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We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More
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Select the prescribed dosage and quantity, then proceed to checkout.
Sign in or create a new account.
Upload your prescription.
Complete your purchase by processing the payment.
Shipping takes approximately 3-5 business days.
Naltrexone Hydrochloride is a prescription medication used to treat OUD (Opioid Use Disorder) and AUD (Alcohol Use Disorder) in adults. It works as an opioid receptor antagonist, which means it blocks the effects of opioids in the brain and may help reduce alcohol cravings.
Naltrexone tablets do not produce opioid-like effects and are not habit-forming. This medication should be taken under medical supervision as part of a comprehensive treatment program that includes behavioral support and counseling.
Naltrexone is available in tablet and injection forms. Currently, our pharmacy provides only a 50 mg oral tablet. Many patients purchase this medication from licensed Canadian pharmacies to save on costs with a valid prescription.
| Category | Details |
|---|---|
| Brand Names | Revia (oral tablets), Vivitrol (extended‑release injection) |
| Generic Name | Naltrexone Hydrochloride |
| Drug Class | Opioid antagonist |
| Prescription Required | Yes, must be prescribed by a licensed healthcare provider |
| FDA‑Approved Indications | OUD (Opioid Use Disorder); AUD (Alcohol Use Disorder) |
| Dosage Forms | Oral tablet: 50 mg; Injectable suspension: 380 mg (monthly intramuscular injection) |
| Important Safety Notes | Patient must be opioid‑free for 7–10 days before starting; risk of hepatotoxicity at high doses; not for patients with liver failure or acute hepatitis |
| Common Side Effects | Nausea, headache, dizziness, fatigue, insomnia, anxiety |
| Monitoring | Liver function tests before and during treatment; confirm opioid abstinence prior to initiation |
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Naltrexone Hydrochloride 50 mg tablets are FDA-approved for:
Naltrexone Hydrochloride can cause side effects and may not be appropriate for everyone. Important risks include:
Before taking Naltrexone, inform your healthcare provider about your medical history and all medications you use. Important precautions include:
Naltrexone Hydrochloride may cause side effects, which can vary by individual. Most of them are mild, but some are serious and require medical attention. Below are some of the Naltrexone side effects:
| Common Side Effects of Naltrexone tablets | Rare or Serious Side Effects of Naltrexone tablets |
|---|---|
| Nausea or vomiting | Liver injury or hepatitis (yellowing of skin/eyes, dark urine) |
| Diarrhea or abdominal pain | Severe allergic reactions (rash, itching, swelling of face or throat) |
| Headache | Severe depression or suicidal thoughts |
| Dizziness | Severe abdominal pain |
| Fatigue or weakness | Signs of opioid withdrawal if opioids are taken |
| Anxiety or nervousness | Abnormal liver function tests |
| Sleep problems (insomnia) | — |
| Muscle or joint pain | — |
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This is not a complete list of side effects. If you experience any unusual or severe symptoms, contact your provider immediately.
Naltrexone Hydrochloride (HCl) blocks the effects of opioids in the brain, including feelings of euphoria or pain relief.
Naltrexone works by preventing the pleasurable effects of certain substances, supporting recovery, and helping patients maintain abstinence.
Following these instructions helps ensure you are taking Naltrexone correctly for its intended use.
Follow this Naltrexone Hydrochloride dosing schedule for different medical conditions:
| Indication | Initial Dose | Maintenance Dose | Key Notes |
|---|---|---|---|
| Alcohol Dependence | No initial dose required | 50 mg once daily | Used as part of a comprehensive treatment program for alcohol dependence |
| Opioid Dependence | 25 mg once daily (initial test dose) | 50 mg once daily | Patient must be opioid‑free for 7–10 days to avoid precipitated withdrawal |
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Always follow the exact Naltrexone dosage prescribed by your healthcare professional.
Taking more Naltrexone than prescribed may increase the risk of side effects and require medical attention.
Possible effects of a Naltrexone overdose may include:
There is limited experience with Naltrexone overdose in humans, and no specific antidote is available. Treatment focuses on monitoring symptoms and providing supportive medical care as needed. If you suspect a Naltrexone overdose, contact your provider or a poison control center immediately.
Follow these Naltrexone Hydrochloride storage guidelines to maintain the medication’s effectiveness and safety:
If Naltrexone Hydrochloride 50 mg is unavailable, other brand medications may be used under medical supervision. The alternatives to Naltrexone Hydrochloride tablets include:
Other Naltrexone Hydrochloride Alternatives for Opioid Use Disorder (OUD)
Other Naltrexone Hydrochloride Alternatives for Alcohol Use Disorder (AUD)
Naltrexone Hydrochloride may interact with other medicines. You should always tell your doctor about all drugs or supplements you are taking.
| Drug Category | Drug Examples | Naltrexone Interaction Note |
|---|---|---|
| Opioid Analgesics | Morphine, Oxycodone, Hydrocodone, Codeine, Fentanyl, Tramadol, Methadone | Naltrexone blocks opioid receptors, making these drugs ineffective and causing sudden, severe withdrawal if opioids are present. |
| Opioid‑Containing Cough/Cold Preparations | Codeine‑based syrups | Ineffective for cough relief; risk of withdrawal symptoms. |
| Opioid Dependence Treatments | Buprenorphine, Methadone | Naltrexone antagonizes their effects; it can precipitate withdrawal. |
| Hepatotoxic Drugs | Isoniazid, Acetaminophen (high doses), Amiodarone | Increased risk of liver injury when combined with Naltrexone. |
| Other CNS Depressants | Alcohol, Sedatives, Benzodiazepines | May increase dizziness or drowsiness; caution advised |
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Many patients choose to order Naltrexone Hydrochloride from Canada because the cost is often much lower than U.S. retail prices. At Polar Bear Meds, we source Naltrexone Hydrochloride 50 mg tablets from a trusted network of licensed Canadian and international pharmacies that comply with strict safety regulations. When you buy Naltrexone Hydrochloride online from our pharmacy, you save up to 80% compared with U.S. retail rates.
Plus, if you are a first-time buyer on our website, you can apply our Naltrexone Hydrochloride coupon code “WELCOMEPB10” to get 10% more discount. You can also expect your Naltrexone Hydrochloride delivery within 3-5 business days via our Xpress Post.
The information provided above about Naltrexone Hydrochloride is for general educational purposes only. The content on this page is not intended to replace any kind of professional advice, diagnosis, or treatment. Naltrexone Hydrochloride is a prescription-only medicine and should be used strictly under the guidance of a licensed healthcare professional. Do not start, stop, or change the dosage of this medication without consulting your doctor. Reliance on this information is solely at your own risk.
If you are looking for a more affordable option, some patients choose to order prescription medications from licensed Canadian pharmacies, such as Polar Bear Meds, with a valid prescription. Canadian pharmacies may offer lower prices while still requiring proper medical authorization.
Learn more about Naltrexone Hydrochloride and related topics

We offer competitive pricing on all our medications. We'll match if you find a lower price on an identical product at a verified Canadian online pharmacy!
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