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Linzess

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Product Details

Description

Linzess (linaclotide) is a prescription medicine used to manage irritable bowel syndrome with constipation and chronic idiopathic constipation. It belongs to the drug class known as guanylate cyclase-C agonists, which helps stimulate intestinal fluid secretion and promote more regular bowel movements. Taken orally in capsule form, Linzess works locally in the gut, avoiding absorption into the bloodstream, and thus minimizes systemic side effects. It may also ease abdominal discomfort by reducing nerve sensitivity in the digestive tract. Linzess is typically taken once daily on an empty stomach and should only be used under medical supervision. You can order Linzess online with a valid prescription.

Generic NameLinaclotide
Brand NameLinzess
FormsCapsules
Strengths Available72 mcg & 145 mcg & 290 mcg
Packaging
Requires PrescriptionPrescription only (Rx)
Ships to USAYes
Uses and Benefits

Linzess is commonly used to treat constipation in people suffering from certain bowel diseases, such as irritable bowel syndrome with constipation:

  • Irritable bowel syndrome with constipation (IBS-C)
  • Chronic idiopathic constipation (CIC)
  • Functional constipation (FC)

Benefits of Linzess

  • This prescription constipation medication increases fluid secretion in the intestines, making stools softer & easier to pass.
  • It helps alleviate symptoms such as bloating, straining, and abdominal pain.
  • It works locally in the intestine, reducing the risk of widespread side effects.
Dosage

The recommended dosage of Linzess varies among patients. Follow your doctor’s instructions and avoid making any changes to your dose without consulting them first. Typical Linzess dosage includes:

Dosage of Linzess for IBS-C

  • Take 290 mcg orally once daily on an empty stomach.

Dosage of Linzess for CIC

  • Take 145 mcg orally daily.

Pediatric Dosage of Linzess for Functional Constipation

  • Take 72 mcg orally once a day.
Usage Guide
  • Linzess is typically taken once daily on an empty stomach, at least thirty minutes before the morning meal, to ensure optimal effectiveness.
  • Swallow this gut health medication as a whole with a full glass of water. If you have trouble swallowing it whole, you may open it and sprinkle its contents into applesauce (a teaspoonful) or mix it with one ounce of water and swallow it immediately. Do not store the mixture for future use, and do not chew the mixture.
  • This constipation relief medication may also be given through a nasogastric or gastric tube. If you are administering it through a feeding tube, ensure that you or your caregiver understands how to prepare and use Linzess properly.
  • It may take up to two weeks to notice the full benefits associated with using this medication. Continue using it as directed and inform your doctor if your symptoms do not get better.
How It Works

Linzess works by activating guanylate cyclase-C receptors in the intestines, which increases fluid secretion and stimulates bowel movements, helping to soften stools and ease constipation. Additionally, Linzess helps reduce sensitivity in pain-sensing nerves in the gut, which can alleviate abdominal discomfort commonly associated with IBS-C. By regulating bowel movements and decreasing gut sensitivity, Linzess can significantly improve symptoms for individuals struggling with chronic constipation-related conditions.

Side Effects

Common Linzess side effects may include:

  • Diarrhea
  • Flatulence
  • Stomach pain
  • Feeling of fullness
  • Pressure in the stomach

Serious side effects (rare):

  • Severe allergic reactions, including a racing heart, swollen lymph nodes, facial swelling, trouble swallowing, hives, or stomach cramps.
  • Diarrhea, sometimes severe.
  • Unsteadiness
  • Acute leg cramps
  • Irregular heartbeats, such as palpitations or arrhythmias

Note: Talk to your healthcare provider if you experience any severe symptoms or unusual skin changes.

Warnings
  • Allergy: Patients with an allergy to Linzess, linaclotide, or any other ingredient present in the product should not use it, as it can cause harm.
  • Contraindication: Linzess is contraindicated in patients with known or suspected mechanical gastrointestinal obstruction.
  • Not for Children Under 2 Years of Age: Linzess can cause severe diarrhea in pediatric patients under 2 years of age, which may result in severe dehydration; therefore, it is not recommended for use in patients of this age group.
  • Bowel Obstruction: Do not take Linzess if you have a blockage in the gut, as it may worsen your condition.

Severe Symptoms: Discontinue using Linzess and call your doctor at once if you experience severe or persistent diarrhea, severe abdominal pain, or melena and hematochezia.

Safety Guide
  • Pregnancy: The effects of Linzess on pregnancy are not fully understood, so consult your healthcare provider before use. They will weigh the risks associated with its use against the good it can do to help determine if Linzess is safe for you to take.
  • Breastfeeding: The safety of this prescription IBS medication for use during breastfeeding is not known. Tell your healthcare provider if you are breastfeeding or plan to breastfeed an infant while using this medication for IBS-C.
  • Pediatric Use: The safety and efficacy of Linzess has not been established in pediatric patients under 6 years of age with functional constipation, or individuals under 18 years of age with IBS-C.
Missed Dose

If you miss a dose of Linzess, administer it as soon as possible. If it is almost time for your next Linzess dose, skip the missed dose and take the next dose at your regular time. Do not take a double dose to make up for the missed dose.

Overdose

Overdosing on Linzess can increase the risk of severe side effects, such as intense diarrhea, dehydration, severe stomach pain, and electrolyte imbalances. If you or someone has taken an overdose of Linzess, seek immediate medical attention by calling your doctor or the poison control helpline.

Storage Guide

Following proper storage guidelines is essential to maintain the potency of the drug you are using.

  • You should keep Linzess (linaclotide) in its original packaging at room temperature (20°C to 25°C) to protect it from excessive heat and light.
  • Avoid storing it in humid environments, like bathrooms or areas prone to moisture, as high levels of moisture can cause harm to certain medications. Keep it in a dry place.
  • Keep Linzess in a secure place, away from the sight and reach of children and pets, to prevent accidental ingestion.
Interactions

Certain medications may interact with Linzess, affecting its effectiveness. Discuss all products you currently use or plan to use with your doctor, including those used in conjunction with this medication. Potential drug interactions of Linzess include:

  • Albuterol
  • Amlodipine
  • Aspirin
  • Atorvastatin
  • Benztropine
  • Bismuth subsalicylate
  • Gabapentin
  • Lomotil
  • Loperamide
  • Oxybutynin
  • Scopolamine
  • Tramadol
Alternatives

While Linzess is effective for many patients with IBS-C and chronic constipation, alternatives may be recommended based on individual needs. These may include:

  • Amitiza (lubiprostone)
  • Bentyl
  • Ibsrela (tenapanor)
  • MiraLAX (polyethylene glycol 3350)
  • Motegrity (prucalopride)
  • Trulance (plecanatide)
Cost & Coupons

Why Buy Linzess from Polar Bear Meds?

At Polar Bear Meds, we’re dedicated to providing affordable and accessible prescription medications, such as Linzess, to patients across the USA. Our prices are substantially lower than standard USA pharmacy retail rates without compromising on safety or quality. Every order is sourced exclusively from licensed and trusted pharmacies and undergoes complete prescription verification to ensure compliance and authenticity. Enjoy discreet, trackable shipping to all states, with ongoing refill support for your treatment. Our helpful customer service team is always here to assist you.

Cost & Coupons

Order Linzess directly from Canada to your doorstep in the USA with ease. You can also save more by using the coupon code “WELCOMEPB10” to get an extra 10% off on your first purchase. There are no hidden processing fees or additional charges, as we believe in complete transparency. Looking to save even more? Take advantage of our referral program and earn a $20 credit every time you refer a friend or a family member. Your friend will also receive a $20 credit, so everyone wins. Additionally, for every 10 verified referrals, you’ll receive an extra $100 credit as a token of appreciation for sharing with others.

FAQ

Guarantee

AtPolar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently buy Linzess from Canada at a substantial cost, call us at 1-888-779-2193 toll-free.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn

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