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Cephalexin

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Product Details

What Is Cephalexin?

What Is Cephalexin?

Cephalexin is a prescription antibiotic medication used for the treatment of bacterial infections in both adults and pediatric patients. It belongs to the cephalosporin class of antibiotics and is commonly prescribed for skin, respiratory tract, ear, bone, and urinary tract infections caused by susceptible bacteria.

Cephalexin is available in multiple strengths and dosage forms and should always be taken under medical supervision. Our pharmacy currently offers Cephalexin 250 mg and 500 mg tablets, as well as 250 mg capsules. Many patients in the U.S. also choose licensed Canadian pharmacies to obtain Cephalexin while ensuring quality, authenticity, and cost savings.

Quick Facts About Cephalexin

Quick Facts About Cephalexin

FeatureDetails
Brand NameKeflex
Generic NameCephalexin
Drug ClassFirst‑generation cephalosporin antibiotic
FDA Approval StatusFDA‑approved (Initial U.S. approval: 1971)
FDA‑Approved Indications• Respiratory tract infections (e.g., streptococcal pharyngitis)
• Otitis media
• Skin and skin structure infections
• Bone infections (osteomyelitis)
• Genitourinary tract infections
Dosage FormsOral capsules, oral suspension, tablets
Available StrengthsCapsules: 250 mg, 500 mg
Suspension: 125 mg/5 mL, 250 mg/5 mL
Tablets: 250 mg, 500 mg
Boxed WarningNone
Common Side EffectsDiarrhea, nausea, vomiting, abdominal pain, rash
Serious Side EffectsSevere allergic reactions (anaphylaxis), Clostridium difficile–associated diarrhea, Stevens‑Johnson syndrome (very rare)
Use in BreastfeedingExcreted in breast milk; caution advised
Renal/Hepatic ImpairmentRenal impairment: dose adjustment required; monitor kidney function
StorageStore at 20–25°C (68–77°F), protect from moisture and direct sunlight
Prescription RequiredYes

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What is Cephalexin Used For?

What is Cephalexin Used For?

Cephalexin is FDA-approved for the treatment of the following bacterial infections caused by susceptible organisms:

  • Respiratory tract infections (streptococcal pharyngitis)
  • Skin and soft tissue infections
  • Bone infections (osteomyelitis)
  • Genitourinary tract infections, including uncomplicated urinary tract infections (UTIs)
  • Otitis media (middle ear infections)
Important Safety Information on Cephalexin (Keflex)

Important Safety Information on Cephalexin (Keflex)

Cephalexin tablets should be taken only under the supervision of a licensed healthcare provider. Misuse or inappropriate dosing may reduce effectiveness or increase the risk of side effects.

  • Serious allergic reactions may occur, especially in people with a history of penicillin or cephalosporin allergy.
  • Clostridium difficile–associated diarrhea (CDAD) has been reported with nearly all antibiotics, including Cephalexin. This may range from mild diarrhea to life‑threatening colitis.
  • Patients with kidney disease may require dose adjustment, as Cephalexin is primarily eliminated by the kidneys.
  • It should be used with caution in people who have a history of gastrointestinal disorders, particularly colitis.
  • Pregnant or breastfeeding women should discuss the use of Cephalexin with their pharmacist or provider before use. Cephalexin is excreted in breast milk.
  • Long-term use may result in overgrowth of nonsusceptible organisms, including fungi. Patients should be monitored for secondary infections.
  • Cephalexin may cause false‑positive results in certain urine glucose tests (using copper reduction methods). Clinicians should be aware of this possibility.
  • To reduce the development of drug‑resistant bacteria, Cephalexin should be used for infections proven or strongly suspected to be bacterial.
  • Cephalexin tablets and capsules are not effective against viral infections such as the common cold or flu.
What Is the Mechanism of Action of Cephalexin?

What Is the Mechanism of Action of Cephalexin?

Cephalexin works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) inside susceptible bacteria, disrupting the formation of the cell wall. This weakens the bacteria, leading to cell lysis and death, making Cephalexin effective against a range of bacterial infections.

How to Properly Take Cephalexin?

How to Properly Take Cephalexin?

Follow these Cephalexin tablets and capsules administration guidelines for the safe and effective use:

  • Cephalexin tablets or capsules may be taken with or without food. Taking them with food might help reduce stomach upset.
  • Take Cephalexin at evenly spaced times each day to maintain consistent levels in your body.
  • Swallow whole with a full glass of water; do not crush or chew unless advised.
  • Complete the full prescribed course, even if symptoms improve early, to prevent antibiotic resistance.
  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one.
  • Do not take two Cephalexin doses at the same time to make up for a missed dose.
What Are the Side Effects of Cephalexin?

What Are the Side Effects of Cephalexin?

Common Side Effects of CephalexinRare or Serious Side Effects of Cephalexin
Skin rashSevere allergic reactions (anaphylaxis, swelling of face/lips/tongue)
ItchingClostridioides difficile–associated diarrhea (severe or bloody diarrhea)
NauseaSeizures (rare, mainly in patients with kidney impairment)
VomitingSevere skin reactions (Stevens–Johnson syndrome: very rare)
DiarrheaLow white blood cell or platelet counts (rare blood disorders)

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Pros and Cons of Cephalexin

Pros and Cons of Cephalexin

Pros

  • FDA‑approved for common bacterial infections (respiratory tract, skin/soft tissue, bone, urinary tract, otitis media)
  • Suitable for adults & pediatric patients, including infants when dosed appropriately
  • Generally well tolerated when used as prescribed
  • Available in multiple strengths and dosage forms

Cons

  • Limited effectiveness against certain Gram‑negative organisms and resistant strains
  • Risk of allergic reactions, especially in patients with penicillin or cephalosporin allergy
  • May cause Clostridioides difficile–associated diarrhea, which can be severe
  • Requires dosing every 6–12 hours, which may be inconvenient
  • Dose adjustment is needed in people with kidney disease
  • Misuse or incomplete courses can promote antibiotic resistance
  • Not effective against viral infections (flu or colds)
What Happens If You Take Too Much Cephalexin?

What Happens If You Take Too Much Cephalexin?

Taking too much Cephalexin can increase the risk of side effects and toxicity, especially in people with kidney impairment. Symptoms of Cephalexin overdose may include severe nausea, vomiting, diarrhea, and stomach pain. In rare cases, seizures may occur, particularly with very high doses or reduced kidney function.

If a cephalexin overdose is suspected, seek immediate medical attention or contact the poison control center immediately. Do not try to handle it on your own, and do not wait for Cephalexin overdose symptoms to get worse.

Cephalexin Tablets & Capsules Dosage Guide

Cephalexin Tablets & Capsules Dosage Guide

Cephalexin (Keflex) dosage depends on the type and severity of infection, patient age, and kidney function. Follow this Cephalexin dosing schedule for different medical conditions:

IndicationTypical Adult DosagePediatric DosageNotes
Respiratory Tract Infections250–500 mg every 6 hours25–50 mg/kg/day in divided dosesAdjust based on severity; complete the full course.
Skin & Soft Tissue Infections250–500 mg every 6 hours25–50 mg/kg/day in divided dosesCommonly used for cellulitis and skin infections.
Bone Infections (Osteomyelitis)500 mg every 6 hours; maximum daily dose should not exceed 4 g/day25–50 mg/kg/day in divided dosesLonger treatment duration is often required.
Genitourinary Tract Infections (UTIs)250–500 mg every 6–12 hours25–50 mg/kg/day in divided dosesEffective for uncomplicated UTIs.
Otitis Media (Ear Infections)250–500 mg every 6 hours25–50 mg/kg/day in divided dosesOral suspension is commonly used in children.
Maximum Daily DoseUp to 4 g/dayUp to 100 mg/kg/day (max 4 g/day) for severe infections onlyDo not exceed the recommended maximum.

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How Should Cephalexin Be Stored?

How Should Cephalexin Be Stored?

Follow these storage guidelines for effective use of Cephalexin:

  • Cephalexin should be kept at 20–25°C (68–77°F), away from extreme heat or cold.
  • It must be stored in a dry place, away from bathrooms and other damp areas.
  • Store Cephalexin in its original container to protect it from light and moisture.
  • Keep it out of reach of children and pets to prevent accidental ingestion.
  • Do not use expired medication. Always check the expiration date before taking this medication.
  • Reconstituted oral suspension should be refrigerated and discarded after 14 days.
What Medications Should Not Be Taken with Cephalexin?

What Medications Should Not Be Taken with Cephalexin?

Cephalexin may interact with other medicines. It is important to inform your healthcare provider about all prescription drugs, OTC medicines, and supplements before starting treatment.

Interacting Medication/ClassExamplesPotential Effect
ProbenecidIncreases cephalexin blood levels by reducing renal excretion, which may increase the risk of side effects
MetforminIncreased metformin blood concentrations have been reported; monitor blood glucose and kidney function
Live Bacterial VaccinesOral typhoid vaccineReduced effectiveness of the vaccine due to antibiotic interference
Anticoagulants (Rare)WarfarinMay increase anticoagulant effects, leading to an increased risk of bleeding; monitor INR
Nephrotoxic DrugsAminoglycosides, loop diureticsIncreased risk of kidney toxicity, especially in patients with pre‑existing renal impairment

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What Is an Alternative to Cephalexin?

What Is an Alternative to Cephalexin?

If Cephalexin is unavailable, other prescription medications may be used under medical supervision. Some of the Cephalexin alternatives include:

  • Duricef (Cefadroxil)
  • Ceftin (Cefuroxime)
  • Omnicef (Cefdinir)
  • Suprax (Cefixime)
  • Rocephin (Ceftriaxone)
Why Buy Cephalexin Online from Polar Bear Meds?

Why Buy Cephalexin Online from Polar Bear Meds?

Many patients buy Cephalexin from Canada because it offers a convenient & reliable way to access genuine, prescription medication. When you order Cephalexin online from Polar Bear Meds, you can expect high-quality medications sourced from licensed Canadian pharmacies. Every order is carefully reviewed for accuracy and requires a valid prescription, ensuring both safety and compliance. Once processed, your medication is shipped quickly and securely, usually arriving within 3–5 business days via Xpress Post.

Cephalexin Coupons and Savings Options

  • For added savings, use the coupon code ‘WELCOMEPB10’ at checkout to get 10% off your first order.
  • Save up to 70–80% on your antibiotics compared to typical U.S. retail rates.
  • Existing customers can earn a $20 credit for each friend they refer.
  • Price match guarantee for the same medication, strength, and quantity, helping ensure competitive pricing.
Important Disclaimer

Important Disclaimer

The information provided above about Cephalexin is for general educational purposes only. The content on this page is not intended to replace any kind of professional advice, diagnosis, or treatment. Cephalexin is a prescription-only medicine and should be used strictly under the guidance of a licensed healthcare provider in the U.S. Do not start, stop, or change the dosage of this medication without consulting your doctor.

Cephalexin FAQs

Cephalexin FAQs

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