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Levonorgestrel and Ethinyl Estradiol

Seasonique

Seasonique is an FDA-approved contraceptive pill containing 0.15mg Levonorgestrel and 0.03mg Ethinyl Estradiol. It prevents pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the uterine lining. It’s also used to manage menstrual irregularities. Each pack has 91 tablets: 84 active (light blue-green) and 7 inactive (yellow). Take one active tablet daily for 84 days, followed by 7 inactive tablets. Side effects of Seasonique may include nausea, headache, and breakthrough bleeding. Avoid smoking while on Seasonique to prevent cardiovascular events. If you miss a dose, take it when remembered and store it at room temperature. Follow your healthcare professional guidance for effective use.

Product Overview

Seasonique is an FDA-approved oral contraceptive pill designed to prevent pregnancy. Each active tablet contains a combination of two hormones: 0.15 milligrams of Levonorgestrel, a progestin, and 0.03 milligrams of Ethinyl Estradiol, an estrogen. This formulation is used to inhibit ovulation, thicken cervical mucus to impede sperm penetration, and alter the uterine lining to deter implantation of a fertilized egg, collectively providing highly effective contraception. 

Seasonique is also prescribed to manage menstrual cycle irregularities and alleviate symptoms such as painful periods. It comes in packs of 91 tablets: 84 light blue-green active tablets containing the hormones and 7 yellow inactive tablets. To use, one active tablet is taken daily for 84 straight days, followed by 7 days of inactive tablets during which menstruation typically occurs. It’s essential to take the tablets at the same time each day. 

Seasonique is suitable for most healthy women of reproductive age, but medical history, age, and lifestyle factors should be considered before use. Common side effects of Seasonique may include nausea, headache, breast tenderness, and breakthrough bleeding. It’s advised to promptly report a severe side effect of Seasonique, like chest pain, sudden vision changes, or severe headaches. 

Precautions include avoiding smoking while taking Seasonique birth control due to increased risk of cardiovascular events. In case of a missed dose, the missed tablet should be taken as soon as remembered, and if multiple doses are missed, backup contraception may be needed. Seasonique should be stored at room temperature, away from heat, moisture, and children. You should discuss your medical history and contraindications with your healthcare provider. 

Uses of Seasonique

• It is used as a contraceptive to prevent pregnancy.

How to Use Seasonique?

Dosage

Strengths and Forms

It is available in tablet form in are available in Extended-Cycle Tablet Dispensers containing 91 tablets: 

• 84 light blue-green active tablets
• 7 yellow inactive tablets

Recommended Dosage for Seasonique

For Adult Women (Women of Reproductive Age):

• Take one light blue-green tablet daily for 84 consecutive days.
• Followed by one yellow tablet daily for 7 straight days.

Dosage Modifications

Switching from Another Contraceptive Method:

• Start Seasonique on the Sunday after the next period begins.
• Use additional non-hormonal contraception for the first 7 days.

Starting After Abortion or Miscarriage:

• For first-trimester events, begin on the Sunday after.
• Use additional non-hormonal contraception until 7 days of light blue-green tablet intake.
• For second-trimester events, wait 4 weeks before starting.

Starting After Childbirth:

• Delay Seasonique for 4 weeks post-delivery.
• Use additional non-hormonal contraception until 7 days of light blue-green tablet intake.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your Seasonique birth control dosage accordingly.]

How to Take It?

• Take one pill daily at the same time.
• Start with the first light blue-green pill on the Sunday after menstruation starts.
• Use backup contraception for the first 7 days.
• Finish one tablet dispenser.
• Start the next dispenser the day after finishing the last yellow pill.
• Do not skip tablets, even if you are noticing spotting or nausea.
• Continue taking pills daily, regardless of sexual activity frequency.

[Note: Your doctor will decide the right amount of Seasonique for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Seasonique Work?

Seasonique works by combining two hormones, Levonorgestrel, and Ethinyl Estradiol, to prevent pregnancy. These hormones inhibit ovulation, thicken cervical mucus to impede sperm penetration, and alter the uterine lining to deter implantation of a fertilized egg. By disrupting the menstrual cycle and creating an inhospitable environment for conception and implantation, Seasonique provides highly effective contraception when taken as directed.

Important Safety Information

Side Effects

Common side effects of Seasonique may include:

• Nausea
• Breast tenderness
• Vaginal bleeding between menstrual periods
• Acne
• Gastrointestinal upset

Mild side effects of Seasonique may include:

• Headache
• Heavy or irregular vaginal bleeding
• Weight changes
• Mood changes
• Anxiety or panic attacks
• Breast pain
• Migraines

Adverse side effects of Seasonique may include:

• Absent, missed, or irregular menstrual periods
• Blurred vision
• Problem in speaking
• Dizziness or lightheadedness
• Fainting
• Fluid-filled skin blisters
• Severe headache
• Pain during sexual intercourse
• Chest pain or discomfort
• Pelvic pain
• Sensitivity to the sun
• Swelling in the abdominal area
• Unusual tiredness or weakness
• Vomiting of blood
• Yellowing of eyes or skin
• Inability to move arms, legs, or facial muscles

[Note: Remember, this list may not cover all possible side effects of Seasonique. Always consult with your healthcare giver for medical advice about side effects.]

Warnings

Blood Clot Risk: Seasonique contains ethinyl estradiol, which can increase blood clot formation, particularly in those with certain risk factors such as smoking, obesity, high blood pressure, or recent surgery with prolonged bed rest. Seek your healthcare professional’s help if you notice symptoms like weakness or numbness in limbs, trouble speaking, chest pain, or difficulty breathing.

Breast and Cervical Cancer Risk: Long-term use of Seasonique may slightly increase the risk of breast and cervical cancer. Individuals with a history of these cancers should avoid Seasonique. Regular breast exams and cervical cancer screenings are recommended for those currently or recently on Seasonique.

Liver Problems: Seasonique may pose risks to individuals with liver problems, especially if taken for extended periods or alongside certain hepatitis C medications. Signs of liver issues include jaundice, fever, fatigue, and dark urine. Discontinue Seasonique and consult a healthcare provider if such symptoms occur.

Gallbladder Problems: Seasonique may raise the risk of gallbladder disease due to increased estrogen and progestin levels. Discuss any history of gallbladder issues with your healthcare provider before starting Seasonique.

High Blood Sugar and Triglycerides: Seasonique birth control may elevate blood sugar and triglyceride levels, especially in those with existing high levels. Monitor these levels closely or consider alternative birth control methods if you have a history of high blood sugar or triglycerides.

High Blood Pressure: Seasonique can increase blood pressure, particularly in older individuals or those with a history of high blood pressure or kidney problems. Regular blood pressure monitoring is essential while on Seasonique.

Headache: Inform your healthcare provider if you experience new or worsening migraines or headaches while taking Seasonique, as this may warrant discontinuation of the medication.

Irregular Bleeding: Seasonique may cause irregular bleeding or spotting, especially during the first three months of use. While usually temporary, persistent or heavy bleeding should be reported to your healthcare professional for evaluation.

Cigarette Smoking and Serious Cardiovascular Events

Seasonique carries a boxed warning regarding the increased risk of severe heart events, including blood clots, heart attacks, and strokes. This risk is highest in women who smoke and in women over the age of 35. Women with a history of blood clots, certain clotting disorders, or other risk factors for cardiovascular disease should discuss alternative contraceptive options with their healthcare provider.

Precautions

• You should follow the prescribed dosage schedule strictly.
• Take Seasonique at the same time every day to maintain effectiveness.
• Keep Seasonique at room temperature, away from moisture and heat.
• Keep track of your menstrual cycle while on Seasonique.
• Tell your healthcare professional about any existing medical conditions or medications before starting Seasonique.
• Attend regular check-ups with your healthcare professional to monitor a possible side effect of Seasonique birth control.
• If you skip a dose, follow the guidelines provided with your Seasonique medicine or consult your healthcare provider.
• Do not use Seasonique if you are pregnant or suspect you may be pregnant.
• Be cautious of the interaction of Seasonique with other medications or supplements you may be taking.
• Report any atypical symptoms or concerns to your healthcare provider promptly.

Seasonique Contraindications

• High chances of arterial or venous thrombotic diseases in women who smoke (especially if over age 35).
• Undiagnosed abnormal uterine bleeding.
• Women who currently have or have had breast cancer.
• Women with liver tumors, liver disease, acute viral hepatitis, or decompensated cirrhosis.

Missed Dose

Missing a dose of Seasonique, like any birth control pill, can potentially reduce its effectiveness in preventing pregnancy. Here’s what you need to know about missed doses:

One Missed Pill: If you miss a single active pill, take it as soon as you remember, even if it means taking two pills in one day. Then, continue taking your pills at the usual time. There’s no need for backup contraception, and the risk of pregnancy is generally low if only one pill is missed.

Two or More Missed Pills: If you miss two or more active pills in a row, the risk of pregnancy increases. In such cases:

• Take the most recently missed pill immediately, even if it means taking two pills in one day.
• Skip any missed pill(s) from earlier days.
• Continue taking the rest of the pack as scheduled.
• Use backup contraception, such as condoms, for the next seven days.
• If the missed pills occur in the third week of the pack, finish the active pills in the current pack and start a new pack immediately without taking the inactive pills. This will ensure continuous contraception and may help regulate your cycle.

Missed Inactive Pills: If you miss one or more inactive (reminder) pills, it’s not a cause for concern. Ignore the missed pills and continue taking the active pills as scheduled.

[Note: If you have missed a dose of Seasonique birth pills and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

Overdose

If you take more Seasonique birth control pills than prescribed, you may experience symptoms such as nausea, vomiting, vaginal bleeding, or breakthrough bleeding. An overdose can lead to symptoms like:

• Dizziness
• Fainting
• Severe abdominal pain
• Unusual tiredness

[Note: If you consumed more than the recommended dose of Seasonique, get medical help right away or call the Poison Help line at 1-800-222-1222.]

Storage

• Store Seasonique at room temperature, typically between 68°F and 77°F.
• Keep Seasonique in a dry place, away from moisture and humidity. Avoid storing it in wet areas, such as bathrooms.
• Do not expose Seasonique to extreme temperatures, such as freezing or excessive heat. Avoid storing it near heaters, stoves, or direct sunlight.
• Store Seasonique in its original packaging or container to protect it from light and air exposure.
• Store Seasonique in a location that is inaccessible to children and pets. Birth control pills can be harmful if ingested by children or animals.
• Before taking Seasonique, check the expiration date on the packaging. Do not use Seasonique if it has expired.

[Note: Discuss with your healthcare professional about the proper disposal of any unused Seasonique birth pills and any questions you may have regarding their storage.]

Seasonique Interactions

• Warfarin
• Phenytoin
• Barbiturates
• Topiramate
• Carbamazepine
• Rifampin
• St. John’s Wort
• Bosentan
• Griseofulvin
• Modafinil
• HIV medications (ritonavir)
• Hepatitis C medications (telaprevir)
• Certain antibiotics (rifabutin, clarithromycin)
• Antifungal medications (ketoconazole, itraconazole)
• Protease inhibitors (indinavir, nelfinavir)
• Anti-seizure medications (felbamate, oxcarbazepine)
• Anti-anxiety medications (diazepam, lorazepam)
• Antidepressants (fluoxetine, paroxetine)
• Anti-inflammatory medications (ibuprofen, naproxen)
• Immunosuppressants (cyclosporine, tacrolimus)

[Note: This isn’t a complete list, and there could be other drugs that interact with Seasonique. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Seasonique Alternatives

• Jolessa (levonorgestrel-ethinyl estradiol)
• Quasense (levonorgestrel-ethinyl estradiol)
• Camrese (levonorgestrel-ethinyl estradiol)
• Amethia (levonorgestrel-ethinyl estradiol)
• Introvale (levonorgestrel-ethinyl estradiol)
• Ashlyna (levonorgestrel-ethinyl estradiol)
• Daysee (levonorgestrel-ethinyl estradiol)
• Seasonale (levonorgestrel-ethinyl estradiol)
• Lo Ovral (levonorgestrel-ethinyl estradiol)
• LoSeasonique (levonorgestrel-ethinyl estradiol)

[Note: Your doctor will choose the best alternative of Seasonique birth pills for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects of Seasonique.] 

Frequently Asked Questions

How should I start taking Seasonique?

You should take the first tablet of Seasonique on the first Sunday following the start of your period, even if you are still bleeding. If you start Seasonique during the first week, you should also use a hormone-free birth control backup, such as a condom. Take your tablet at the same time every day, even if you are spotting or bleeding. Consult your provider right away if you are experiencing nausea or other side effects.

Can I take Seasonique if I am breastfeeding?

No, you shouldn’t take Seasonique while breastfeeding. There is a possibility that this medication can decrease the quantity as well as the quality of your breast milk. Consult your provider to find out what type of birth control is safe for you and your baby.

Can I take other medications with Seasonique?

Always consult your healthcare provider before taking other medications with Seasonique. Some drugs, like certain antibiotics or seizure medications, may interact with Seasonique, reducing its effectiveness or causing other adverse effects. Your healthcare provider can advise you on the best course of action to ensure your safety and the efficacy of your treatment.

How effective is Seasonique?

When taken correctly, Seasonique is more than 99% effective in preventing pregnancy. However, no birth control process is 100% effective, and it is unable to protect against sexually transmitted diseases. It’s crucial to discuss with your healthcare professional to determine if Seasonique is the right choice for you.

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