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What Is Plendil (Felodipine)?

Plendil, whose generic name is Felodipine, is a medication classified as a calcium channel blocker. It is commonly prescribed to manage high blood pressure (hypertension). Plendil works by relaxing and dilating blood vessels, which facilitates smoother blood flow, ultimately reducing blood pressure levels.  You can buy Plendil online as directed by a healthcare professional.

Dosage, Uses, and Storage

It’s crucial to understand the correct dosage, applications, and proper storage of Plendil (Felodipine) for effective treatment. This medication, classified as a calcium channel blocker, is primarily prescribed for managing high blood pressure. Let’s investigate the recommended dosages, critical applications, best Plendil 10 mg price and best practices for storing this medication.


A healthcare professional should determine the dosage of Plendil (Felodipine) based on individual patient needs, considering its uses and potential side effects. It’s crucial to consult a healthcare expert before starting any medication. The recommended starting dose is 5 mg once daily, which may be adjusted based on patient response. Controlling blood pressure is essential for overall cardiovascular risk management. Plendil at 20 mg once daily has an augmented antihypertensive effect, although adverse events may arise with higher dosages. Seniors and individuals with impaired liver function may require lower doses and careful blood pressure monitoring.


Felodipine, marketed as Plendil, alleviates hypertension and angina pectoris. Relaxing and dilating blood vessels improves blood circulation and reduces chest pain. For optimal results, take it orally daily on an empty stomach or with a light meal if needed. To enhance its effectiveness, avoid grapefruit and juice, maintain a consistent daily schedule, and do not discontinue without consulting a doctor. Complementing treatment with lifestyle changes like stress reduction, exercise, and dietary adjustments is advisable.

How to Store?

To properly store Plendil (Felodipine):

  • Keep it at room temperature, between 68°F to 77°F (20°C to 25°C).
  • Store in a dry place, away from direct sunlight and moisture.
  • Ensure it is out of reach of children and pets.
  • Avoid storing in the bathroom where moisture levels can be high.
  • Do not use Plendil if it has passed its expiration date; dispose of it correctly according to local regulations.

Following these guidelines will help maintain the effectiveness and safety of the medication.

How Does Plendil Work?

Plendil (Felodipine) operates through the following steps:

Calcium Entry Inhibition: It belongs to the class of drugs known as calcium channel blockers. When calcium channels in the cell membrane of vascular smooth muscle cells are activated, they allow calcium ions to enter. This triggers muscle contraction.

Blocking Calcium Channels: Felodipine specifically targets L-type calcium channels. Binding to these channels inhibits calcium influx into the smooth muscle cells.

Smooth Muscle Relaxation: With reduced calcium levels, vascular smooth muscle contractility decreases. This leads to relaxation and dilation of the blood vessels.

Enhanced Blood Flow: The widened blood vessels allow for smoother blood flow, reducing resistance to blood flow in arteries.

Lowered Blood Pressure: By reducing peripheral vascular resistance, Plendil effectively lowers blood pressure.

Decreased Cardiac Workload: With easier blood flow, the heart doesn’t have to work as hard to pump blood, further contributing to lowered blood pressure.

Overall, Plendil’s mechanism of action helps regulate blood pressure and is particularly beneficial in conditions like hypertension and angina pectoris. 

Warnings and Precautions

Plendil (Felodipine) is contraindicated in individuals with liver disorders due to its potential to elevate liver enzymes. Likewise, those with congestive heart failure should avoid Plendil, as it may increase the risk of hypotension and exacerbate symptoms. Individuals hypersensitive to Plendil or its components should refrain from its use to prevent severe reactions.

It is imperative to restrict or completely avoid consuming grapefruit and grapefruit juice while on felodipine treatment. This is because grapefruit products can significantly amplify the medication’s effects and blood levels.

Liver Failure

Due to its inability to be metabolized by the liver, Felodipine (Plendil) is not recommended for individuals with liver failure. Using this medication in such cases could lead to adverse effects, including elevated plasma levels of the medicine, rapid heartbeat, and increased liver enzyme levels. Healthcare professionals can evaluate suitability and suggest alternative treatments for high blood pressure in those with liver failure.

Congestive Heart Failure

Plendil is contraindicated for individuals with congestive heart failure, as it has the potential to increase cardiac index and systemic resistance. Studies have shown both short and long-term benefits in terms of improved exercise tolerance and reduced cardiac pressures. Prescribing Plendil for congestive heart failure patients requires careful consideration of risks and benefits.

Allergic Reactions

Individuals allergic to Felodipine should refrain from using Plendil to avoid serious allergic reactions. Additionally, it is advisable to abstain from alcohol and grapefruit juice while taking Plendil. Pregnant or breastfeeding women should exercise caution, as the safety of Plendil cost in this population has not been firmly established. You can get the best Plendil 10 mg price from a reputable Canadian pharmacy when you buy Plendil online.

Side Effects

Commonly reported side effects of Plendil may include:

  • Eruption
  • Irritation
  • Cephalalgia
  • Lightheadedness
  • Flushing
  • Exhaustion

Potentially more serious adverse reactions could occur, such as:

  • Swelling of the ankles
  • Quickened heart rate
  • Raised liver enzymes
  • Allergic responses

Patients should be aware of the potential risks associated with taking Plendil cost and consult a healthcare professional for any concerns or questions. It is crucial to follow your doctor’s instructions precisely to minimize the likelihood of serious side effects and potential interactions with other medications. If you experience severe side effects while using this medication, seek prompt medical attention.

What Are the Medications That Interact with Plendil?

Plendil (Felodipine) may interact with certain medications and substances. It’s crucial to inform your healthcare provider about all the medicines, supplements, and herbal products you are taking. Some notable interactions include:

  • Beta-blockers: Concurrent use of beta-blockers may increase the risk of heart problems. Close monitoring is advised.
  • CYP3A4 Inhibitors: Medications that restrict the CYP3A4 enzyme (e.g., certain antifungal drugs, macrolide antibiotics) can increase felodipine levels, potentially leading to side effects.
  • Grapefruit Products: Grapefruit and grapefruit juice can alter how Plendil is metabolized, potentially leading to increased levels in the blood.
  • CYP3A4 Inducers: Drugs that inhibit the CYP3A4 enzyme (e.g., rifampin) may decrease felodipine levels, reducing its effectiveness.
  • Other Antihypertensive Medications: Concurrent use of other blood pressure-lowering medications may lead to excessive blood pressure reduction.
  • Lithium: Felodipine may increase lithium levels in the blood, potentially leading to lithium toxicity.
  • Digoxin: Concurrent use may lead to an increased risk of digoxin toxicity.
  • Simvastatin: Co-administration with Plendil may increase simvastatin levels, potentially leading to muscle-related side effects.
  • Ciclosporin: Felodipine may increase ciclosporin levels in the blood.

When taking felodipine, you should avoid or limit the consumption of grapefruit and grapefruit juice. Medications like felodipine can be significantly increased by grapefruit juice.,plendil.html

Frequently Asked Questions

Is there an age limit for taking Plendil?

There is an age limit for taking Plendil, and those under 18 should abstain from using the medication due to potential risks and interactions with other medications. However, the specific age limit for taking Plendil should be determined by a healthcare professional based on an individual’s medical history and current health status. Always consult a doctor before starting or stopping any medication.

Does Plendil need to be taken with food?

Felodipine is typically recommended with a light, low-carbohydrate, and low-fat repast for optimal efficacy. It is important to adhere to the instructions given by your healthcare specialist since the dosage may vary. Furthermore, it is essential to remember that taking medication without food may lead to decreased absorption.

Is it safe to order Plendil from

If all precautions are taken, ordering Plendil from can be a secure experience. This pharmacy has received approval from relevant governing bodies, and its medications are procured from international pharmacies and distribution centers.

Can I stop taking Plendil abruptly or should I taper off?

You should not stop taking Plendil (Felodipine) abruptly without consulting your healthcare provider. Discontinuing the medication may lead to a sudden increase in blood pressure, which can be dangerous. Your healthcare provider will provide specific instructions on tapering off Plendil safely, if necessary. Always follow their guidance for a smooth transition.

Our Guarantee

Explore for the best Plendil 10 mg price from Canada when you buy Plendil online. Rest assured, your order will be dispatched from a licensed Canadian pharmacy. Our discounted products are promptly delivered from Canada to your doorstep. For budget-friendly access to this medication, contact us toll-free at 1-888-779-2193.


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