Propranolol Hydrochloride

Propranolol Hydrochloride is FDA-approved for treating conditions such as hypertension, migraines, essential tremors, angina, atrial fibrillation, myocardial infarction, hypertrophic subaortic stenosis and pheochromocytoma. It is available in the form of injections, oral solutions and tablets. The tablets are available in different strengths: 10 mg, 20 mg, 40 mg and 80 mg. Do not use it if you are suffering from cardiogenic shock, bronchial asthma, sinus bradycardia and congestive heart failure. For guidance on usage, dosage, potential risks, and benefits, consult your doctor and use the medication as prescribed.

Propranolol Hydrochloride is a medication containing Propranolol, a beta-blocker that slows down the heart rate and eases the heart’s workload, making it a vital treatment for conditions such as hypertension, migraines, essential tremors, angina, and more. It achieves this by blocking the nerve impulses responsible for increased heart activity, thereby stabilizing blood pressure and preventing heart attacks.

Available in tablet form, Propranolol Hydrochloride comes in strengths of 10 mg, 20 mg, 40 mg, and 80 mg. The recommended dosage varies depending on the condition being treated, and it’s essential to follow your doctor’s instructions for use. Patients with conditions such as cardiogenic shock, bronchial asthma, sinus bradycardia, and congestive heart failure should avoid using this medication.

Common side effects include slow heart rate, fatigue, nausea, and insomnia, while more severe reactions can include allergic reactions and heart problems. Patients should exercise caution when using this medication, especially those with a history of heart conditions or diabetes. In case of a missed dose, take it as soon as possible unless it’s almost time for the next dose. For overdoses, seek immediate medical attention. Store the medication at room temperature, away from direct sunlight and moisture, and keep it out of reach of children and pets. Always consult your healthcare provider for guidance on usage, dosage, and any potential interactions with other medications.

This medication is used to:

• Treat angina, hypertension, essential tremors irr, irregular heartbeats or other heart or circulatory conditions.
• Preventing a heart attack.
• Increase the chance of survival after heart failure.
• Reduce the frequency and severity of migraines.

Propranolol chloride comes in the form of oral solution and tablets. The tablet comes in different strengths:

• 10 mg
• 20 mg
• 40 mg
• 80 mg

Recommended Dosage for Different Patients

Recommended Dosage for Hypertension:

The recommended starting dose of Propranolol Hydrochloride for treating hypertension is usually 40 mg twice every day and increased up to a maximum dose of 640 mg daily in different doses.

Recommended Dosage for Angina Pectoris:

The usual starting dose of Propranolol Hydrochloride for Angina Pectoris is 40 mg twice every day, which is gradually increased up to 320 mg per day depending on the patient’s response.

Recommended Dosage for Arrhythmias:

The initial doses of Propranolol Hydrochloride for arrhythmias typically range from 10 mg to 30 mg three to four times daily.

Recommended Dosage for Migraine Prophylaxis:

The initial dose of Propranolol Hydrochloride for migraine is 80 mg daily in different doses. The dosage may be increased gradually up to 240 mg per day based on the patient’s response.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

• It is essential to take Propranolol Hydrochloride Tablets as instructed by your doctor.
• Do not take it in more frequency or for longer than needed.
• Read the instructions for use carefully before starting to take the medicine.
• Ask your doctor/ healthcare provider if you have any queries or concerns.
• You should swallow the tablet as a whole.
• Do not crush, chew or break the tablets.
• It is usually to be taken at bedtime with or without food.
• To get the best results and to maintain consistency, it is recommended to take it at the same time every day.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

Propranolol Hydrochloride works by blocking the beta receptors found in the heart and blood vessels. It inhibits the action of epinephrine and norepinephrine, which are produced by the brain and further reduces strain on the heart and blood pressure. It also can reduce the severity and frequency of migraine headaches and angina. It makes it easier for the heart to pump blood around the body by slowing down the heart rate, thus making you feel less anxious.

Common side effects of Propranolol Hydrochloride Tablets may include:

• Slow heart rate
• Nightmares
• Cold extremities
• Fatigue
• Nausea or vomiting
• Constipation
• Diarrhea
• Insomnia
• Sore throat
• Mood disorders
• Weight gain
• Sexual dysfunction

Severe side effects of Propranolol Hydrochloride Tablets may include:

• Severe allergic reactions
• Severe skin reactions
• Trouble breathing
• Heart problems
• Hypoglycemia

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

• You should not use Propranolol Hydrochloride if you have languid heartbeats, asthma, heart failure, sick sinus syndrome or AV block.
• You should not abruptly stop taking this medicine as it may result in chest pain or a heart attack.
• Do not take this medication if you have an allergy to Propranolol Hydrochloride or any of its inactive ingredients.
• If you are planning to have surgery, including dental surgery, tell your doctor that you are taking propranolol hydrochloride.
• Suppose you have diabetes, or you are fasting or not eating food regularly. In that case, you might be having difficulty managing your blood sugar levels and also at an increased risk of hypoglycemia.

Boxed Warning

Propranolol Hydrochloride has a black box warning stating that you should not suddenly stop taking the medication without consulting your doctor. Abruptly stopping the drug may result in heart failure. You should restart taking Propranolol if you start experiencing chest pain. Suppose you need to stop taking the medicine. In that case, your healthcare provider will help you by decreasing the dosage gradually and temporarily limiting your physical activity to avoid putting strain on your heart.

• You should avoid consuming alcohol while on treatment with Propranolol Hydrochloride, as it may increase or decrease your blood sugar levels.
• Suppose you are pregnant, planning to get pregnant or are breastfeeding a baby. In that case, it is essential to consult your doctor or healthcare provider and discuss the potential risks and benefits of the medicine.
• Before you start using your medication, let your doctor know about your medical history, medical conditions you may have and the medications you are using to treat the condition.

Propranolol Hydrochloride is contraindicated for use in patients with:

• Cardiogenic shock
• Bronchial asthma
• Sinus bradycardia
• Congestive heart failure

• If you have missed a dose of Propranolol Hydrochloride, take it as soon as you realize you have missed your medication.
• But if it is almost time for your next dose, you may skip your missed dose and take the next dose as per your dosing schedule.
• Do not take two doses of the same medicine at the same time to compensate for the missed dose.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

Symptoms of an overdose may include feeling light-headedness, rapid or slow heartbeats, tremors, and trouble breathing. If you are facing any of these symptoms, seek immediate medical assistance. You may call 911 or head to the nearest emergency room.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

• Store Propranolol Hydrochloride in a closed container at room temperature, away from direct sunlight and excess heat.
• Do not freeze the medicine; do not use it if it is frozen. Using frozen insulin can be painful.
• Throw away expired or no longer-needed medication safely.
• Do not use Propranolol after 2 months of opening the bottle.
• Keep the medicine away from children and pets.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

• Cholestyramine or colestipol
• Antidepressants
• Antidiabetics
• Medicines used to treat heart conditions and blood pressure
• Steroid medicine
• NSAIDs like aspirin, ibuprofen, diclofenac, meloxicam and more.
• Alpha-blockers

[Note: This isn’t the complete list, and there could be other drugs that interact with Propranolol Hydrochloride. Tell your doctor about any over-the-counter medicines, prescription, and herbal products you’re taking.]

• Aimovig (erenumab)
• Emgality (galcanezumab)
• Tenormin (atenolol)
• metoprolol succinate
• Bystolic (nebivolol)
• Zestril (lisinopril)
• Coreg (carvedilol)
• Diovan (valsartan)
• Cardizem CD (diltiazem extended-release)
• Norvasc (amlodipine)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

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