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Nextstellis

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Product Details

Description

Buy Nextstellis Online from Licensed Canadian Pharmacies

Nextstellis (drospirenone/estetrol) is a combined oral contraceptive used to prevent pregnancy in women of reproductive age. Each tablet includes 3 mg of drospirenone and 15 mg of estetrol, a distinctive estrogen that mimics the natural hormone produced during pregnancy. This combination works by preventing ovulation, increasing cervical mucus thickness, and changing the uterine lining to lower the chance of fertilization.

This medication is taken one time daily, for 28 days: 24 active tablets followed by 4 inactive ones. Nextstellis may cause side effects such as mood changes, nausea, breast tenderness, or irregular bleeding. It is not suitable for smokers over 35 or individuals with certain cardiovascular or liver conditions. To order Nextstellis online, you will need a valid prescription that you can receive from your healthcare provider.

Generic NameDrospirenone/Estetrol
Brand NameNextstellis
FormsTablet
Strengths Available15 mg/3 mg
Packaging28 tablets per pack
Requires PrescriptionPrescription only (Rx)
Ships to the USAYes
Uses and Benefits
  • Nextstellis is for females to prevent pregnancy.

Benefits of Nextstellis

  • Helps regulate menstrual cycles and reduce heavy or painful periods.
  • It may help clear acne by lowering certain hormone levels that trigger breakouts.
  • Helps lower the risk of ovarian cysts by stopping ovulation.
  • Offers protection against certain types of ovarian and endometrial cancers.
  • Improves skin quality by balancing hormones.
  • It can help ease symptoms of PMS (premenstrual syndrome) such as mood swings and cramps.
  • Generally well-tolerated due to its unique estrogen (estetrol), which offers targeted action with fewer hormonal side effects
  • May offer relief from symptoms related to hormonal imbalance, like irregular bleeding.
Dosage

Dosage of Nextstellis for Preventing Pregnancy in Women

  • Each pack contains 28 tablets:
    • 24 pink tablets (active, contain hormones)
    • 4 white tablets (inactive, no hormones)
  • Take one tablet daily in order, from left to right, without skipping any doses.
  • After finishing all 28 tablets, start a new pack the next day, even if you are still bleeding.
Usage Guide

Consider these instructions to properly take this medication when you buy Nextstellis from Canada:

  • Take one tablet daily at the same time, with or without food.
  • Start the first pack on the first day of your menstrual period or as directed by your doctor.
  • Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
  • If you experience diarrhea or vomiting within 3 to 4 hours of taking a Nextstellis tablet, take another tablet as soon as possible.
  • Use backup contraception (like condoms) for 7 days if starting for the first time or after missing pills, as directed.
  • When switching from another contraceptive, start Nextstellis on the day you would have started your next pack with your previous method.
  • Do not stop or skip tablets without consulting your healthcare provider.
How It Works

Nextstellis contains two active ingredients: drospirenone, a progestin, and estetrol (E4), a unique, plant-derived estrogen. Together, these hormones work to prevent ovulation, meaning they stop the ovary from releasing an egg. They thicken cervical mucus, creating a barrier that blocks sperm, and thin the uterine lining, reducing the chance of implantation. This combination provides effective contraception while offering potentially improved safety and tolerability.

Side Effects

Common Nextstellis side effects may include:

  • Headache
  • Acne
  • Breast pain, swelling, or tenderness
  • Irregular periods or spotting
  • Painful periods (cramps)
  • Mood changes (irritability, anxiety)
  • Low libido
  • Weight gain

Serious side effects (rare:

  • Migraine episodes
  • High potassium levels (hyperkalemia)
  • Elevated liver enzymes
  • High blood pressure
  • Depression
  • Severe allergic reactions
  • Cardiovascular events

Note: Contact your gynecologist if you experience any serious symptoms or unusual changes.

Warnings
  • Do not use Nextstellis if you are pregnant or suspect you may be pregnant.
  • Avoid if you have a history of blood clots, stroke, or certain heart conditions.
  • Not recommended for individuals with liver disease, liver tumors, or a history of hormone-sensitive cancers.
  • Use caution if you have high blood pressure, diabetes, or a history of depression.
  • This medication does not protect against HIV/AIDS or other sexually transmitted infections (STIs).
  • It can increase potassium levels; caution is required if taking potassium-raising medicines.
  • May cause gallbladder issues, report persistent abdominal pain or jaundice.
  • Stop using Nextstellis and seek medical help if you experience symptoms like shortness of breath, vision changes, chest pain, or leg swelling.
Safety Guide
  • Avoid if allergic to drospirenone, estetrol, or any ingredients in the Nextstellis tablet.
  • Can raise blood pressure; monitor regularly.
  • Avoid smoking, especially if you're over 35, due to an increased risk of serious cardiovascular side effects.
  • Stop use if new or worsening migraines (especially with aura) occur.
  • Periods may become irregular or lighter, which is normal.
  • Do not skip doses, as this can reduce effectiveness and increase the risk of pregnancy.
  • Spotting or light bleeding may occur in the first few months. Contact your doctor if it persists.
  • Inform your doctor or gynecologist about all medications and supplements you're taking.
  • Do not share this medication with others, even if they have the same condition. It may be harmful.
Missed Dose

If you miss one pink Nextstellis tablet, take it as soon as you remember, then take the next tablet at your usual time. If you miss two or more pink tablets, take only the most recent missed tablet right away and skip the others. For white tablets, simply skip the missed ones and continue as usual; no extra protection is needed.

Overdose

Taking too much Nextstellis may lead to symptoms such as nausea, vomiting, or vaginal bleeding. If an overdose is suspected, contact your gynecologist or call your local poison control center right away. For severe symptoms, seek emergency medical attention or go to the nearest hospital immediately.

Storage Guide

Follow these storage guidelines when you order Nextstellis from Canada:

  • Store at room temperature, ideally between 15°C-30°C (59°F-86°F).
  • Keep these tablets in the original pack until use. This protects them from moisture and light.
  • Avoid exposing this medication to extreme temperatures.
  • Store Nextstellis 15 mg/3 mg out of reach of children and pets.
  • Do not use the tablets past the expiration date printed on the pack.
  • Dispose of unused tablets properly; ask your pharmacist for eco-friendly disposal options.
Interactions

Nextstellis may interact with the following medications:

  • Adderall (amphetamine/dextroamphetamine)
  • Lexapro (escitalopram)
  • Pristiq (desvenlafaxine)
  • Metformin (metformin)
  • Zyrtec (cetirizine)
  • Omeprazole / Somac (omeprazole/pantoprazole).
  • Fish Oil (omega-3 fatty acids)
  • Cholestyramine (cholestyramine)
  • Locholest / Prevalite (cholestyramine)
Alternatives

If Nextstellis isn’t suitable, you may consider these alternatives under your doctor’s supervision:

  • Yaz (drospirenone/ethinyl estradiol)
  • Lo Loestrin Fe (norethindrone/ethinyl estradiol)
  • Sprintec (norgestimate/ethinyl estradiol)
  • Gianvi (drospirenone/ethinyl estradiol)
  • Beyaz (drospirenone/ethinyl estradiol/levomefolate)
  • Mirena (levonorgestrel)
  • Nexplanon (etonogestrel)
  • NuvaRing (etonogestrel/ethinyl estradiol)
  • Depo-Provera (medroxyprogesterone)
Cost & Coupons

Why Buy Nextstellis from Polar Bear Meds?

At Polar Bear Meds, we’re committed to making prescription medications like Nextstellis more accessible and affordable for USA patients. Our prices are significantly lower than typical USA pharmacy retail rates without compromising on safety or quality. Every order is sourced exclusively from licensed and trusted pharmacies and undergoes complete prescription verification to ensure compliance and authenticity. We offer discreet, trackable shipping to all USA states, along with refill support for ongoing treatment. Our friendly customer service team is here to help you.

Cost & Coupons

Get Nextstellis delivered straight from Canada to your doorstep in the USA. You can also save more by using the coupon code “WELCOMEPB10” for 10% off on your first order. There are no hidden handling or processing fees, as we believe in complete transparency. Looking to save even more? Join our referral program to earn a $20 credit every time you refer a friend or a family member. Your referral will also receive a $20 credit, so everyone wins. Additionally, after every 10 verified customer referrals, you'll receive a $100 credit in your account as a thank-you for spreading the word.

FAQ

Guarantee

AtPolar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently buy Nextstellis from Canada at a substantial cost, call us at 1-888-779-2193 toll-free.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn
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We offer competitive pricing on all our medications. We'll match if you find a lower price on an identical product at a verified Canadian online pharmacy!

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