Livalo

Livalo contains the active drug Pitavastatin and belongs to a class of drugs called statins. It is approved by the FDA to treat high cholesterol, primarily in adults and children aged eight and older. It belongs to the class of drugs known as statins, which work by inhibiting an enzyme that aids in cholesterol production. The typical dosage for adults ranges from 2-4 mg daily, while children with heterozygous familial hypercholesterolemia start at 2 mg daily. It’s important to take Livalo as prescribed by a doctor, who will adjust the dosage based on individual needs and cholesterol levels. Common side effects include muscle pain, diarrhea, and skin rash. Always consult a healthcare provider before starting Livalo to get the maximum benefit from your medication.

Livalo, a statin medication, is prescribed for managing primary hyperlipidemia and mixed dyslipidemia in adults, as well as heterozygous familial hypercholesterolemia in children aged eight years and older. It helps lower the risk of heart disease, heart attack, or stroke by reducing high cholesterol levels. The drug is available in oral tablet form with strengths of 1 mg, 2 mg, and 4 mg. For adults with high cholesterol, the typical dosage starts at 2 mg daily and can be increased up to 4 mg based on the doctor’s assessment after four weeks. Children with heterozygous familial hypercholesterolemia usually begin with a 2 mg dose, which can be adjusted between 2 mg and 4 mg once daily.

Livalo is intended for long-term use under medical supervision. It is most effective when combined with a low-cholesterol diet. The medication works by blocking an enzyme involved in cholesterol production, thereby reducing cholesterol levels in the blood. Patients are advised to take Livalo by mouth, with or without food, following their doctor’s instructions. Dosage adjustments may be necessary based on the patient’s health condition, response to treatment, and other medications being taken.

Common side effects of Livalo include diarrhea, muscle pain, skin rash, headache, joint pain, and flu symptoms. More serious side effects, though rare, can consist of severe eye symptoms, heart issues, severe headache symptoms, and allergic reactions. Patients should inform their healthcare provider of any side effects or concerns while taking Livalo. Pitavastatin is used together with diet, weight loss, and exercise to reduce the amount of bad cholesterol in your body and increase the amount of good cholesterol. It’s also important to discuss any potential drug interactions and precautions with a healthcare provider before starting treatment with Livalo.

Targeted Treatment

• It is approved to treat/lower high cholesterol (in adults and children eight years or older)

Benefits

• Lower the risk for heart disease such as heart attack or stroke
• Primary hyperlipidemia (in adults)
• Mixed dyslipidemia (in adults)
• HeFH or Heterozygous familial hypercholesterolemia (in children ages eight years and older)

[Note: Do not take Escitalopram without consulting your doctor. They will determine whether you need this medication based on your conditions.]

Forms & Strengths

Form: Oral Tablets (to swallow)

Strengths: 1 mg, 2 mg, 4 mg

Recommended Dosages

For High Cholesterol

Dosage Range: 2–4 mg daily

Starting Dose: 2 mg daily

After 4 Weeks: The doctor will check the levels of your cholesterol. If Cholesterol is still high, they will increase your dose.

Maximum Dose: 4 mg daily

For Children with HeFH (8 Years & Older)

Starting Dose: 2 mg once daily

Maintenance Dose: 2 mg to 4 mg once daily

Maximum Dose: 4 mg once daily

For Long-term Treatment

Livalo is designed for long-term use. If your doctor finds that Livalo is suitable and effective for you, you will likely need to take it for an extended period.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

• Usually, your doctor will begin by giving you a low dose of the medication. Over time, they will adjust this dose until it’s just right for you. The goal is to find the smallest dose that still gives you the necessary benefits.
• The doses mentioned below are typical for adults, but your doctor will give you a specific dose that’s tailored to your situation.
• It’s important to follow your doctor’s instructions when it comes to dosage.
• Take Livalo by mouth, with or without food, as your doctor instructs, usually once a day.
• Your dosage depends on your health condition, how you respond to the treatment, and any other medications you’re taking.
• Make sure to tell your doctor and pharmacist about all the products you’re using, including prescription drugs, over-the-counter drugs, and herbal products.
• If you’re also taking certain cholesterol-lowering drugs like cholestyramine or colestipol, take Livalo either 1 hour before or 4 hours after these medications. This is because they can interfere with the absorption of Livalo.
• For the best results, take this medication regularly and at the same time each day.
• Continue taking Livalo even if you feel well, as most people with high cholesterol or triglycerides don’t feel sick.
• It’s crucial to keep following your doctor’s advice about diet and exercise. It might take up to 4 weeks to experience the full benefits of this drug.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

Livalo is a medication used to treat specific types of high cholesterol in both adults and children, and it’s most effective when combined with a diet low in cholesterol. Cholesterol is a fatty substance naturally present in your body. It’s produced by your liver and can also be found in foods like cheese, eggs, and meat. While cholesterol is essential for creating hormones and vitamins, having too much of it can lead to heart disease. Livalo falls under a category of medications known as statins. Its primary function is to inhibit a specific enzyme (a kind of protein) that aids in the production of cholesterol in your body. By blocking this enzyme, Livalo effectively reduces your cholesterol levels.

Common side effects of Livalo may include:

• Diarrhea
• Muscle pain
• Skin rash
• Headache
• Joint pain
• Stuffy or runny nose
• Back pain
• Sore throat
• Pain in your arms and legs
• Constipation
• Flu symptoms

Mild Side Effects of Livalo may include:

• Arm or leg pain
• Muscle pain
• Diarrhea
• Headache
• Joint pain
• Back pain
• Constipation
• Mild allergic reaction

Adverse/Serious Side Effects of Livalo may include:

• Serious eye symptoms such as:
  • Eye pain or swelling
  • Tunnel vision
  • Seeing halos around lights
  • Sudden vision loss
  • Blurred vision
• Serious heart symptoms such as:
  • Fluttering in your chest
  • Sudden dizziness
  • Fast, pounding, or irregular heartbeats
  • Shortness of breath
  • Lightheadedness
  • Passing out
• Severe headache symptoms may include:
  • Slurred speech
  • Tremors
  • Arm or leg weakness
  • Trouble walking
  • Loss of coordination
  • High fever
  • Feeling unsteady
  • Very stiff muscles
  • Profuse sweating
  • Confusion

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Before starting Livalo, discuss your medical history with your healthcare provider. Livalo might not be suitable for you if you have certain health conditions or other factors that could affect your well-being.

• Muscle and Kidney Damage: Before you start taking Livalo, inform your doctor if you have any kidney issues. Livalo can cause muscle and kidney damage with intense pain. On the other hand, if you have kidney problems, your risk of this side effect may be higher. Your doctor might adjust your dosage differently than the standard prescription. They will also advise you on whether it’s safe for you to take Livalo.
• Liver problems: If you have any liver issues, such as liver disease, it’s essential to inform your doctor before starting treatment with Livalo. Livalo can cause liver problems as a side effect. Therefore, if you already have liver conditions, your doctor will usually not recommend Livalo as a treatment option. 
• Muscle Weakness (Autoimmune): In rare instances, some individuals taking Livalo (Pitavastatin) may experience autoimmune-mediated muscle weakness, where the body’s immune system attacks its own muscles. If you notice severe muscle weakness, it’s important to inform your healthcare provider. You may need to discontinue the use of Livalo (Pitavastatin). 
• Low Level of Thyroid Hormone: If you have low thyroid hormone levels that are not being treated, inform your doctor before starting Livalo. Livalo can cause muscle damage and pain, and having low thyroid hormone levels may increase your risk for this side effect. Your doctor will determine if it’s safe for you to take Livalo based on your health condition.
• Allergic Reaction: If you have experienced an allergic reaction to Livalo or any of its components in the past, it is likely that your healthcare provider will not prescribe this medication for you. It’s important to discuss with your doctor about alternative medications that may be more suitable for your condition. 
• Heavy Alcohol Use: Livalo can lead to liver issues. If you have a history of consuming a lot of alcohol, you may be more at risk for these liver problems. It’s essential to inform your doctor about your alcohol consumption history before starting Livalo. Your doctor will then determine if it’s safe for you to use this medication.
• Birth Defects: Livalo (Pitavastatin) is known to cause severe congenital disabilities or even lead to infant death. If you’re planning to become pregnant, are already pregnant, or are breastfeeding, it’s crucial to inform your healthcare provider. Your provider can assist you in exploring alternative options for managing your cholesterol levels. 
• High Blood Sugar: Pitavastatin can increase your blood glucose (blood sugar) levels. If you observe a rise in your blood sugar while taking this medication, inform your healthcare provider. They may adjust the dosage or consider alternative medicines based on your condition.

• Pregnancy: The safety of using Livalo during pregnancy is not known, as there have not been studies on its use during pregnancy. It is generally advised to avoid taking Livalo if you are pregnant due to its effects on the body. If you find out you are pregnant while taking Livalo, you should stop taking the medication and inform your doctor immediately. If you are pregnant or planning to become pregnant while on Livalo, it’s important to discuss alternative treatment options with your doctor.
• Breastfeeding: It may not be safe to breastfeed while taking the medication Livalo. The drug’s presence in breast milk is unknown, but other similar medications, known as statins, are known to pass into breast milk. Livalo could potentially cause side effects in a breastfed baby. Therefore, it is recommended not to breastfeed while taking this medication. If you have questions about feeding your child while on Livalo, it’s crucial to discuss them with your doctor.
• Birth Control Pills: It’s important to note that Livalo should not be taken during pregnancy. If you are sexually active and there is a possibility of pregnancy, discuss your birth control options with your doctor while using Livalo. For further details on using Livalo during pregnancy, refer to the “pregnancy” section provided earlier.
• For Females taking Livalo: If you can become pregnant, you should use birth control while taking Livalo. It’s important to discuss with your doctor the best birth control options for you.
• For Males taking Livalo: The manufacturer of Livalo has not provided specific birth control recommendations for males taking the drug. If you’re taking Livalo and are sexually active with a partner who could become pregnant, you should consult with your doctor about your birth control needs.

• Nursing mothers
• Active liver disease
• Known hypersensitivity to product components
• Co-administration with cyclosporine
• Women who are pregnant or may become pregnant

• If you forget to take a dose of Livalo, take it as soon as you remember.
• If more than 12 hours have passed since the missed dose, it’s best to skip it and continue with your regular dosing schedule.
• Do not take extra doses to compensate for the missed one, as this could increase your risk of experiencing side effects from Livalo.
• If you’re unsure about whether to take a missed dose or skip it, consult your doctor or pharmacist for guidance.
• To prevent missing doses in the future, consider using a medication reminder.
• This could be setting an alarm, using a timer, or downloading a reminder app on your phone.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

• It’s crucial to use Livalo only as prescribed by your doctor. Taking more than recommended can lead to adverse effects or overdose.
• If you suspect you’ve taken an excessive amount of Livalo, contact your doctor immediately.
• You can also reach out to the American Association of Poison Control Centers for guidance.
• In case of severe symptoms, call 911 or your local emergency number, or head to the nearest emergency room without delay.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

• The effectiveness of a medication can depend on various factors, including how and where it is stored.
• Livalo tablets are recommended to be stored at room temperature, between 59°F and 86°F (15°C and 30°C).
• The tablets should be kept in a tightly sealed container and away from light.
• It’s important to avoid storing this medication in areas that might be damp or wet, such as bathrooms.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Before you begin taking Livalo, it’s essential to inform your healthcare provider and pharmacist about all the medications you are currently using. This includes prescription drugs, over-the-counter medications, and any other substances you take. Sharing this information can help prevent potential interactions between Livalo and other substances you are using.

• Drug Interaction: Below is a list of drug groups or drug names that can interact with Livalo. It is not the complete list of drugs; consult your primary caregiver for more information.
  • Autoimmune Disease Drugs: cyclosporine (Gengraf, Neoral, Sandimmune)
  • itraconazole (Sporanox, Tolsura)
  • Antibiotic Medicines: erythromycin (Ery-Tab, Eryc, EES, EryPed)
  • digoxin (Lanoxin)
  • Cholesterol Lowering Drugs: Fibrates such as fenofibrate (Antara, Trilipix, Lipofen, others) and gemfibrozil (Lopid)
  • Tuberculosis Drugs: rifampin (Rimactane, Rifadin)
  • atazanavir (Reyetaz)
  • niacin (Niacor)
  • Gout Treating Drugs: colchicine (Mitigare, Colcrys, Lodoco, Gloperba)
• Interaction with Alcohol: Livalo does not directly interact with alcohol. But both Livalo and alcohol can cause similar side effects like headaches, nausea, and diarrhea. Therefore, consuming alcohol while taking Livalo might increase the likelihood of experiencing these side effects. 

Additionally, Livalo has the potential to cause liver damage, and heavy alcohol consumption can also lead to liver problems. As a result, drinking large amounts of alcohol while on Livalo could elevate the risk of liver damage. If you’re considering drinking alcohol while taking Livalo, it’s important to discuss this with your healthcare provider or pharmacist to ensure your safety.

• Red Yeast Rice: Avoid taking red yeast rice products while on Pitavastatin medication. Some red yeast rice products contain a statin known as lovastatin. Combining Pitavastatin with red yeast rice products can significantly increase the risk of developing severe muscle and liver issues.

[Note: This isn’t a complete list, and there could be other drugs that interact with Livalo. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

• Vascepa (icosapent ethyl)
• Juxtapid (lomitapide)
• Advicor (lovastatin)
• Zetia (ezetimibe)
• Lovastatin
• Lescol XL (fluvastatin)
• Lovaza (omega-3-acid esters)
• Pravastatin
• Welchol (colestipol)
• Crestor (rosuvastatin)
• Nexletol (bempedoic acid)
• Lopid (gemfibrozil)
• Lipitor (atorvastatin)
• Tricor (fenofibrate)
• Niaspan (niacin ER)
• Questran (cholestyramine)
• Repatha (evolocumab)
• Zocor (simvastatin)
• Praluent (alirocumab)
• Leqvio (inclisiran)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

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