain disease interactions. If you have any of the following medical conditions, talk to your medical provider before using this medication:

• Cardiovascular
• Depression
• Renal/liver

[Note: This isn’t a complete list, and there could be other medications that interact with Brimonidine P. Ensure to tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Drugs Can I Use Instead of Brimonidine?

Durg alternatives provide a convenient way for patients to switch from one treatment option to another. This choice is influenced by many factors, including when people are not getting the desired results. While many drug alternatives are available in the market, consulting a medical expert before using one is necessary. They will monitor your condition and determine the best possible drug substitute that suits your body’s needs. Some of the drugs that you can use in place of Brimonidine are as follows:

• Brimonidine ophthalmic
• Latanoprost ophthalmic
• Lumigan (bimatoprost)
• Timolol ophthalmic
• Xalatan

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Brimonidine P Cost & Coupons

Brimonidine is an effective ophthalmic medication used to treat eye conditions like glaucoma, but its high retail prices can be a concern for people across the US. To manage these expensive costs, many Americans choose reliable pharmacies like Polar Bear Meds to purchase medicines at affordable prices without needing any healthcare insurance plans. Moreover, the pharmacy also offers additional discounts to its customers for extra cost-savings. If you are a resident of the USA, don’t miss out on this opportunity. Buy Brimonidine with coupon code “WELCOMEPB10” and get an extra 10% on your first orders. Don’t sit back and get quality medications at reduced rates delivered directly from Canada. 

Frequently Asked Questions

What is the response time of Brimonidine P?

Alphagan P (Brimonidine) usually reduces eye pressure within 2 to 3 days as soon as you apply it. It works best when the medication is instilled 3 times a day. However, it is important to note that you are not taking an overdose of eye drops for effective results. Use it as prescribed by the healthcare provider.  

Why are Brimonidine P eye drops not recommended for children?

Due to their capacity to pass through the blood-brain barrier, causing central nervous system toxicity, these eye drops are not prescribed to children. As per the clinical reports of the National Library of Medicine, the medication may have severe side effects in infants, including bradycardia (slowed heart rate), hypotension (low blood pressure), and apnea (temporary cessation of breathing). Given these risks, the use of Brimonidine in pediatric patients is generally avoided, as its safety and effectiveness in young children have not been studied yet.

Is Brimonidine P and beta blockers the same thing?

No, they are not the same. Brimonidine is an alpha-2 (α2) adrenergic receptor agonist that works by lowering the fluid production in the eye and increasing fluid outflow. On the other hand, beta blockers lower blood pressure, thus helping reduce heart risks. However, a combination of both drugs, Brimonidine and a beta-blocker (timolol), is used to manage elevated IOP in patients with glaucoma.

Does Brimonidine P cause eyelash growth? 

Brimonidine does not make eyelashes grow. However, a different glaucoma medication called Bimatoprost, also known as Lumigan, is known to cause eyelash growth as a side effect. Lumigan is also marketed under the name Latisse, which is used specifically to improve the thickness, length, and darkness of eyelashes.

Does Brimonidine raise blood pressure?

Yes, Brimonidine may raise blood pressure in certain patients. This side effect is mostly reported among people who are older, female, and have conditions such as type 2 diabetes. This increase in blood pressure levels occurs due to the systemic absorption of the medication, which affects the cardiovascular system. If you noticed a significant increase in your blood pressure after using Brimonidine P eye drops for glaucoma treatment, consult your doctor right away. 

Does Brimonidine cause weight gain?

No, Brimonidine does not cause weight gain. However, patients using this medication having certain underlying conditions might notice weight gain. If you notice significant weight gain while using Brimonidine, it is important to discuss this with your doctor. They can evaluate your condition and check whether the medicine is likely the cause or not. 

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