SAVE $20 OFF First Orders with Coupon Code: POLARBEARN20

🚨IMPORTANT: Zepbound is temporarily out of stock. Mounjaro can be used as an alternative to it, as they both contain the same active ingredient, Tirzepatide. 

Buy Zepbound Online from Canada for weight loss



Zepbound is a prescription drug approved by the FDA for weight loss and long-term weight management in adults. It comes in a one-time-use injectable pen for subcutaneous administration and is available in six strengths. Zepbound works by targeting two specific hormone receptors, GIP and GLP-1, which manage insulin use and fat metabolism. The typical starting dosage is 2.5 mg once per week, with potential increases based on doctor recommendations. Side effects can include injection site reactions, nausea, and more severe effects like pancreatitis. It’s important to discuss your health history with your doctor before starting Zepbound, especially if you have type 2 diabetes, kidney problems, or a history of pancreatitis. The drug has a boxed warning about a possible risk of thyroid cancer. Zepbound should be used alongside diet and exercise changes for effective weight management.

Product Overview

Zepbound is a prescription medication primarily used for weight loss and long-term weight management in adults. Zepbound, with its active ingredient, Tirzepatide, is used for chronic weight management in adults. It is indicated for use in adults with obesity or overweight and other weight-related conditions such as type 2 diabetes, high blood pressure or high cholesterol. This medication should be used alongside a reduced-calorie diet and increased physical activity. Zepbound works by targeting two hormone receptors, GIP and GLP-1, which are involved in insulin regulation and fat metabolism. By mimicking the effects of these hormones, Zepbound improves insulin secretion, slows down food digestion, and helps people feel full longer, aiding in weight loss and management.

The typical starting dosage for weight management is 2.5 mg once per week, possibly increasing the dose every four weeks based on the patient’s response and doctor’s recommendation. The maximum recommended dosage is 15 mg once per week. Common side effects of Zepbound include injection site reactions, nausea, fatigue, and digestive issues such as constipation or diarrhea. More severe side effects, though rare, can consist of pancreatitis, kidney problems, and severe allergic reactions. Patients with a history of type 2 diabetes and diabetic retinopathy, kidney issues, or pancreatitis should discuss these conditions with their doctor before starting Zepbound.

Zepbound carries a boxed warning regarding a potential risk of thyroid cancer based on animal studies. Patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 should not use Zepbound. Patients are advised to follow their doctor’s instructions carefully when administering Zepbound and promptly report any side effects or concerns. The medication should be stored in the refrigerator, and patients should ensure proper disposal of used pens. It’s important to note that Zepbound is intended for long-term use and should be part of a comprehensive weight management program that includes dietary changes and exercise. Patients should have regular check-ups with their healthcare provider to monitor their progress and adjust the treatment plan as needed.

Uses of Zepbound

Zepbound is used in adults for:

  • Weight loss
  • Long-term weight management

How to Use Zepbound?


This medication is provided as a single-use injectable pen for injection under the skin (subcutaneous administration). It comes in six different strengths:

  • 2.5 mg per 0.5 ml
  • 5 mg/0.5 ml
  • 7.5 mg/0.5 ml
  • 10 mg/0.5 ml
  • 12.5 mg/0.5 ml
  • 15 mg/0.5 ml

The availability of various dosages allows patients to receive the precise amount of medication required for their specific health condition.

Recommended Dosage for Patients

Dosage for Weight Loss and Its Management

  • Starting Dosage: When prescribed for weight management, Zepbound typically starts at a dosage of 2.5 mg. This dosage is administered via injection under the skin once a week for four weeks.
  • Dosage Adjustments: After the initial four weeks, your doctor may suggest increasing the dosage to 5 mg once a week. Subsequent increases may be made by 2.5 mg every four weeks based on your response to the medication.
  • Typical Recommended Dosages: Common dosages for weight management are 5 mg, 10 mg, or 15 mg once a week. The maximum recommended dosage is 15 mg once a week. For personalized dosage information, it’s important to consult with your healthcare provider.

Long-term Treatment

  • Zepbound is designed for long-term use. If your doctor finds that Zepbound is effective and safe for your condition, you will likely continue using it for an extended period.
  • Before starting Zepbound, your doctor will have a detailed discussion with you about your treatment plan. This will help ensure that the medication is suitable for your specific needs.

[Note: Remember these recommendations may vary depending on person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Take It?

Your doctor will begin with a low dosage and adjust it gradually to find the right amount for you. They aim to prescribe the lowest dosage that still gives you the desired effect. Zepbound should be used in conjunction with dietary changes and exercise for effective weight management. Here’s how to take Zepbound:

  • Zepbound is available as a solution in a single-dose prefilled pen.
  • It is administered as a subcutaneous injection, which means you’ll inject it just under your skin.
  • Your doctor or a healthcare professional will teach you or a caregiver how to give yourself the injection.
  • Follow your doctor’s instructions carefully when injecting Zepbound.

Here are some instructions for where to Inject Zepbound:

  • You can inject Zepbound into your stomach, thigh, or upper arm once a week.
  • If injecting into your stomach, avoid areas within 2 inches of your belly button.
  • Choose a different site for each injection and avoid areas where your skin is tender, rigid, or irritated to reduce the risk of side effects like bleeding or pain.
  • You can take your Zepbound injection with or without food.

Remember, following your doctor’s instructions and dosage recommendations for Zepbound is essential.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Zepbound Work?

Zepbound works by targeting two specific hormone receptors in our body: GIP and GLP-1. These receptors manage our body’s use of insulin and how it processes both sugar and fats. Basically, GIP and GLP-1 are hormones produced in the intestine, and they become active when we eat. 

Tirzepatide mimics the natural effects of GIP while also interacting with the GLP-1 receptor. This dual action helps improve insulin secretion, which is essential for controlling blood sugar levels and aids in regulating fat metabolism. Additionally, these hormones help in slowing down the process of food leaving the stomach, which means people feel full for a longer time. This can be especially beneficial for those dealing with chronic obesity, as it supports weight loss by reducing the urge to eat more frequently.

Important Safety Information

Side Effects

These are the most common side effects of Zepbound that may include:

  • Fatigue
  • Diarrhea or constipation
  • Abdominal pain
  • Indigestion or gastroesophageal reflux disease (GERD)
  • Burping
  • Low blood pressure
  • Mild allergic reaction
  • Hair loss
  • Mildly increased heart rate
  • Injection site reactions (like bruising, pain or itching around the injection area)
  • Vomiting or nausea

The majority of these side effects might resolve within a few days to a couple of weeks. But, if they intensify or persist, it is advisable to consult with your doctor or pharmacist. These are the serious side effects of Zepbound that include:

  • Changes in vision in patients with type 2 diabetes
  • Gallbladder problems (such as gallstones)
  • Inflammation of the pancreas (pancreatitis)
  • Low blood sugar (hypoglycemia)
  • Kidney problems (kidney failure)
  • Depression or thoughts of suicide
  • Severe stomach problems (including nausea, vomiting, or severe diarrhea)

Some individuals might experience an allergic reaction to the medication Zepbound. Mild allergic reactions may include:

  • A skin rash
  • Itchiness
  • Flushing (a temporary warmth, redness, or deepening of skin color)

Although rare, more severe reactions can occur. These might include 

  • Swelling under the skin (in areas like the eyelids, hands, lips, or feet)
  • Leading to difficulty in breathing
  • Swelling of the mouth, tongue, or throat

If you suspect you’re having an allergic reaction to Zepbound, it’s important to seek medical attention immediately.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]


Before starting Zepbound, it’s important to discuss your medical history with your doctor. Zepbound might not be suitable for you if you have certain health conditions or other factors that could affect your well-being.

  • Type 2 diabetes and diabetic retinopathy: If you have type 2 diabetes and diabetic retinopathy, it’s essential to talk to your doctor before starting treatment with Zepbound. This medication may cause temporary changes in your vision. Your doctor can help you decide if Zepbound is a safe option for your specific health needs.
  • Kidney problems: If you have kidney issues, it’s important to talk to your doctor before using Zepbound. This medication might cause severe digestive issues that can lead to dehydration, which can make kidney conditions worse. Your healthcare provider can help you decide if Zepbound is a suitable treatment option for you based on your kidney health.
  • Digestive system problems: This drug might cause serious issues with your digestive system. This could be a problem for people who already have issues with their digestive system, like stomach paralysis. If you have any digestive problems, you should talk to your doctor before taking Zepbound. Your doctor can help you decide if this medication is safe for you to use.
  • Pancreatitis: This medication might cause pancreatitis, which is inflammation of the pancreas, as a side effect. It’s not entirely clear if Zepbound is safe for people who have had pancreatitis before. If you have a history of this condition, it’s crucial to discuss it with your healthcare provider before starting Zepbound. They will help determine if this medication is suitable for you. 
  • Mood conditions, including depression: Zepbound for weight loss can sometimes lead to thoughts of suicide or suicidal behaviors. This risk might be higher in people who have mood disorders, such as depression. If you’re considering Zepbound, it’s essential to discuss with your doctor whether this medication is suitable for you, taking into account your mental health history.
  • Allergic reaction: If you’ve previously had an allergic reaction to Zepbound or any of its components, your doctor will likely advise against prescribing it again to avoid another allergic reaction. It’s important to discuss alternative treatment options with your healthcare provider that may be more suitable for you. 

Boxed Warning

Zepbound has a special warning called a boxed warning, which is the highest level of warning given by the FDA. This warning is about a possible risk of thyroid cancer associated with the medication.

The main ingredient in Zepbound, called tirzepatide, has been shown to cause thyroid tumors in animal studies. It’s not clear if it can cause thyroid cancer in humans, but because of the potential risk, your doctor might not prescribe Zepbound if:

  • You or a family member has had a type of thyroid cancer called medullary thyroid cancer.
  • You have a condition called multiple endocrine neoplasia type 2, which increases the risk of thyroid cancer.

If you’re taking Zepbound, watch for symptoms of thyroid cancer and tell your doctor if you notice:

  • A persistent, hoarse voice
  • A lump in your neck
  • Difficulty swallowing
  • Difficulty breathing

If you have any concerns about this warning or the medication, it’s crucial to discuss them with your doctor.


  • Breastfeeding: The safety of using Zepbound while breastfeeding is unclear. There is insufficient data to confirm if the medication can transfer into breast milk or how it might affect a breastfeeding infant. If you are currently breastfeeding or plan to do so, it’s essential to discuss this with your healthcare provider before starting Zepbound. Your doctor can help you explore other treatment options and provide guidance on how to feed your baby safely.
  • Pregnancy: The safety of Zepbound during pregnancy has not been fully established through clinical trials. Although animal studies have shown the potential for congenital disabilities, it’s crucial to remember that these findings might not directly apply to humans. If you are pregnant or considering pregnancy, it’s essential to inform your healthcare provider before beginning Zepbound treatment. Your doctor can offer advice on the most appropriate treatment plan for your situation.


  • Medullary thyroid CA family hx
  • Medullary thyroid CA hx
  • Multiple endocrine neoplasia syndrome type 2
  • Suicidality hx
  • Suicidal ideation
  • Hypersensitivity to drug or ingredient

Missed Dose

  • If you miss a dose of Zepbound, take it as soon as you remember, but only if it’s within four days (96 hours) of the missed dose.
  • If more than four days have passed since the missed dose, skip it and continue with your regular dosing schedule.
  • Never take two doses at once to compensate for a missed dose.
  • Use a medication reminder to help you stay on track with your doses. This could be an alarm, a note in a visible place, or a reminder app on your phone.
  • If you’re unsure about how to handle a missed dose, consult your doctor or pharmacist for guidance.

[Note: If you have missed a dose of your medication and are still determining when to take the next one, immediately consult your doctor or pharmacist.]


  • It is essential not to use more Zepbound than your doctor has prescribed. Taking more than the recommended dose of some medications can lead to harmful effects or an overdose.
  • If you accidentally take more Zepbound than advised, contact your doctor immediately.
  • In case of severe symptoms, call 911 or your local emergency number, or go to the nearest emergency room without delay.

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]


  • Keep unopened Zepbound pens in the fridge between 36°F and 46°F (2°C and 8°C).
  • Store the pens in their original box to protect them from light.
  • Sometimes, you might need to store Zepbound at room temperature, like when traveling. In such cases, you can keep the Zepbound pen at temperatures up to 86°F (30°C) for up to 21 days.
  • Don’t put the pen back in the fridge after storing it at room temperature. If it’s been at room temperature for 21 days and you haven’t used it, you should throw it away.
  • Don’t freeze the pens. If a pen gets frozen, you should throw it away and get a new one.
  • Always check the pen for any damage before using it. Don’t use a damaged pen.
  • Make sure the pens are clearly labeled to avoid mixing them up with other medicines.
  • Keep the pens out of reach of children to prevent any accidents.
  • By following these storage tips, you can ensure that Zepbound stays effective and safe for use.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Zepbound Interactions

When you take Zepbound, it’s essential to know that it can interact with other medications, certain foods, and supplements. These interactions can change how Zepbound works in your body. Before you start using Zepbound, consult with your doctor and pharmacist. Make sure to tell them about all the medicines you’re currently taking, whether they’re prescribed by a doctor or bought over the counter. 

Don’t forget to mention any vitamins, herbs, or supplements you’re using too. Sharing this information can help prevent any unwanted interactions. If you’re unsure how other drugs might interact with Zepbound, don’t hesitate to ask your doctor or pharmacist for advice. Zepbound can interact with a variety of medications and some supplements and foods as well.

  • Drug interactions: Zepbound is a medication that slows down your digestion, which means it can change how other medications are absorbed into your body. Here are some medicines that might interact with Zepbound:
    • Birth Control Pills: Medications like ethinyl estradiol/norethindrone (found in Junel and similar products) and ethinyl estradiol/drospirenone (found in Yaz and similar products).
    • Insulins: Medications like insulin lispro (found in Humalog and similar products) and insulin glargine (found in Lantus and similar products).
    • Sulfonylureas: Medications like glipizide (found in Glucotrol XL), glimepiride (found in Amaryl) and Warfarin (found in Jantoven).
  • Alcohol: There are no known interactions between alcohol and Zepbound, so it’s generally considered safe to drink alcohol while on this treatment. However, it’s always a good idea to consult your doctor or pharmacist about how much alcohol is safe for you to consume while taking Zepbound.
  • Pregnancy and Breastfeeding: Zepbound is not recommended for use during pregnancy, as losing weight while pregnant could harm the unborn baby. If you become pregnant while taking Zepbound, you should stop using it immediately and inform your doctor. You may also be asked to join a pregnancy registry that collects information about the drug’s safety during pregnancy. It is currently unclear if Zepbound is safe to use while breastfeeding. If you are pregnant, breastfeeding, or planning to become pregnant or breastfeeding, discuss with your doctor before starting Zepbound treatment.
  • Birth control: If you can become pregnant, your doctor might suggest using birth control while you’re on Zepbound. However, Zepbound can reduce the effectiveness of birth control pills. As a result, your doctor may advise you to use a different or additional form of birth control for the first four weeks of Zepbound treatment and for four weeks after any increase in your dosage.

[Note: This isn’t a complete list, and there could be other drugs that interact with Zepbound. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Zepbound Alternatives

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Quick Tips

  1. Is Zepbound a new weight loss version of Mounjaro?
  2. Why is Zepbound the ultimate match for obesity?

Frequently Asked Questions

Are Zepbound and Mounjaro the same thing?

Both medications contain tirzepatide as their main ingredient, but they are prescribed for different health conditions. Mounjaro is specifically designed for individuals with type 2 diabetes. At the same time, Zepbound is intended for adults who are significantly overweight, as indicated by their Body Mass Index (BMI), or those who have weight-related health issues. It’s important to consult with a healthcare professional to determine which medication is suitable for your specific health needs.

Is Zepbound safe for older adults?

This medication is generally considered safe for older adults, including those aged 65 and over. Research has shown that the side effects experienced by older adults are similar to those of younger individuals. However, it’s important to note that older adults are likelier to be on other medications that might interact with Zepbound. They are also more prone to certain health conditions, such as kidney issues, which could make Zepbound less suitable for them. If you’re an older adult and have concerns about the safety of Zepbound for your specific situation, it’s crucial to discuss this with your doctor. They can provide guidance tailored to your health needs and medication profile. 

What is the best time to take Zepbound?

Zepbound is a medication that you take once a week with an injection. You can choose any time of day to take it, but it’s important to stick to the same day every week. You can inject it into your stomach area, thigh, or upper arm. When starting Zepbound, pick a day of the week that fits well with your schedule. It’s also a good idea to talk to your healthcare provider about the best way to use Zepbound for your specific situation.

What is the difference between Zepbound and Ozempic?

Zepbound and Ozempic both target GLP-1 receptors, affecting appetite and blood sugar. However, Zepbound also activates GIP receptors in the stomach and brain. Both GIP and GLP-1 help control blood sugar by enhancing insulin response. This dual action of Zepbound may offer a different approach to managing blood sugar levels compared to Ozempic.

Our Guarantee

At, we assure you the most affordable price to buy Zepbound from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently access Zepbound prescription online at a substantial cost, call us at 1-888-779-2193 toll-free.


All orders are shipped via XPRESS POST arriving between 3-5 business days.
(Shipping times may vary based on time of year)

Shipping prices:
Refrigerated items $29.99
Non-refrigerated items $19.99

Questions? Watch our shipping video here!

Shipping costs will be added at checkout.



Rated 5.0 out of 5
5.0 out of 5 stars (based on 360 reviews)
Very good1%

Thank you very much for your help

Rated 5.0 out of 5
August 11, 2022

The customer service is outstanding. I appreciate it.


Thanks so much!

Rated 5.0 out of 5
August 10, 2022

You all have been amazing and I’m so glad I found you

I love doing business with our Canadian


So Easy to order

Rated 5.0 out of 5
July 27, 2022

It is very easy to order with them. The prices are great and the shipping is so quick. Highly Recommend them!


Best Service EVER!

Rated 5.0 out of 5
July 26, 2022

Anytime I call and need help, they are always there and help me in every way possible. I love working with them. Best service ever!


My first order with a Canadian pharmacy

Rated 5.0 out of 5
July 15, 2022

First time ordering from this pharmacy. The entire process was so easy and the questions I did have the customer service representative was very helpful and knew what he was talking about. I felt so good having found them

Scroll to Top