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Hyaluronan
Orthovisc Syringe
Orthovisc Syringe is an FDA-approved treatment for osteoarthritis, containing Hyaluronan, a natural joint fluid component. It is administered via intra-articular injection into the knee. It helps alleviate pain and improve mobility in patients who are nonresponsive to conservative nonpharmacologic therapy or analgesics. Hyaluronan restores synovial fluid’s lubricating properties, easing joint friction. It is available in prefilled syringes with a concentration of 15 mg/ml, which ensures easy administration. Side effects may include provisional pain, bump, or redness at the injection site, with rare allergic reactions. Avoid it if you are allergic to Hyaluronan or its components or if there’s a skin infection at the injection site. Pregnant or breastfeeding women should seek medical consultation. You can consult your healthcare professional for essential advice or concerns.
Product Overview
Orthovisc Syringe is a prescription medical product that the FDA approves for the treatment of osteoarthritis. Its active ingredient, Hyaluronan, is a natural substance found in the synovial fluid of joints. This viscosupplement is designed explicitly for intra-articular injection into the knee joint to lessen pain and enhance joint mobility in patients who have not responded to conservative nonpharmacologic therapy or simple analgesics.
Hyaluronan functions by restoring the lubricating and cushioning properties of the synovial fluid, thereby reducing friction and easing joint movement. Orthovisc Syringe is available in prefilled syringes, facilitating easy administration by healthcare professionals.
It is commonly available in a specific formulation of 15 mg/ml of Hyaluronan in the solution prescribed by the healthcare provider. Common side effects of Orthovisc Syringes include provisional pain, bump, or redness at the injection site. In rare cases, allergic reactions may occur. If you have a known allergy to Hyaluronan or its components, you should avoid Orthovisc 15 mg ml syringe.
In case of a skin infection or disease at the injection site, you should not receive Orthovisc injections. Healthcare providers should be consulted before using the medicine in pregnant or breastfeeding women, as safety data in these populations may be limited. A healthcare professional should promptly address any concerns.
Uses of Orthovisc Syringe
- It is used to treat knee pain in those with osteoarthritis.
How to Use Orthovisc Syringe?
Form: Prefilled syringe
Strength: 15 mg/ml of Hyaluronan
Here are the steps for proper administration of Orthovisc Syringe:
Step 1. Gather the necessary supplies, including an Orthovisc syringe, alcohol wipes, and gloves, and ensure a clean, well-lit area for the procedure.
Step 2. Position the patient comfortably, typically lying down or sitting with their knee exposed.
Step 3. Clean the injection site (typically the knee) with an alcohol wipe to minimize the risk of infection.
Step 4. If there is excess fluid in the knee joint, your healthcare provider may perform an aspiration to remove it before injecting Orthovisc. This step is only sometimes necessary.
Step 5. Remove the cap from the Orthovisc syringe. Ensure that the syringe is intact and not damaged.
Step 6. The healthcare provider will identify the appropriate injection site and insert the needle into the knee joint. They will slowly depress the plunger to inject the Orthovisc solution.
Step 7. After injecting the solution, the healthcare provider will carefully withdraw the needle.
Step 8. Apply pressure to the site of injection with a sterile gauze pad to help reduce any bleeding. Dispose of the used syringe and other medical waste properly.
[Note: Your healthcare professional will determine the correct dosage of Orthovisc for you based on your medical condition. They’ll adjust the dosage as needed over time.]
How Does Orthovisc Syringe Work?
Orthovisc contains Hyaluronan, a substance naturally found in healthy joint fluid, which acts as a lubricant and shock absorber in the knee joint. When injected into the knee affected by osteoarthritis, Orthovisc supplements the diminished hyaluronic acid, improving joint lubrication and cushioning. This helps decrease friction between the bones and alleviates pain and stiffness associated with osteoarthritis. Orthovisc may also have anti-inflammatory effects, further contributing to pain relief.
Important Safety Information
Side Effects
Common side effects of Orthovisc Syringe:
- Injection site reactions (redness, swelling, pain, bruising)
- Joint stiffness
- Bleeding or bruising at the injection site
- Headache or dizziness
Severe side effects of Orthovisc Syringe:
- Allergic reactions (itching, rash, hives)
- Infection (pain, swelling, warmth, redness)
- Nerve damage (numbness, tingling)
Precautions
- Ensure that the packaging is intact and the expiration date has not passed.
- Wash your hands thoroughly with soap and water before handling the syringe to prevent contamination.
- Inspect the syringe visually for any signs of damage or defects before use.
- Read the leaflet provided by your healthcare professional before starting treatment and with each refill.
- If there’s excess fluid in the joint, it may need to be removed before the injection.
- After the injection, avoid activities that stress your knee (e.g., jogging, tennis, heavy lifting) for 48 hours.
- You may experience increased pain and swelling initially. If these symptoms last or worsen, call your doctor promptly.
- Do not reuse the syringe or any of its components to prevent cross-contamination and potential adverse reactions.
- Dispose of the Orthovisc 15 mg ml syringe and any unused medication properly according to local regulations after use.
Storage
- Store the Orthovisc syringe at room temperature, away from direct sunlight and heat sources.
- Keep the syringe in its original box until ready for use to protect it from contamination.
- Avoid freezing the syringe, as this can damage the medication.
- Keep the syringe out of reach of children and pets to prevent accidental exposure.
- Do not store the syringe in extreme temperatures or humid environments, as this may affect its stability.
[Note: Discuss with your healthcare professional about the proper storage and disposal technique of any unused Orthovisc syringe.]
Frequently Asked Questions
How long does it take for Orthovisc to work?
Orthovisc typically provides relief within four to twelve weeks. The effects can last for several months, making it a valuable option for managing discomfort. If you receive multiple injections, they are usually spaced at least one week apart. Remember to follow your doctor’s dosing instructions carefully and monitor your symptoms.
Can I exercise after injecting the Orthovisc Syringe?
Yes, after receiving an Orthovisc Syringe injection, you can do mild exercises like walking. You should not do high-impact exercises (such as running or heavy weightlifting) for at least 48 hours. Gradually reintroduce exercise and monitor how your knee responds. Always follow your doctor’s advice to ensure a safe and effective recovery.
How often can I receive injections of Orthovisc Syringe?
The frequency of Orthovisc Syringe injections depends on your specific condition and your doctor’s recommendation. Typically, injections are spaced at least one week apart. Your healthcare professional will assess your response and determine the most suitable schedule for your treatment. Always follow their guidance to ensure optimal results and safety.
What precautions should I take after injecting Orthovisc?
After injecting Orthovisc, consider these precautions:
- Rest the injected joint for a short period.
- Avoid strenuous activities for a day or two.
- Apply ice to the injected area if there’s swelling or discomfort.
- Follow up with your healthcare provider for any concerns or adverse reactions.
- Stick to the guidelines given by your healthcare provider.
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