Galcanezumab

Emgality Auto-Injector Prefilled Syringe 

Emgality Auto-injector, also known as Galcanezumab, belongs to a class of medications called monoclonal antibodies. It is used to prevent migraines & treat episodic cluster headaches. It is available in two strengths: 100mg/ml and 120mg/ml, provided as single-dose prefilled syringes and pens. The dosage of the medication is based on your condition and your body’s response to treatment. Galcanezumab works by binding to and blocking the calcitonin gene-related peptide (CGRP), which plays a crucial role in the pain cascade associated with migraines. Consult your healthcare provider with concerns or questions regarding Emgality’s usage, dosage, and storage. You can buy Emgality Auto injector online from trusted sources to ensure your medication is authentic and genuine. 

Product Overview

Emgality Auto-injector, containing the active ingredient galcanezumab, is a monoclonal antibody used to prevent migraines and treat episodic cluster headaches. Galcanezumab works by binding to and blocking the calcitonin gene-related peptide (CGRP), which plays a crucial role in the pain cascade associated with migraines. Emgality is available in two strengths: 100mg/ml and 120mg/ml, provided as single-dose prefilled syringes and pens. For migraine prevention in adults, the initial dose is 240 mg administered subcutaneously as two consecutive 120 mg injections, followed by a maintenance dose of 120 mg monthly. 

For episodic cluster headache treatment, the recommended dose is 300 mg at the start of the cluster period, which is continued monthly until the period ends. This medication is suitable for adults but is contraindicated for individuals under 18 years, those with severe cardiovascular disease, and those with severe renal or hepatic impairment. Common side effects of Emgality Auto-injector may include injection site reactions, constipation, vertigo, and nausea. Adverse side effects, such as serious allergic reactions and cardiovascular events, require immediate medical attention. 

Before using Emgality, inform your doctor about any allergies or medical conditions. If you miss a dose, take it as soon as you remember unless it’s close to the next dose. In case of an overdose of the medication, seek emergency medical help. Store Emgality in the refrigerator between 2°C-8°C (36°F-46°F) and do not freeze. It can be kept at room temperature for up to seven days. Use each auto-injector only once and dispose of it properly. Consult your healthcare provider for concerns or questions regarding Emgality’s use and storage.

What Is the Emgality Injection Used For?

It is used to prevent and treat:

• Migraines 
• Episodic cluster headache

What Are the Formulations & Strengths of Emgality Auto-injector?

Emgality Auto-injector comes in two forms with strengths of 100mg/ml and 120mg/ml: 

• Single-dose prefilled syringes
• Single-dose prefilled pen

What Is the Recommended Dosage of Emgality Auto-injector?

The recommended dosage of Emgality Auto-injector can vary from individual to individual, usually based on the medical condition being treated, its severity, and other factors. The following dosage recommendation includes the dosage that is commonly prescribed. However, be sure to follow your doctor’s instructions. If they have recommended a different dose, follow it and do not make dosage alterations without consulting them first, as it can cause unwanted side effects. 

For Migraine Prevention 

• The initial recommended dose of Emgality Auto-injector for adults is 240 mg administered subcutaneously as two consecutive doses of 120 mg.
• The maintenance dose for adults is 120 mg, administered as a subcutaneous injection once monthly. 

For Treatment of Episodic Cluster Headache

• At the onset of the cluster period, an adult should take 300 mg of Emgality Auto-injector. 
• Subsequent doses of Emgality Auto-injector are 300 mg once every month until the end of the cluster period. 

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Inject Emgality Auto-injector?

Before using the Emgality Auto-injector, carefully read and follow the instructions for use in the patient information leaflet that came with your prescription. Ask your doctor or pharmacist if you have any questions or concerns regarding the medication’s use. The medication is administered subcutaneously. Make sure you and your caregiver understand how to properly inject and handle the Emgality Auto-injector. You can refer to the guidelines given below or ask your doctor if you have any doubts.

• This medication is taken as a subcutaneous injection once every month. When you first receive your prescription for Emgality Auto-injector, your doctor or healthcare provider will explain how to inject the medication by yourself. 
• The first time you inject Galcanezumab subcutaneously, you may do it at your doctor’s office or in your home. You will need to give yourself two or three separate subcutaneous injections. After that, to prevent migraine headaches, you will give yourself one injection at home every month. To treat cluster headaches, you will give yourself three injections every month. 
• Emgality is available in two forms: single-dose prefilled syringes and pens. Both forms contain only one dose and are meant to be used once and disposed of. 
• Before using this medication, take it out of the refrigerator and let it warm for at least thirty minutes. Do not warm it in any other way, such as in the microwave or hot water. 
• Before using Emgality, check the product for any visual appearance. Do not use it if it has particles in it or is discolored. If either visual change is present, do not use the product. 
• Do not shake or freeze the Emgality Auto-injector. 
• Before injecting your prescribed dosage, you should clean the injection site with rubbing alcohol. Rotate the injection site every time you inject the medication subcutaneously. 
• You should not inject the medication where your skin is damaged, torn, tender, red, or hard. Also, avoid injecting in sites that have stretch marks or scars. 
• Inject the Emgality Auto-injector under the skin of your abdomen, front thighs, lower arms, or buttocks exactly as directed by your doctor. 
• The dosage of the medication is based on the condition being treated & the body’s response to treatment. 
• Use the Emgality Auto-injector regularly to get the most benefit from it. 
• Let your doctor know if your condition does not get better or if it gets worse.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Emgality Auto-injector Work?

Emgality (galcanezumab) is a monoclonal antibody that prevents migraines and cluster headaches by binding to calcitonin gene-related peptide (CGRP). It blocks CGRP from attaching to its receptors, disrupting the pain cascade. Administered monthly, Emgality maintains consistent levels in the bloodstream, providing ongoing prevention. This approach aims to reduce headache frequency, severity, and duration, potentially improving the quality of life for sufferers.

Important Safety Information for Using Emgality Auto-injector

What Are the Side Effects of Emgality Auto-injector?

Common side effects of Emgality Auto-injector: Similar to other medications, Emgality Auto-injector can also cause certain side effects in some users. These effects typically last for a short time and usually resolve on their own within a few days or weeks as your body adapts to the medication. If they continue or worsen, consult your doctor. Your doctor prescribed this medication to you after determining that its benefits outweigh the risks associated with its use. If you are concerned about the risks associated with use, talk to your doctor. They will help you prevent and manage them. Common side effects of Emgality Auto-injector may include: 

• Injection site reactions like redness, pain, and itching: Similar to other injectable medications, injection site reactions are a common side effect of Emgality. These reactions are not usually severe or lasting and disappear in a few days or weeks. If they are severe or persistent, talk to your doctor. To prevent injection site reactions, you should rotate the injection site area each time you inject the medication. 

• Discoloration of the skin: When administered subcutaneously, this medication can change your natural skin tone at the injection site. It can cause redness, bruising, and discoloration due to irritation of the skin and underlying tissues, which can further manifest itself as discoloration of the skin at the injection site area. 

• Common cold: These side effects clear up within a few days. If you have signs & symptoms such as a sore throat & runny nose, try to stay hydrated and get plenty of rest. After consulting your doctor, you can also take over-the-counter medications to relieve such symptoms. 

Mild side effects of Emgality Auto-injector: Emgality can cause certain mild side effects, which usually do not require medical attention and are not serious. They usually disappear in a few days, but talk to your doctor if they become serious or worrying. This list does not include all possible side effects of Emgait, and there may be others, too. Report any new or bothersome symptoms to your doctor immediately. Mild side effects of Emgality include: 

• Constipation: While this is not a common side effect of Emgality, constipation can occur in some people using it. The exact mechanism why Emgality causes constipation is not entirely understood, but it is said to be related to its effects on the gastrointestinal system. 

• Vertigo: Some patients experience vertigo while using this medication. Until the vertigo subsides, avoid activities that require alertness. Tell your doctor if it is serious or persistent. 

• Nausea: Emgality can cause nausea and a general feeling of discomfort in the stomach in some people using it. This is said to happen because of the medication’s effect on the gastrointestinal system. You should remain properly hydrated if you experience persistent or severe nausea. 

• Fatigue: While this is an uncommon side effect of Emgality, some people experience it while receiving treatment with this medication. If you experience persistent weakness or if fatigue is negatively affecting your daily tasks, you should talk to an expert medical professional about ways to manage fatigue & improve your energy levels. 

• Pain in the joints and back: While the exact mechanism behind why this happens is not entirely understood, you should tell your doctor if you have joint or back pain while using Emgality Auto-injector. Usually, this tends to be mild to moderate in severity, but if it becomes serious, you should seek medical assistance. 

Adverse side effects of Emgality Auto-injector: Emgality can cause severe side effects in some people using it in some rare cases. These adverse side effects require immediate medical attention and may become life-threatening if left untreated. You should immediately seek medical assistance by calling your medical provider or 911 if you experience any of the following side effects. Not everyone using Emgality will experience these severe side effects. Serious side effects of Emgality include: 

• • Severe allergic reactions: Emgality Auto-injector may cause severe allergic reactions, such as anaphylaxis, which can become serious. Allergic reactions can occur days after starting treatment with the medication and might last a long time. You should discontinue using Emgality and immediately seek medical attention if you have signs and symptoms such as breathing problems, racing heart, fever, general feeling of illness, trouble swallowing, nausea, vomiting, and dizziness. 

• Cardiovascular events in patients with a history of heart disease: Patients with a history of heart disease using Emgality may experience increased risks of cardiovascular conditions such as strokes & heart attacks. This medication should be used with caution in such patients, and your healthcare provider will monitor you closely while you receive treatment with this medication to check your heart health. 

[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Emgality Auto-injector? 

Like other medications, Emgality also has certain warnings that you should consider while starting treatment to prevent migraines & treat cluster headaches. Key points of the warning include: 

• Your doctor, nurse, or healthcare provider will show you how to prepare and inject Emgality Auto-injector using a prefilled syringe. You should not inject yourself or someone else until you have been shown how to inject it. Consult your doctor, physician, or healthcare provider if you have any questions or concerns. 
• Emgality Auto-injector is for one-time use only. You should not share or reuse your prefilled syringe even if it has medication left in it. 
• Your doctor or healthcare provider may help you decide when and where to inject Emgality Auto-injector. 
• Do not use the Emgality Auto-injector without help from a caregiver if you have vision problems. 
• Caution is advised when using Emgality Auto-injector in patients with severe kidney or liver problems.

What Are the Emgality Auto-injector Precautions?

There are certain precautions that you should keep in mind before using Emgality. Before using this medication, share your complete medical history with your doctor or healthcare provider and tell them about all medications you are currently using or plan to use alongside the Emgaity Auto-injector. 

• Before using this medication, let your doctor or healthcare provider know if you are allergic to it or if any other ingredients are present in the medication. Also, tell them if you have any other allergies. Emgality Auto-injector may contain inactive ingredients that can cause hypersensitivity reactions or other problems. Ask your physician, pharmacist, or healthcare provider for the full list of medications. 
• If you plan to have surgery, including a dental procedure, tell your doctor, surgeon, or dentist about all your medications, including the Emgality Auto-injector. Also, tell them about all the prescription, non-prescription, and over-the-counter drugs & herbal supplements you are taking or planning to take. 
• This medication should only be needed during pregnancy when it is clearly needed. Before starting to take this medication while pregnant, you should discuss all potential risks & benefits with your doctor. 
• It is not known if galcanezumab passes into your breastmilk. Consult your doctor before breastfeeding a baby while you are taking this medication. 
• Do not share Emgality Auto-injector with other people, even if they have the same condition as you, as it can cause them harm. 

What Are the Contraindications of Emgality Auto-injector? 

Emgality Auto-injector is contraindicated for use in patients who have:

• Hypersensitivity
• Pregnancy
• Breastfeeding
• Individuals less than 18 years of age 
• Severe cardiovascular disease
• Latex allergy
• Severe renal or hepatic impairment

What If You Miss a Dose of Emgality Auto-injector?

• If you have missed a scheduled monthly dose of Emgality Auto-injector, you should take it as soon as you remember. 
• However, if it is almost time to take your next dose, you may omit the missed dose and continue taking your medication according to your regular monthly dosing schedule.
• Do not take double or extra doses to compensate for the missed dose. 
• You may set a reminder on your phone to prevent missing your medication dosage. 

[Note: If you have missed a medication dose and are still determining when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Emgality Auto-injector?

If you suspect an overdose of Emgality Auto-injector, you should immediately seek medical assistance. If someone has severe symptoms such as trouble breathing, seizures, and passing out, you should call 911 or the poison control helpline. You can also head to the nearest emergency room. 

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How to Store Emgality Auto-injector?

Proper storage of the Emgality auto-injector is crucial to ensure its effectiveness and safety. You can keep it in the refrigerator or at room temperature. Do not expose it to high temperatures or moisture, as it can affect how it may work. Follow the storage instructions below: 

• Refrigerate Emgality Auto-injector at 36°F-46°F or two °C to 8°C. 
• Do not allow the medication to freeze. Do not use it if frozen. Discard it safely. 
• Emgality Auto-injector can be stored at room temperature up to 86°F or 30°C for up to seven days. Discard it if it is not used within seven days at room temperature. 
• Keep the Emgality Auto-injector in its original container to protect it from direct sunlight. 
• Store it away from direct light, moisture, and excess heat. 
• Do not shake Emgality Auto-injector. 
• Remove the Emgality Auto-injector from the refrigerator thirty minutes before injection to allow it to reach room temperature. Do not use any heat source, such as a microwave or hot water, to warm it.
• Do not use this medication if its expiration date has passed, even if it is refrigerated. 
• Before using the Emgality Auto-injector, check for any change in visual appearance. Do not use it if the solution is cloudy, discolored, or contains particles. 
• Emgality auto-injectors are for single use only. Discard them after one use, even if medication is left in them. 
• Dispose of used auto-injectors in an FDA-approved sharps disposal container. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

Does Emgality Have Any Drug Interactions?

Like other medicines, Emgality Auto-injector may also interact with certain medications, which can reduce its effectiveness or cause unwanted side effects. To prevent Emgality interactions, you should tell your doctor about all the medications you currently use or plan to use alongside this medication, including all prescription and non-prescription medicines, over-the-counter drugs, herbs & vitamin supplements. This information helps you and your medical giver identify & manage potential drug interactions. Some of them include: 

• Other CGRP antagonists
• Erenumab
• Fremanezumab
• Eptinezumab 
• Triptans such as sumatriptan, rizatriptan, zolmitriptan
• Ergotamines such as ergotamine, dihydroergotamine
• NSAIDs such as ibuprofen, naproxen, aspirin
• Antidepressants
• SSRIs, SNRIs, TCAs
• Anticonvulsants
• Beta-blockers
• Botulinum toxin
• Oral contraceptives
• Vaccines
• Monoclonal antibodies
• CYP450 substrates

[Note: This isn’t a complete list, and there could be other drugs that interact with Emgality Auto-injector. Tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Other Emgality Auto-injector Interactions?

Apart from medicines, certain herbs, supplements, food items, and beverages may interact with Emgality Auto-injector and affect how it may work. While there are no known interactions between this medication and alcohol, you should not consume it in large amounts, as alcohol can trigger migraine attacks in some patients. You may also avoid beverages and medications containing alcohol. Talk to your doctor for more information and personalized medical guidance. Your doctor may suggest you make certain dietary and lifestyle while using this medication. 

What Is the Alternative to Emgality Injections?

While the Emgality Auto-injector is usually well tolerated, it may not be suitable for everyone and may fail to provide the desired results for some people. Due to this reason, patients look for alternatives to Emgality for migraine prevention and treatment of cluster headaches. If you plan to change your medication or start treatment with a new one, you should talk to your doctor. Based on your needs, condition, and other factors, they will help you determine the medication that is most suitable for you. Some of the most popular Emgality Auto-injector alternatives include: 

• Aimovig (erenumab)
• Ajovy (fremanezumab)
• Vyepti (eptinezumab)
• Qulipta (atogepant)
• Nurtec ODT (rimegepant)
• Topiramate (topiramate)
• Propranolol (propranolol hydrochloride)
• Amitriptyline (amitriptyline)
• Botox (onabotulinumtoxin A)
• Verapamil (verapamil)
• Valproic acid (valproic acid)
• Metoprolol (metoprolol)
• Candesartan (candesartan)
• Gabapentin (gabapentin)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Emgality Auto-injector Cost & Coupons

Multiple factors, including health insurance coverage and the pharmacy you use, can influence the cost of obtaining an Emgality Auto-injector at a low price. Emgality (galcanezumab) is primarily approved for the prevention of migraine headaches and the treatment of episodic cluster headaches. However, many Americans find that insurance coverage for medications like Emgality can be limited, especially for off-label uses, leading to significant out-of-pocket expenses. To manage this financial burden, many people turn to online platforms such as Polar Bear Meds to order Emgality prefilled syringe online from Canada in the USA and have them delivered to their doorstep conveniently. Additionally, first-time buyers can use the Emgality Auto-injector coupon code WELCOMEPB10 to get 10% off on their first order.

Frequently Asked Questions

Why is Emgality so painful? 

The thickness of the needle used for administering the medication dose can contribute to the pain at the injection site. This is usually described as a burning sensation and can be accompanied by inflammation, redness, or itching in the skin area where the injection was used. You can use prefilled pens, where you can inject the medicine without seeing the needle. This can lead to less than prefilled syringes. 

What should I do if I experience severe side effects from the Emgality Auto-injector?

If you experience severe side effects such as anaphylaxis, hypersensitivity reactions, or cardiovascular events, seek immediate medical attention. Call your doctor, pharmacist, or healthcare provider to discuss your symptoms and receive appropriate care. Always inform your doctor about any side effects you experience, especially if they are adverse or persistent.

How does the Emgality Auto-injector compare to other migraine treatments?

Emgality (galcanezumab) is a monoclonal antibody specifically targeting CGRP, a molecule involved in migraine attacks. It differs from other treatments such as triptans, ergotamines, and NSAIDs by focusing on prevention rather than acute symptom relief. Studies have shown that Emgality can significantly reduce the occurrence of migraine days compared to placebo. Discuss with your doctor how Emgality fits into your overall treatment plan and how it compares to other available options.

Can I use the Emgality Auto-injector if I have pre-existing health conditions?

Before using Emgality, inform your healthcare provider about any pre-existing health conditions, particularly severe cardiovascular disease, renal impairment, or hepatic impairment. Emgality may not be suitable for individuals with these conditions, and your doctor will need to evaluate the risks and benefits. Also, inform your physician or healthcare provider of any other prescription, non-prescription, or over-the-counter medications or supplements to avoid potential interactions.

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