Vraylar

Vraylar is an FDA-approved medication used to treat certain mental health conditions. This prescription drug contains Cariprazines as its active drug that helps in relieving symptoms of bipolar I disorder, major depressive disorder, and schizophrenia. This medication comes in oral capsules that adults can use with a medical professional’s prescription. While considered effective, Vraylar for mental health care management can have serious side effects if the medication is not taken appropriately. Therefore, patients are advised to follow the instructions mentioned on their prescription label. Do not change any dosage range without asking your medical provider. If the condition worsens, immediately seek medical assistance. 

Vraylar is a prescription medication that is FDA-approved to treat schizophrenia and bipolar disorder. It contains Cariprazine, an atypical antipsychotic that helps stabilize mood and reduce symptoms of psychosis by acting on dopamine & serotonin receptors in the brain.

Vraylar is available in oral capsule form, with strengths of 1.5, 3, 4.5, and 6 mg. It is typically taken once daily with or without food, as your medical practitioner prescribes. This medication is suitable for adults diagnosed with schizophrenia or bipolar disorder. The active ingredient, cariprazine, works by regulating neurotransmitter activity in the brain, promoting mental stability, and reducing symptoms such as hallucinations, delusions, and mood swings.

While the medication effectively helps in treating mental health conditions, it can also have certain common side effects, which may include restlessness, extrapyramidal symptoms (such as tremors or stiffness), and weight gain. Moreover, patients should follow their healthcare provider’s instructions closely to avoid potential interactions with other medications or substances. If a person misses their dose of Vraylar, they should take it as soon as possible unless it is almost time for the next dose. However, if someone mistakenly takes an overdose, seek immediate medical attention. Vraylar should be stored at a specific room temperature, away from moist places and heat, and out of reach of children.

This medication is used to treat the following conditions:

• Maniac or Mixed Episodes of Bipolar I Disorder: Maniac episodes (high mood) can last up to 7 days, and if it persists for an extended period, hospitalization is needed. On the other hand, mixed episodes are defined by combined symptoms of mania and depression (low mood). 
• Depressive Episodes of Bipolar I Disorder: This condition is referred to as bipolar depression.
• Major Depressive Disorder or Depression: This condition may result in a constant low mood, difficulty sleeping, and not feeling motivated. To treat such disorders, doctors usually prescribe antidepressants with Vraylar. 
• Schizophrenia: Patients with such disorders may experience symptoms of psychosis like hallucinations and delusions.

Forms & Strengths of Vraylar?

Vraylar comes in the form of an oral capsule with four distinct strengths:

• 1.5 mg
• 3 mg
• 4.5 mg, and
• 6 mg

What Are the Recommended Dosage of Vraylar?

The recommended dosage of Vraylar for mental health care varies depending on the medical condition being treated & the individual patient’s response and tolerability. The dosage given here is generalized, and if your doctor has recommended a different dosage, it is essential to follow your physician or healthcare provider’s instructions to ensure the best outcomes. Do not take it more or less than recommended, in large doses, or more frequently, as it can cause unfavorable side effects.

Dosage for Manic/Mixed Episodes of Bipolar I Disorder

• Usual Dosage: The usual dosage range of Vraylar is between 3 to 6 mg once daily.
• Day 1: On the first day of the treatment, take 1.5 mg.
• Day 2: Later, take a 3 mg dose. Doctors may gradually increase the dosage if needed.
• Maximum Dosage: 6 mg once daily.

Dosage for Depressive Episodes (Depression) in Bipolar I Disorder

• Initial Dosage: The recommended starting dose is between 1.5 mg once daily.
• Maintenance Dosage: On the 15th day of treatment, doctors may increase your dosage to 3 mg once daily. This boost only happens when the doctor feels the need.

Dosage for Schizophrenia

• Usual Dosage: The typical dosage range of Vraylar is between 1.5 to 6 mg once daily.
• Day 1: On the first day of the treatment, you will be prescribed 1.5 mg.
• Day 2: Your dosage will be increased to 3 mg later. Doctors may gradually increase your dosage if needed.
• Maximum Dosage: 6 mg once daily.

Dosage for Major Depressive Disorder (Depression)

• Initial Dosage: The recommended starting dose is between 1.5 mg once daily.
• Maintenance Dosage: On the 15th day of treatment, doctors may increase your dosage to 3 mg once daily. This boost only happens when the doctor feels the need.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

Certain basic administration steps must be followed while taking Vrayler. Doing so will prevent patients from developing serious complications. Here are some of the steps that describe how you can take your medication:

• Read the patient information leaflet (PIL) thoroughly before starting your treatment with Vraylar for schizophrenia management.
• Follow the dosing schedule that is mentioned on your prescription label carefully.
• The medication dosage is based on the condition, tolerability, and other medications you may be using.
• Take the medication by mouth, with or without a meal, once a day, as your doctor prescribes.
• Swallow the capsules as a whole with a glass of water unless instructed otherwise.
• Avoid crushing, breaking, or chewing the capsule particle, as it will release the drug at once.
• You can talk to a medical practitioner if you cannot swallow the capsules. They will surely suggest an alternate treatment or options.
• Ensure you take the capsules with a clean hand to avoid transferring germs.
• Take each medication at the same time regularly for effective results.
• The medication may take a few weeks to show full benefits. Continue using the capsules as directed.
• To decrease the risk of unfavorable side effects, your doctor may suggest you start taking Vraylar at a low dose and gradually increase your dosage.
• Do not discontinue or alter the medication without consulting with your medical practitioner first.
• If your condition does not improve or worsens over time, visit your doctor right away.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

Vraylar is an atypical second-generation antipsychotic drug. While there are no exact details on how Vraylar works, it is thought that this medication rebalances certain chemicals in the brain called neurotransmitters. By adjusting the levels of these neurotransmitters, known as dopamine and serotonin, which are responsible for mood and behavior, Vraylar helps reduce symptoms like hallucinations, delusions, and mood swings in people with schizophrenia and bipolar disorder. This process aids in improving the overall mental health and stability of the patients.

Vraylar can cause certain common and serious side effects, which may temporarily impact the patient’s body and last from a few days to weeks. If any of the below side effects do not go away or cause serious complications, contact your physician as soon as possible.

Common side effects of Vraylar: The side effects given below are usually temporary and commonly occurring. They resolve on their own within a couple of days or weeks without medical intervention. However, if they persist or become bothersome, get in touch with your physician or medical practitioner. Common side effects of Vraylar may include: 

• Involuntary muscle movements: These are also known as extrapyramidal symptoms, including tremors, muscle stiffness, and uncontrollable facial or body movements. Its signs may consist of:
  • Twitching
  • Jerking
  • Twisting movements of the head, neck, tongue, legs, or arms

Healthcare providers might adjust the dosage or prescribe medications like anticholinergics to manage these symptoms. Regular monitoring is crucial for early detection & intervention.

• Difficulty while moving or slower movements: This medication can cause slowed movements and reduced spontaneity, likely linked to dopamine receptors that can impair motor function. To manage this side effect, you may require dosage adjustments and physical therapy to enhance mobility. You should report significant changes in movement to your healthcare provider.
• Muscle stiffness: This can manifest itself as rigidity, which occurs due to the medication’s impact on neurotransmitter pathways that control muscle tone. Patients can engage in stretching exercises and physical therapies. In some cases, additional medications to reduce stiffness may be required. 
• Headache: This is one of the most common side effects associated with the use of Vraylar. This is caused by the changes in neurotransmitter levels in the body caused by the medication. To manage headaches, you should stay adequately hydrated, maintain a regular sleep schedule, and use over-the-counter pain relief medicines. If the headache still persists or becomes worse, talk to your doctor or healthcare provider. 
• Dizziness: This can be due to Vraylar’s effect on blood pressure and central nervous system activity. This usually happens when patients are doing sudden movements, such as standing after sitting or lying for a long time. You should rise slowly from sitting or lying positions over prolonged periods to prevent dizziness. You should ensure you are adequately hydrated and avoid sudden movements to prevent dizziness. If you have severe or persistent dizziness, consult a licensed healthcare professional. 
• Extreme saliva: This medicine can cause increased saliva production, also known as hypersalivation, which may occur due to its impacts on the autonomic nervous system. You should chew sugar-free gum or use saliva-reducing agents to manage this symptom. Excess saliva production can affect the ability to speak or eat properly. If this becomes bothersome, you should seek medical advice. 
• Indigestion: Use of Vraylar can cause gastrointestinal discomfort, including digestion. To prevent this, you should take the medication with food, eat smaller meals, and avoid spicy or greasy foods. You can use over-the-counter antacids to provide relief. But if you experience persistent indigestion, seek medical consultation. 
• Constipation: Due to the anticholinergic properties of Vraylar, some patients may experience constipation while being treated with it. This medication can slow intestinal movement. To help prevent constipation, you should increase dietary fiber intake, stay adequately hydrated, and engage in regular exercise. If necessary, your doctor may recommend you to use a suitable laxative occasionally to avoid dependency. 
• Sudden weight gain: This medication can affect metabolism, causing individuals to eat more. This further leads to weight gain. To prevent weight gain, you should monitor your weight on a regular basis, follow a balanced diet & incorporate physical activity into your daily routines. If you notice significant sudden weight gain, you should discuss it with your doctor. They are most likely to adjust your dosage or suggest you use alternative treatment options. 
• Sleepiness: Sedation or sleepiness is more likely to occur during the initial days of starting treatment with Vraylar. Taking this medication at bedtime may help reduce daytime drowsiness. You should avoid driving, using heavy machinery, or engaging in other hazardous activities until you determine how Vraylar affects your alertness or vision. 
• Akathisia: This involves a feeling of inner restlessness and an urge to move, particularly in the legs, which is associated with Vraylar’s dopaminergic activity. To manage this, you may require Vraylar dosage adjustments or the addition of beta-blockers or benzodiazepines. Early reporting of symptoms to a healthcare provider is important for effective management. 
• Nausea & vomiting: This is a common gastrointestinal side effect associated with the use of Vraylar. This is more likely to occur during the initial days of treatment with this medication. To prevent and manage gastrointestinal discomfort, you should take the medication with food and stay hydrated. If nausea or vomiting persists, consulting a healthcare provider is best recommended. You can take over-the-counter antiemetic medications after discussing with your doctor or healthcare provider.

Serious side effects of Vraylar: While Vraylar for bipolar disorder treatment is an effective treatment option, it can have severe side effects, some of which require immediate medical attention. If you experience any of the side effects given below, you should call your doctor or healthcare provider. Your doctor has prescribed you this medicine after determining that the benefits of Vraylar justify its risks. Severe Vraylar side effects include: 

• Orthostatic hypotension (decline in blood pressure while standing up): The sudden drop in blood pressure can lead to signs such as:
  • Fainting
  • Dizziness
  • Lightheadedness when you stand up too quickly

Vraylar can interfere with the body’s ability to regulate blood pressure. The drug may affect the autonomic nervous system, leading to inadequate constriction of blood vessels upon standing, which results in decreased blood flow to the brain. To prevent and manage this side effect, you should stand up slowly, avoid sudden position changes, and stay well-hydrated. In severe cases, consult a healthcare professional. They may advise you to seek alternative treatment.

• Uncontrolled body temperature. Symptoms are:
  • Hot and dry skin
  • Reduced sweating
  • Heatstroke

• Low White Blood Cell Count (Leukopenia): This medication may reduce white blood cell count, making you more susceptible to infections and causing new or worsening infections. This is more likely to occur in individuals with a history of blood disorders or in those who are already taking medications that suppress the immune system. 
• Sore throat
• Fever
• Mouth ulcers
• Sore mouth and gums

Regular blood tests are important for patients on Vraylar to monitor white blood cell levels, and any signs of infection should be evaluated by a healthcare provider promptly.

• Elevated Blood Glucose Levels: Vraylar can cause an increase in blood glucose levels, particularly in people with type 1 or 2 diabetes or those at risk of developing diabetes. Symptoms of elevated blood glucose include weakness, blurred vision, fruity-smelling breath, excessive thirst and hunger, and frequent urination. If not managed properly, high blood sugar can lead to more severe complications like diabetic ketoacidosis, a medical emergency. To manage this side effect, patients should have their blood glucose levels regularly monitored, particularly if they have a history of diabetes. You should manage your diet, exercise regularly, and adjust other diabetes medications. In some cases, discontinuing Vraylar may be advised if blood glucose levels become uncontrollable.

• High Cholesterol and Triglyceride Levels: Vraylar can increase levels of cholesterol & triglycerides in the bloodstream, which may raise the chance of developing cardiovascular conditions over time. High cholesterol and triglycerides are often silent and may not show symptoms, but they are major risk factors for heart disease and stroke. You should have regular lipid panel tests to monitor cholesterol and triglyceride levels. Lifestyle modifications like adopting a healthy and well-balanced diet, increasing physical activity & managing weight can help alleviate these side effects. In some cases, patients may need medication to control cholesterol levels if they become higher while receiving treatment with Vraylar.
• Seizures: This can occur due to the medication’s effect on brain chemistry, particularly the neurotransmitters dopamine and serotonin. Its signs are:
• Muscle spasms
• Falling
• Confusion

These severe symptoms require prompt medical attention & patients with a history of seizures or other neurological conditions should use Vraylar with caution. To manage this side effect, your doctor may alter the medication dosage or switch to a substitute antipsychotic medication. If you experience symptoms of a seizure, you should avoid engaging in activities that require full attention.

• Allergic Reactions: This medication can cause severe allergies, including anaphylaxis, which can be severe (life-threatening) and include rash, itching, swelling of the face, throat, or tongue, and difficulty breathing. If you experience any of these symptoms, you should seek immediate emergency treatment. To reduce the chance of a hypersensitivity reaction, you should let your doctor or healthcare provider know if you have ever had a hypersensitivity reaction to Vraylar or any of its active or inactive ingredients. See medical attention if you notice any signs and symptoms of a hypersensitivity reaction. In severe cases, patients may need to discontinue the drug and seek alternative treatment. 
• • Tardive dyskinesia: A rare but possible severe side effect of this medication, tardive dyskinesia can cause unusual, uncontrolled movements, especially of the face, mouth, tongue, arms, or legs. If you have such symptoms, you should contact your healthcare provider or doctor immediately.
• Neuroleptic malignant syndrome: This serious condition requires immediate medical attention. If you have symptoms such as a high fever, muscle stiffness or pain, extreme tiredness, confusion, sweating, and an irregular heartbeat, immediately call your doctor or medical professional. In some cases, it may lead to dark urine or signs of kidney problems, such as a decrease in urine output. If you experience any of these signs, seek help right away.
• Hyperglycemia: T​​his medication can increase blood sugar levels, which may worsen or cause diabetes. If you experience symptoms of hyperglycemia (high blood sugar), such as increased thirst or urination, tell your doctor at once. If you have diabetes, it’s essential to monitor your blood sugar at regular intervals, as advised by your healthcare provider. Your doctor may need to adjust your diabetes medications, diet, or exercise routine based on these readings.
• • Dysphagia: Some patients may experience trouble swallowing, leading to aspiration, where food or liquid enters the windpipe. This can potentially cause choking or lung infections like aspiration pneumonia. To manage this side effect, you should seek medical help. Sitting upright and eating slowly can reduce risk, and immediate medical attention is crucial if aspiration occurs.
• Suicidal thoughts and behavior: This is especially noticeable in children, adolescents, and young adults under age 25 using Vraylar. These may arise due to the medication’s effect on brain chemistry, increasing the risk of depression and anxiety. You should carefully monitor yourself and your child for changes in mood or behavior, particularly during the initial weeks of treatment with the medication, and consult a healthcare provider if suicidal thoughts occur. 

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Vraylar may cause adverse reactions or is not an ideal medication for some patients if they have certain medical conditions that affect their health. If you have any of the following factors or conditions, talk to your healthcare provider about your medical history:

• Diabetes: Vraylar may cause high blood glucose levels. So, if you have diabetes and are taking this medication, you are at high risk of worsening your condition. Consult with a medical expert first; they will adjust your diabetes treatment plan accordingly.
• Cholesterol Problems: This medication can also affect the patient’s cholesterol and triglyceride levels, and taking Vraylar with active cholesterol problems can exacerbate the condition. If you have such a condition during your treatment with Vraylar, your doctor may change your cholesterol treatment plan.
• Seizures: This drug can increase the chances of seizures, specifically in patients with a history of seizures. If you have this medical condition, talk to a medical professional and discuss every risk and benefit associated with it.
• Older Patients: If you are 65 years of age or older, you are likely to experience certain side effects from this medication, such as dizziness, falls, heatstroke, and movement problems. For such patients, doctors may likely give a lower dose of Vraylar and will monitor closely for any side effects during the treatment.
• Severe Kidney or Liver Problems: This medication is not known to be safe for use in people with severe kidney or liver problems. To avoid any risk, talk to your healthcare provider for expert guidance.
• Low White Blood Cell Levels: Vraylar may result in low white blood cell levels in the patient’s body. If you have had low white blood cell counts in the past, consult with a medical professional before starting your treatment with this medication. Your healthcare expert will order a blood test to determine whether its usage is safe or not.
• Stroke or Heart Disease: Antipsychotic medication, including Vraylar, can reduce blood pressure while standing or sitting up. If you have any heart problems or have ever had a stroke, taking this medication may worsen your condition. Seek medical assistance to ensure that the product is safe for you.
• High/Low Blood Pressure: Medications like Vraylar may alter blood pressure levels. Any sudden change in blood pressure may develop or exacerbate your medical condition. If you have blood pressure issues, consult with a medical professional.
• Allergic Reaction: If you have allergies or are allergic to any of the medication’s ingredients, your practitioner will not recommend this medication. 

FDA Boxed Warning

This medication has received boxed warnings from the FDA. These warnings are said to be the most serious warnings that the authority has issued. It aims to alert doctors and patients about the harmful effects of the drug that can be life-threatening. These warnings are:

• Risk of Death in Older Patients With Psychosis Due to Dementia: Patients in the age group of 65 and above having dementia are most likely to develop psychosis or loss of contact with reality. In some cases, if such patients are taking antipsychotic medications like Vraylar, they have a higher risk of death. So, the FDA has not approved this medication for senior patients who have psychosis associated with dementia.
• Suicidal Thoughts and Behaviors: In some cases, Vraylar can increase the chances of developing suicidal thoughts and behaviors in children and adults below 25 years. This medication belongs to the antipsychotic class of drugs but also has an antidepressant effect. Patients taking this drug will be monitored closely by a medical professional for any signs of suicidal thoughts and behaviors. Due to this reason, Vraylar is not approved for children younger than 17 years.

It is important for patients to discuss every risk and benefit with their healthcare provider before starting treatment with Vraylar. So, here are certain precautions that people can take to avoid any serious complications in the future:

• Antipsychotic medications like Vraylar may make you sweat less, increasing your chance of getting heatstroke. So, to avoid such situations, do nothing that can cause you to overheat. This may include hard work or intense workout sessions, especially in hot weather. Also, avoid using hot tubs. Moreover, drink lots of fluids in hot weather and wear light clothes. However, if you develop a persistent fever, headache, dizziness, or mood changes, get medical help immediately.
• If you are undergoing surgery or any medical procedure, inform your medical practitioner or dentist about the product you use. This includes prescription drugs, nonprescription drugs, and herbal products.
• Vraylar can be only used in pregnant women when clearly needed; otherwise, doctors may likely recommend against this medication as it may harm the baby. Moreover, if you have used this drug during the last three months of pregnancy, your child may develop symptoms such as muscle stiffness, feeding or breathing difficulties, constant crying, or drowsiness. Parents need to be aware of such signs, and if they notice these sudden changes during the first month of the baby, inform the doctor right away.
• Do not abruptly discontinue using Vraylar, as mental or mood disorders like bipolar disorder, schizophrenia, etc, are serious problems that can cause adverse side effects if left untreated. If you become pregnant or planning to have a baby, talk to your medical practitioner first and then make any decision regarding discontinuing the medication.
• It is unknown whether the drug passes into the breast milk of a nursing mother or not. So, lactating mothers are advised to consult with an expert before deciding.

Vraylar is contraindicated in patients who have hypersensitivity or a history of allergic reactions to Cariprazine. The product may contain certain inactive components, causing adverse effects in patients, which can be life-threatening. These reactions include:

• Pruritus
• Rash
• Urticaria
• Angioedema, like swelling on the face, tongue, lip, and pharyngeal edema

Patients are strictly advised not to miss any of their doses, but if someone has skipped a dose of their medication, they can take the following actions:

• Take the missed dose as soon as possible or whenever you remember.
• If it is almost time for the next dose, you can skip the last missed dose and continue following your usual dosing schedule.
• Remember not to take double or extra doses to compensate for the missed dose. This can lead to adverse reactions, which can be life-threatening.
• Use medication apps and pill organizers or set reminders on your phone to avoid skipping any of your doses.
• If you still have unsolved queries or concerns, talk to a medical professional and seek expert guidance.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

Patients are usually advised not to take exceeding amounts of maximum daily dose unless a doctor has prescribed it. However, if someone has overdosed on Vraylar and is experiencing any unusual symptoms like fainting or trouble breathing, they should immediately visit the nearest clinic or get medical help by calling 911. Overlooking such signs can result in serious complications, which can be life-threatening.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

• Store the capsules at room temperature of 20–25°C.
• Make sure that the capsules are in a tightly locked container.
• Keep the medication somewhere safe and away from the reach of children and pets.
• Avoid storing the medication in damp areas like the bathroom or near the sink.
• Do not flush the medication down the toilet.
• Throw the medication appropriately when not in use or when it reaches its expiration date.
• Take expert advice from a professional practitioner or pharmacist on discarding the product without harming the environment.
• Read the product’s label for complete storage instructions.
• Do not keep the medication under direct sunlight.
• Keep it away from heat or moisture.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Vraylar can interact with several medications and supplements that cause adverse reactions. Different interactions may have different effects on the patient’s body. While some interactions can disturb the drug’s functioning, others can raise their side effects or may exacerbate them. Below are some of the drugs that can interact with Vraylar:

• Amprenavir
• Belzutifan
• Carbamazepine
• Dabrafenib
• Etravirine
• Fentanyl
• Hydromorphone
• Itraconazole
• Ketoconazole
• Levorphanol
• Metoclopramide
• Nefazodone
• Oxycodone
• Primidone
• Rifampin
• Sodium oxybate
• Telaprevir
• Voriconazole
• Zonisamide

What Are the Other Vraylar Interactions?

Other than the above medications, Vraylar may have certain alcohol, food, lifestyle, and disease interactions, which are as follows:

• Ethanol
• Grapefruit juice
• Suicidality
• Dementia
• NMS
• Aspiration
• Seizure
• Hematologic abnormalities
• Hyperglycemia/diabetes
• Hypotension
• Lipid alterations
• Renal impairment
• Weight gain
• Hyperprolactinemia
• Tardive dyskinesia

[Note: This isn’t a complete list, and there could be other drugs that interact with Vraylar. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Certain patients can not use Vraylar due to various factors, including other medical conditions, allergic reactions, or anything else. As a result, doctors suggest alternative treatments or medications to such patients. These alternative medications are:

• Divalproex
• Atypical antipsychotics, like:
  • Aripiprazole
  • Asenapine
  • Olanzapine
  • Quetiapine
  • Risperidone
  • Ziprasidone
• Typical (first-generation) antipsychotics, including:
  • Chlorpromazine
• Lamotrigine
• SSRI antidepressants, such as:
  • Fluoxetine/olanzapine
  • Zyprexa
  • Zyprexa Zydis
• Other atypical antipsychotics, such as:
  • Lurasidone
  • Quetiapine
• Brexpiprazole
• Lithium
• Caplyta

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

It is important to note that the cost of Vraylar is not the same everywhere. The actual price of this medication depends on various factors, such as your insurance plan, location, and the pharmacies you use. Vraylar, with its effective therapeutic quality, can be expensive for some individuals. Here, insurance coverage plays a significant role. With insurance, you can buy affordable Vraylar capsules at a discounted price. However, not all medications are covered under insurance. To manage these costs, turn out to pharmacies like Polar Bear Meds, where you can buy Vraylar online from Canada at affordable rates. Moreover, first-time buyers can use the Vraylar coupon code WELCOMEPB10 to receive a 10% discount on their first order.

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