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Exemestane

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Product Details

Description

Description

Exemestane is a steroidal aromatase inhibitor used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It works by irreversibly binding and inactivating the aromatase enzyme, resulting in a significant decrease in estrogen levels. Since certain breast cancer cells depend on estrogen to grow, this reduction helps slow tumor progression and makes Exemestane a vital component of postmenopausal hormone therapy. Its role in long-term care has made it an essential part of many treatment plans.

Typically, you can take one 25 mg tablet daily after a meal to enhance absorption and maintain consistent blood levels. If you're looking to start or continue treatment conveniently, you can buy Exemestane online from a trusted pharmacy without hassle. Always follow your doctor’s prescribed dosage and schedule to ensure the best possible results. The side effects, like hot flashes, fatigue, nausea, headache, and joint pain, are common.

To avoid complications, discuss any existing medications, allergies, or health conditions with your doctor before starting medication. If you miss the dose of Exemestane, take it when you remember, unless it’s close to your next one, then resume your regular schedule. If an overdose occurs, get emergency medical attention right away. Store Exemestane tablets in a dry, cool place, away from direct sunlight, and always keep them out of the reach of children for safety.

Uses and Benefits

Uses and Benefits

Exemestane is primarily used in postmenopausal women to manage breast cancer that is sensitive to estrogen. It is mainly prescribed for:

  • Recurring or persistent breast lumps
  • Pain or tenderness in the breast
  • Changes in breast shape or size
  • Inverted nipple or nipple discharge (especially clear or bloody)
  • Swelling in the breast or underarm area
  • Breast cancer recurrence symptoms, such as bone pain, fatigue, or unexplained weight loss, particularly if the cancer has spread (metastasized)

Benefits of Exemestane

  • Helps reduce estrogen levels by inhibiting the aromatase enzyme.
  • Slows or stops the growth of hormone receptor-positive breast cancer.
  • Lowers the risk of breast cancer recurrence after initial treatment.
  • Offers an alternative for patients who no longer respond well to tamoxifen.
  • Delays disease progression in advanced or metastatic breast cancer.
  • Taken as a once-daily oral tablet, it is convenient for long-term use.
  • Targets cancer cells more selectively compared to traditional chemotherapy.
Dosage

Dosage

What Are the Forms & Strengths of Exemestane?

Exemestane is available in the following form and strength:

  • Form: Oral tablet
  • Strength: 25 mg

What Is the Recommended Dosage for Exemestane?

If you are planning to buy Exemestane tablets for women, it is important to consult your doctor to determine the appropriate dosage for your situation. Below is the typical recommended dose for reference:

  • Postmenopausal women (early-stage hormone receptor-positive breast cancer): The recommended dose is 25 mg once daily, usually after 2–3 years of tamoxifen therapy.
  • Advanced or metastatic breast cancer: The dosage recommendation is 25 mg once daily, continued until disease progression is evident.

Note: Remember, the recommended dosage of Exemestane can vary individually. Discuss it with a doctor or healthcare expert, and they'll customize your dosage of Exemestane accordingly.

Usage Guide

Usage Guide

For optimal results and your safety, it’s crucial to adhere to the prescribed instructions when taking Exemestane. Below is a detailed usage guide covering all the important directions:

  • Take Exemestane as prescribed by the doctor. Do not change the dose or stop taking it without consulting your doctor.
  • The medication is usually taken once daily, preferably after a meal.
  • Swallow the tablet without breaking, chewing, or crushing it, accompanied by a glass of water.
  • Consistency is important—try to take Exemestane at the same time each day to maintain an even level of the medicine in your body.
  • Follow your doctor’s advice about the continuation of treatment, even if you start feeling better.

Note: Your doctor would determine the appropriate dosage of Exemestane for you based on your medical condition, following guidelines & studies on the drug. They'll adjust the dosage as needed.

How It Works

How It Works

Exemestane works by blocking a natural enzyme in the body called aromatase, which helps produce estrogen. In postmenopausal women, some types of breast cancer rely on estrogen to grow and spread. By lowering estrogen levels, Exemestane helps slow down or even stop the growth of these cancer cells. This targeted approach makes it an important part of hormone therapy, giving patients a better chance at managing their condition and preventing the cancer from coming back.

Side Effects

Side Effects

Common Side Effects of Exemestane: These side effects are generally mild; if they become bothersome, discuss them with your healthcare provider. Consider the following side effects:

  • Headache: You might notice a mild to moderate headache as your body adjusts to the hormonal changes brought on by the treatment. These headaches are usually short-lived and tend to improve over time as your system gets used to the medication.
  • Joint Discomfort: It’s not uncommon to feel some stiffness or aching in your joints. This happens because estrogen plays a role in joint health, and lower levels can sometimes lead to soreness.
  • Fatigue: Feeling tired or low on energy is fairly common, particularly during the early stages of treatment. Be kind to yourself—listen to your body and give it the rest it needs while it adapts.
  • Nausea: Some people feel a bit queasy, especially in the beginning. Taking your dose with a meal can often ease this feeling and make it more manageable.

Serious Side Effects of Exemestane: Although rare, Exemestane can cause you the following severe side effects:

  • Breathing problems or wheezing: Difficulty breathing or noisy breathing that requires urgent medical attention.
  • Racing heart: Rapid or irregular heartbeat that can feel unsettling or dangerous.
  • Fever or general ill feeling: Signs of possible infection or a serious reaction to the medication.
  • Swollen lymph nodes: Enlarged glands that could indicate an immune response or infection.
  • Trouble swallowing or throat tightness: Difficulty swallowing or feeling that the throat is closing, which can be life-threatening.
  • Itching, skin rash, or pale red bumps on the skin called hives: Allergic skin reactions that may worsen without treatment.

Note: Remember, this list might not cover all possible side effects of Exemestane. Always consult your healthcare expert or doctor for medical advice about its side effects.

Warnings

Warnings

While Exemestane is considered a safe drug, it carries certain warnings associated with its use. Understanding them lowers the risk of unwanted side effects. So, before you buy Exemestane for women, be mindful of the following warnings:

  • Not for use in premenopausal women: Exemestane is specifically designed for postmenopausal women and should not be used by women who are still menstruating or pregnant, as it may cause serious harm to a developing fetus.
  • Liver health monitoring: Since Exemestane is processed through the liver, patients with liver problems should use this medication cautiously and under strict medical supervision to avoid further liver damage.
  • Bone health concerns: The long-term use of Exemestane can either increase or decrease the risk of osteoporosis and fractures. Regular bone density monitoring and appropriate supplements like calcium and vitamin D may be recommended.
  • Allergic reactions: If symptoms like rash, swelling, severe dizziness, or difficulty breathing occur, seek emergency medical help immediately, as these may indicate a serious allergic reaction.
  • Regular medical check-ups: Frequent blood tests and follow-ups are important during treatment to monitor your response to the medication and catch any potential side effects early.
Safety Guide

Safety Guide

If you plan to buy Exemestane online from Canada, it’s crucial to become aware of safety precautions to ensure effective and safe use. Always follow your doctor’s advice carefully to minimize any risks. Here are some key safety instructions for Exemestane:

  • Liver Health: Patients with liver problems should have their liver function monitored regularly during treatment. Impaired liver function may affect how the drug is processed, increasing the risk of side effects.
  • Bone Health: Since Exemestane can reduce estrogen levels, it may lead to decreased bone density over time. Inform your doctor if you have a history of osteoporosis or bone fractures so they can monitor your bone health.
  • Allergy Risk: Inform your healthcare provider if you have any known allergies to Exemestane or similar medications. Allergic reactions, although rare, can be serious and require immediate medical attention.
  • Cardiovascular Concerns: If you have a history of heart disease or high cholesterol, discuss this with your doctor, as Exemestane may affect cholesterol levels and heart health.
  • Pregnancy and Breastfeeding: Exemestane is not recommended for use during pregnancy or breastfeeding. Always inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Driving and Operating Machinery: Some users may experience dizziness or fatigue while taking Exemestane.
  • Medical History Disclosure: Always share your complete medical history with your healthcare provider before starting Exemestane to ensure the medication is safe for your specific health conditions.
Missed Dose

Missed Dose

If you miss a dose of Exemestane, take it as soon as you recall, except if the next scheduled dosage is close. You can simply skip your missed dose & take the next scheduled dose. Avoid two doses at once to prevent possible side effects.

Note: If you miss a dose of Exemestane medication and are unsure when to take the next one, immediately consult your doctor or healthcare provider.

Overdose

Overdose

Taking more Exemestane than prescribed can be dangerous and may increase the risk of serious side effects. If you think you’ve taken too much of the medication, get emergency medical assistance right away. Signs of an overdose may include intense nausea, vomiting, extreme dizziness, or unexpected fatigue. Always keep your medication out of reach of others and follow the prescribed dosage carefully to avoid accidental overdose.

Note: If in case you have consumed more than the recommended dose of Exemestane, get medical help as soon as possible or call the Poison Help line at 1-800-222-1222.

Storage Guide

Storage Guide

  • Store Exemestane tablets at room temperature (20°C to 25°C or 68°F to 77°F).
  • Tightly seal the medication in its original container.
  • Protect the drug from moisture, heat, and direct sunlight.
  • Avoid storing Exemestane in humid places such as bathrooms.
  • Proper storage helps maintain the medication’s effectiveness and safety.

Note: Always consult your healthcare provider or doctor about the correct way to dispose of any unused Exemestane tablets and ask any questions you have about its proper storage to ensure safety and effectiveness.

Interactions

Interactions

Concurrent use of Exemestane with other medicines can impact how the drugs work in your body, potentially causing unwanted side effects or reducing effectiveness. If you plan to buy Exemestane for women, it’s important to inform your doctor about all medications you are taking. Below is a list of medicines and vaccines that may interact with Exemestane and require medical supervision:

Medicines and Vaccines Not Recommended with Exemestane:

  • Bacillus Calmette-Guérin (BCG) Vaccine, Live
  • Dengue Tetravalent Vaccine, Live
  • Measles Virus Vaccine, Live
  • Mumps Virus Vaccine, Live
  • Smallpox/Monkeypox Vaccine
  • Typhoid Vaccine
  • Varicella Virus Vaccine
  • Yellow Fever Vaccine

Medicines and Vaccines Usually Not Recommended but Sometimes Used with Caution:

  • Adenovirus Vaccine Type 4, Live
  • Adenovirus Vaccine Type 7, Live
  • Carbamazepine
  • Ceftobiprole Medocaril
  • Cholera Vaccine
  • Darolutamide
  • Ebola Zaire Vaccine, Live
  • Elexacaftor
  • Eltrombopag
  • Enzalutamide
  • Fosphenytoin
  • Influenza Virus Vaccine, Live
  • Mitotane
  • Phenytoin
  • Primidone
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Rotavirus Vaccine, Live
  • St John’s Wort
  • Voclosporin

What Are the Other Exemestane Interactions?

  • Food Interactions: Exemestane is best absorbed when taken after a meal. An empty stomach can reduce the effectiveness.
  • Alcohol Consumption: Drinking alcohol while on Exemestane may increase the risk of side effects like dizziness or liver stress. Avoiding or limiting alcohol is best during the treatment.
  • Herbal Supplements: These supplements may reduce Exemestane's effectiveness by speeding up drug metabolism in the liver. Always consult your doctor before taking herbal products.
  • Smoking: Smoking can affect hormone levels and may reduce the efficacy of Exemestane. If you're a smoker, let your doctor know to evaluate the best course of treatment.
  • CYP3A4 Enzyme Interactions: Exemestane is broken down in the liver by the CYP3A4 enzyme. Drugs that strongly affect this enzyme, such as rifampin, phenytoin, or carbamazepine, may alter how Exemestane works in your body.
  • Hormone Replacement Therapy (HRT): Using HRT with Exemestane is generally discouraged, as it can counteract the drug’s effect by adding estrogen to the system.
  • Other Estrogen-Containing Products: Avoid using products like estrogen creams, patches, or birth control pills while on Exemestane. They may interfere with its cancer-fighting benefits.

Note: This is not a complete list, and there could also be other drugs that interact with Exemestane. Be sure to inform your doctor about any prescription, OTC medications, and herbal products you’re taking.

Alternatives

Alternatives

Suppose Exemestane is not suitable or effective for you. In that case, your doctor may recommend alternative aromatase inhibitors or hormone therapies based on your medical condition, response to treatment, and any side effects. Common alternatives include:

  • Anastrozole (Arimidex): A widely used aromatase inhibitor that works similarly to Exemestane by lowering estrogen levels in postmenopausal women. It’s often prescribed for early-stage hormone receptor-positive breast cancer.
  • Letrozole (Femara): Another aromatase inhibitor that is effective in treating hormone-sensitive breast cancer. It may be used in both early and advanced stages of cancer in postmenopausal women.
  • Tamoxifen: This selective estrogen receptor modulator (SERM) is used as an alternative to aromatase inhibitors. It’s often prescribed for premenopausal women or for those who can’t tolerate Exemestane.
  • Fulvestrant (Faslodex): An estrogen receptor antagonist used to treat advanced breast cancer, especially when the cancer has progressed after other hormone therapies.
  • Megestrol Acetate: A synthetic progestin is sometimes used for advanced breast cancer when other hormone therapies are no longer effective.

Note: Only your doctor can decide the best alternative to Exemestane based on your condition. Never take substitute medications without medical advice, as it may lead to harmful side effects.

Cost & Coupons

Cost & Coupons

The cost of Exemestane can vary significantly depending on the pharmacy and your location. In the United States, many patients find it challenging to afford long-term hormonal treatments due to high retail prices. At Polar Bear Meds, we aim to ease this burden by offering Exemestane at competitive prices without compromising on quality. To make your first purchase even more affordable, use the coupon code “WELCOMEPB10” at checkout and receive 10% off. Our platform ensures safe, budget-friendly access to Exemestane for those who need it most.

FAQ

FAQ

Guarantee

Guarantee

AtPolarBearMeds.com, we assure you of the most affordable price of Exemestane online. You can buy Exemestane online from Canada through our trusted and licensed Canadian pharmacy. We ensure that every order is filled with high-quality, authentic medication that meets strict safety standards. With fast, direct shipping from Canada to your doorstep, you’ll receive your treatment quickly and securely. To place an affordable order or speak to a representative, call us1-888-779-2193toll-free at.

Important Notice

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by Dr. Jackson Miller (M.D)

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn

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