Levomefolate Calcium

L-Methylfolate

L-Methylfolate is a folate form, also known as vitamin B9, and unlike other vitamin forms, this medication has the ability to quickly absorb the required nutrients in the body. Therefore, doctors usually prescribe this medication to manage folate levels in the body. Low folate levels can caused by various factors such as poor diet, liver disease, alcoholism, etc. Besides this, medication is also used for other conditions like hyperhomocysteinemia (increased levels of amino acid in the blood) and major depressive disorder. It is important to note that this medicine is not an anti-depressant or anti-psychotic medicine, but it may enhance the effects of anti-depressant medications. Lastly, patients should avoid sharing their medicine with other individuals even if they share the same condition. Doing so may increase the risk of side effects, causing life-threatening situations.     

Product Overview

L-Methylfolate is a specialized form of folate, an essential B vitamin, designed to support mental health and overall well-being. Unlike standard folic acid, L-Methylfolate is already in its biologically active form, making it readily usable by the body without requiring conversion. This medication is FDA-approved for specific medical uses, including as a prescription drug to manage conditions related to folate deficiency, such as depression and certain neurological disorders.

L-Methylfolate is available in tablet form, with common strengths including 7.5 mg and 15 mg. It is typically taken once daily, with or without food, as directed by a healthcare practitioner. It is suitable for adults who require improved folate supplementation due to genetic factors or specific health conditions. By helping in the production of neurotransmitters like serotonin, dopamine, and norepinephrine, L-Methylfolate helps regulate mood and support brain function.

Possible side effects include nausea, headache, or allergic reactions. It is important to follow the prescribed dosage recommendations and consult a healthcare provider if any side effects occur. If a dose is missed, take it as soon as possible, but skip it if it’s near the next dose. In case of an overdose, get medical attention immediately. Store L-Methylfolate in a cool, dry place, away from direct light and moisture, and keep it out of reach of children.

What Are the Uses of L-Methylfolate?

This medication is used for the following purposes:

• Folate Deficiency: L-Methylfolate is used to treat folate deficiency, characterized by low levels of folate in the body.
• Major Depressive Disorder: It is often used as an added treatment to improve the effectiveness of anti-depressants.
• Hyperhomocysteinemia Management: This medicine helps reduce the high levels of homocysteine associated with cardiovascular diseases.

What Are the Forms & Strengths of L-Methylfolate?

It is available in an oral tablet form with the following strengths:

• 7.5 mg, and 
• 15 mg

What Are the Recommended Dosage of L-Methylfolate?

The dosage recommendations for L-Methylfolate depend on several factors, including the type and severity of your medical condition and the form of medication you take. Generally, medical professionals prescribe a starting dose and gradually adjust the drug doses as needed. It is important to note that the dosage recommendations below are only for the average dose. So, if you have been prescribed a different dose, do not change it without consulting your medical practitioner.

• Doctors usually advise taking a 7.5 to 15 mg dose of L-Methylfolate orally once a day, with or without food. If you have any concerns, you can talk to a medical professional.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use L-Methylfolate?

• Read the medication guide or PIL (patient information leaflet) carefully to know the detailed medication administration steps. If you have any questions or concerns, ask a healthcare professional.
• Follow the dosage recommendations exactly as mentioned on the prescription label.
• Do not exceed or subceed the doses without consulting a medical expert. Doing so may increase the risk of side effects.
• Take the medication orally with a glass of water with or without food, as your doctor advises.
• Swallow the tablets as a whole.
• Avoid chewing, crushing, splitting, or breaking the tablets. Doing so may release the drug at once. 
• If you are unable to swallow the medicine, consult your healthcare practitioner. They will suggest alternate options that suit your body’s needs.
• Take the medicines at the same time each day to get the most benefit out of it.
• Do not abruptly stop taking your medication without consulting a medical provider. This may cause serious complications in the future. So, complete your course of treatment till the days your doctor has advised.  
• Use the strength of medication that has been prescribed to you by your healthcare provider. Avoid switching brands without consulting a medical expert.
• L-Methylfolate is only a part of the treatment. You may need to include other medicines and psychological counseling if you are taking this medication for depression or schizophrenia. 

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does L-Methylfolate Work?

L-Methylfolate is the active form of folate, a B9 vitamin that plays a crucial role in the body. Unlike regular folic acid, L-Methylfolate is already in its usable form, which means it can be directly utilized by the body without needing conversion. It helps in the production of neurotransmitters (chemical messengers) such as dopamine, serotonin & norepinephrine, which are essential for mood regulation and mental health. L-Methylfolate is often prescribed to individuals who have difficulty converting folic acid due to genetic factors, helping them maintain adequate folate levels and support overall brain function and mood stability.

Important Safety Information for Using L-Methylfolate

What Are the Side Effects of L-Methylfolate?

Common Side Effects of L-Methylfolate: This medication can cause various side effects. However, these reactions are generally temporary and last for a few days to weeks. If you notice any of the following reactions stay for too long or get worse over time, immediately reach out to a medical professional. Common side effects of L-Methylfolate may include:

• Irritability
• Difficulty while concentrating
• Impaired judgment
• Nausea
• Overactivity
• Gas
• Bitter or bad taste
• Not feeling hungry
• Excitement
• Upset stomach
• Allergic reactions

Serious Side Effects of L-Methylfolate: Besides the above common reactions, this medication can also lead to several adverse side effects, causing fatal situations. If you notice any unusual reactions that seem concerning, visit a medical practitioner. Serious side effects of L-Methylfolate may include:

• Anxiety 
• Agitation
• Changes in sleep patterns
• Confusion
• Serious allergic reactions. Its signs may include:
  • Hives
  • Rash
  • Swelling
  • Difficulty breathing
• Unusual hoarseness
• Swelling on the mouth, tongue, lips, face, or throat

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for L-Methylfolate? 

L-Methylfolate can cause severe side effects in certain patients, or it may not be an ideal treatment option for specific populations due to their medical conditions. So, if you are using this medication, you should remain cautious as it has several warnings, which are as follows:

• Vitamin B12 Deficiency Anaemia: This medication should not be used alone to treat conditions like anemia caused by vitamin B12 deficiency. Doing so may increase the risk of worsening your condition. Therefore, always ensure that your vitamin B12 levels are adequately managed alongside this treatment.
• Other Medicines: L-Methylfolate can interact with other medications, potentially affecting their effectiveness or increasing the likelihood of side effects. It is important to inform your medical provider about all medications you are currently taking before beginning treatment with this medication to ensure safe and effective use.

What Are the FDA Boxed Warning for L-Methylfolate?

Boxed warnings, also called black-boxed warnings, are among the most stringent guidelines issued by the FDA. These warnings alert doctors and patients about the harmful effects of a particular drug, which can be life-threatening if overlooked. L-Methylfolate does not have any boxed warnings, meaning it is safe to use. However, its safety is based on the precautions you take. Therefore, if you are taking this drug, follow the instructions provided by your medical practitioner. If you have any concerns or noticed any unusual symptoms, it’s best to consult with an expert.

What Are the L-Methylfolate Precautions?

When considering treatment with L-Methylfolate, patients should discuss every risk and benefit with their medical practitioner. Here are some of the precautions that you can take before using L-Methylfolate:

• Before using this medication, inform your healthcare professional about your allergies or if you are allergic to any of the ingredients present in L-Methylfolate. The product may contain certain inactive components that can cause allergic reactions. 
• When considering treatment with this medication, tell your medical practitioner about your or your family’s medical history, especially of:
  • Anemia
  • Bipolar disorder
  • Tumors in the intestines
  • Vitamin B12 deficiency
• If you are undergoing surgery or any medical procedure, inform your surgeon or healthcare practitioner about the products you use. This includes all prescription drugs, over-the-counter medications, and herbal products. Give your doctor a detailed list of all the substances you take to avoid any potential interactions that could alter the effectiveness of your treatment or increase the chances of developing side effects.
• If you are pregnant or planning to have a baby, you can take this medication if needed, as folic acid is considered safe. It is also included in prenatal vitamin products. Moreover, some spinal cord birth defects may also be prevented by taking an adequate amount of folic acid. However, ask a medical professional to avoid any complications.    
• While folic acid can pass into the breast milk, it will not harm a nursing infant. However, if you are a breastfeeding mother, talk to a medical expert to ensure the safety and effectiveness of L-Methylfolate.
• When taking this medication, make frequent visits to your medical provider. They will check your progress reports and closely monitor the effects of L-Methylfolate.
• Do not use L-Methylfolate alone to treat anemia caused by B12 deficiency. Talk to your healthcare provider for detailed information.
• If your condition does not improve or notice any worsening symptoms while taking this medicine, such as nausea, headaches, or mood changes, reach out to a medical professional. They will adjust your dosage or suggest alternative treatments if necessary.

What Are the Contraindications of L-Methylfolate?

This medication is contraindicated in patients with:

• Hypersensitivity reactions to L-Methylfolate or any of the ingredients involved in its formulation.
• History of intolerance to the supplement.

What If You Missed a Dose of L-Methylfolate?

Generally, it is advisable not to miss any doses of L-Methylfolate, but if someone forgets, they should:

• Take the tablets as soon as possible or whenever they remember.
• If it is almost time for the next dose, omit the missed dose & follow the regular dosing schedule as a medical professional instructed.
• Remember not to take double doses of the prescribed medication just for the sake of making up for the missed dose. This may cause adverse side effects.
• Use medication apps or set reminders on your mobile phone to avoid skipping any doses.
• Take each dose at the same time every day to get the most benefit out of it.
• If patients are still unsure about the missed doses, talk to an expert physician. They will guide each patient and suggest alternate options suiting their body needs.  

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of L-Methylfolate?

While patients are educated enough to know the complications of overdose, there are times when they mistakenly take an excessive amount of L-Methylfolate tablets. In such cases, patients are advised not to panic and instead look for unusual signs like fainting and difficulty breathing. If such symptoms appear, visit the nearest clinic or get medical assistance immediately by calling 911.  

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

How to Store a L-Methylfolate?

• Store the medicine at room temperature and keep it protected from light and moisture.
• Do not keep the medication in moist or damp places like the bathroom or near the sink.
• Do not flush the medicine down the toilet.
• Keep your medicines away from children and pets.
• Store the medication somewhere safe and place safety locks on the container to avoid poisoning your child. There are many products in the market that are not child-resistant.
• Discard the product when not in use.
• Keep the tablets in a dry place.
• Do not use a medication if its expiration date has passed. The expiration date is the last day of the month mentioned on the back of the prescription label or carton.
• You should dispose of the medications in such a way that children and animals cannot consume them, as it may cause accidental overdose and death if someone else consumes them.
• Ask a medical professional how to dispose of the medicine properly without damaging the environment.
• The best way to eliminate unwanted medications is to give them in the medicine take-back program.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

What Medications Interact with L-Methylfolate?

Drug interactions occur when one or more medications are taken simultaneously. These interactions can either raise the risk of developing side effects in certain patients or affect the functioning of one of the drugs. Either way, it results in adverse reactions. Therefore, patients need to be aware of the drugs that may interact with their L-Methylfolate medication. Below are some of the drugs that can interact with L-Methylfolate:

• Capecitabine
• Carbamazepine
• Divalproex sodium
• Eslicarbazepine
• Ethosuximide
• Ethotoin
• Felbamate
• Fluorouracil
• Fosphenytoin
• Lamotrigine
• Mephenytoin
• Mephobarbital
• Methotrexate
• Methsuximide
• Oxcarbazepine
• Pafolacianine
• Pancreatin
• Pancrelipase
• Phenobarbital
• Phensuximide
• Phenytoin
• Primidone
• Rufinamide
• Sulfasalazine
• Valproic acid

[Note: This isn’t a complete list, and there could be other drugs that interact with L-Methylfolate. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the L-Methylfolate Alternatives?

People usually take alternative drugs for many reasons. In some cases, the prescribed medication may not be an ideal option for them due to their medical conditions. On the other hand, they may not achieve the results they are aiming for. Therefore, you should talk to a medical professional before you start a particular treatment or if you want to change your medication. They may help you decide which medication is best suited for you. Some of the alternatives to L-Methylfolate are as follows:

• Availnex
• Axona
• Cerefolin
• Cerefolin Nac
• Denovo
• Deplin 15
• Foltx
• Limbrel
• Metafolbic
• Metanx
• Xyzbac
• Zytaze

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

L-Methylfolate Cost & Coupons

It is important to note that the cost of L-Methylfolate is not the same everywhere. The actual price of these tablets depends on several factors, including your insurance plan, location, and the pharmacies you use. L-Methylfolate, with its therapeutic qualities, can be expensive for certain patients. Here, insurance coverage plays a significant role. You can buy your medication at affordable rates with an insurance coverage plan. However, not all drugs/medications are covered under the insurance plan. If you are residing in America and searching for affordable pharmacies to manage your medication’s cost, reach out to Polar Bear Meds. Here, you can buy L-Methylfolate online from Canada in the USA at discounted rates. Moreover, first-time buyers can use the L-Methylfolate coupon code WELCOMEPB10 to receive a 10% discount on their first order.

Frequently Asked Questions

Can I take L-Methylfolate daily?

Yes, L-Methylfolate can be taken daily, as directed by your healthcare provider. It is often prescribed as a daily supplement to support folate levels, especially in individuals with specific genetic conditions or health needs. Regular intake of this medication ensures consistent support for neurotransmitter production and overall health. However, always follow the dosage and frequency recommended by your medical provider to avoid any potential side effects or interactions with other medications.

Is L-Methylfolate the same as B12?

No, L-Methylfolate and vitamin B12 are not the same. L-Methylfolate is the active form of folate, also known as vitamin B or B9), which is crucial for DNA synthesis and neurotransmitter production. Vitamin B12, on the other hand, is essential for nerve function along with the production of red blood cells. Both vitamins are important for overall health, and they often work together, but they serve different functions in the body and are not interchangeable. So, when considering treatment with this medication, consult a medical professional and discuss every risk and benefit with them.

Is L-Methylfolate good for hair?

L-Methylfolate may indirectly support hair health by contributing to overall nutrient balance and cellular function. As an active form of folate, it helps in the production of DNA and supports cell growth, which can be beneficial for maintaining healthy hair. However, L-Methylfolate is not specifically a hair growth supplement, and its primary benefits are related to brain function and mood regulation rather than direct hair enhancement. If you want supplements for good hair, you can talk to your doctor.

Can I take L-Methylfolate at night?

Yes, L-Methylfolate can be taken at night if that fits your schedule. The time of day does not typically affect the effectiveness of the supplement. However, it’s important to take it consistently at the same time each day, as directed by your healthcare provider. Some people prefer to take it in the morning to align with their routine, but it can be taken at night if that works better for you. Make sure to take each dose at the same time to get the most benefit out of it.

When is the best time to take L-Methylfolate?

The best time to take L-Methylfolate is whenever it fits best into your daily routine, as long as you take it consistently at the same time each day. Some individuals prefer taking it in the morning, especially if they experience any mild energizing effects. However, it can also be taken with or without food, at any time of day, according to your preference or your healthcare provider’s recommendation.

Our Guarantee

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