Polarbearmeds - Home
Mysimba - Image 1

Mysimba

No packages found
price-match-guarantee

Price Match Guarantee

We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More

How to Order

Ordering your medication online is simple and convenient.

STEP 01

Select the prescribed dosage and quantity, then proceed to checkout.

STEP 02

Sign in or create a new account.

STEP 03

Upload your prescription.

STEP 04

Complete your purchase by processing the payment.

Shipping takes approximately 3-5 business days.

5 Star Excellence award from Shopper Approved

Product Details

What is Mysimba?

What is Mysimba?

Mysimba is a prescription medicine used by adults who are obese or overweight with weight-related health conditions. The medication is a combination of bupropion and naltrexone, available as tablets in 90 mg/8 mg strengths. It is used along with a reduced-calorie diet and increased physical activity to support weight loss.

Quick Facts About Mysimba

Quick Facts About Mysimba

Product NameMysimba
Active IngredientBupropion hydrochloride and Naltrexone hydrochloride
Drug ClassAnti-obesity medication
Available FormsOral tablets
Strengths Available90 mg/8 mg
Routes of AdministrationTaken by mouth
Mysimba UsesHelps in weight management in adults (18+) with:
Obesity (BMI ≥30) or overweight (BMI ≥27)

Overweight with a weight-related condition (e.g., Type 2 diabetes)
Mysimba StorageStore at 20°C to 25°C (68°F to 77°F), excursions permitted up to 30 °C.
Pregnancy and BreastfeedingConsult a doctor
Legal StatusRx only
Black Box WarningSuicidal thoughts and reactions

Neuropsychiatric reactions

← Swipe to see more →

Information: Mysimba is an FDA-approved medicine under the brand name Contrave in the United States. Both brands contain the same ingredients: Bupropion hydrochloride and Naltrexone hydrochloride, used in weight management.

How Does Mysimba Work?

How Does Mysimba Work?

Mysimba, a combination of bupropion and naltrexone, acts on brain centers involved in hunger and reward. The components influence the brain’s reward system, which is associated with the pleasurable effects of eating. When used together, Mysimba helps reduce hunger and decrease the amount of food patients eat. It may help improve energy levels, making it easier to follow a calorie-controlled diet.

What Are the Uses of Mysimba (bupropion/naltrexone)?

What Are the Uses of Mysimba (bupropion/naltrexone)?

Mysimba contains bupropion and naltrexone, a combination that helps manage body weight in adults. Mysimba uses are as follows:

  • For adults with obesity (BMI ≥30).
  • For people who are overweight, having a body mass index (BMI) ≥ 27, and also patients having weight-related health conditions such as high blood pressure, diabetes, and cardiovascular disease.
What Are the Adverse Effects of Mysimba?

What Are the Adverse Effects of Mysimba?

The medication may cause some unwanted effects that require emergency help. Mysimba side effects: less common, more common, rare, and Frequency unknown are as follows:

Less Common Side EffectsMore Common Side EffectsSerious Side EffectsFrequency Unknown
Frequent urge to urinateDizzinessNauseaChills
Bladder painBlurred visionDiscomfort or chest painAnxiety
Lower back or side painHeadacheVomitingAggression
Cloudy or bloody urineNervousness or fearSweatingLoosening or blistering of the skin
Trembling of hands or feetLoss of interest or pleasurePain or discomfort in the arms, jaw, neck, or backDiarrhea
Burning, difficult, or painful urinationPounding in the earsSuicidal thoughtsDry mouth
Irregular or pounding heartbeatTrouble concentratingBehavioral changesHives or itching

← Swipe to see more →

What Are the Precautions of Mysimba?

What Are the Precautions of Mysimba?

It is crucial that your doctor check your progress at regular visits to ensure that the medicine is working properly without causing unnecessary side effects. Keep the following Mysimba precautions in mind before taking the medication.

  • Increase in heart rate and blood pressure
    • Taking the Mysimba dose may elevate systolic or diastolic blood pressure or heart rate.
    • Blood pressure and pulse should be monitored during treatment.
    • Use cautiously in patients with controlled cardiovascular disease or hypertension.
  • Hypoglycemia in patients with type 2 diabetes
    • Patients using insulin or insulin secretagogues should take the medicine cautiously, as weight loss may increase the risk of hypoglycemia.
    • Blood glucose levels should be monitored regularly.
  • Hepatotoxicity
    • Patients with hepatic impairment must use the medicine with caution.
    • Contraindicated in severe hepatic impairment. Use caution in mild to moderate hepatic impairment. Dose adjustment required in moderate hepatic impairment.
  • Activation of mania
    • Use with caution in patients with bipolar disorder.
    • Antidepressant component may activate mania in bipolar disorder.
  • Neuropsychiatric reactions
    • This may cause mood changes, agitation, anxiety, insomnia, or behavioural changes.
    • Use carefully in patients with a psychiatric history.
Mysimba Black Box Warning

Mysimba Black Box Warning

Mysimba box warning - Mysimba tablets have an increased risk of:

  • Suicidal thoughts and behavior in children, adolescents, and young adults.
Mysimba Dosage Guide

Mysimba Dosage Guide

Patients who are obese or overweight with weight-related health conditions should keep the following Mysimba dosage guide in mind.

WeekMorning DoseEvening DoseTotal Tablets Per Day
Week 11-1
Week 2112
Week 3213
Week 4 onwards224

← Swipe to see more →

Information: Your doctor should be aware of your dosing schedule. Do not change your dose unless your doctor directs you to do so.

What Are the Alternatives to Mysimba?

What Are the Alternatives to Mysimba?

Use the following Mysimba alternatives for weight management only under your healthcare professional's supervision.

  • Qsymia
  • Saxenda
  • Wegovy
  • Zepbound
  • Xenical

The above substitutes are approved along with the calorie-controlled diet and increased physical activity. Continue regular follow-up visits with your doctor.

What Happens If You Overdose on Mysimba?

What Happens If You Overdose on Mysimba?

Seek emergency medical help in case of Mysimba overdose.

  • Hallucinations
  • Seizures
  • Severe confusion
  • Loss of consciousness
  • Rapid heartbeat
What Happens If You Miss a Mysimba Dose?

What Happens If You Miss a Mysimba Dose?

  • If you miss a Mysimba dose, go back to your regular dosing schedule.
  • Skip the missed dose.
  • Do not double the dose.
Who Should Not Take Mysimba?

Who Should Not Take Mysimba?

Mysimba may not be suitable for certain patients due to increased health risks. The following are Mysimba contraindications:

  • Use of other bupropion products
  • Uncontrolled hypertension
  • Seizure disorders
  • Allergic to any of the Mysimba ingredients
  • Chronic opioid use
  • During or within 14 days of taking MAO (monoamine oxidase) inhibitors
How to Store Mysimba?

How to Store Mysimba?

Mysimba storage guidelines are important to understand for your safety.

  • Store the medicine in a closed container.
  • Store at 20°C to 25°C (68°F to 77°F).
  • Keep out of reach of children and pets.
  • Do not keep the tablets in the bathroom.
What Drugs Interact with Mysimba?

What Drugs Interact with Mysimba?

There are several medicines that should not be used together to avoid serious complications. The following list of Mysimba interactions is not complete. Consult your doctor for the full list of interactions.

  • Alphaprodine
  • Bromopride
  • Codeine
  • Anileridine
  • Fentanyl
  • Linezolid
  • Diphenoxylate
  • Butorphanol
  • Diacetylmorphine
  • Meperidine
  • Morphine
  • Opium
  • Oxycodone
  • Rasagiline

Mysimba blocks opioid receptors; opioid use may cause withdrawal.

Why Buy Mysimba Online from Polar Bear Meds?

Why Buy Mysimba Online from Polar Bear Meds?

Obesity or body weight management medications may be costly when purchased from local U.S. pharmacies. At Polar Bear Meds, we help you access your prescribed medications at more affordable prices by sourcing them through fully licensed Canadian and international pharmacy partners.

When you choose to buy Mysimba online from Polar Bear Meds, you may benefit from significantly lower pricing than at many U.S. retail pharmacies.

Here’s why patients trust Polar Bear Meds for their Mysimba prescription:

  • Competitive pricing
  • Exclusive savings opportunities, including a Mysimba coupon code for additional discounts on your first order
  • Fast and secure shipping, with most orders delivered within 3–5 business days via reliable postal services (Xpress Post)
  • Convenient online ordering process, allowing you to refill your body weight management medications from the comfort of your home

At Polar Bear Meds, your safety and satisfaction come first. Every order is processed through licensed pharmacy partners to ensure you receive authentic Mysimba medicine as prescribed by your healthcare professional. If you are seeking a trusted, affordable way to buy Mysimba online, Polar Bear Meds offers a secure and cost-effective solution according to your needs.

Important Disclaimer

Important Disclaimer

The information provided about Mysimba (bupropion/naltrexone) is for informational and educational purposes only and is not intended to replace professional medical advice, treatment, or diagnosis. Mysimba is a prescription-based medicine and should be used only under the supervision of a pharmacist, healthcare provider, or doctor. Always consult your doctor before changing or stopping your Mysimba dosage.

Mysimba FAQs

Mysimba FAQs

Dr. Jackson Miller

Medically Reviewed by Dr. Jackson Miller (M.D)

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn

Learn more about Mysimba and related topics