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Aluminum Chloride Hexahydrate

DrySol Anti-Perspirant 20%

DrySol Anti-Perspirant, containing aluminum chloride hexahydrate, is a topical antiperspirant designed and approved by the FDA to treat hyperhidrosis or excessive sweating. This condition affects various body parts, such as the underarms, palms, and soles of the feet. Initially, DrySol is applied daily to the affected areas until a reduction in sweating is observed. Once effective control is achieved, application frequency is reduced to once or twice a week. While DrySol is effective in managing sweat production, it can cause side effects such as burning, itching, prickling, or tingling sensations in the treated areas. These reactions are typically localized to the areas where the medication is applied. Users should avoid applying on broken or irritated skin and near eyes. It’s important to consult healthcare providers before use, especially during pregnancy or while breastfeeding, and in case of pre-existing medical conditions.

Product Overview

DrySol Anti-Perspirant is a topical solution designed to combat hyperhidrosis, a condition characterized by excessive sweating. The active ingredient, aluminum chloride hexahydrate, works by blocking the sweat glands, significantly reducing sweat production. Typically, DrySol is applied to areas most affected by excessive sweating, such as the underarms, palms, and soles of the feet. The recommended initial treatment involves applying DrySol nightly at bedtime, allowing it to work overnight. After a few days of controlled sweating, the frequency of application can be reduced to once or twice a week.

The use of DrySol is generally safe, but it may cause side effects such as itching, redness, and skin irritation. More severe reactions, like respiratory issues or swelling, require immediate medical attention. It is crucial to avoid applying DrySol on broken or freshly shaved skin to prevent irritation, and it should not come into contact with eyes or other sensitive areas. Pregnant or breastfeeding women should use DrySol cautiously and only under medical advice. Individuals with certain medical conditions, particularly those affecting the kidneys or liver, should also consult a healthcare provider before use.

DrySol might interact with other topical products, especially those containing similar active ingredients, potentially leading to increased skin irritation. Therefore, it’s advisable not to use other antiperspirants or deodorants in the same area. While DrySol Anti-Perspirant is an effective solution for managing excessive sweating, its use must be carefully managed to avoid complications, and it should always be used as directed by a healthcare professional.

Uses of DrySol Anti-Perspirant

  • DrySol is primarily used as an antiperspirant for treating hyperhidrosis, a condition commonly known as excessive sweating.

How to Use DrySol Anti-Perspirant?


It comes in the form of liquid and has three strengths:

  • Bottle 35ML of 20%
  • Bottle 37.5ML of 20%
  • Bottle 60ML of 20%

Recommended Dosage of DrySol Anti-Perspirant 20%

Dosage for DrySol (aluminum chloride hexahydrate 20%):

  • Preparation: Ensure that the area where you intend to apply DrySol is completely dry before application.
  • Initial Dosage: Apply DrySol to the affected area once daily at bedtime. This allows the medication to work overnight without interruption.
  • Morning Routine: The morning after each application, wash the treated area with soap and water to remove any residue.
  • Maintenance Dosage: After applying DrySol daily for the first three days, reduce the frequency of application to once or twice a week, depending on your needs and as directed by your healthcare provider.

This regimen helps manage excessive sweating effectively while minimizing skin irritation.

[Note: Remember these recommendations may vary depending on person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Take It?

Topical Application Method:

  • This medication is for external use only. Apply it directly to your skin.
  • Avoid contact with cuts or wounds. If it accidentally touches these areas, wash it off immediately.
  • Be careful to keep it away from your eyes, nose, and mouth.

Directions for Use:

  • Your doctor will advise you on the amount of medicine to use. Always follow their instructions and do not apply more than recommended.
  • Typically, you should apply DrySol at bedtime. This ensures it won’t be washed off during bathing or showering.
  • If you are using DrySol without a doctor’s prescription, strictly adhere to the instructions on the product label.

Repeat Application Instructions:

  • Apply the medicine at bedtime, unless advised otherwise by your doctor, to ensure it remains effective even after bathing or showering.
  • Use this medication strictly on your skin. If it comes into contact with any cuts or scrapes, rinse it off immediately.
  • Ensure that it does not get into your eyes, nose, or mouth.
  • Follow the prescribed or labeled dosage instructions closely and never use more than directed.
  • For non-prescription use, always follow the label instructions carefully.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does DrySol Anti-Perspirant Work?

DrySol, containing aluminum chloride hexahydrate, is a topical medication applied to the skin. Although the precise mechanism of action is not fully understood, it is believed that the aluminum in the medication interacts with the body to form a plug made up of aluminum and nearby skin cells over the sweat ducts. This plug effectively reduces the amount of sweat released from these ducts. As new skin cells develop in the treated area, these sweat glands gradually reopen, allowing average sweat production to resume.

Important Safety Information

Side Effects

Common side effects of DrySol Anti-Perspirant may include:

  • Itching
  • Rash
  • Skin irritation

Mild side effects of DrySol Anti-Perspirant may include:

  • Redness
  • Dryness 
  • Mild skin irritation

If you experience any of the following serious side effects after using this product, discontinue use immediately and seek medical assistance:

  • Respiratory Issues, including breathing difficulties or wheezing.
  • Cardiac Symptoms (an unusually fast heartbeat)
  • General Discomfort including fever or a feeling of overall illness.
  • Swelling (enlarged lymph nodes or swelling of the lips, face, tongue, mouth, or throat)
  • Digestive Symptoms include vomiting, nausea, or stomach cramps.
  • Skin Reactions like Itching, rash, or hives (pale red bumps on the skin).
  • Neurological Symptoms such as feeling lightheaded, dizziness, or fainting.
  • Difficulty swallowing due to joint pain or throat tightness.

This medication can sometimes trigger serious allergic reactions, and these symptoms require immediate medical attention to prevent further complications. 

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]


Before using DrySol Anti-Perspirant, it’s crucial to be aware of the following warnings to ensure safe and effective use:

  • For External Use Only: DrySol Anti-Perspirant is formulated for topical application only. It should never be ingested or used in any way other than as directed on the product label. Accidental ingestion can lead to severe adverse effects and requires immediate medical attention.
  • Avoid Contact with Eyes: Take extra caution to prevent DrySol Anti-Perspirant from getting into your eyes. If accidental eye contact occurs, immediately flush your eyes with plenty of water and seek medical advice if irritation persists.
  • Discontinue Use if Irritation Occurs: While DrySol Anti-Perspirant is generally well-tolerated, some individuals may experience skin irritation or sensitivity. If you notice any signs of irritation, such as redness, burning, or itching, discontinue use immediately and consult your healthcare provider.
  • Not for Use on Broken or Irritated Skin: DrySol Anti-Perspirant should not be applied to areas with broken or irritated skin, as this may increase the risk of adverse reactions and potentially lead to further irritation or infection.
  • Avoid Excessive Use: Follow the usage instructions carefully and do not apply DrySol Anti-Perspirant more frequently or in larger amounts than recommended. Excessive use can increase the risk of side effects and may not provide additional benefits.
  • Keep Out of Reach of Children: As with any medication or personal care product, it is essential to keep DrySol Anti-Perspirant out of reach of children to prevent accidental ingestion or misuse.
  • Consult Your Healthcare Provider: If you have any pre-existing medical conditions, are pregnant or breastfeeding, or are taking any medications, it is advisable to consult with your healthcare provider before using DrySol Anti-Perspirant to ensure its safety and appropriateness for your individual circumstances.

By carefully following these warnings and instructions, you can help ensure the safe and effective use of DrySol Anti-Perspirant for managing excessive sweating.


  • Skin Condition: Do not apply DrySol to broken, irritated, or recently shaved skin to avoid aggravation.
  • Reaction: If irritation or sensitization occurs, stop using the product immediately.
  • Application: This product is for external use only. Be sure to avoid contact with eyes.
  • Damage to Materials: Be cautious, as DrySol may damage certain metals and fabrics.
  • Fire Hazard: The product is flammable. Do not use it near an open flame.
  • Pregnancy: Use DrySol with caution during pregnancy only if the potential benefits justify the potential risks. While animal studies have shown risks, there are no conclusive human studies.
  • Breastfeeding: It is not known whether DrySol passes into breast milk. If you are breastfeeding, use this product with caution.


  • Do not use this medication if you are allergic to aluminum chloride, as it can cause a severe allergic reaction. 

Missed Dose

  • If you miss a dose of DrySol, apply it as soon as you remember.
  • However, if it is almost time for your next scheduled dose, skip the missed dose. Continue with your regular dosing schedule.
  • Do not apply a double dose or extra doses to make up for the missed one.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]


An overdose of DrySol Anti-Perspirant is generally not considered dangerous. However, if the medication is accidentally ingested, seek emergency medical help or call the Poison Help line at 1-800-222-1222 or call 911 immediately.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]


  • Be aware that the medicine will evaporate quickly if exposed to air.
  • Keep the medicine in a tightly sealed container.
  • Place it away from any sources of heat or open flames, as this medicine contains alcohol and is flammable.
  • Store your medication at room temperature.
  • Consult your pharmacist or doctor for proper disposal methods for the container and any unused or expired medicine.
  • Ensure that all medicine is kept out of reach of children.
  • Do not share your medicine with others.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

DrySol Anti-Perspirant Interactions

When using DrySol Anti-Perspirant, it’s important to be aware of potential interactions with other products or substances to ensure its safe and effective use. While DrySol Anti-Perspirant is generally well-tolerated, certain interactions may occur, and precautions should be taken.

  • Interactions with Other Topical Products: DrySol Anti-Perspirant should not be used in combination with other topical products containing aluminum chloride or aluminum zirconium compounds, as this may increase the risk of skin irritation or other adverse reactions. It’s advisable to avoid applying other deodorants, antiperspirants, or topical medications to the same area where DrySol Anti-Perspirant has been applied.
  • Interactions with Shaving: It’s recommended to apply DrySol Anti-Perspirant after shaving to avoid potential irritation or discomfort. Shaving immediately before applying the product may increase the risk of skin irritation or sensitivity.
  • Interactions with Clothing and Fabrics: DrySol Anti-Perspirant may cause discoloration or staining of certain fabrics, particularly those made of silk, nylon, or synthetic materials. To minimize this risk, it’s essential to allow the product to dry completely before dressing and to avoid contact with clothing until it has fully absorbed into the skin.
  • Interactions with Certain Medical Conditions: Individuals with certain medical conditions, such as kidney or liver disease, may need to exercise caution when using DrySol Anti-Perspirant. It’s advisable to consult with a healthcare professional before using the product if you have any pre-existing medical conditions.
  • Interactions with Medications: While DrySol Anti-Perspirant is unlikely to interact with most medications, it’s always recommended to inform your healthcare provider about all the medications and supplements you are taking before using any new product, including DrySol Anti-Perspirant.

By being aware of these potential interactions and taking the necessary precautions, you can help ensure the safe and effective use of DrySol Anti-Perspirant for managing excessive sweating. If you have any concerns or questions, it’s best to consult with a healthcare professional for personalized advice.

[Note: This isn’t a complete list, and there could be other drugs that interact with DrySol Anti-Perspirant. Make sure to tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

DrySol Anti-Perspirant Alternatives

  • Certain Dri (aluminum chloride hexahydrate)
  • Dry+ (aluminum chloride hexahydrate)
  • Qbrexza (glycopyrronium tosylate)
  • Glycopyrrolate (glycopyrrolate)
  • Oxybutynin (oxybutynin)
  • Botox (botulinum toxin type A)
  • Dysport (botulinum toxin type A)
  • Xeomin (botulinum toxin type A)
  • Robinul (glycopyrrolate)
  • Ditropan (oxybutynin)
  • Oxytrol (oxybutynin)
  • Antihydral
  • Drysol (different from DrySol) (aluminum chloride hexahydrate)
  • Sweatblock
  • Maxim
  • Perspirex
  • Hydrosal
  • Driclor (aluminum chloride hexahydrate)
  • Odor-X

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Frequently Asked Questions

Is DrySol Anti-Perspirant 20% good for armpits?

DrySol is highly effective for reducing underarm sweat. It contains Aluminum Chloride Hexahydrate (ACH), a powerful topical antiperspirant ingredient. Studies have shown that a 20% concentration of ACH in DrySol can control underarm sweating with a proven efficacy of 98%. Additionally, it can reduce the amount of sweat by up to 30%. This makes DrySol a strong choice for managing excessive underarm perspiration.

Are you supposed to use DrySol Anti-Perspirant everyday?

You should not use DrySol every day. Instead, apply a thin layer of the medication to the affected area as instructed by your doctor. Typically, it’s used once daily at bedtime for the first 2 to 3 days to control excessive sweating. Once the sweating is under control, you should reduce the application to just once or twice a week.

How quickly does DrySol work?

DrySol works quite rapidly for many users, with some experiencing desired results after just the first application. Others may require a couple more applications over the following nights to see similar effects. Individual responses can vary, but overall, feedback on DrySol’s effectiveness is overwhelmingly positive, with many users reporting significant improvements in controlling excessive sweating.

Do you put deodorant on after DrySol Anti-Perspirant 20%?

When using DrySol, you should not apply other deodorants or antiperspirants. DrySol can be used on various areas like the underarms, feet, hands, and scalp. After applying DrySol at night, it is important to wash it off in the morning with soap or shampoo. This helps to prevent any potential skin irritation.

How do you stop burning from DrySol?

If you experience burning sensations after you apply DrySol, immediately wash the affected area with soap and water. This discomfort may occur if the product is used on broken or recently shaved skin, applied to moist or damp skin, or if the concentration of the product is too strong. To avoid further irritation, discontinue use and consult your healthcare provider. They may advise you to wait until your skin has fully healed or dried before reapplying DrySol, or they might recommend using a lower-strength version of the product.

Does DrySol help with odor?

Yes, DrySol Anti-Perspirant 20% (aluminum chloride hexahydrate) can help with odor. Body odor occurs when sweat produced by your body mixes with bacteria on your skin. By effectively blocking the sweat ducts, DrySol prevents sweat from reaching the surface of your skin, thereby reducing the potential for odor development. This makes it an effective solution for controlling both sweat and associated body odor.

Does DrySol Anti-Perspirant 20% expire?

Yes, DrySol Anti-Perspirant 20% does have an expiration date, and it is vital to adhere to it. Using DrySol after this date may result in decreased effectiveness of the medication, and it may not perform as expected in controlling sweat. Additionally, using expired medications can sometimes be harmful. Always check the expiration date of your product to ensure its efficacy and safety.

Our Guarantee

At, we assure you the most affordable price to buy DrySol Anti-Perspirant online from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently access DrySol Anti-Perspirant 20% to treat your hyperhidrosis (excessive sweating) at a substantial cost, call us at 1-888-779-2193 toll-free.


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