Ezetimibe

Ezetrol Tablet

Ezetrol 10 mg tablet is an FDA-approved medication used to treat high cholesterol. It contains ezetimibe as its active ingredient, which reduces bad cholesterol levels in the blood. For optimal effects, Ezetrol (10 mg) should be taken once daily with a glass of water, ideally at the same time every day. Children under ten years old are not advised to use this medication. Still, it is appropriate for adults and adolescents over that age. You can consult your physician or healthcare provider for personalized advice and guidance regarding storage, missed doses, overdose, and more, and follow their instructions for safe and efficient use. To ensure your medication is safe, buy Ezetrol online from trusted and reliable sources. 

Product Overview

Ezetrol 10mg Tablet contains the active ingredient ezetimibe, which treats high cholesterol by lowering “bad” cholesterol (LDL) levels in the blood. Ezetimibe works by decreasing the body’s ability to absorb cholesterol from the digestive system, specifically in the small intestine, which helps reduce overall cholesterol levels in the bloodstream. Ezetrol comes in a strength of 10 mg and should be taken once daily with a glass of water, preferably at the same time each day, for best results.

It can be taken with or without food. This medication is suitable for adults and adolescents over ten years of age. Still, it is not recommended for children under 10. Ezetrol can be used alone or in combination with statins to enhance its cholesterol-lowering effects. Common side effects of Ezetrol include joint pain, diarrhea, and muscle spasms. You must inform your doctor of all other medications before starting Ezetrol.

Pregnant and breastfeeding women should consult their healthcare provider before use. If a dose is missed, take it as soon as remembered unless it is close to the next dose; do not double doses. In case of overdose, seek immediate medical attention.

Store Ezetrol in its original container at room temperature below 30°C, away from direct sunlight, heat, and moisture. Keep it out of reach of children and pets. Consult your pharmacist or local waste disposal company to dispose of expired or unused medication properly.

Uses of Ezetrol

It is used for:

• Reducing cholesterol
• Adults and adolescents whose cholesterol levels are excessively high and cannot be sufficiently lowered by diet alone.
• Increasing HDL (good) cholesterol while lowering elevated triglycerides, total cholesterol, and LDL (bad) cholesterol.

How to Use Ezetrol?

Dosage

Ezetrol comes in the form of a capsule-shaped tablet that has a strength of:

• 10 mg

Recommended Dosage for Different Patients

For Coronary Heart Disease and ACS Event History

You may take Ezetrol 10 mg with a statin with proven cardiovascular benefits.

For the Elderly Patients

No change in dosage is necessary.

For Pediatric Patients≥ 10 years

No change in dosage is necessary.

For Pediatric Patients < 10 years

No clinical data support the medication’s safety and efficacy; therefore, treatment with ezetrol is not recommended.

For Hepatic Impairment

No change in dosage is necessary in patients with mild hepatic insufficiency. Ezetrol is not recommended for use in patients with moderate or severe liver dysfunction. 

For Renal Impairment

No change in dosage is necessary for renally impaired patients.

Co-administration with bile acid sequestrants

[Note: These recommendations may vary from person to person. Discuss them with your doctor; they’ll customize your dosage accordingly.]

How to Take It?

• For safe and efficient use, you should take the medication as directed by your doctor. 
• If you have any questions or concerns about the medication’s usage, consult your doctor or healthcare provider. 
• Ezetrol can be taken alone, in addition to diet, or in combination with other statins, which are medications that lower cholesterol.
• It is not recommended to consume large amounts of alcohol while receiving treatment with Ezetrol. You should also avoid taking medications and beverages that may contain alcohol. 
• Ezetrol should be used with caution in patients with liver disease. Such patients may require a dosage adjustment. 
• The usual daily recommended dosage of Ezetrol is for adults and pediatric patients ten years or older. The medication may be taken with or without food at any time convenient to you.
• Do not crush, chew, or break the tablet. Swallow the medication whole. 
• To help you remember, you should take the medication around the same time every day. 
• The dosage of your medication is based on the person’s body weight, medical conditions, and other medications you may be taking. 
• If your doctor has prescribed a different dose, do not change the dosage without consulting your doctor. 
• If you are planning to have surgery, including a dental procedure, tell your doctor about all the medications you are using, including Ezetrol. Also, tell them about the prescription medications, over-the-counter drugs, and herbal supplements you may be taking. 
• Ezetrol aids in lowering cholesterol. It doesn’t make your illness better. Therefore, if you want to reduce your cholesterol and keep it there, you need to keep taking it at the dose prescribed by your doctor.
• Continue taking this medication even if you feel well. Do not stop taking the medication abruptly. 
• Do not share Ezetrol with others, even if they have the same symptoms as you. 
• Tell your doctor or physician if your condition does not improve or if it worsens.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Ezetrol Work?

Ezetrol belongs to the cholesterol absorption inhibitor drug class. By reducing the body’s ability to absorb cholesterol from the digestive system, it lowers cholesterol levels.  It acts specifically in the small intestine, where it inhibits the absorption of dietary cholesterol. It aids in lowering blood cholesterol levels overall by lowering the quantity of absorbed cholesterol. When used together with statins, Ezetrol adds to the cholesterol-lowering effect of statins. This combination therapy is often prescribed for people with high cholesterol who need additional management beyond lifestyle changes (such as exercise and a healthy diet) alone. 

Important Safety Information

Side Effects

Common side effects of Ezetrol may include: 

• Diarrhea
• Joint pain
• Muscle spasms
• Nausea
• Neck pain
• Back pain
• Pain in arms and legs
• Indigestion 
• Heartburn 
• Dry mouth
• Abdominal pain
• Constipation
• Gallstones
• Hot flush
• High blood pressure

Mild side effects of Ezetrol may include: 

• Pain in extremity
• Sinus inflammation
• Upper respiratory tract infection
• Elevations in some laboratory tests of liver and muscle function
• Wind or excessive gas in the stomach or bowel
• Inflammation of the gallbladder
• Swelling, especially in the hands and feet

Adverse side effects of Ezetrol may include: 

• Bleeding or bruising more easily than normal
• Dark coloured urine
• Difficulty in swallowing or breathing
• Inflammation on the face, lips, mouth, throat or tongue
• Joint pain
• Light-colored bowel motions
• Severe allergic reaction 
• Skin rash and hives
• Steady abdominal pain with nausea and vomiting
• Unexplained muscle aches, tenderness, or weakness not caused by exercise.
• Yellowing of the skin and eyes

[Note: This list may not cover all possible side effects. Always consult with your healthcare provider for medical advice about side effects.]

Warnings

• You should not take Ezetrol if:
  • You have an allergy to ezetimibe or any other active or inactive ingredients in the medication. 
  • The packaging is torn, damaged, or tampered with
  • The expiration date on the label has passed. If you take a medication after the expiry date has crossed, it may not work. 
• You should not use Ezetrol along with a statin disease if you have:
  • Active liver disease
  • Breastfeeding or pregnancy
• You should not use Ezetrol if you have gallbladder disease.
• Before using this medication, share your complete medical history with your doctor, especially if you have the following conditions:
  • Liver disease
  • Allergy to any medicine, dyes, or preservatives
  • Take any other medicines for other conditions.

Precautions

• In rare cases, people may have allergic reactions to Ezetrol, such as severe rash, itching, swollen face, or difficulty breathing. If you experience any of these symptoms, contact your doctor immediately.
• Ezetrol may be used alone or with statins (e.g., atorvastatin, pravastatin) to lower cholesterol. If used together, liver function should be carefully monitored. This combination is not recommended for pregnant women or those with active liver disease or elevations in some laboratory tests of liver function. 
• Liver disease or reduced liver function may cause this medication to accumulate in the body, leading to unwanted side effects. Discuss with your doctor how it affects your condition and whether special monitoring is needed. Regular liver function tests may be required.
• Ezetrol can cause muscle pain or damage. Contact your doctor if you experience unexpected muscle pain, weakness, or tenderness, especially if it persists.
• Ezetrol may cause inflammation of the pancreas. Those with a history or risk of pancreatitis should be closely monitored. Symptoms may include upper left abdominal pain, back pain, chills, fever, nausea, rapid heartbeat, and swollen abdomen. If these occur, seek medical attention immediately. 
• Ezetrol should only be used during pregnancy if the benefits outweigh the risks. Contact your doctor if you become pregnant while taking this medication.
• It is not known if this medication passes into breast milk. If you are breastfeeding, discuss with your doctor whether you should continue taking this medication.
• The safety and effectiveness of this medication have not been established for children under ten years old, and it is not recommended for use in this age group. 

Contraindications

Ezetrol is contraindicated for use in patients who have:

• Hypersensitivity to the medication or any of its active/ inactive ingredients. 
• Liver disease or unexplained persistent elevations in serum transaminase.

Missed Dose

• For the best results from the medication, it is crucial to maintain consistency in dosage and take it around the same time every day. 
• If you have missed a dose of Ezetrol 10 mg tablet, take it as soon as you remember. 
• However, if it is almost time for you to take the next dose of Ezetrol, you may omit the missed dose and continue as per your regular dosing schedule. 
• Do not take double or extra doses to compensate for the missed dosage. 
• Do not take two doses of the same medication simultaneously. 
• Try setting a reminder on your phone to avoid missing doses. 

[Note: If you have missed a medication dose and are still determining when to take the next one, consult your doctor or pharmacist immediately.]

Overdose

Do not take Ezetrol more frequently or in large quantities or longer than recommended, as it can lead to unwanted side effects. If someone has overdosed on the medication and is experiencing severe side effects such as difficulty breathing, seizures, and passing out, it is crucial to seek immediate medical help. You can call 911 or head to the nearest emergency room. Do this even if there are no bothersome signs and symptoms. 

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

Storage

• Keep the medication in its original container at a controlled room temperature away from direct sunlight, direct heat, and moisture. 
• Do not store Ezetrol or other medication in the bathroom or near a sink. You should also not leave it on the window sills or car as heat and moisture can cause harm to some drugs. 
• Keep all medicines, including Ezetrol, in a safe place away from the sight and reach of children and pets. 
• Do not keep medications that are outdated or no longer needed. 
• Discard such medications properly so children, pets, and others cannot consume them. 
• Do not throw unwanted medicines in your household garbage bin or pour them into the drain. 
• Do not flush the medicine in the toilet unless instructed otherwise. 
• Do not dispose of the medication in wastewater, as it can cause pollution. 
• The best way to eliminate unwanted medication is to give it away in a medicine-take-back program. 
• For more information on disposing of unwanted and expired medications, consult your pharmacist, healthcare provider, or local waste disposal company. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

Ezetrol Interactions

Ezetrol’s interaction with any of the following medications may affect its effectiveness. Consult your healthcare provider for more details on drug interactions.  

• cholestyramine
• colestipol
• colesevelam
• cyclosporine
• eltrombopag
• fibrates
• teriflunomide
• warfarin

[Note: This isn’t a complete list, and there could be other drugs that interact with Ezetrol. Tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

Ezetrol Alternatives

• Ezetimibe (ezetimibe)
• Crestor (rosuvastatin)
• Fluvastatin (fluvastatin sodium)
• Leqvio (inclisiran)
• Lipitor (atorvastatin)
• Livalo (pitavastatin)
• Lopid (gemfibrozil)
• Lovastatin
• Praluent (alirocumab)
• Pravastatin
• Questran (cholestyramine)
• Repatha (evolocumab)
• Tricor (fenofibrate)
• Welchol (colesevelam)
• Zocor (simvastatin)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Frequently Asked Questions

Can Ezetrol be taken alongside other cholesterol-lowering medications?

Yes, Ezetrol (ezetimibe) can be taken with statins and other cholesterol-lowering medications to enhance the overall cholesterol-lowering effect. This combination therapy is often used for patients who need additional management beyond lifestyle changes alone. Following your doctor’s instructions regarding dosage and combination therapy is important.

What should I do if I experience muscle pain while taking Ezetrol?

Muscle pain or weakness can be a side effect of Ezetrol. Contact your doctor immediately if you experience unexpected muscle pain, tenderness, or weakness, especially if it persists. This could indicate a severe condition known as rhabdomyolysis, particularly when Ezetrol is used in combination with statins.

How does Ezetrol affect liver function, and what monitoring is required?

Ezetrol may impact liver function, especially when used with statins. Patients with a history of liver disease or those taking Ezetrol in combination with other cholesterol-lowering medications should have their liver function monitored regularly. Your doctor will schedule routine blood tests to check liver enzyme levels and ensure safe use of the medication.

Are there dietary restrictions while taking Ezetrol?

While taking Ezetrol, it is advised to maintain a healthy diet low in saturated fats and cholesterol. Although Ezetrol helps lower cholesterol levels, dietary modifications are an essential part of the treatment plan. Avoiding high-fat foods can enhance the effectiveness of the medication and support overall cardiovascular health.

What should be done in case of an Ezetrol overdose?

In the event of an Ezetrol overdose, seek immediate medical attention. Symptoms of overdose may include severe dizziness, fainting, or difficulty breathing. Contact emergency services or go to the nearest emergency room. Do not wait for symptoms to appear; prompt medical intervention is crucial.

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