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Tolterodine Tartrate

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Product Details

Description

Tolterodine Tartrate is an FDA-approved medication available under the brand names Detrol and Detrol LA. It is used to treat an overactive bladder by controlling the frequency of urination. Tolterodine is suitable for only adults; if you are considering this medication for your children, talk to a medical expert. While adults can use it, the dosage recommendations may vary depending on the severity of the medical condition and the form of medicine they take (extended-release or immediate-release). Moreover, Tolterodine is a prescription medication, so do not share it with other individuals, even if they share the same condition. Doing so may increase the risk of side effects.

Tolterodine Tartrate is a prescription medication used primarily to treat and manage symptoms associated with an overactive bladder, such as frequent urination, urgency, and incontinence. This medication contains Tolterodine Tartrate as its active ingredient, which works by relaxing the bladder muscles to help control urination. It is FDA-approved, ensuring its efficacy and safety when used as prescribed by a healthcare professional.

Tolterodine Tartrate is available in tablet and extended-release capsule forms, typically in strengths of 1 and 2 mg. It should be taken orally with water, either with or without food, as directed by your doctor. The medication is generally suitable for adults, but its use in children should be strictly under medical supervision. Tolterodine works by blocking a few receptors in the bladder, thereby reducing spasms and improving bladder control.

Common side effects of this medication may include dry mouth, headache, dizziness, or constipation. It is important to inform your medical provider of any pre-existing conditions, especially glaucoma, liver or kidney issues, or urinary retention, as these may affect your suitability for Tolterodine. In case of a missed dose, take it as soon as or whenever you remember, but avoid doubling up if it’s close to the coming scheduled dose. In case of an overdose, get medical attention immediately. You can store medication in a cool and dry place, but ensure it is away from light and moisture.

Uses and Benefits

This medication is used for the following purposes:

  • Overactive Bladder (OAB): In conditions like OAB, the patient may have a strong need to pee even though the bladder is not full. Tolterodine helps in treating the symptoms associated with overactive bladder, such as frequent urination or loss of bladder control.
  • Urinary Frequency: It helps reduce the number of times you urinate.
  • Urinary Urgency: Helps alleviate the sudden and strong need for urination. 
  • Urge Incontinence: Manages involuntary urine leakage due to a sudden urge to urinate. 
Dosage

What Are the Forms & Strengths of Tolterodine Tartrate?

It comes in the following forms and strengths:

  • Immediate Release Tablets: 1 and 2 mg
  • Extended-Release Capsules: 2 and 4 mg

What Are the Recommended Tolterodine Dosages?

The dosage recommendations for Tolterodine Tartrate depend on several factors, including the type and severity of your medical condition and the form of medication you take. Generally, medical professionals prescribe a starting dose and gradually adjust the drug doses as needed. It is important to note that the dosage recommendations below are only for the average dose. So, if you have been prescribed a different dose, do not change it without consulting your medical practitioner.

Dosage for Urinary Incontinence

Immediate-Release Tablets:

  • Initial Dose: Take 2 mg orally twice a day.
  • Maintenance Dose: Take 1 to 2 mg dose orally twice daily as your doctor prescribes, depending on your treatment’s response and tolerability.

Extended-Release Tablets:

  • Initial Dose: Take 4 mg dose orally once daily.
  • Maintenance Dose: Take 2 to 4 mg of Tolterodine Tartrate once a day, depending on your response to the treatment and tolerability.

Dosage for Urinary Frequency

Immediate-Release Tablets:

  • Initial Dose: Take 2 mg orally twice a day.
  • Maintenance Dose: Take a 1 to 2 mg dose orally twice daily as your doctor prescribes, depending on your treatment’s response and tolerability.

Extended-Release Tablets:

  • Initial Dose: Take 4 mg dose orally once daily.
  • Maintenance Dose: Take 2 to 4 mg of Tolterodine Tartrate once a day, depending on your response to the treatment and tolerability.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

Usage Guide

When you order Tolterodine Tartrate online, knowing its proper consumption is essential. Here are the guidelines on how you can take this medication:

  • Read the medication guide or PIL (patient information leaflet) thoroughly, as it provides detailed steps to take the medication. If you have any questions or concerns, ask a healthcare professional.
  • Follow the dosage recommendations exactly as mentioned on the prescription label.
  • Do not exceed or subceed the doses without consulting a medical expert. Doing so may increase the risk of side effects.
  • Take the medication orally with a glass of water.
  • Swallow the tablets or capsules as a whole.
  • You can take the medication with or without food as your doctor advises.
  • Avoid chewing, crushing, splitting, or breaking the tablets. Doing so may release the drug at once.
  • If you are unable to swallow the medicine, consult your practitioner. They will suggest alternate options that suit your body’s needs.
  • Take the medicines at the same time each day to get the most benefit out of it.
  • Do not abruptly stop taking your medication without consulting a medical provider. This may cause serious complications in the future. So, complete your course of treatment till the days your doctor has advised.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How It Works

Tolterodine Tartrate works by blocking certain receptors in the bladder known as muscarinic receptors. These receptors are responsible for triggering bladder contractions, which can lead to frequent or urgent urination. By restricting these receptors, Tolterodine reduces bladder muscle spasms, allowing the bladder to hold more urine and reducing the urgency & frequency of urination. This helps individuals with overactive bladder symptoms recover better control over their bladder function. However, it is important to note that Tolterodine Tartrate effectively manages these symptoms when prescribed by a healthcare professional.

Side Effects

Common Side Effects of Tolterodine: This medication can cause various side effects that are usually temporary. These reactions can last from a few days to weeks, depending on the severity of the side effects. However, if these reactions stay for a longer time and get intense, visit your doctor right away. Common side effects of Tolterodine Tartrate may include:

  • Dizziness: Tolterodine Tartrate may cause dizziness as a side effect. This can occur due to its action on the nervous system, which affects the body’s balance mechanisms. Users might feel unsteady or lightheaded, particularly when getting up suddenly from a sitting or lying position. Moving slowly and sitting or lying down if you feel dizzy is advisable.
  • Drowsiness: Another common side effect of Tolterodine Tartrate is drowsiness. Although this medication can be soothing, it can make users feel unusually tired or sleepy. This can impact daily activities, especially tasks that need alertness, like driving or operating machinery. Users are advised to take precautions and not engage in activities that demand concentration if they experience this side effect.
  • Indigestion: Tolterodine Tartrate may cause gastrointestinal disturbances such as indigestion. Users might experience symptoms like stomach discomfort, bloating, and heartburn. Eating smaller, frequent meals & avoiding spicy or fatty foods may help manage these symptoms.
  • Blurred Vision: Blurred vision can occur as a side effect of Tolterodine Tartrate due to its bladder-selective anticholinergic properties, which affect the eye muscles and reduce tear production. This can make focusing on details difficult and temporarily impair vision. If this occurs, users should avoid tasks that require sharp visual acuity until the effect subsides.
  • Constipation: Tolterodine Tartrate can lead to reduced bowel movements, resulting in constipation. This is because the medication slows food movement through the digestive tract, part of its mechanism for controlling bladder contractions. To alleviate this side effect, users are encouraged to drink lots of water, increase fiber intake, and engage in regular physical activity.
  • Dry Mouth: Patients taking Tolterodine Tartrate often report a noticeable reduction in saliva production, leading to a condition commonly called dry mouth or xerostomia. This can cause discomfort, an increased risk of tooth decay, and difficulties in speaking and swallowing. To manage this, patients are advised to drink water regularly and chew sugar-free gum to stimulate saliva production and maintain good oral hygiene.
  • Headache: Tolterodine Tartrate can cause headaches in some individuals. These headaches might range from mild to moderate pain and might occur periodically. Managing stress, staying hydrated, and getting regular sleep can help mitigate these headaches. Under medical guidance, over-the-counter pain relievers may also be used.
  • Dry Eyes: Similar to its effect on salivary glands, Tolterodine Tartrate can reduce tear production, leading to dry eyes. This might cause irritation, a gritty eye feeling, or a burning sensation. Eye lubricants or artificial tears can help alleviate these symptoms. Patients should consult their healthcare provider if the condition persists or worsens.
  • Diarrhea: Although less common, Tolterodine Tartrate may cause diarrhea in some users. If not managed properly, this could lead to dehydration. Patients should ensure adequate fluid intake and may consider dietary adjustments. If diarrhea is severe or persistent, medical advice should be sought.
  • Stomach Pain or Upset: Taking Tolterodine Tartrate can lead to gastrointestinal disturbances, including stomach pain or a general upset stomach. Eating mild, non-spicy foods and avoiding large meals can help ease these symptoms. Consulting a healthcare provider is crucial if stomach pain worsens or is accompanied by other signs and symptoms like vomiting.
  • Joint Pain: Some individuals on Tolterodine Tartrate may experience joint pain, affecting mobility and quality of life. Maintaining an active lifestyle with regular, gentle exercise and applying heat or cold packs might provide relief. Over-the-counter pain relievers and consulting with a healthcare professional for appropriate pain management strategies are also recommended.

Serious Tolterodine Tartrate Side Effects: Besides the above common effects, Tolterodine can lead to several adverse reactions, which can be life-threatening. Talk to a medical professional immediately if you notice any unusual signs that seem concerning. Serious side effects of Tolterodine may include:

  • Vision Changes: Tolterodine Tartrate may cause vision changes, including blurred vision and difficulty focusing, due to its bladder-selective anticholinergic properties, which affect ocular muscle control. 
  • Extreme Abdominal Pain: While taking Tolterodine Tartrate, some individuals may experience severe abdominal pain, a serious side effect that requires immediate medical attention. This pain can indicate severe constipation or even more critical conditions like bowel obstruction. 
  • Kidney Infection: Tolterodine can sometimes lead to kidney infections, which are serious and can cause permanent kidney damage if not treated quickly. Signs of a kidney infection include:
    • Lower Back Pain
    • Painful Urination
    • Fever
  • Serious Allergic Reactions: When you consider Tolterodine for overactive bladder treatment, be aware that it can cause serious allergic reactions, including:
    • Hives
    • Skin rash
    • Itching
    • Swelling on the lips, tongue, or face
    • Trouble swallowing
    • Nausea
    • Vomiting
  • Confusion: When taking Tolterodine Tartrate, some individuals may experience confusion, a decreased ability to think clearly, difficulties with concentration, and struggles with memory retention. This side effect can be particularly problematic in elderly patients or those with pre-existing cognitive impairments, as the drug can affect neurological function. 
  • Irregular Heartbeats: When you buy Tolterodine online, it may cause irregular heartbeats, a condition where the heart beats too quickly, slowly, or with an irregular rhythm. This side effect occurs because the medication can interfere with the electrical signals that regulate heartbeat, particularly in patients with heart conditions. Symptoms like chest pain, heart palpitations, or fainting spells are signs of this serious side effect and require immediate medical attention.
  • Hallucinations: A rare but serious side effect of Tolterodine Tartrate is hallucinations, which involve perceiving things that are not present, such as seeing or hearing things that aren’t there. This may occur when the medication affects the brain’s processing of sensory information. Hallucinations can cause significant distress and disorientation, leading to fear or unsafe behavior.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Warnings

Tolterodine Tartrate can cause severe side effects in certain patients, or it may not be an ideal treatment option for specific populations due to their medical conditions. So, if you are using Tolterodine Tartrate, you should remain cautious as it has several warnings, which are as follows:

  • Allergic Reactions: This medication can cause severe allergic reactions, including anaphylaxis and angioedema. These reactions can be extremely life-threatening, requiring immediate medical attention. If you experience rash, itching, dizziness/lightheadedness, trouble breathing or swallowing, and swelling on the face, hand, mouth, or throat, visit your doctor immediately.
  • Dryness in the Mouth, Nose & Throat: Tolterodine may cause dryness in the mouth, throat & nose. To relieve the mouth dryness, you can use sugar-free candy, a saliva substitute, and melt ice pieces in the mouth. However, consult a medical professional if the problem continues for more than two weeks. Persistent mouth dryness can increase the risk of dental diseases, such as tooth decay, fungus infections, and gum diseases. 

What Are the FDA Boxed Warning for Tolterodine Tartrate?

Boxed warnings, also called black-boxed warnings, are among the most stringent guidelines issued by the FDA. These warnings alert doctors and patients about the harmful effects of a particular drug, which can be life-threatening if overlooked. Tolterodine Tartrate does not have any boxed warnings, meaning it is safe to use. However, its safety is based on the precautions you take. Therefore, if you are taking this drug, follow the instructions provided by your medical practitioner. If you have any concerns or notice any unusual symptoms, it’s best to consult with an expert.

Safety Guide

When considering treatment with Tolterodine Tartrate, patients should discuss every risk and benefit with their medical practitioner. Here are some of the precautions that you can take before using Tolterodine Tartrate:

  • Before using this medication, tell your healthcare practitioner if you have any allergies or are allergic to Tolterodine, fesoterodine, toviaz, or any of the medication’s ingredients. The product may contain certain inactive components that can cause allergic reactions.
  • When considering treatment with this medication, ensure to tell your doctor about your or your family’s medical history, especially of:
    • Liver problems
    • Kidney problems
    • Stomach or intestinal problems
    • Eye issues such as narrow-angle glaucoma
    • Myasthenia gravis
    • QT prolongation
    • Weak urine stream
  • If you are undergoing surgery or medical procedure, inform your doctor about the products you use. This includes all prescription drugs, over-the-counter medications, and herbal products.
  • Tolterodine can cause blurred vision. So, patients are recommended to avoid driving or using heavy machinery until they know how adversely the medication affects them.
  • If you are taking this medication with strong CYP3A4 inhibitors, consult a medical expert. They will reduce your dosage.
  • Limit the consumption of tea, coffee, alcohol, or any caffeinated soda during your treatment with Tolterodine, as these drinks may exacerbate the symptoms.
  • This medicine can cause dry eyes and blurred vision. Therefore, if you wear contact lenses, you may feel discomfort. Consult an eye specialist if the discomfort does not go away or gets intense over time.
  • Tolterodine can make you sweat less than usual. So, when taking this medication, avoid extreme heat as your body temperature can increase to dangerous levels, leading to heat stroke.
  • Visit your doctor frequently when taking this drug. They will check your progress reports and see if the medicine is working properly or not.
  • It is not clear whether Tolterodine passes into the breast milk or not. If you are a nursing mother, consult a medical expert first.
  • If you are pregnant or planning to have a baby, talk to a medical professional, as it is unclear if the medicine harms the baby or not. Discuss every risk and benefit to your doctor before starting treatment with Tolterodine.


Contraindications

It is contraindicated in patients with:

  • Urinary/gastric retention
  • Hypersensitivity reactions to fesoterodine, Tolterodine, or any of the ingredients present in the medication’s formulation.
  • Uncontrolled closed-angle glaucoma
Missed Dose

Generally, it is advisable not to miss any doses of Tolterodine Tartrate, but if someone forgets, they should:

  • Take the tablets as soon as possible or whenever they remember.
  • If it is almost time for the next dose, omit the missed dose and follow the regular dosing schedule as a medical professional instructed.
  • Remember not to take double doses of the prescribed medication just for the sake of making up for the missed dose. This may cause adverse side effects.
  • Use medication apps or set reminders on your mobile phone to avoid skipping any doses.
  • Take each dose at the same time every day to get the most benefit out of it.
  • If patients are still unsure about the missed doses, talk to an expert physician. They will guide each patient and suggest alternate options suiting their body needs.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

Overdose

While patients are educated enough to know the complications of overdose, there are times when they mistakenly take an excessive amount of Tolterodine Tartrate tablets. In such cases, patients are advised not to panic and instead look for unusual signs like trouble breathing and fainting. If you are experiencing such overdose symptoms, visit the nearest clinic or get medical assistance immediately by calling 911.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

Storage Guide

Proper storage of Tolterodine for overactive bladder treatment is essential to maintain its effectiveness. Follow these guidelines to ensure that Tolterodine Tartrate is stored correctly:

  • Store the tablets or medication at a controlled room temperature of 25ºC with excursions permitted to 15 to 30ºC or 59 to 86ºF.
  • Keep the tablets in a dry place.
  • Protect the medication from moisture, heat, and light.
  • Do not flush the medication down the toilet.
  • Discard the product when not in use.
  • Keep the medicine somewhere safe in a locked container and store it away from children and pets.
  • Place safety locks on the container to avoid poisoning the child. There are certain products in the market that are not completely child-resistant.
  • Do not use a medication if its expiration date has passed. The expiration date is the last day of the month mentioned on the back of the prescription label or carton.
  • You should dispose of the medications in such a way that children and animals cannot consume them, as it may cause accidental overdose and death if someone else consumes them.
  • Ask a medical professional how to discard the product properly without damaging the environment.
  • The best way to eliminate unwanted medications is to give them in the medicine take-back program.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Interactions

Drug interactions occur when one or more medications are taken simultaneously. These interactions can either raise the risk of developing side effects in certain patients or affect the functioning of one of the drugs. Either way, it results in adverse reactions. Therefore, patients need to be aware of the drugs that may interact with their Tolterodine Tartrate medication. There are 375 drugs that can interact with Tolterodine Tartrate. Some of them are listed below:

  • Mavorixafor
  • Potassium chloride
  • Potassium citrate
  • Topiramate
  • Zonisamide
  • Alfentanil
  • Allopurinol
  • Bicalutamide
  • Biperiden
  • Ceritinib
  • Cevimeline
  • Darifenacin
  • Darunavir
  • Eluxadoline
  • Entrectinib
  • Fexinidazole
  • Fluconazole
  • Givinostat
  • Givosiran
  • Hydrocodone
  • Hydromorphone
  • Imatinib
  • Imipramine
  • Ketoconazole
  • Levorphanol
  • Lonafarnib
  • Nalbuphine
  • Nebivolol
  • Orphenadrine
  • Osilodrostat
  • Quinidine
  • Quinine
  • Rifapentine
  • Risperidone
  • Sertraline
  • Sirolimus
  • Tapentadol
  • Tarlatamab
  • Umeclidinium
  • Voriconazole
  • Voxelotor
  • Warfarin
  • Zafirlukast
  • Ziprasidone

What Are the Other Tolterodine Tartrate Interactions?

Apart from the various drug interactions, Tolterodine Tartrate can interact with the following:

  • Disease Interaction: Besides the above drugs, this medicine also has several disease interactions:
    • Angle-closure glaucoma
    • GI/urinary obstruction
    • CNS
    • Hepatic dysfunction
    • Myasthenia gravis
    • QT prolongation
    • Renal dysfunction
  • Interaction with Alcohol: Consult your healthcare provider before using Tolterodine and consuming alcohol together. Drinking alcohol while taking this medication should be approached with caution, as it can increase side effects such as drowsiness and dizziness. It’s important to stick to the prescribed dosages and avoid activities that require sharp mental focus. If your doctor approves the concurrent use of Tolterodine and alcohol, an adjusted dosage might be necessary to manage both safely.
  • Caffeine-containing Foods/Beverages: Consuming caffeinated foods and beverages can reduce the effectiveness of Tolterodine, as caffeine has a diuretic effect that increases urination. Consider limiting your intake of caffeine sources such as coffee, cola, tea, and certain herbal supplements while taking Tolterodine. Monitoring your caffeine intake can help maintain the drug’s efficacy and minimize potential adverse interactions.
  • Grapefruit Juice: Grapefruit juice can intensify the side effects of Tolterodine. To avoid exacerbating these effects, maintain a consistent level of grapefruit intake while on this medication, and do not make significant changes without consulting your healthcare provider. Be vigilant about monitoring for new or worsening symptoms, including constipation, dizziness, urinary difficulties, dry mouth and eyes, vision changes, rapid heartbeat, or confusion. 

[Note: This isn’t a complete list, and there could be other drugs that interact with Tolterodine Tartrate. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Alternatives

People usually take alternative drugs for many reasons. In some cases, the prescribed medication may not be an ideal option for them due to their medical conditions. On the other hand, they may not achieve the results they are aiming for. Therefore, you should talk to a medical professional before you start a particular treatment or if you want to change your medication. They may help you decide which medication is best suited for you. Some of the alternatives to Tolterodine Tartrate are as follows:

  • Gemtesa
  • Vibegron
  • OnabotulinumtoxinA
  • VESIcare
  • Botox
  • Darifenacin
  • Oxybutynin

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Cost & Coupons

It is important to note that the cost of Tolterodine Tartrate is not the same everywhere. The actual price of these tablets depends on several factors, including your insurance plan, location, and the pharmacies you use. Tolterodine Tartrate, with its therapeutic qualities, can be expensive for certain patients. Here, insurance coverage plays a significant role. You can buy your medication at affordable rates with an insurance coverage plan. However, not all drugs/medications are covered under the insurance plan. If you are residing in America and searching for affordable pharmacies to manage your medication’s cost, reach out to Polar Bear Meds. Here, you can buy Tolterodine Tartrate online from Canada in the USA at discounted rates. Moreover, first-time buyers can use the Tolterodine Tartrate coupon code WELCOMEPB10 to receive a 10% discount on their first order.

FAQ

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AtPolarBearMeds.com, we assure you the most affordable price to buy Tolterodine Tartrate online from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently buy Tolterodine Tartrate online to treat an overactive bladder at a substantial cost, call us at 1-888-779-2193 toll-free.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

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