Seasonique

Seasonique is a prescription extended-cycle combination oral contraceptive that contains levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). It is designed to prevent pregnancy using a 91-day dosing regimen. Seasonique provides 84 days of active hormone tablets followed by 7 days of low-dose estrogen tablets, resulting in fewer scheduled menstrual periods (about four per year).

Seasonique is indicated for:

• Prevention of pregnancy in women who choose to use oral contraception.

Do not take Seasonique if you have any of the following conditions:

• Cigarette smoking if you are over 35 years of age (increased risk of serious cardiovascular events)
• A high risk of venous thrombotic or arterial diseases, including a history of deep vein thrombosis (DVT) or pulmonary embolism
• Breast cancer or other estrogen/progestin-sensitive cancers
• Undiagnosed abnormal uterine bleeding
• Liver tumors or severe liver disease, including acute viral hepatitis or decompensated cirrhosis
• Concomitant use of certain hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir
• Known hypersensitivity to any component of Seasonique

Cardiovascular and Thromboembolic Risk

• Combination hormonal contraceptives, including Seasonique, are associated with an increased risk of venous thrombotic and arterial events such as myocardial infarction, DVT, stroke, and pulmonary embolism.
• The risk is greater in women who are older and in those with additional cardiovascular risk factors (e.g., smoking, hypertension, diabetes).

Vascular Events and Surgery

• Discontinue Seasonique at least 4 weeks before major surgery and do not restart until at least 2 weeks after to reduce thromboembolism risk.

Liver Disease and Liver Tumors

• Discontinue Seasonique if jaundice develops or if liver test abnormalities occur.
• Seasonique is contraindicated in patients with liver tumors, and acute liver disease should prompt discontinuation.

Hypertension

• Monitor blood pressure in all women taking Seasonique, especially those with controlled hypertension, and stop if BP rises significantly.

Metabolic Effects

• May cause adverse glucose tolerance and lipid changes; monitor in women with pre-diabetic conditions.

Headache and Migraine

• Severe or persistent headaches, especially with focal neurological symptoms or migraine with aura, may increase the risk of cerebrovascular events.

Other Important Considerations

• Gallbladder disease may be worsened by Seasonique use.
• Monitor women for depression; discontinue if serious depression recurs.
• Chloasma (pigmentation changes) may occur; advise sun exposure protection.

Seasonique may cause side effects that range from mild to serious due to its combination of estrogen and progestin hormones. This is not a complete list of possible Seasonique side effects. If you experience serious or unexpected side effects, contact your healthcare provider immediately. You can report Seasonique side effects to the FDA’s MedWatch program at 1-800-FDA-1088 or www.fda.gov/medwatch.

If you are using Seasonique for pregnancy prevention, make sure to follow these administration steps:

• Take one tablet by mouth at the same time every day in the order directed on the blister pack.
• Tablets may be taken with or without food.
• Swallow the tablet whole with water.
• Do not skip doses. Missing pills increases the risk of pregnancy.
• If vomiting or severe diarrhea occurs within 3–4 hours after taking a tablet, follow the missed-pill instructions provided in the patient labeling.
• Use a non-hormonal backup method of contraception during the first 7 days when starting Seasonique if instructed.
• Do not stop taking Seasonique without consulting your healthcare provider.

Seasonique 0.15 mg-0.03 mg/0.01 mg is a combined oral contraceptive containing ethinyl estradiol (an estrogen) and levonorgestrel (a progestin). It prevents pregnancy through multiple, FDA-established mechanisms:

1. Inhibits Ovulation: The hormones suppress the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), preventing the ovary from releasing an egg.
2. Thickens Cervical Mucus: Levonorgestrel increases the thickness of cervical mucus, making it more difficult for sperm to reach and fertilize an egg.
3. Alters the Endometrium: The uterine lining becomes less suitable for implantation if fertilization were to occur.

The following dosing information for Seasonique is based on the FDA prescribing information for pregnancy prevention:

Seasonique Dosage Phases

Always follow your healthcare provider’s instructions when starting Seasonique, stopping it, or making any changes to your dose. Do not begin, discontinue, or adjust this medication without medical guidance.

If you miss one active tablet (Days 1–84):

• Take the missed Seasonique tablet as soon as you remember.
• Take the next one at your regular time (this may mean taking two tablets in one day).
• No backup contraception is needed if only one tablet is missed.

If you miss two consecutive active tablets (Days 1–84):

• Take two tablets on the day you remember and two tablets the next day.
• Then continue taking one tablet daily as scheduled.
• Use non-hormonal backup contraception (such as condoms) for 7 days.

If you miss three or more consecutive active tablets (Days 1–84):

• Do not take the missed tablets.
• Continue taking one tablet daily at the usual time.
• Use non-hormonal backup contraception for 7 days.
• If missed tablets occur early in the pack, pregnancy risk may be higher.

If you miss one of the 7 low-dose estrogen tablets (Days 85–91):

• Discard the missed tablet and continue taking one tablet daily until the pack is finished.
• Backup contraception is not required.

Important Information:

• Missing Seasonique tablets increases the risk of pregnancy.
• If you miss pills and do not have a scheduled withdrawal bleed, consider pregnancy testing.
• Refer to the patient labeling for complete missed-pill instructions.

Seasonique may interact with certain medications that affect hormone metabolism or increase the risk of adverse events. Always inform your provider about all prescription drugs, OTC medicines, and supplements you are taking.

If Seasonique is not suitable, other FDA-approved hormonal contraceptives are available for pregnancy prevention. Below are some Seasonique alternatives you can consider under medical supervision:

Combined Oral Contraceptives (COCs)

• Seasonale (levonorgestrel/ethinyl estradiol)
• Amethia (levonorgestrel/ethinyl estradiol)
• LoSeasonique (levonorgestrel/ethinyl estradiol)
• Yaz (drospirenone/ethinyl estradiol)
• Ortho Tri-Cyclen (norgestimate/ethinyl estradiol)

Progestin-Only Pills (POPs)

• Camila (norethindrone)
• Micronor (norethindrone)

Long-Acting Reversible Contraceptives (LARCs)

• Mirena (levonorgestrel intrauterine system)
• Kyleena (levonorgestrel intrauterine system)
• Nexplanon (etonogestrel implant)

Other Hormonal Methods

• Depo-Provera (medroxyprogesterone acetate injection)
• NuvaRing (etonogestrel/ethinyl estradiol vaginal ring)
• Xulane (norelgestromin/ethinyl estradiol transdermal patch)

At Polar Bear Meds, we help make Seasonique more affordable without compromising on quality. By partnering with licensed Canadian pharmacies, we offer Seasonique at prices often up to 80% lower than those of typical U.S. pharmacies.

New customers may save even more by using the Seasonique coupon code “WELCOMEPB10” for an extra 10% off. No insurance is required, and there are no hidden fees. All orders are shipped fast and discreetly; typically within 3–5 business days via Xpress Post, making it simple and reliable to start your treatment.

• https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/021840s012s013lbl.pdf
• https://www.drugs.com/seasonique.html
• https://www.nps.org.au/assets/medicines/7ef604f1-c3c9-495a-9c37-a6b100bf810c.pdf
• https://reference.medscape.com/drug/altavera-seasonique-levonorgestrel-oral-ethinyl-estradiol-342762
• https://www.webmd.com/drugs/levonorgestrel-ethinyl-estradiol-vienva