
Ivermectin



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Soolantra (ivermectin) Cream, 1% is a prescription topical medication indicated for the treatment of inflammatory lesions of rosacea in adult patients. It contains ivermectin, which has anti-inflammatory properties and is believed to reduce skin inflammation associated with rosacea. Soolantra cream is for topical use only and should be applied exactly as directed by a licensed healthcare provider.
| Brand Name | Soolantra |
|---|---|
| Generic Name | Ivermectin |
| Strength | 1% |
| Dosage Form | Topical cream for external use |
| FDA Status | FDA‑approved |
| Prescription Required | Yes |
| FDA‑Approved Indication | Treatment of inflammatory lesions (papules and pustules) of rosacea in adults |
| Common Side Effects | Mild skin irritation, burning sensation, itching (pruritus) |
| Serious but Rare Side Effects | Allergic reactions, severe dermatitis |
| Contraindications | Known hypersensitivity to ivermectin or any component of the formulation |
| Storage | Store at 20°C-25°C (68°F-77°F); protect from freezing |
| Use Restrictions | For topical use only; avoid eyes, lips, and mouth; not for oral, ophthalmic, or intravaginal use |
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According to FDA-approved labeling, Soolantra (ivermectin) cream, 1% is indicated for:
Soolantra (ivermectin) Cream, 1% contains ivermectin, which has anti-inflammatory and antiparasitic properties. The exact mechanism of action of Soolantra in the treatment of inflammatory lesions of rosacea is not fully understood. However:
Here are general usage guidelines on how to use Soolantra 1% for rosacea treatment:
This is not a complete list of Soolantra side effects. If you notice other adverse reactions, tell your doctor right away.
| Common Side Effects | Rare or Serious Side Effects |
|---|---|
| Skin redness or irritation at application site | Severe skin irritation or dermatitis |
| Burning or stinging sensation | Allergic reactions (rash, itching, swelling) |
| Itching at the application site | Skin infection in the treated area |
| Dryness of the skin | Severe swelling or blistering |
| — | Hypersensitivity reactions (rare) |
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There is limited data on overdose with Soolantra 1% cream. Excessive application may increase the risk of local skin reactions.
Possible effects of using too much Soolantra include:
If accidental ingestion occurs or severe reactions develop, seek medical attention or call the poison control center right away.
The following warnings outline potential risks associated with using Soolantra 1% cream:
Hypersensitivity Reactions
Local Skin Reactions
If severe irritation develops, discontinue use & consult your healthcare provider.
The following precautions provide important safety information to consider before using Soolantra (ivermectin).
For Topical Use Only
Lactation
Pregnancy
Pediatric Use
If Soolantra is not suitable or causes irritation, your healthcare provider may recommend other rosacea treatments. These Soolantra alternatives depend on whether the patient has inflammatory lesions or persistent facial erythema.
| Brand Name | Generic Name | Drug Class |
|---|---|---|
| MetroGel / MetroCream / MetroLotion | Metronidazole | Topical anti-inflammatory/antimicrobial |
| Finacea (Gel/Foam) | Azelaic acid | Topical anti-inflammatory/antimicrobial |
| Rhofade | Oxymetazoline HCl | Alpha‑adrenergic vasoconstrictor (for persistent redness) |
| Mirvaso | Brimonidine tartrate | Alpha‑2 adrenergic agonist (for persistent redness) |
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The FDA-approved labeling for Soolantra (ivermectin) 1% cream does not report clinically significant drug interactions. No formal drug interaction studies were conducted.
Because Soolantra is applied topically and systemic absorption is low, significant systemic drug interactions are not expected. Patients should inform their provider of all prescription and OTC medications they are taking before starting treatment.
| Feature | Soolantra (Ivermectin 1% Cream) | Topical Metronidazole (0.75–1%) | Azelaic Acid (Finacea 15% Gel/Foam) | Oxymetazoline (Rhofade 1% Cream) | Brimonidine (Mirvaso 0.33% Gel) |
|---|---|---|---|---|---|
| Active Ingredient | Ivermectin | Metronidazole | Azelaic acid | Oxymetazoline HCl | Brimonidine tartrate |
| FDA‑Approved Indication | Inflammatory lesions (papules and pustules) of rosacea | Inflammatory lesions of rosacea | Inflammatory lesions of rosacea | Persistent facial erythema (redness) of rosacea | Persistent facial erythema (redness) of rosacea |
| Typical Use | Apply once daily | Apply once or twice daily | Apply twice daily | Apply once daily | Apply once daily |
| Primary Benefit | Reduces inflammatory bumps and pustules | Reduces inflammatory bumps and pustules | Reduces inflammatory bumps and pustules | Temporarily reduces persistent redness | Temporarily reduces persistent redness |
| Common Side Effects | Skin burning sensation, irritation, pruritus | Dryness, irritation, stinging | Burning, stinging, tingling | Application site dermatitis, erythema | Flushing, erythema, burning sensation |
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Many patients choose to buy Soolantra from Canada because it offers significant cost savings options compared to U.S. retail prices without compromising on quality or safety. At Polar Bear Meds, we work exclusively with licensed Canadian and international pharmacies that follow strict regulatory and dispensing standards. A valid prescription from a licensed healthcare provider is required to order Soolantra from Canada.
When you buy Soolantra online from Polar Bear Meds, you benefit from more than just lower prices. We focus on affordability, reliability, and a hassle-free ordering experience. Key benefits include:
The information provided about Soolantra is for general educational purposes only & does not replace professional medical advice, diagnosis, or treatment. Soolantra is a prescription topical medication and should be used only under the guidance of a licensed healthcare provider. Always consult your healthcare professional before stopping, starting, or changing any medication.

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.
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