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Diphenhydramine

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Product Details

Description

Diphenhydramine is a first-generation antihistamine primarily indicated to treat symptoms of allergies and hay fever. It also helps with short-term sleep issues and motion sickness, and may assist with certain movement disorders like Parkinson’s disease. Unlike newer antihistamines, Diphenhydramine can cross the blood-brain barrier, leading to its sedative effects. While effective, it should be used with caution, particularly in elderly individuals, due to an increased risk of cognitive decline and anticholinergic side effects. Caution is also advised when combining it with other central nervous system depressants, such as alcohol or sedatives. You can buy Diphenhydramine online from Canada using a valid doctor’s prescription.

Generic NameDiphenhydramine
Brand NameBenadryl or Diphen
FormsOral Capsules
Strengths Available25 mg & 50 mg
Packaging
Requires PrescriptionPrescription only (Rx)
Ships to USAYes
Uses and Benefits

You can buy Diphenhydramine medication online to treat:

  • Certain allergy or common cold symptoms
  • Hay fever
  • Allergic reactions
  • Motion sickness
  • Trouble sleeping
  • Certain movement problems

Benefits of Diphenhydramine

  • It effectively provides relief from allergic rhinitis and alleviates symptoms of insect bites and hives by reducing itching and swelling.
  • Diphenhydramine can also be used for Parkinson’s disease to help manage certain symptoms.
Dosage

The recommended dosage of Diphenhydramine tablets varies from patient to patient and is based on the patient's age and medical condition. The dose provided here is general, and if your doctor has recommended a different dose for you, follow their instructions. Typical Diphenhydramine dosage includes:

Dosage of Diphenhydramine for Allergic Reactions & Cold Symptoms

  • Adults: Diphenhydramine dosage for adults is 25-50 mg every 4-6 hours (max 300 mg/day).

Children

  • Under 6 years: Not suggested for use unless prescribed by a doctor.
  • Aged 6-12: 12.5-25 mg every 4-6 hours (max 150 mg/day).
  • Aged 12+: Same as adult dosage.

Dosage of Diphenhydramine for Insomnia

  • Adults: 50 mg once at bedtime.

Dosage of Diphenhydramine for Motion Sickness

  • Adults: 25-50 mg every 4-6 hours (max 400 mg/day).
Usage Guide

Before using Diphenhydramine, refer to the patient information leaflet and medication guide and follow your doctor’s instructions closely to ensure a safe & effective use.

  • Take Diphenhydramine for hives or insomnia with or without food, accompanied by a glass of water. You can take it with food if you experience stomach discomfort.
  • This sleep aid medication is usually to be taken 3-4 times daily, depending on your dose.
  • Do not use this medication as a sleep aid for children under 12 years of age.
  • If you are using Diphenhydramine for motion sickness, take it 30 minutes before moving.
  • Call your doctor if your condition does not improve or worsens after a week of taking it.
How It Works

Diphenhydramine functions by blocking histamine receptors, which are natural substances in the body that play an important role in immune responses. This drug targets H1 receptors specifically, preventing histamine from causing symptoms such as sneezing, itching & swelling. Additionally, it blocks acetylcholine receptors, which contributes to its sedative effects and can help with motion sickness. It can also help alleviate symptoms of Parkinson’s disease by reducing involuntary movements.

Side Effects

Common Diphenhydramine side effects may include:

  • Dizziness
  • Drowsiness
  • Upset stomach
  • Excitability in children

Serious side effects (rare):

  • Severe allergic reactions
  • Seizures
  • Urinary retention

Note: Call your healthcare provider if you experience any serious symptoms or unusual changes.

Warnings

There are specific warnings that users should be aware of while using Diphenhydramine for insomnia and other conditions. Key warnings include:

  • Allergy: You should not take Diphenhydramine if you have an allergy to Benadryl or any of the ingredients present in Diphenhydramine. If you experience any hypersensitivity reaction, contact your doctor.
  • Photosensitivity: Diphenhydramine can increase your skin's sensitivity to sunlight. Avoid sunlamps or tanning booths while using this product.
  • Persistent Cough: Discontinue use of this medication and contact your doctor if you experience a cough that lasts more than 7 days or returns after initially resolving. Also inform them if you have a cough accompanied by fever, rash, or headache, as these could indicate a serious condition.
  • Alcohol Use: Avoid alcohol while using Diphenhydramine, as it may intensify drowsiness and increase the risk of side effects.
Safety Guide

Before taking Diphenhydramine, certain precautions should be considered to ensure safe & effective use of Diphenhydramine for itchy skin and other symptoms.

  • Pregnancy: It is still unknown if this medication can affect your pregnancy or fetus. Inform your doctor if you are pregnant, plan to get pregnant, or suspect a pregnancy.
  • Breastfeeding: You should not take Diphenhydramine if you are breastfeeding an infant unless instructed otherwise by your doctor.
  • Blurred Vision: This medication can affect your vision or alertness. Do not drive a vehicle, use machinery, or engage in other tasks that require clear vision or coordination until you determine how it affects you.

Geriatric or Pediatric Patients: Elderly patients or individuals less than 18 years of age are at an increased risk of specific side effects linked with the use of Diphenhydramine.

Missed Dose

If you have missed a dose of Diphenhydramine, take it as soon as you remember, unless it is almost time to take your next dose. If the time for your next dose is almost here, skip the missed dose and resume your regular dosing regimen. Never take an extra dose of the same medication to make up for a missed dose.

Overdose

If you or someone has overdosed on Diphenhydramine, you should seek medical assistance promptly by calling the poison control helpline. If your symptoms are severe, you can also go to the nearest medical care center.

Storage Guide

Follow proper storage instructions to maintain the potency of the medication you are using. For Diphenhydramine, consider the following:

  • Store Diphenhydramine oral capsules at a controlled room temperature, at 68°F-77°F (20°C-25°C).
  • Keep Diphenhydramine away from the sight and reach of children & pets to avoid accidental ingestion.
  • Do not keep medications that are no longer needed or have expired. Dispose of them safely to prevent environmental contamination.
Interactions

Certain medications may interact with Diphenhydramine and affect how it works. Tell your doctor about all the drugs you are using, including all prescription, over-the-counter drugs, herbs, and supplements you are currently using or plan to use. Some potential Diphenhydramine interactions include:

  • Alcohol
  • Zolpidem (Ambien)
  • Eszopiclone (Lunesta)
  • Duloxetine (Cymbalta)
  • Escitalopram (Lexapro)
  • Metoprolol
  • Tramadol
  • Acetaminophen (Tylenol)
  • Cetirizine (Zyrtec)
  • Baclofen
Alternatives

Although Diphenhydramine is effective for many, alternatives may be necessary for individuals with unique health needs. Consult your doctor before switching or starting a new prescription. Alternatives to Diphenhydramine include:

  • Cetirizine
  • Fexofenadine
  • Loratadine
  • Xyzal (levocetirizine)
Cost & Coupons

Why Buy Diphenhydramine from Polar Bear Meds?

At Polar Bear Meds, we’re dedicated to making prescription medications, such as Diphenhydramine oral tablets, more accessible and affordable for our customers in the United States. Our prices are significantly lower than typical USA pharmacy retail rates without compromising on safety or quality. Every order is sourced exclusively from licensed and trusted pharmacies and undergoes complete prescription verification to ensure compliance and authenticity. We offer discreet, trackable shipping to all states in the USA, along with refill support for ongoing treatment. Our helpful and friendly customer service team is always here to assist you every step of the way.

Cost & Coupons

Order Diphenhydramine from Canada and have it delivered straight to your doorstep hassle-free in the USA. You can also save more by using the discount coupon “WELCOMEPB10” to get an extra 10% off on your first purchase. There are no hidden handling or processing fees, as we believe in complete transparency. Looking to save even more? Join our referral program and get a $20 credit every time you refer a friend or a family member. Your referral will also get a $20 credit, making it a win-win for everyone. Additionally, after referring every 10 verified customers, you'll receive a $100 credit to your account as our way of saying thank you for spreading the word.

FAQ

Guarantee

AtPolar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently buy Diphenhydramine from Canada at a substantial cost, call us at 1-888-779-2193 toll-free.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn

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