Tirzepatide

Mounjaro Pen

Mounjaro is a medicine prescribed by your doctor to help control blood sugar in adults with type 2 diabetes. This FDA-approved medication contains tirzepatide as an active ingredient and works alongside proper diet and exercise. Mounjaro helps your body by activating certain receptors called GIP and GLP-1. This helps your body release insulin better in the first and second phases and lowers glucagon levels. The Pen has strengths ranging from 2.5 mg to 15 mg per 0.5 mL injection. It’s important to note that Mounjaro is unsuitable for people with type 1 diabetes. However, you can only buy Mounjaro from Canada with your doctor’s prescription.

Product Overview

The Mounjaro (tirzepatide) is an FDA-approved medication to lower A1C levels and enhance insulin response. However, it also assists you in weight management but is not FDA-approved for such purposes. Dosage starts at 2.5 mg/week, increasing gradually to 15 mg/week. The injection is administered in the belly or thigh, with precautions to avoid specific areas. Mounjaro mimics GLP-1 and GIP actions, regulating blood sugar levels. Common side effects include nausea, vomiting, decreased appetite, and serious effects like pancreatitis or hypoglycemia.

A boxed warning highlights potential thyroid cancer risks. Precautions involve discussing medical history, especially pancreatitis, kidney problems, and diabetic retinopathy. Additionally, Mounjaro may interact with insulin, sulfonylureas, glinides, and birth control pills. However, herb and vitamin interactions are uncertain, and there are no reported interactions with food, vaccines, or lab tests.

Moreover, instructions vary based on the time since the last dose if a dose is missed. However, taking more Mounjaro injections can lead to hypoglycemia or pancreatitis, necessitating medical attention. Mounjaro alternatives like Ozempic, Repaglinide, and others are available, but using them should be approved by a doctor. Always follow professional advice and refrain from self-medicating.

Uses of Mounjaro Pen

Mounjaro is used for the following purposes:

• It lowers A1C levels in the blood.
• Activates GIP & GLP-1 receptors.
• Mounjaro enhances the body’s response to insulin. 
• Although not FDA-approved for weight loss, Mounjaro can reduce food intake and slow down stomach emptying, potentially aiding in weight management.

How to Use a Mounjaro Pen?

Dosage

Mounjaro comes in injectable form and has the following 6 strengths:

• Mounjaro 2.5 mg Pen
• Mounjaro 5 mg Pen
• Mounjaro 7.5 mg Pen
• Mounjaro 10 mg Pen
• Mounjaro 12.5 mg Pen
• Mounjaro 15 mg Pen

Recommended Dosage for Mounjaro

Starting Dose (Weeks 1 to 4): 2.5 mg subcutaneously once a week & on the same day.
Maintenance Dose (Weeks 5 to 8): Your doctor may prescribe you to increase the dosage to 5 mg once a week.
Maintenance Dose (7.5 mg, 10 mg): From week 9 and on, your healthcare provider may increase the dose by 2.5 mg after you have been using the current dose for at least 4 weeks. This is done to determine if additional glycemic control is needed.
Maintenance Dose: Move to 12.5 mg for greater sugar control (if your doctor prescribed).
Maximum Dose: The highest recommended Mounjaro dose is 15 mg once a week.

[Note: If your doctor recommends a dosage adjustment for Mounjaro, feel free to discuss it with them. Schedule a consultation with your doctor today!]

How to Take Mounjaro?

• • Mounjaro Pen is used in doses ranging from 2.5 mg to 15 mg.
  • Your doctor prescribes doses that depend on the following:
    • The type & severity of the condition you are using the medication to treat
    • Your age
    • Other drugs you are taking to lower your blood sugar levels
    • Other conditions you may have
  • Choose a clean and dry spot on your belly or your thigh for the injection.
  • If someone is assisting you in taking the injection, they can inject in your upper arm. Avoid areas with broken, discolored, or hard skin.
  • Make sure the Mounjaro Pen is locked before use.
  • Remove the gray base cap and position the bottom of the pen flat against your skin.
  • Unlock the pen and press and hold the purple injection button for about 10 seconds.
  • Listen for two clicks – the first indicates the start of the injection, and the second signals the end.
  • Dispose of the used Mounjaro Pen in a sharps disposal container, which is a sturdy plastic container designed for sharp objects.
  • Don’t inject Mounjaro in the same spot. If you have a preferred area, pick a different spot in that area for each injection.

[Important Tip: The provided information is not exhaustive guidance on Mounjaro usage. Before starting Mounjaro, it is essential that your healthcare provider demonstrates proper Pen usage. Please consult with them for detailed instructions!]

How Does Mounjaro Work?

Mounjaro (tirzepatide) functions as a receptor agonist for GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). This medication mimics the actions of GLP-1 and GIP, which are hormones naturally released by the gut post-meal ingestion. The primary purpose of these hormones is to regulate blood sugar levels. They prompt the body to increase insulin release, reduce sugar release, and slow down the process of digestion. These coordinated actions collectively contribute to the reduction of blood sugar levels. Mounjaro (tirzepatide) intervenes by emulating the functions of GLP-1 and GIP, thereby aiding in controlling blood sugar levels.

Important Safety Information

Side Effects

Common side effects of Mounjaro include:

• Nausea
• Vomiting
• Decreased Appetite
• Constipation
• Diarrhea
• Stomach Pain
• Tiredness
• Indigestion

Mild side effects of Mounjaro include:

• Dizziness
• Facial Changes
• Fatigue
• Acid Reflux
• Injection Site Reactions
• Hair Loss
• Rise in Heart Rate

Serious side effects of Mounjaro include:

• Acute Pancreatitis 
• Hypoglycemia 
• Kidney Damage
• Allergic Reaction
• Risk of Thyroid Cancer
• Acute Gallbladder Disease

Warnings

Boxed Warning

This medication carries a boxed warning, the most serious caution issued by the Food and Drug Administration (FDA) to alert both doctors and patients about the potentially hazardous effects of the drug. In studies with rats, tirzepatide, the active ingredient in Mounjaro, demonstrated a tendency to induce thyroid cancer, specifically C-cell tumors in the thyroid. It remains uncertain whether Mounjaro might lead to thyroid cancer, such as MTC (Medullary Thyroid Carcinoma), in humans.

Notably, no instances of thyroid cancer were reported among individuals participating in clinical trials with this medication. Due to this potential risk, doctors typically refrain from prescribing Mounjaro if a patient or their family member has a history of MTC or a condition known as MEN 2, an abbreviation for multiple endocrine neoplasia syndrome type 2, which is a genetic condition associated with the risk of thyroid cancer.

If you undergo Mounjaro treatment, promptly inform your doctor if you experience symptoms indicative of thyroid tumors, such as a neck mass or lump, painful swallowing, breathing difficulties, or persistent hoarseness. In the presence of these symptoms, your doctor is likely to suspend your Mounjaro treatment temporarily. If thyroid cancer is confirmed, discontinuation of the drug is typically recommended.

Note: [If you have any questions or concerns regarding the potential risk of thyroid cancer associated with Mounjaro, it is advisable to discuss them with your doctor.]

Precautions

Before starting Mounjaro treatment, it is essential to discuss your medical history with your healthcare provider. The suitability of the medication may be influenced by specific medical conditions or other factors affecting your well-being. These may include

Pancreatitis: It is unclear whether Mounjaro is safe for individuals with a history of pancreatitis (inflammation of the pancreas). Past occurrences of this condition may heighten the risk of developing pancreatitis as a potential side effect of Mounjaro. In such cases, your doctor may explore alternative treatment options.

Kidney Problems: Severe vomiting and diarrhea associated with Mounjaro use could lead to dehydration, potentially resulting in kidney problems. If you already have existing kidney issues and your doctor prescribes Mounjaro, close monitoring of your kidney function may be necessary.

Diabetic Retinopathy: Mounjaro may temporarily exacerbate diabetic retinopathy, a vision problem. Individuals with this condition should communicate with their doctor, who may recommend vigilant observation for changes in vision, such as blurred vision. If diabetic retinopathy does not improve over time, a visit to an ophthalmologist may be advised.

Digestive System Problems: The safety of Mounjaro for individuals with digestive system problems, like gastroparesis, is uncertain. The presence of such conditions may elevate the risk of severe digestive problems as a side effect of Mounjaro. Your doctor might explore alternative treatment options in such cases.

Allergic Reaction: If you have experienced an allergic reaction to Mounjaro or its ingredients in the past, your doctor is likely to avoid prescribing Mounjaro. It is advisable to consult with your doctor regarding alternative medications that may be more suitable for you.

Other Important Precautions

Pregnancy and Mounjaro: If you’re pregnant, your doctor may advise against using Mounjaro because it’s unclear if it’s safe during pregnancy. The drug was not tested on pregnant people during clinical trials, and studies on animals suggest that the active ingredient, tirzepatide, could potentially harm a fetus. If you’re expecting or planning to become pregnant, it’s important to discuss alternative ways to manage diabetes with your doctor.

Fertility and Mounjaro: It’s uncertain whether Mounjaro affects fertility (the ability to get pregnant or impregnate someone). Animal studies showed that male animals given tirzepatide did not have fertility issues. However, some female animals showed reduced fertility, possibly linked to decreased food intake and body weight. Keep in mind that findings in animals may not directly apply to humans. If you have concerns about Mounjaro and fertility, consult your doctor.

Birth Control and Mounjaro: It’s essential to know that Mounjaro might interact with certain birth control pills, potentially reducing their effectiveness during the first 4 weeks of treatment and 4 weeks after each dose increase. If you take oral hormonal birth control, your doctor may suggest switching to a non-oral method (like the patch or vaginal ring) or adding a barrier method (like condoms). You may be able to go back to your birth control pill after 4 weeks from the last dose increase. For more details, consult your doctor or pharmacist.

Breastfeeding and Mounjaro: Using Mounjaro while breastfeeding is not recommended, as its safety during this period is uncertain. Researchers have not studied its effects on breast milk. If you’re breastfeeding or planning to, discuss the situation with your doctor before starting Mounjaro. They can suggest safe ways to manage diabetes while considering your breastfeeding needs.

Missed Dose

If you forgot to take Mounjaro and it’s within 4 days of your last dose:

• Inject the missed dose as soon as you remember.
• Continue with your regular injection schedule on the usual day.

If it’s been more than 4 days since your last dose,

• Wait until your normal injection day to take the missed dose.
• Avoid taking two doses within 3 days.

If you miss more than one Mounjaro dose in a row:

• Contact your healthcare provider for guidance.
• You might need to temporarily reduce your dosage before returning to the regular amount.

Note: [Please consult your healthcare provider about your Mounjaro missed dose & take it as soon as possible!]

Overdose 

Taking more Mounjaro than recommended can lead to an overdose and increase the risk of side effects. The most common side effects of an overdose include nausea and diarrhea. However, stomach pain, vomiting, and heartburn may also occur.

Note: [If you suspect that you or someone you know has taken too much Mounjaro, it’s crucial to contact your healthcare provider for guidance, even if there are no apparent side effects. Alternatively, you can contact Poison Control at 1-800-222-1222 for assistance.]

Storage

• It’s best to keep Mounjaro in the fridge between 36⁰F to 46⁰F and in its original box to shield it from light. 
• If you don’t have a fridge, you can store it at room temperature (up to 86⁰F) for up to 21 days. 
• For a more comfortable injection experience, some people prefer letting the medication warm to room temperature before use, especially if it’s stored in the fridge.

Note: [Always seek professional advice regarding the use, storage, and disposal of the Mounjaro Pen, especially considering your health needs.]

Mounjaro Interactions

Insulin: For some people with Type 2 diabetes, managing blood sugar involves taking both insulin and other medications like Mounjaro. However, combining Mounjaro with insulin increases the risk of low blood sugar (hypoglycemia), which can be serious. It’s important to be extra careful when using these together.

Sulfonylureas Like Glipizide: This is another group of oral diabetes medications that signal the pancreas to release insulin. When combined with Mounjaro, there’s also an increased risk of hypoglycemia. Unlike Mounjaro, sulfonylureas prompt insulin release whether you’ve eaten or not, potentially causing too much insulin and leading to low blood sugar.

Glinides Like Repaglinide: These are a type of oral diabetes medicine that works differently than others. They make your pancreas release insulin quickly, but the effects don’t last as long. If you’re taking Mounjaro along with a glinide, there’s a higher chance of low blood sugar. To avoid this, your doctor might adjust your glinide dose when you start Mounjaro. Make sure to tell your doctor if you notice more low glucose levels after taking both medications.

Birth Control Pills: Another thing to be aware of is that Mounjaro can make birth control pills less effective, especially when you first start taking Mounjaro or increasing the dose. This could lead to unintended pregnancies or a return of symptoms. Mounjaro slows down how fast food moves through your stomach, affecting the absorption of birth control pills. 

Other Oral Medications: Mounjaro’s impact on stomach emptying can also affect how other oral medications are absorbed, particularly those sensitive to small dose changes, like warfarin. If you’re taking such medications, your doctor may suggest more frequent monitoring of your blood work when starting Mounjaro. 

Other Mounjaro Interactions

Herbs: While there is no specific information regarding herb interactions with Mounjaro, some herbs may pose a potential risk of lowering blood sugar when taken alongside Mounjaro. It is essential to consult with your doctor or pharmacist before incorporating these products into your Mounjaro treatment.

Vitamins: No specific reports indicate vitamin interactions with Mounjaro. Nevertheless, certain vitamins or minerals could potentially elevate the risk of low blood sugar when combined with Mounjaro. Therefore, it is advisable to seek guidance from your doctor or pharmacist before using any vitamin products concurrently with Mounjaro.

Food: There are no documented food interactions with Mounjaro. If you have inquiries about consuming specific foods during Mounjaro treatment, discussing this with your doctor is recommended.

Vaccines: No reports suggest interactions between vaccines and Mounjaro. If you are considering receiving particular vaccines while using Mounjaro, it is advisable to consult with your doctor.

Lab Tests: There are no documented interactions between lab tests and Mounjaro. Discussing this with your doctor is recommended if you are interested in undergoing specific lab tests while using Mounjaro.

Note: [Check with your healthcare provider or pharmacist to see if any of your medications may be affected by Mounjaro and how to manage it.]

Mounjaro Alternatives

• Ozempic (semaglutide)
• Repaglinide (meglitinides)
• Rybelsus (semaglutide)
• Nesina (alogliptin)
• Trulicity (dulaglutide)
• Victoza (liraglutide )
• Byetta (exenatide)
• Farxiga (dapagliflozin)
• Januvia (sitagliptin)
• Nateglinide (meglitinides)
• Onglyza (saxagliptin )
• Steglatro (ertugliflozin)
• Jardiance (empagliflozin)

Note: [Always follow your doctor’s advice. Only take other medicines if your doctor approves. Using them without asking your doctor can be dangerous.]

Quick Tips

To learn more about Mounjaro, please click the following links:

• How Often Can You Refill Mounjaro (Tirzepatide)?
• What Happens When You Stop Taking Mounjaro?
• Is Mounjaro Better Than Ozempic?
• How Long Does Mounjaro Stay in Your System?
• How Long Does Mounjaro Side Effects Last?
• Best Place to Inject Mounjaro for Weight Loss
• Learn more about which is better: Mounjaro or Trulicity

Frequently Asked Questions

How Long Does It Take for Mounjaro to Start Working?

Mounjaro starts working soon after you take your first dose, but it might take a while before you notice a difference in your blood sugar level. Some people see results in a few weeks after they begin using it. If you’re unsure about when you’ll see changes with Mounjaro, just ask your doctor.

Does Mounjaro Cause Fatigue?

Mounjaro generally doesn’t make you feel tired or weak. But if you’re experiencing fatigue, which is common in people with type 2 diabetes, it’s important to let your doctor know if the tiredness persists or gets severe.

Does the Mounjaro Injection Hurt?

People usually don’t complain about pain from the Mounjaro injection, but it might happen. Since Mounjaro is injected under the skin, you might feel a bit of pain or discomfort. Don’t worry; you or someone taking care of you will learn the right way to give the injection to reduce any pain at the spot where you get the shot.

When Was Mounjaro Approved by the FDA?

In May 2022, the FDA gave the approval to Mounjaro (tirzepatide) injection. It’s for adults with type 2 diabetes to help control blood sugar levels. Your doctor will suggest using it along with a diet and exercise routine. Just inject it under your skin in your stomach, thigh, or upper arm once a week, any time of the day.

Does Mounjaro Need to Be Refrigerated?

You can keep your Mounjaro single-dose Pen outside the fridge for 21 days, as long as the room isn’t hotter than 86ºF (30ºC). If it’s warmer, store it in the refrigerator at 36°F to 46°F (2°C to 8°C). Make sure to keep Mounjaro in its original box to keep it away from light.

Our Guarantee

At PolarBearMeds.com, we assure you the most affordable price to Buy Mounjaro from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently access Mounjaro at a substantial cost, call us at 1-888-779-2193 toll-free.