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Pimecrolimus Cream

Pimecrolimus is a medicine approved by the FDA to treat mild to moderate eczema in people who tried other medications that didn’t work well. Pimecrolimus, available in a 1% strength & part of a group called topical calcineurin inhibitors, helps suppress the symptoms of eczema, like itching, redness, or skin inflammation caused by the body’s immune system. So, if you want to buy Pimecrolimus cream online from a Canadian Pharmacy, which comes in 30, 60, or 100-gram tubes, you must have a prescription from your doctor.

Product Overview

Pimecrolimus is an FDA-approved cream designed to prevent mild to moderate eczema. It falls under the category of topical calcineurin inhibitors, which aid in alleviating eczema symptoms such as itching and redness caused by the immune system. Pimecrolimus achieves this by slowing down the immune system’s response, specifically targeting skin cells without impacting the overall immune system. The cream is available in 30, 60, or 100-gram tubes, each with recommended dosages for various skin conditions. 

To apply, a thin layer should be used twice daily on affected skin areas while avoiding application on areas at risk of skin cancer. Washing hands before and after use is essential, and covered skin should only be as per the provided instructions. As with many medications, Pimecrolimus does have side effects, with common ones including stinging and body aches, and more severe effects potentially including intense itching or changes in mole color. Despite its effectiveness, cautionary measures can be taken while using Pimecrolimus cream, such as refraining from use in case of allergies, disclosing medical history, and discussing the risk of cancer with a doctor. 

Breastfeeding or Pregnant individuals should consult a doctor before use. In case of a missed dose, the application should occur as soon as it is remembered without exceeding the recommended amount. Pimecrolimus, effective when used as prescribed, is unavailable over the counter and can be cautiously applied to a child’s face. Consultation with a doctor is recommended for individuals with diabetes or those needing to apply the cream to sensitive areas like the groin.

Uses of Pimecrolimus Cream

  • Used to treat mild to moderate eczema-like redness, skin inflammation, or itching.

How to Use Pimecrolimus Cream?


Pimecrolimus Cream can be taken topically. It is available in 1% strength and different tubes as follows:

  • 30 grams
  • 60 grams
  • 100 grams

Recommended Dosage for Different Patients

Atopic Dermatitis

  • For adults, teenagers, and children aged 2 and older, apply a thin layer of Pimecrolimus Cream (1%)  to the affected skin areas twice daily. It is not recommended for children under 2 years of age.

Oral Lichen Planus (Off-label use)

  • Apply 2 times daily for 1 month.

[Note: Remember these recommendations may vary depending on person to person. Discuss it with your doctor, and they’ll customize your Pimecrolimus cream amount accordingly.]

How to Take It?

  • Don’t swallow this medicine; use it only on your skin.
  • Wash your hands before and after putting on the Pimecrolimus cream unless you’re treating eczema on your hands. If you’re applying it to someone else, wash your hands afterwards.
  • Apply a thin layer of the Pimecrolimus cream on clean, dry skin and gently rub it in. Use the smallest amount needed to control eczema symptoms.
  • Only use the medicine on the skin affected by eczema and avoid applying it to areas possibly affected by skin cancer.
  • After applying, you should use a moisturizing cream or lotion to protect your skin from getting too dry. Consult your doctor about the appropriate product.
  • Don’t cover the treated skin with a bandage unless your doctor instructs you to do so.
  • Avoid bathing, showering, or swimming right after applying the cream, as water may wash off the medicine.

[Note: Your healthcare professional or doctor will decide the accurate Pimecrolimus cream amount for you based on following guidelines, your specific condition, and studies on this medication.]

How Does Pimecrolimus Cream Work?

Pimecrolimus cream operates by slowing down the activity of calcineurin, a crucial enzyme in the immune system’s response. By inhibiting calcineurin, Pimecrolimus cream aids in lessening inflammation and itching related to skin conditions such as eczema. This medication focuses on the immune cells in the skin without impacting the overall immune system, offering a precise and efficient treatment for inflammatory skin disorders.

Important Safety Information

Side Effects

Common side effects of Pimecrolimus cream (1%) include:

  • Stinging, Burning, or Soreness of Treated Skin
  • Body Aches
  • Sore Throat
  • Viral Skin Infection
  • Headache
  • Runny or Stuffy Nose
  • Chills
  • Fever
  • Cough
  • Swollen Glands

Serious side effects of Pimecrolimus cream (1%) include:

  • Severe Itching
  • Warts
  • Unusual Rash or Skin Lesions
  • Changed Moles Color

[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]


Allergic Reactions: If you are allergic to Pimecrolimus, refrain from using it.

Medical History: Inform your doctor if you have had:

  • Skin cancer
  • Netherton’s syndrome 
  • Bacterial or viral skin infections 
  • Weak immune system 

Cancer Risk: Some Pimecrolimus or tacrolimus skin medication users have reported skin cancer or lymphoma cases. While it’s uncertain if these medications directly cause cancer, it’s crucial to discuss your risk with your doctor.


Unknown Impact on Unborn Baby: The potential harm to an unborn baby from using Pimecrolimus topical is not established. Inform your healthcare provider or doctor if you are pregnant or planning to become pregnant.

Breastfeeding: It is recommended not to breastfeed while using Pimecrolimus.

Missed Dose

  • If you missed applying Pimecrolimus cream, apply the medicine as soon as you remember.
  • You can skip the application of Pimecrolimus cream if it is almost time for your next application.
  • Only use as much as the doctor recommended.

[Note: If you have missed your medication application and are unsure when to apply it the next time, immediately consult your doctor or pharmacist.]


Applying more than the recommended amounts of this medication can cause severe itching and may lead to skin burns. Seek medical attention immediately if you have serious rashes and itching in your body.

[Note: If you applied more than the recommended amount, get medical help right away or call the Poison Help line at 1-800-222-1222.]


  • Keep the cream in a closed container to stop dirt from getting in.
  • Store the medicine where it’s not too hot or too cold, just like in a normal room (between 68°F to 77°F or 20°C to 25°C).
  • Don’t put the cream in the freezer because very cold or hot places can change how it works.
  • Put it in a place where it won’t get direct light. Direct exposure to sunlight can destroy its effectiveness.
  • Keep the cream in a cool, dry spot to make sure it stays the way it should.
  • Make sure to keep it away from children and pets.
  • If you have any leftovers or old cream, ask your healthcare person how to throw it away safely.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Pimecrolimus Cream Interactions

  • Fluconazole 
  • Itraconazole 
  • Ketoconazole
  • Diltiazem 
  • Verapamil
  • Cimetidine
  • Clarithromycin 
  • Erythromycin 
  • Troleandomycin 
  • Metronidazole
  • Cyclosporine
  • Indinavir 
  • Ritonavir
  • Delavirdine
  • Nefazodone 
  • Fluoxetine
  • Fluvoxamine

[Note: This isn’t a complete list and other medications could interact with Pimecrolimus cream. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Pimecrolimus Cream Alternatives

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Frequently Asked Questions

Is Pimecrolimus effective?

Yes! Pimecrolimus can be proven to be efficacious when applied according to the prescribed dosage and duration recommended by your healthcare professional. It is crucial to continue its use, even if there is apparent improvement in your condition. If you stop Pimecrolimus, then that may lead to the recurrence or exacerbation of symptoms.

Is Pimecrolimus available over the counter?

No! Pimecrolimus is not available as an over-the-counter medication; it is strictly a prescription medicine. This implies that individuals can acquire Pimecrolimus only by presenting a valid prescription issued by a qualified healthcare professional. Additionally, it’s crucial to consult with a doctor before obtaining and using this medication to ensure its appropriateness for the specific medical condition at hand.

Can I use Pimecrolimus Cream on my child’s face?

Yes, you can use Pimecrolimus cream on your child’s face, but it’s important to listen to your doctor. Only apply a small amount of the cream to the places your doctor tells you. Be careful around the eyes and mouth. Use the exact amount your doctor suggests. If you’re worried or see any irritation, talk to your healthcare provider or doctor for advice on using Pimecrolimus safely on your child’s face.

Can I use Pimecrolimus cream 1% if I have diabetes?

If you are suffering from higher sugar levels or diabetes, talk to your healthcare provider or doctor before using Pimecrolimus. It’s important to discuss how it may affect your blood sugar levels. Your doctor can help you manage diabetes while using this medication. Be sure to follow their advice on the proper application and any adjustments needed to keep your diabetes under control during Pimecrolimus treatment.

Is it safe to use Pimecrolimus on sensitive areas like the groin?

Yes, you can use Pimecrolimus on sensitive areas like the groin. Apply a thin layer as directed, avoiding contact with mucous membranes. Be cautious, and don’t use more than prescribed. If you have concerns or experience irritation, consult your healthcare provider for guidance on using Pimecrolimus safely on sensitive skin areas.

Our Guarantee

At, we assure you the most affordable price to buy Pimecrolimus cream from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently access Pimecrolimus Cream at a substantial cost, call us at 1-888-779-2193 toll-free.


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