Levomilnacipran  

Fetzima

Fetzima is an FDA-approved antidepressant that is used to treat major depressive disorder in adult patients. It contains levomilnacipran, which inhibits the reuptake of serotonin and norepinephrine, increasing their availability in the central nervous system, which helps regulate mood and emotional well-being. The prescription medication is available as an extended-release capsule in strengths of 20 mg, 40 mg, 80 mg, and 120 mg, usually taken daily with or without food. Consult your healthcare provider or physician for personalized advice and guidance, and seek their help if you have any queries or concerns regarding the use of the medication. To ensure your medication is genuine, buy Fetzima (levomilnacipran) online from trusted and reliable sources. 

Product Overview

Fetzima generic name is the main ingredient, levomilnacipran, used to treat and manage major depressive disorder in adult patients. This antidepressant works by inhibiting serotonin and norepinephrine reuptake, increasing their availability in the central nervous system, which helps regulate mood and emotional well-being. Fetzima is available as an extended-release capsule in strengths of 20 mg, 40 mg, 80 mg, and 120 mg. It is typically taken once daily, starting at 20 mg for the first two days, then increased to 40 mg.

Your doctor may adjust the dosage, to a maximum of 120 mg daily. This medication should be swallowed whole, not chewed or crushed, and can be taken with or without food. It is intended for use by adults diagnosed with major depressive disorder. Common side effects of Fetzima include nausea, constipation, vomiting, excessive sweating, and erectile dysfunction. More severe side effects can consist of serotonin syndrome, high blood pressure, increased risk of bleeding, urinary difficulties, low sodium levels, seizures, and allergic reactions. 

Patients should be aware of the potential for increased suicidal thoughts, especially during the initial treatment period. Precautions include informing your doctor of any medical history, especially related to heart problems, glaucoma, or bipolar disorder. In case of a missed dose, take it as soon as remembered unless it is close to the next dose. Avoid doubling up doses. Store Fetzima in a cool, dry place away from children and pets. If an overdose occurs, seek immediate medical assistance.

What Is Fetzima Used to Treat?

• It is used to treat and manage MDD (major depressive disorder). 

What Are the Available Doses of Fetzima?

Fetzima extended-release capsule is available in the following strengths:

• Fetzima 20 mg capsule
• Fetzima 40 mg capsule
• Fetzima 80 mg capsule
• Fetzima 120 mg capsule

What Is the Typical Dosage for Fetzima?

Dosage of Fetzima for Major Depressive Disorder

• Start: Take 20 mg by mouth once daily for the first two days.
• Adjustment: After two days, the dose may be increased to 40 mg once daily.
• Maintenance: Your doctor can further increase your dose by 40 mg every two days, up to a maximum of 120 mg daily.
• Customisation Treatment: The duration can vary. Depending on your depression symptoms, you may need to continue taking Fetzima for several months or longer. 

Your doctor will regularly check your symptoms every few months to decide if you should continue the Fetzima for fibromyalgia.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How Do You Take Fetzima?

Before taking the Fetzima for fibromyalgia, you should carefully read and follow the instructions in the patient information leaflet included with your prescription. Here’s how to take your Fetzima capsules correctly:

• Discuss the potential risks and benefits with your doctor or healthcare provider prior to using this medicine.
• If you have any questions or concerns about how to use the medication, consult your physician or pharmacist. 
• You should use this medication exactly as your doctor directed. You must take it orally by mouth, with or without food. 
• Do not chew, crush, break, or open the Fetzima 120 mg capsule. Swallow it whole. 
• If you break the capsule, it can release all medication at once, which may increase your risk of unwanted side effects.
• The medication dosage is based on your medical condition, your body’s response to treatment, and other medications you may be taking. Tell your doctor, healthcare provider, or pharmacist about all your medications, including all prescription medications, over-the-counter and non-prescription drugs, and herbal supplements you may be taking. 
• Your doctor may direct you to start Fetzima at a low dosage and gradually increase your dose to reduce your risk of side effects. Follow all instructions given to you by your doctor carefully. 
• To get the most benefit of your medication, you should maintain consistency in dosage and take Fetzima around the same time daily.
• You can take this medication at any time of day that is convenient for you, but you should try to take it around the same time every day.
• Do not increase your dosage or use this dosage more frequently or for longer than prescribed. Taking your medication more often or in large quantities will not improve your condition any faster, but it will increase your risk of unwanted side effects. 
• You may start feeling improvements in your symptoms as soon as a couple of weeks after taking this medication. 
• It may take around six to eight weeks before you get the full benefit of this medication. 
• Continue taking this medication even if you feel well. 
• You should not abruptly stop taking this medication without consulting your doctor or healthcare provider. Certain conditions may worsen when you suddenly stop taking this medication. 
• Additionally, you may experience symptoms such as headache, fatigue, mood swings, sleep changes, and more when you are stopping treatment with this drug. To prevent this, your doctor will taper your dose gradually. 
• You should report any new or worsening symptoms to your doctor immediately. 
• Tell your doctor if your condition does not improve or worsens after six to eight weeks of treatment. Your doctor may suggest that you take other medication to treat your condition.  

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Fetzima Work?

Fetzima is an antidepressant approved for the treatment of major depressive disorder in adult patients. The precise mechanism of levomilnacipran’s antidepressant effect is not fully understood. Still, it is presumed to work by inhibiting the reuptake of serotonin and norepinephrine transporters in the central nervous system. Doing so enhances the availability of these neurotransmitters, which play crucial roles in mood regulation and emotional well-being.

What Are the Important Safety Information for Using Fetzima?

What Are the Side Effects of Fetzima?

Common Fetzima Side Effects: Fetzima for fibromyalgia is a medication that, like any other, can bring about some side effects. These effects are typically temporary and should last only a few days to a few weeks. If you notice that these effects aren’t going away, start to bother you more over time, or get worse, it’s important to discuss this with your doctor or pharmacist to keep you safe. Here’s what you might experience while taking Fetzima:

• Nausea: This is when you feel sick to your stomach, like you might throw up.
• Constipation: This happens when you have difficulty going to the bathroom or you’re not going to the bathroom as often as you normally do.
• Vomiting: This is when you throw up the contents of your stomach.
• Excessive sweating: You may find yourself sweating a lot more than usual, even if you’re not doing any physical activity or it isn’t particularly hot.
• Erectile dysfunction: This side effect involves trouble getting or keeping an erection, which can affect sexual activity.
• Decreased appetite: You might notice that you’re not as hungry as usual, which could lead to eating less than you typically would.
• Tachycardia: This means your heart is beating faster than what’s considered normal for you when you’re at rest.
• Palpitations: This is when it feels like your heart is racing or fluttering in your chest, which can be uncomfortable and alarming. 

Adverse/Serious Fetzima Side Effects: Fetzima, like any medication, can sometimes cause serious side effects that need immediate attention. If you experience any of the following effects, contact your doctor right away. If you think your situation is life-threatening, don’t hesitate to call 911 or your local emergency number. Here are the serious side effects associated with Fetzima:

• Serotonin Syndrome: This is a potentially life-threatening condition where there’s too much serotonin in your body. Symptoms can include confusion, hallucinations, a high fever, sweating, shaking, rapid heart rate, and seizures.
• High Blood Pressure or Rapid Heart Rate: Be alert for signs like chest pain, a severe headache, dizziness, or difficulty breathing.
• Higher Risk of Bleeding: You might notice unusual bleeding or bruising, black or pink stools, longer bleeding from cuts, or frequent nosebleeds. Your urine might also appear pink or red.
• Trouble Urinating: This includes difficulty starting urination, painful urination, or feeling like your bladder isn’t completely empty.
• Low Sodium Levels in Your Blood: Low sodium can be very serious, leading to confusion, headaches, weakness, problems with memory or concentration, fainting, or in severe cases, coma and seizures.
• Seizures: Watch for sudden confusion, uncontrollable jerking or muscle spasms, loss of consciousness, or rapid blinking.
• Sexual Dysfunction: This may involve difficulties with sexual performance or desire.
• Severe Allergic Reaction: Symptoms may include trouble swallowing, skin discoloration, fainting, itching, rashes, and swelling around your feet, ankles, toes, tongue, throat, or lips.
• Suicidal Thoughts and Behaviors: Changes in behavior like acting on dangerous impulses, aggression, restlessness, insomnia, irritability, panic attacks, or feeling unusually anxious could indicate a serious issue.

[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

What Are the Warnings for Using Fetzima?

When you choose to buy Fetzima from Canada, it’s crucial to carefully consider both the potential risks and benefits of the medication. Deciding to use Fetzima should be a joint decision made between you and your doctor. Before you start taking Fetzima for fibromyalgia, keep these points in mind:

• Before taking Fetzima for anxiety, you should consult your doctor regarding potential side effects and benefits and share your complete medical history with your doctor. This medication may not be right for you if you have certain medical conditions, such as:
  • Bipolar disorder
  • Breastfeeding
  • Difficulty urinating
  • Glaucoma
  • Heart problems 
  • Seizure 
  • Pregnancy 
• Fetzima 120 mg capsule may increase your blood pressure and heart rate. If you have hypertension or heart conduction disorder, this medication may make your condition worse. Consult your doctor about any heart-related or blood pressure-related problems before taking this medication. 
• If you have angle closure glaucoma, this medication may cause further problems with your vision. It may cause your pupil to dilate, triggering a serious reaction known as an angle closure attack. Its symptoms may include eye pressure, severe eye pain, blurred vision, nausea/vomiting, or halos around lights. Call your doctor right away if you experience such symptoms. 
• This medication may cause urinary hesitancy or difficulty urinating in some patients. If you experience trouble urinating, this medication may worsen your condition. If you have urinary problems, consult your doctor. 
• This medication may worsen your symptoms of bipolar disorder, which may lead to manic episodes. If you have bipolar disorder, talk with your doctor before taking this medication.
• This medication may reduce your seizure threshold, which can increase your risk of experiencing seizures. Let your doctor know if you have a history of bipolar disorder.
• It is unknown if this medication causes any harm to the fetus during pregnancy. Other medications that are similar to Fetzima have caused complications in pregnancy when taken during the third trimester. 
• It is not known if this medication is safe to take while breastfeeding a baby. Talk with your doctor to determine whether this medication is safe for use while nursing a baby. 

Does Fetzima Have a Black Box Warning?

Fetzima for fibromyalgia has a boxed warning regarding the increased risk of suicidal thoughts and behaviors, which may also worsen your depression. You are at increased risk during the first few weeks of treatment. If you have any thoughts of self-harm, call your doctor immediately and report your symptoms. Additionally, the FDA does not approve this medication for pediatric patients. In some studies, it was found that this medication may increase the risk of suicidal thoughts and behavior in children, adolescents, and individuals less than 24 years old. 

What Precautions Should Be Taken with Fetzima?

Before you buy Fetzima online or start taking it, make sure to talk about your medical history with a doctor. This medication might not be the right treatment for you if you have certain health conditions or other factors affecting your health. The conditions and factors to consider include:

• Before taking Fetzima for anxiety, let your doctor know if you are allergic to it or any of its ingredients or if you have any other allergies. 
• This medication may cause drowsiness or blurred vision. Consuming alcohol or cannabis may make you more dizzy. You should not consume large amounts of alcohol and avoid beverages and medications that may contain alcohol. 
• You should not drive, operate heavy machinery, or engage in activities that may require clear vision or alertness unless you have determined how this medication may affect you. 
• If you are planning to have surgery, including a dental procedure, let your doctor, surgeon, or dentist know about all the medications you are taking, including Fetzima. You should also tell them about all prescription, over-the-counter, and non-prescription drugs, and herbal supplements you may be taking.  
• Geriatric patients may be more sensitive to the side effects caused by this medication, especially bleeding. They may be at an increased risk of mineral imbalance while using this medication, especially if they are taking diuretics. 
• During pregnancy, this medication should only be taken when it is clearly needed, as it may cause harm to the unborn baby. Let your doctor know if you are pregnant, suspect a pregnancy, or if you are planning to become pregnant. 
• Since untreated mental/mood disorders can be a serious condition, you should not stop taking this medication unless directed by your doctor. If you think you may be pregnant, talk to your doctor and discuss with them the risks and benefits of using this medication in your condition. 

What Are the Contraindications for Fetzima?

Fetzima for fibromyalgia is contraindicated for use in patients who:

• Have a hypersensitivity to this medication or any of the ingredients present in the medication. 
• Use Fetzima in conjunction with monoamine oxidase inhibitors due to an increased risk of serotonin syndrome. When starting Fetzima therapy after stopping an MAOI, at least 14 days should pass. You should wait at least seven days after stopping Fetzima before beginning an MAOI.

What Happens If I Miss a Dose of Fetzima?

If you forgot to take your Fetzima for anxiety on time, here’s what you should do to avoid any complications:

• To get the best results from this medication, you should maintain consistency in dosage and take it at the same time every day. 
• If you miss a dose of the Fetzima 120 mg capsule, you should take it as soon as you remember. 
• However, if it is almost time for your next dose, you may omit the missed dose and continue taking the medication according to your regular dosing schedule. 
• You should not take two doses of the same medication simultaneously. 
• You should not take extra or double doses of Fetzima to compensate for the missed dosage. 
• To further avoid missing your dosage for Fetzima, you should try setting a reminder on your phone. 

[Note: If you have missed a medication dose and are still unsure when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Overdose on Fetzima?

You should not take Fetzima for fibromyalgia more than recommended or more frequently than prescribed, as it may cause unwanted side effects. If you experience side effects such as fainting, seizures, or loss of consciousness, seek immediate medical assistance. You can call 911 or head to the nearest emergency room. 

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How Do You Store Fetzima Capsules?

Below are some instructions you should follow while storing your Fetzima capsules so the medication stays effective and safe until its expiration date:

• Keep the medication cool and dry, away from direct sunlight, moisture, or excess heat. 
• Do not keep it in the bathroom, window sill, or inside the car. 
• Keep all medications, including Fetzima, in a safe place away from the sight and reach of children and pets. 
• Do not keep medications that are outdated or no longer needed. 
• Do not throw unwanted medications in the household garbage bin or pour them into the drain. 
• Do not flush it down the toilet or dispose of it in wastewater. 
• Discard the unwanted medications in a way that prevents children, animals, and others from consuming them. 
• The best way to eliminate unwanted medication is to give it away in the medicine take-back program.
• To learn more about properly disposing unwanted medications, consult your healthcare provider, pharmacist, and local waste disposal company. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

What Medications Should Not Be Taken with Fetzima?

Fetzima for anxiety can interact with a range of medications, which might impact how it works or increase the risk of side effects. Here’s an explanation of how interactions with some common types of medications could affect your treatment with Fetzima:

• Antidepressants (like Amitriptyline, Citalopram, Duloxetine): Taking Fetzima with other antidepressants can increase the risk of serotonin syndrome, a potentially life-threatening condition caused by too much serotonin in the brain.
• MAO Inhibitors (such as Isocarboxazid, Phenelzine, Selegiline): These drugs can also lead to serotonin syndrome when taken with Fetzima. Generally, there should be a 14-day gap between stopping MAO inhibitors and starting Fetzima to avoid this risk.
• Blood Thinners (like Apixaban): Fetzima might enhance the effects of these medications, potentially increasing the risk of bleeding.
• Pain Medications (such as Meperidine, Tramadol): These can interact with Fetzima to increase the risk of serotonin syndrome.
• CNS Stimulants (such as Dexmethylphenidate, Phentermine): These can raise heart rate and blood pressure, and taking them with Fetzima might enhance these effects.
• Anti-nausea Medications (like Ondansetron, Granisetron): When combined with Fetzima, these drugs can affect the electrical activity of the heart.
• Herbal Supplements (like St John’s Wort): These can reduce the effectiveness of Fetzima or increase side effects.

This is not an exhaustive list, but it highlights the need for careful management of drug interactions when taking Fetzima. Always discuss all your current medications with your healthcare provider to safely manage potential interactions.

[Note: There could be other drugs that interact with Fetzima. Tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Fetzima Alternatives?

There are various medications available to treat major depressive disorder (MDD), also known simply as depression. Depending on your specific needs and health profile, some drugs might be more suitable for you than others. If you’re considering alternatives to Fetzima, it’s a good idea to discuss this with your doctor. 

Some of the drugs mentioned here might be used in ways not originally approved by regulatory agencies, a practice known as “off-label” use. This means a medication approved for one condition is used to treat another. Here are some examples of drugs that can be used to treat MDD:

• Celexa (citalopram)
• Trintellix (vortioxetine)
• Savella (milnacipran)
• Lexapro (escitalopram)
• Prozac (fluoxetine)
• Paxil (paroxetine)
• Zoloft (sertraline)
• Viibryd (vilazodone)
• Cymbalta (duloxetine)
• Effexor XR (venlafaxine)
• Pristiq (desvenlafaxine)
• Wellbutrin XL (bupropion)
• Nardil (phenelzine)
• Parnate (tranylcypromine)

[Note: Your doctor will choose what’s best for you. Don’t use any of these Fetzima alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Fetzima Coupons & Cost

Fetzima, often prescribed for depression, can be expensive in the U.S., with costs that can significantly impact your budget if you’re uninsured. You can greatly reduce this financial strain by choosing to buy Fetzima online from Canada through Polar Bear Meds. We provide Fetzima at prices that are considerably lower than those typically found in U.S. pharmacies, offering a budget-friendly solution for American residents seeking effective mental health care. Make sure to use the Fetzima coupon code “WELCOMEPB10” to receive an additional 10% off your first purchase. Also, participate in our referral program to further decrease your expenses, potentially saving up to $200 on your medication.

Frequently Asked Questions

Should Fetzima be taken at night?

Fetzima for anxiety can be taken either in the morning or at night, depending on what fits best with your daily routine. However, it’s important to take it at the same time each day to maintain consistent levels of the medication in your body, which helps effectively manage your symptoms.

How long does Fetzima last?

The half-life of Fetzima, which is the time it takes for half of the drug to be eliminated from the body, is about 12 hours. It typically takes about 60 hours (or five half-lives) for Fetzima to be completely cleared from the body.

Do you need to wean off Fetzima?

Yes, you should not stop taking Fetzima abruptly. To avoid withdrawal symptoms, discuss with your doctor about gradually reducing your dose. This process, known as tapering, involves slowly decreasing the dosage of Fetzima over time until it is safe to stop completely.

How quickly does Fetzima work?

Fetzima begins to work after your first dose, but it might take a few weeks for you to notice an improvement in your depression symptoms. If you don’t see any change after 6 to 8 weeks, you should talk to your doctor about possibly adjusting your treatment.

What is the best time of day to take Fetzima?

You should take Fetzima once a day at about the same time each day. You can take it with or without food. Remember to swallow the capsules whole without opening, chewing, or crushing them.

Can you just stop taking Fetzima?

Stopping Fetzima suddenly is not advisable. If you’re thinking about stopping, you should first discuss it with your healthcare provider. Stopping abruptly can lead to withdrawal symptoms, which may be severe. Your doctor will likely suggest gradually reducing your dose to minimize these symptoms.

What are the benefits of Fetzima?

Fetzima is primarily used to treat major depressive disorder. It’s important to note that while a similar medication, milnacipran (Savella), is used for treating chronic pain disorder like fibromyalgia, Fetzima for anxiety is not approved for this use.

Can Fetzima be used in combination with other antidepressants?

Fetzima should generally not be combined with other antidepressants, especially monoamine oxidase inhibitors (MAOIs), because of the risk of developing serotonin syndrome, a potentially life-threatening condition. Always check with your healthcare provider before mixing Fetzima for anxiety with other medications to prevent any harmful interactions or side effects.

Is it safe to use Fetzima during pregnancy or while breastfeeding?

The safety of Fetzima for anxiety during pregnancy and breastfeeding is not well established. Similar medications have caused complications when used during the third trimester. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits with your healthcare provider to determine the best course of action.

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