Varenicline Tartrate

Varenicline Tartrate 

Varenicline tartrate is an FDA-approved medication that helps in smoking cessation. However, this medicine should be used in combination with education and counseling to help people quit smoking. Varenicline is specially formulated to reduce nicotine cravings and withdrawal symptoms that happen when people decide to stop smoking. Since it is a prescription drug, Varenicline tablets are only available with a medical professional’s label. Therefore, patients are advised not to share their medication with other individuals even if they want to stop smoking. Doing so can cause several complications as not every patient has the same medical needs. If you’re looking to buy Varenicline tartrate online, ensure that you do so from a reputable source and under the guidance of a healthcare provider.

Product Overview

Varenicline Tartrate is a prescription medication specifically designed to assist individuals in quitting smoking. Containing the active ingredient Varenicline, it functions as a nicotinic receptor partial agonist. This means it helps reduce cravings and withdrawal symptoms associated with smoking cessation while making smoking less pleasurable. Clinically proven and FDA-approved, Varenicline tartrate for smoking cessation has been shown to support long-term abstinence from smoking. Available in tablet form with strengths of 0.5 mg and 1 mg, Varenicline tartrate is typically taken once or twice daily, either with or without food, based on your healthcare provider’s recommendations. The medication works by partially activating nicotine receptors in the brain, which helps reduce cravings. 

It also blocks the pleasurable effects of nicotine, making smoking less rewarding and encouraging you to stay smoke-free. If you are looking to buy Varenicline tartrate online, it is important to ensure that you are purchasing it from a reputable source and under the guidance of a healthcare professional. Varenicline for nicotine withdrawal support can be an effective part of your quit-smoking plan but should be used alongside other support tools, such as counseling and behavioral therapy.

Common side effects of Varenicline tartrate include nausea, headache, and vivid dreams. If you experience any unusual symptoms, it is essential to consult your doctor. If you miss a dose, take it as soon as you remember unless it’s close to your next scheduled dose. In case of overdose, seek immediate medical attention. For optimal results, always follow your healthcare provider’s instructions, inform them of any existing medical conditions—especially mental health issues—and store the medication in a cool, dry place out of reach of children. By incorporating Varenicline tartrate into your smoking cessation strategy, you can take an important step toward a smoke-free life.

What Are the Uses of Varenicline Tartrate?

This medication has the following uses:

• Helps in Smoking Cessation: Varenicline helps people quit smoking by minimizing the cravings and withdrawal symptoms.
• Blocks Nicotine Receptors: The medicine blocks nicotine effects on the brain, making smoking less pleasurable.
• Reduces Relapse: It helps reduce the risk of relapse in individuals who have already quit smoking.

What Are the Forms & Strengths of Varenicline Tartrate?

It is available in the form of an oral tablet with the following strengths:

• 0.5 mg, and 
• 1 mg

What Are the Recommended Dosage of Varenicline Tartrate?

The dosage recommendations for Varenicline tartrate depend on several factors, including the type and severity of your medical condition and the form of medication you take. Generally, medical professionals prescribe a starting dose and gradually adjust the drug doses as needed. It is important to note that the dosage recommendations below are only for the average dose. So, if you have been prescribed a different dose, do not change it without consulting your medical practitioner.

Dosage for Adults

• Select a date when you want to quit smoking & start taking Varenicline one week before the selected date.
• You can also begin the treatment and then quit smoking within 8 to 35 days of the treatment.
• Usually, the starting dose of Varenicline is 1 mg twice daily, followed by a 1-week titration as follows:
  • On Days 1 to 3: Take a 0.5 mg tablet once daily.
  • On Days 4 to 7: 0.5 mg twice a day.
  • On Day 8 till the completion of the treatment: 1 mg twice a day.
• If you are successful in quitting smoking after 12 weeks, continue taking 1 mg tablets for another 12 weeks every 12 hours.
• Keep taking Varenicline for another 12 weeks, making it a total of 24 weeks of treatment.

Dosage for Patients with Renal Impairment

• Mild to Moderate Kidney Problems: No need to change the dosing schedule.
• Severe Kidney Problems: Start by taking 0.5 mg once daily. If needed, increase the dosage to 0.5 mg twice daily.
• End-stage Kidney Disease on Dialysis: Do not take more than 0.5 mg once a day.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use Varenicline Tartrate?

When using Varenicline Tartrate to help quit smoking, it’s important to follow the correct dosage and administration guidelines to ensure the medication works effectively. This medication should be taken as part of a comprehensive smoking cessation plan, and your healthcare provider will provide specific instructions tailored to your needs. Below are the key steps and recommendations for using Varenicline Tartrate safely and effectively:

• Before you start taking this medicine, make sure to read the medication guide or PIL (patient information leaflet) provided by your healthcare practitioner. This will give you detailed insight into administration steps. If you have any questions, ask your doctor.
• Follow the dosing recommendations that are mentioned on your prescription label. 
• Do not exceed or subceed the doses and the duration of the treatment. 
• Take the medicine one week before quitting and start on a low dose, gradually increasing the dose to 1 mg twice daily after eight days.
• You can take the medicine with food or immediately after your meal, with a full glass of water. Doing so will reduce potential nausea from the medications.
• Since Varenicline does not contain nicotine, it works differently than nicotine replacement medications.
• Besides the above ways, there are three more ways to take your medicine, and these are:
  • Choose the date from which you will stop smoking and start taking the medicine one week before that date. Take it for 12 weeks. Then, your doctor will decide if you should continue the treatment for another 12 weeks.
  • You can take the medicine for at least eight days before choosing a quit date. Continue taking Varenicline for a total of 12 weeks. If you stop smoking during this time, your doctor might recommend taking Varenicline for another 12 weeks.
  • Lastly, if you are unable to quit smoking, you can take the medicine and cut down on your smoking consumption during the first 12 weeks of the treatment. 
• Swallow the tablets as a whole.
• Avoid chewing, crushing, splitting, or breaking the tablets. Doing so may release the drug at once. 
• If you are unable to swallow the medicine, consult your healthcare practitioner. They will suggest alternate options that suit your body’s needs.
• Do not abruptly stop taking your medication without consulting a medical provider. This may cause serious complications in the future. So, complete your course of treatment till the days your doctor has advised.  
• Use the strength of medication that has been prescribed to you by your healthcare provider. Avoid switching brands without consulting a medical expert.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Varenicline Tartrate Work?

Varenicline tartrate works by targeting nicotine receptors in the brain. It partially activates these receptors, which aids in suppressing cravings & withdrawal symptoms when a person decides to quit smoking. At the same time, it blocks nicotine from fully activating these receptors, diminishing the pleasurable effects of smoking. This dual action makes smoking less rewarding and helps individuals resist the urge to smoke. By reducing both the desire to smoke and the satisfaction gained from smoking, Varenicline tartrate effectively supports individuals in their efforts to quit smoking and maintain long-term abstinence.

Important Safety Information for Using Varenicline Tartrate

What Are the Side Effects of Varenicline Tartrate?

Common Side Effects of Varenicline Tartrate: This medication can cause various side effects. Although these reactions are generally common and stay for a few days to weeks, you should not overlook them. If the following side effects do not go away or stay longer than the mentioned time period, reach out to a medical professional right away. Common side effects of Varenicline tartrate may include:

• Constipation: Varenicline can affect your digestive system, causing constipation. This means you may have less frequent or difficult bowel movements. Drinking plenty of water, eating fiber-rich foods, and exercising regularly can help reduce this side effect.
• Gas: Some people may experience bloating or excess gas. This happens because varenicline can slow down digestion, leading to more gas buildup. Over-the-counter remedies like simethicone or adjusting your diet can help alleviate this discomfort.
• Vomiting: Nausea and vomiting are common side effects when taking varenicline, especially in the beginning. This may happen due to the way the medication interacts with the brain’s receptors. If vomiting persists, consult your doctor, as adjustments to your dose may be needed.
• Sleep Problems: Varenicline can interfere with sleep patterns, leading to insomnia or restless sleep. This may include difficulty falling asleep or waking up too early. If sleep disturbances become problematic, talk to your healthcare provider about potential solutions or adjustments to your treatment.
• Strange Dreams: Varenicline can affect the quality of your sleep and lead to vivid, strange, or unusual dreams. These dreams may be more intense and frequent, which can disrupt sleep. If this side effect becomes bothersome, discuss it with your doctor for possible solutions.
• Nicotine Withdrawal Symptoms: As varenicline works to reduce cravings for nicotine, you may experience symptoms of nicotine withdrawal, such as:
  • Urge to smoke: Strong cravings to smoke, especially if you’ve recently quit, are common during the treatment period.
  • Depression: A feeling of sadness or hopelessness may emerge as you adjust to quitting smoking due to the withdrawal from nicotine.
  • Trouble sleeping: Nicotine withdrawal can make it difficult to stay asleep or fall asleep, leading to frequent awakenings or insomnia.
  • Irritability: A common symptom of nicotine withdrawal, irritability can lead to frustration or a short temper, making it harder to stay calm.
  • Frustration: The frustration of quitting smoking, combined with withdrawal, may lead to feelings of anger or being easily upset.
  • Anxiety: Anxiety can be heightened during nicotine withdrawal as the body adjusts to the absence of nicotine.
  • Difficulty Concentrating: A lack of nicotine can cause trouble focusing or concentrating, affecting daily tasks or work.
  • Anger: Anger is a common reaction to the discomfort of nicotine withdrawal, which can make emotions feel more intense than usual.
  • Restlessness: Feeling restless, agitated, or unable to relax is another symptom of nicotine withdrawal when taking varenicline.

• Reduced Heart Rate: Varenicline may cause a slight reduction in heart rate as it works to curb nicotine cravings. While this typically isn’t dangerous, contact your medical expert if you experience dizziness, weakness, or fatigue.
• Feeling Hungry: Some people find that their appetite increases as they quit smoking. Varenicline can also contribute to changes in your hunger signals, making you feel hungrier than usual, which can lead to overeating.
• Weight Gain: Along with increased hunger, weight gain may occur during nicotine withdrawal. This happens because smoking often suppresses appetite, and quitting may lead to a greater desire to eat. Maintaining a healthy diet and exercise routine can help manage this side effect.

Serious Side Effects of Varenicline Tartrate: Other than the above side effects, the medicine can result in various adverse reactions that can cause fatal situations. If you notice any unusual signs that seem concerning, talk to a healthcare provider. Serious side effects of Varenicline tartrate may include:

• Mental health problems. Its symptoms are:

• • • Behavioral changes: These may include how you behave, feel, or think. For example, you might become irritable, anxious, or detached from reality. It’s important to report any sudden changes to your doctor.
    • Agitation: This is a feeling of restlessness or nervous excitement. People experiencing agitation may have difficulty staying still, overly alert or on edge. This can be distressing and may require medical attention.
    • Depressed mood: A common side effect is feeling sad, hopeless, or emotionally numb. This may indicate depression, especially if it persists for several days. It’s important to seek support if you experience these feelings regularly.
    • Suicidal thoughts: Some people may have thoughts of self-harm or suicide. This is a serious side effect and requires immediate intervention. If you experience these thoughts, contact a healthcare provider or emergency services right away.
    • Hostility: You may feel unusually angry or hostile, even in situations where it’s not appropriate. Hostility can lead to irritability and conflicts, so if this happens, it’s crucial to talk to your doctor for adjustments or treatment.
    • Seizures: Seizures are a rare but serious side effect, causing a loss of control of body movements, convulsions, or muscle spasms. This can be dangerous, and you should seek immediate medical help if a seizure occurs.

• Cardiovascular problems. Its signs are:

• • • Chest discomfort: This can feel like tightness, pressure, or pain in your chest. It might indicate an underlying heart issue, so it’s important to consult your doctor if you experience any chest discomfort.
    • Pain in one or both arms, back, jaw, neck, or stomach: Pain radiating from the chest to other areas like the arms, back, or jaw can be a sign of a heart-related issue, including a heart attack. Immediate medical attention is required in this case.
    • Breath shortness: Difficulty breathing or feeling like you can’t take a deep breath could indicate a heart or lung issue. This is a serious symptom and should not be ignored.
    • Sweating: Excessive sweating, especially if accompanied by other symptoms like chest pain or breathlessness, may indicate a cardiovascular issue, such as a heart attack.
    • Nausea: Nausea, often paired with dizziness or chest pain, may signal a heart issue or other severe conditions. If you feel nauseous and have different symptoms, seek medical help.
    • Vomiting: Along with other cardiovascular symptoms, can be an alarming sign of a heart attack or related issues. Immediate medical evaluation is needed.
    • Sleepwalking: It involves walking or performing tasks while not fully awake. This can lead to potential injuries or accidents. If sleepwalking occurs, it’s essential to talk to your doctor, as it might indicate deeper neurological issues or a reaction to medication.

• Allergic reactions. Its symptoms include:

• • • Racing heart: A fast or irregular heartbeat can indicate an allergic reaction. Palpitations, dizziness, or chest tightness may accompany this. If this happens, seek immediate medical help.
    • Fever: An unexpected fever could indicate an allergic reaction, especially if it occurs with other symptoms like swelling or rashes. A fever should be monitored closely, and medical advice is essential.
    • Swollen lymph nodes: Enlarged lymph nodes, especially when accompanied by fever or infection, can indicate an allergic response. If these become painful or swollen, seek medical attention.
    • Throat tightness: Tightness or swelling in the throat can obstruct breathing and is a severe allergic reaction known as angioedema. Seek immediate medical care if this happens.
    • Stomach cramps: Severe stomach cramps or pain can be a symptom of an allergic reaction. These may cause discomfort, nausea, or bloating. If they persist, you should contact your healthcare provider.
    • Joint pain: Swollen or painful joints, particularly with other symptoms like fever, may indicate an allergic reaction that requires attention from your doctor.

• Serious skin reactions. Its signs are:

• • Rash: A rash can appear on the skin and may indicate an allergic reaction. If the rash is severe or disappears, seek medical help.
  • Swelling on the face, mouth, throat, or neck: This could indicate an allergic reaction called angioedema. It can cause difficulty breathing and requires urgent medical care.
  • Redness: Skin redness may occur due to an allergic reaction. It’s important to seek medical advice if it’s widespread or painful.
  • Peeling of the skin: This can occur in severe allergic reactions and may be painful or lead to skin damage. If this happens, immediate medical attention is necessary.
  • Trouble breathing: Difficulty breathing and a skin rash or swelling can indicate a severe allergic reaction, a medical emergency requiring immediate attention.
  • Mouth blisters: Blisters in the mouth can be part of a serious allergic reaction or skin condition. Seek medical attention if you notice blisters or sores that are painful or persistent.
  • Red or watery eyes: Eyes that become red, swollen, or produce excessive tears may signal an allergic reaction. This can be uncomfortable and may need treatment to reduce inflammation.
• Angioedema: This condition causes swelling, typically in the face, lips, tongue, and throat. It can lead to serious breathing difficulties and is a medical emergency that requires immediate treatment.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Are There Any Warnings for Varenicline Tartrate?

Varenicline tartrate can cause severe side effects in certain patients, or it may not be an ideal treatment option for specific populations due to their medical conditions. So, if you are using this medication, you should remain cautious as it has several warnings, which are as follows:

• Angioedema and Hypersensitivity Reactions: Patients taking this medication have reported hypersensitivity reactions such as angioedema. In this condition, patients can experience swelling on the face, mouth, neck, throat, or tongue. There have been infrequent reports of fatal angioedema that required medical attention due to respiratory compromise. If you notice such symptoms, discontinue using Varenicline.
• Severe Skin Reactions: While rare, some patients have also reported serious skin reactions, including Steven-Johnson Syndrome and erythema multiforme. These reactions can be life-threatening, so patients are advised to avoid taking this medication. Moreover, if you observe a skin rash with mucosal lesions, reach out to a medical professional.
• Accidental Injury: Varenicline tartrate may cause dizziness, difficulty concentrating, drowsiness, and loss of consciousness. There have also been reported cases of traffic accidents or accidental injuries in patients taking the medicine. Therefore, you should avoid driving or operating any heavy machinery until you know how Varenicline may affect you.
• Cardiovascular Risk: Patients with underlying cardiovascular disease taking Varenicline have a high risk of heart problems. A study with 700 people showed that those taking this medicine may experience nonfatal heart attacks, needing heart surgery, chest pain, and other blood vessel problems.

What Are the FDA Boxed Warning for Varenicline Tartrate?

Boxed warnings, also called black-boxed warnings, are among the most stringent guidelines issued by the FDA. These warnings alert doctors and patients about the harmful effects of a particular drug, which can be life-threatening if overlooked. Varenicline tartrate has the following boxed warning. If you have any concerns or notice any unwanted symptoms, it’s best to consult with an expert.

• Neuropsychiatric Symptoms: People taking Varenicline have experienced severe mental health symptoms. Some of these symptoms are due to nicotine withdrawal; however, it is not necessary; people who are still smoking can notice such symptoms. So, patients should watch out for: 
  • Changes in their behavior
  • Depression
  • Agitation
  • Suicidal thoughts or actions

Many people taking this medication have reported the above symptoms and exacerbation of their existing mental health conditions. Moreover, it is important to note that patients with serious mental health problems, including bipolar disorder, schizophrenia, and major depression, were not included in the initial studies of Varenicline. Therefore, its safety and effectiveness on these patients are unknown. Lastly, if you are taking this medication, you should be aware of these symptoms and report them to a medical practitioner right away.

What Are the Varenicline Tartrate Precautions?

When considering treatment with Varenicline tartrate, patients should discuss every risk and benefit with their medical practitioner. Here are some of the precautions that you can take before using Varenicline tartrate:

• Before starting this medicine, tell your doctor about your allergies or if you are allergic to chantix, tyrvaya, varenicline, or any of the ingredients present in the medication’s formulation. The product may contain certain inactive components that can cause severe allergic reactions.
• Avoid taking this medication unless it has been prescribed to you by a medical expert.
• When considering treatment with Varenicline, you should be aware of the nicotine withdrawal symptoms. This includes:
  • Anxiety and depression
  • Restlessness and trouble sleeping
  • Irritability, frustration, or anger
  • Craving to smoke 
  • Difficulty concentrating
  • Increased appetite and weight gain 
  • Decreased heart rate 
• Before considering treatment with this medicine, inform your healthcare provider about your or your family’s medical history, especially of:
  • Seizures
  • Heart or blood vessel problems
  • Kidney problems
• If you are undergoing surgery or any medical procedure, tell your surgeon or medical expert about the products you use. This include all prescription medications, over-the-counter drugs, or any herbal products.
• Varenicline tartrate may cause CNS depression. So, use the medicine cautiously when performing any tasks that require mental alertness.
• If you are using any nicotine patches to help quit smoking, tell your healthcare professional, as using this patch can increase the risk of the following side effects:
  • Vomiting
  • Headache
  • Nausea
  • Dizziness
  • Upset stomach
  • Tiredness
• Patients have reported cases of sleepwalking during their treatment with Varenicline. Some of these cases even involve harmful behavior towards themselves or others. If you are experiencing sleepwalking, stop taking your medication and inform a medical practitioner.
• It is unknown whether this medicine affects pregnancy or harms the developing baby. So, talk to your healthcare practitioner and discuss every risk and benefit associated with it. They will advise you if the medicine is safe for the baby or not.
• Similarly, it is unknown if Varenicline passes into the breast milk. If you are breastfeeding, consult a medical provider about the safety and effectiveness of the drug. Additionally, watch out for symptoms of a seizure in your baby or if they are having any feeding problems, like spitting up more than usual.

What Are the Contraindications of Varenicline Tartrate? 

It is contraindicated in patients with hypersensitivity reactions to Varenicline or any ingredients present in the formulation of medication.

What If You Missed a Dose of Varenicline Tartrate?

Generally, it is advisable not to miss any doses of Varenicline tartrate, but if someone forgets, they should:

• Take the tablets as soon as possible or whenever they remember.
• If it is almost time for the next dose, omit the missed dose & follow the regular dosing schedule as a medical professional instructed.
• Remember not to take double doses of the prescribed medication just for the sake of making up for the missed dose. This may cause adverse side effects.
• Use medication apps or set reminders on your mobile phone to avoid skipping any doses.
• Take each dose at the same time every day to get the most benefit out of it.
• If patients are still unsure about the missed doses, talk to an expert physician. They will guide each patient and suggest alternate options suiting their body needs.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much of Varenicline Tartrate?

While patients are educated enough to know the complications of overdose, there are times when they mistakenly take an excessive amount of Varenicline tartrate tablets. In such cases, patients are advised not to panic and instead look for unusual signs, such as:

• Nausea
• Vomiting
• Unusual dreams

In more serious cases, you can experience neuropsychiatric symptoms, such as aggression, mood changes, agitation, or even suicidal thoughts. If such symptoms appear, visit the nearest clinic or get medical assistance immediately by calling 911.  

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

How to Store a Varenicline Tartrate?

Storing the medication correctly helps prevent accidental ingestion, maintains its potency, and protects it from external factors that may cause it to deteriorate. It’s also important to follow disposal guidelines to prevent harm to others and the environment. Below are the recommended storage and disposal instructions for Varenicline Tartrate.

• Store the medicine at a temperature of 20°C to 25°C or 68°F to 77°F.
• Keep your medicines somewhere safe with safety locks to avoid poisoning your child. Many products on the market do not come in child-resistant packaging.
• Store the tablets in a locked container, away from the reach and sight of children and pets.
• Do not keep them in moist or damp places like the bathroom or near the sink.
• Do not flush the medication down the toilet.
• Discard the product when not in use.
• Protect them from moisture and direct sunlight.
• Store the tablets in a dry place.
• Do not use a medication if its expiration date has passed. The expiration date is the last day of the month mentioned on the back of the prescription label or carton.
• You should dispose of the medications in such a way that children and animals cannot consume them, as it may cause accidental overdose and death if someone else consumes them.
• Ask a medical professional how to dispose of the medicine properly without damaging the environment.
• The best way to eliminate unwanted medications is to give them in the medicine take-back program.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Varenicline Tartrate?

Drug interactions occur when one or more medications are taken simultaneously. These interactions can either raise the risk of developing side effects in certain patients or affect the functioning of one of the drugs. Either way, it results in adverse reactions. Therefore, patients need to be aware of the drugs that may interact with Varenicline tartrate. Below are some of the drugs that can interact with Varenicline tartrate:

• Cimetidine: An H2 blocker used to reduce stomach acid, can interfere with the metabolism of Varenicline by inhibiting liver enzymes (specifically CYP1A2). This can lead to higher levels of Varenicline in the bloodstream, potentially increasing side effects such as nausea, dizziness, or mood changes. Close monitoring of Varenicline levels may be necessary when used with Cimetidine.
• Dalfampridine: Used to improve walking in multiple sclerosis, may increase the risk of side effects when taken with Varenicline. Both medications can impact central nervous system (CNS) activity, leading to a heightened risk of dizziness, difficulty concentrating, or confusion. Patients should be monitored closely for these symptoms when both drugs are prescribed together.
• Dolutegravir: An antiretroviral medication for HIV, may not have a direct interaction with Varenicline, but both can impact the CNS. Combining the two may increase the likelihood of side effects such as depression, agitation, or sleep disturbances. Monitoring mood changes and CNS effects is advised during co-administration.
• Ethanol: Drinking alcohol while on Varenicline can intensify the risk of neuropsychiatric side effects like mood swings, aggression, or suicidal thoughts. Varenicline already has CNS effects, and alcohol may exacerbate these symptoms, increasing the risk of dizziness, sedation, and impaired judgment. It’s advisable to limit alcohol intake while using Varenicline.
• Lamotrigine: An anticonvulsant, may increase the risk of side effects when taken with Varenicline. Both medications can affect mood and behavior, and combining them could potentially lead to an increased risk of depression, anxiety, or suicidal thoughts. Close monitoring of mood changes is recommended for patients on both drugs.
• Nicotine: When used in conjunction with Varenicline, it may lead to enhanced effects as both substances act on the brain’s nicotine receptors. Varenicline works by reducing the craving and withdrawal symptoms associated with nicotine, but combining it with nicotine replacement therapies (NRT) like patches, gum, or lozenges may increase side effects like nausea or headaches. It’s typically recommended to avoid using both at the same time.
• Ranolazine: Used for angina, it can increase the concentration of Varenicline in the bloodstream. It affects liver enzymes, specifically CYP3A4, and may interfere with how Varenicline is processed, leading to a higher risk of adverse effects such as dizziness or confusion. Monitoring is recommended to adjust dosages if necessary.
• Vandetanib: A drug used for certain types of cancer, can interact with Varenicline by affecting the enzymes responsible for metabolizing the drug. This could increase Varenicline’s blood levels and enhance its side effects, including psychiatric and CNS-related issues like agitation or insomnia. Careful monitoring for side effects is essential if these medications are used together.

What Are the Other Varenicline Tartrate Interactions?

Other than the above drugs, this medication has some disease interactions, too:

• Neuropsychiatric events: Varenicline has been associated with neuropsychiatric side effects such as mood changes, depression, anxiety, agitation, and suicidal thoughts. This is because the medication influences brain chemicals involved in mood regulation. People with a history of mental health conditions should be closely monitored while taking Varenicline. If symptoms worsen, consult your doctor immediately.
• Alcoholism: Combining Varenicline with alcohol may increase the risk of mood swings, aggression, and unusual behaviors. Alcohol can also amplify the sedative effects of Varenicline, causing dizziness or impaired judgment. People with a history of alcohol abuse are advised to limit alcohol consumption or avoid it altogether while taking the medication to reduce these risks.
• CV disease: Varenicline may cause or exacerbate cardiovascular issues like increased blood pressure, heart rhythm irregularities, or chest pain, particularly in people with pre-existing heart conditions. Patients with a history of heart attacks, angina, or other CV diseases should be monitored closely. Notify your healthcare provider if you experience chest discomfort or breath shortness.
• Renal impairment: Varenicline is cleared from the body through the kidneys. In patients with renal impairment, the medication can accumulate in the body, leading to increased side effects, such as nausea or dizziness. People with kidney problems may require dose adjustments or alternative treatments to prevent toxicity. Regular kidney function tests are essential during treatment.
• Seizures: This medication can lower the seizure threshold, making seizures more likely in individuals with a history of epilepsy or brain injuries. Alcohol use or abrupt smoking cessation while on the medication can further increase seizure risk. If you experience a seizure while taking Varenicline, discontinue the medication and seek medical attention immediately.

[Note: This isn’t a complete list, and there could be other drugs that interact with Varenicline Tartrate. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Varenicline Tartrate Alternatives?

People usually take alternative drugs for many reasons. In some cases, the prescribed medication may not be an ideal option for them due to their medical conditions. On the other hand, they may not achieve the results they are aiming for. Therefore, you should talk to a medical professional before you start a particular treatment or if you want to change your medication. They may help you decide which medication is best suited for you. Some of the alternatives to Varenicline tartrate are as follows:

• Bupropion
• Nicotine
• Nicoderm CQ
• Nicorette
• Habitrol
• Clonidine
• Nicotrol Inhaler
• Nortriptyline

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Varenicline Tartrate Cost & Coupons

It is important to note that the cost of Varenicline tartrate can vary depending on several factors, including your insurance plan, location, and the pharmacy you use. For some patients, the price of these anti-smoking tablets can be quite high. Insurance coverage plays a key role in managing the cost of medications. With insurance, you may be able to access affordable Varenicline for quitting smoking, but not all medications are covered under every plan. If you’re based in the USA and looking for ways to manage the cost of Varenicline tartrate, consider checking out Polar Bear Meds. You can buy Varenicline tartrate online from Canada and have it shipped to the USA at discounted rates. Plus, first-time customers can enjoy a 10% discount by using the coupon code WELCOMEPB10 on their first order. This offers a more budget-friendly option for those seeking support with smoking cessation.

Frequently Asked Questions

Is it safe to take Varenicline tartrate?

Varenicline tartrate is generally considered safe when prescribed by a medical professional. However, the medicine can cause some side effects, such as nausea, insomnia, or changes in mood. Therefore, it is essential to discuss any underlying conditions or other medications with your doctor to ensure the medicine is appropriate for you.

Is Varenicline tartrate an anti-depressant medication?

No, Varenicline tartrate is not categorized as an anti-depressant. It is a smoking cessation medication designed to help people stop smoking by reducing cravings and withdrawal symptoms. While it affects certain brain receptors, it is primarily used to aid in smoking cessation, not to treat depression.

What happens when you stop taking Varenicline tartrate?

Patients are generally advised not to abruptly stop taking their medication as it can result in the return of nicotine cravings and withdrawal symptoms. So, it is important to follow your doctor’s advice to taper off the medication to reduce such effects.

Is Varenicline tartrate an addictive medication?

Varenicline tartrate is not considered addictive. It does not have the same effects or produce addictive dependence on nicotine or other substances. However, it does not mean you overlook the importance of an expert’s advice. Take the doses as directed by your doctor to achieve the best results. 

Does Varenicline tartrate cause weight gain?

Varenicline tartrate itself does not directly cause weight gain. However, some individuals may gain weight after quitting smoking due to metabolic changes and eating habits. So, maintain a balanced diet and exercise while quitting smoking to manage any potential weight changes.

Our Guarantee

At PolarBearMeds.com, we assure you the most affordable price to buy Varenicline tartrate online from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently buy Varenicline tartrate online to quit smoking at a substantial cost, call us at 1-888-779-2193 toll-free.