Invokana

Invokana is a prescription medicine for adults with type 2 diabetes. This medication helps lower blood sugar by making the kidneys remove excess sugar from your blood and excrete it in your urine. It comes in 100 mg and 300 mg tablets and is taken once daily, usually before breakfast. For best results, it should be used along with a healthy diet and regular exercise. It may also help protect the kidneys and heart when taken as prescribed.

Invokana is an FDA-approved medication used to improve glycemic control in adults with:

• Type 2 diabetes

If you are prescribed to use Invokana for type 2 diabetes, follow these administration guidelines:

• Take Invokana once daily, usually before your first meal of the day (breakfast).
• Swallow the Invokana tablet whole with a glass of water.
• Try to take Invokana at the same time each day to help maintain your blood sugar levels.
• Continue your diet and exercise plan as advised by your doctor while taking Invokana.
• Your doctor may adjust the Invokana dose depending on your blood sugar levels and kidney function.

When you consider the Invokana dose for type 2 diabetes, follow this table:

Invokana works by helping your kidneys get rid of extra sugar from the blood through urine. Normally, the kidneys filter sugar and then reabsorb it back into the body, but Invokana blocks this reabsorption. As a result, more sugar leaves the body when you pass urine, which lowers blood sugar levels in people with type 2 diabetes.

If you have missed an Invokana dose, take it as soon as possible. If it’s already close to your next scheduled Invokana dose, skip the missed one. After that, you can continue with your daily Invokana dosing schedule. Do not take extra Invokana tablets to make up for the missed dose. You should try to take it at the same time each day to avoid missed Invokana doses.

Overdosing on Invokana tablets may lead to dangerous side effects. This includes fluid loss, a sharp drop in blood pressure, and life-threatening acid-base disturbances like diabetic ketoacidosis. DKA is an emergency that requires urgent hospital care. This may present with symptoms like continuous vomiting, intense thirst, nausea, stomach pain, mental confusion, and a fruity odor on the breath. If you suspect an Invokana overdose, contact the poison control center or your healthcare provider immediately.

This table highlights their drug classes and benefits, so you can quickly see how they differ.

No, Invokana (canagliflozin) does not need to be refrigerated. Refrigeration will not improve its effectiveness. Follow these Invokana storage guidelines if you want to store this medication:

• It should be stored at room temperature, ideally between 20°C-25°C (68°F-77°F).
• Invokana tablets should be kept away from moisture and heat.
• Keep these tablets in their original bottle with the lid tightly closed.
• This medication should be kept out of reach of children and pets.
• Avoid exposing these tablets to extreme temperatures.

• Do not use Invokana if you are allergic to:
  • Canagliflozin
  • Any medicine that contains canagliflozin
  • Any ingredient in the Invokana product you were given
• Do not use Invokana tablets if you have serious liver problems or if your liver is not working properly. Your healthcare provider may do liver tests before prescribing it.
• Adults aged 65 or older may be at higher risk of side effects.
• Invokana should not be used for diabetic ketoacidosis (DKA).
• Some patients may have a higher chance of bone fractures while taking Invokana.
• Invokana may increase potassium levels, particularly in patients with kidney problems. It is not recommended for patients with serious kidney disease or those on dialysis.
• Invokana may harm an unborn baby. Tell your doctor or healthcare expert if you are pregnant or planning to become pregnant while taking Invokana tablets.
• It is unknown if this medicine passes into breast milk. If you are breastfeeding or plan to breastfeed, consult your doctor for guidance on whether to continue the medication.
• Invokana should not be used for the treatment of type 1 diabetes.
• Stop using Invokana tablets at least 3 days before major surgery or prolonged fasting to reduce the risk of ketoacidosis.
• Patients are highly advised to maintain good genital hygiene. You need to keep the area clean and dry. This is because Invokana can increase the risk of genital mycotic infections.
• Avoid or use caution with ketogenic or very low-carbohydrate diets. They can increase the risk of euglycemic DKA while taking Invokana.

Invokana (canagliflozin) is associated with interactions involving 404 medications and 4 medical conditions. Among these drug interactions, 5 are considered major, 391 moderate, and 8 minor. Some of the Invokana interactions are listed below:

• Major Invokana Interactions
  • Capivasertib
  • Gatifloxacin
  • Lithium
  • Morphine
  • Pralsetinib
• Minor Invokana Interactions
  • Dexamethasone Ophthalmic
  • Difluprednate Ophthalmic
  • Fluocinolone Ophthalmic
  • Fluorometholone Ophthalmic
  • Loteprednol Ophthalmic
  • Medrysone Ophthalmic
  • Prednisolone Ophthalmic
  • Rimexolone Ophthalmic
• Moderate Invokana Interactions
  • Aliskiren
  • Levobunolol Ophthalmic
  • Amiloride
  • Acetohexamide
  • Nifedipine
  • Tamsulosin
  • Levothyroxine
  • Gemifloxacin
  • Bumetanide
  • Acetazolamide
  • Fluphenazine
  • Methadone
  • Ciprofloxacin
  • Risperidone
  • Doxazosin
  • Eprosartan
  • Tolbutamide
  • Acetazolamide
• Invokana Disease Interactions
  • Liver dysfunction
  • Renal dysfunction
  • Hypotension
  • Infections

Invokana (canagliflozin) has several alternatives for managing type 2 diabetes. Alternatives to Invokana include:

• Metformin
• Other SGLT2 Inhibitors
  • Dapagliflozin (Farxiga)
  • Empagliflozin (Jardiance)
  • Ertugliflozin (Steglatro)
• Sulfonylureas
  • Glimepiride
  • Glyburide
  • Glipizide
• DPP-4 Inhibitors
  • Sitagliptin
  • Saxagliptin
  • Linagliptin
• GLP-1 Receptor Agonists
  • Liraglutide
  • Semaglutide
  • Dulaglutide
• Thiazolidinediones
  • Pioglitazone
  • Rosiglitazone

In the U.S., the cost of Invokana for type 2 diabetes is a significant burden for many Americans. This is especially true for those with limited or no insurance coverage. Facing higher costs, some patients are forced to delay refills or stretch their doses. This puts their type 2 diabetes management at serious risk. At Polar Bear Meds, we recognize these challenges and offer Invokana tablets for diabetes treatment at more affordable prices.

We partner with licensed Canadian pharmacies and offer Invokana at prices up to 80% lower than those of U.S. pharmacies. Additionally, new customers can take advantage of an extra 10% off with our Invokana coupon code “WELCOMEPB10,” without insurance or hidden fees.

When you order Invokana online with us, you can expect delivery within 3-5 days via Xpress Post.

• https://www.Invokana.com/
• https://www.ema.europa.eu/en/medicines/human/EPAR/Invokana
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/204042s026lbl.pdf
• https://www.webmd.com/drugs/Invokana-canagliflozin
• https://reference.medscape.com/drug/Invokana-canagliflozin-999811
• https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b9057d3b-b104-4f09-8a61-c61ef9d4a3f3
• https://www.drugs.com/drug-interactions/canagliflozin,Invokana-index.html?filter=1
• https://www.healthline.com/health/drugs/Invokana-interactions