Zebeta

Zebeta is an FDA-approved antihypertensive drug used primarily to treat hypertension (high blood pressure) and other heart conditions such as arrhythmia and angina. It can be used alone or in combination with other high blood pressure medications. This drug contains the active ingredient Bisoprolol which is a beta-blocker, and it works by slowing down the heart rate. It then lowers the blood pressure and improves blood flow and oxygen supply to the heart. Zebeta is available in 5 mg and 10 mg oral tablets and is typically taken once daily, with dosage adjusted based on the patient’s response and condition. Common side effects include dizziness, headache, and fatigue. It’s essential to consult a healthcare professional for proper dosage and to monitor for any adverse effects or drug interactions.

Zebeta (bisoprolol fumarate) is a beta-adrenergic receptor blocker, commonly known as a beta-blocker, used to manage hypertension and various cardiovascular conditions such as arrhythmia, angina, and heart failure. High blood pressure puts extra strain on the heart and arteries. If this pressure is too high for too long, it can cause the heart and arteries to not work correctly. This can lead to damage in the blood vessels of the heart, brain, and kidneys, which can result in heart failure, stroke, or kidney failure. High blood pressure can also increase the risk of heart attacks. Controlling blood pressure can help reduce the likelihood of these health issues.

It is available in oral tablet form with 5 mg and 10 mg strengths. The medication works by reducing the heart rate and dilating blood vessels, which helps lower blood pressure and decrease the heart’s workload. Zebeta should be taken consistently, preferably in the morning, with or without food. Abrupt discontinuation should be avoided as it can lead to a sudden increase in blood pressure and potential heart complications. Long-term use is common, and the medication may be prescribed for life in some cases.

Common side effects include dizziness, headache, fatigue, and gastrointestinal disturbances. Serious side effects, such as severe allergic reactions, heart problems, and respiratory issues, should be reported to a healthcare professional immediately. Patients with certain medical conditions, such as severe heart failure, asthma, or diabetes, should use Zebeta cautiously and under close medical supervision. The medication may interact with other drugs, including other heart medications, alpha-blockers, and nonsteroidal anti-inflammatory drugs (NSAIDs), so it’s crucial to inform healthcare providers of all medicines being taken. Alternatives to Zebeta include other beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers, and diuretics, among others. The choice of medication depends on the individual’s specific health condition and medical history.

Zebeta, generic name Bisoprolol, is used to treat:

• Hypertension
• Eclampsia and Pre-eclampsia
• Renal Disorders and renovascular hypertension
• Cardiovascular Conditions, including hypertensive congestive heart failure and other related conditions
• Arrhythmia (irregular heartbeats) and Angina (chest discomfort)

Forms & Strengths of Zebeta?

It comes in the form of an oral tablet and has the two following strengths:

• 5 mg
• 10 mg

What Is the Recommended Dosage of Zebeta for Different Patients?

Bisoprolol Zebeta 5 mg tablet dosage is based on the needs, age, and patient’s response to treatment. However, if your doctor has recommended you to follow a dosage schedule that is different from the one mentioned above, you should follow their guidance and so not change the dose without consulting your doctor, as it can cause undesirable side effects or other issues. The recommended dosage mentioned below is a generalized dosage and can vary from person to person. Contact an expert medical practitioner for more information.

Dosage for High Blood Pressure (Hypertension)

For Children (0 to 17 Years)

• A healthcare professional will decide the appropriate use and dosage of this medication.

For Adults (18 to 64 Years)

• Initial Dosage: 5 mg once daily
• Dosage Increases: If you are not responding to your initial dosage, your doctor can increase the dose to 10 mg once daily.
• Maximum Dosage: 20 mg daily

For Seniors (65 Years & Older)

• As you get older, your organs, like the kidneys and liver, might not function as effectively as before. This can lead to a higher amount of medication remaining in your body. To address this, your doctor may prescribe a lower dosage to start with.

Dosage Considerations for People with Health Conditions

Asthma or Respiratory Disease

Your doctor will probably begin your treatment with a small dose of bisoprolol, typically 2.5 mg daily, and gradually increase it. If the dose becomes too high, bisoprolol may affect not only your heart but also your lungs.

Kidney or Liver Problems

Your doctor may start you on 2.5 mg of Zebeta per day. Your doctor will take care when increasing your dosage.

[Note: Remember these recommendations may vary depending on person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

Before using bisoprolol Zebeta 5 mg tablet for the first time, and each time you get a refill, you should carefully read & follow the directions given in the patient information leaflet that came along with your prescription label and, if available, the medication guide. If you do not understand any part of the leaflet or if you have any questions regarding the safe and effective use of the medication, talk to your doctor. The general guidelines for using Zebeta include the following:

• You should generally take Zebeta once a day in the morning.
• Your doctor might suggest taking your first dose at bedtime to see if it makes you dizzy. If you don’t feel it after the first dose, continue taking it in the morning.
• You can take Zebeta with or without food, as it doesn’t typically upset the stomach.
• Swallow the tablets with water.
• Some Zebeta tablets have a score line to help you break them for easier swallowing; check the information leaflet for your specific brand to see if this applies.
• This medication is usually prescribed for long-term use, potentially for life.
• Stopping Zebeta abruptly can increase your blood pressure, raising your risk of heart attack and stroke. If you’re considering stopping the medication, talk to your doctor first.
• This medication can be refilled without a new prescription. Your doctor will specify the number of refills allowed on your prescription.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

Zebeta is called a beta-blocker, which works by changing how your body responds to nerve signals, particularly in your heart. This slows down your heart rate and lowers your blood pressure. When your blood pressure is reduced, your heart receives more blood and oxygen, which is beneficial for its health. This further helps in reducing the risks of cardiovascular events such as heart failure and heart stroke.

Common side effects of Zebeta: Similar to other medications, Zebeta may also cause certain undesirable side effects in some users. Zebeta is considered to be generally safe for use, and not everyone taking it will experience these side effects. Most of the symptoms do not require medical attention and disappear on their own within a couple of days or weeks as your body starts to adjust to the medication. Some of the common side effects of Zebeta are as follows: 

• Diarrhea: If this medication makes you vomit or gives you severe or persistent diarrhea for more than 24 hours, the birth control pills you may be taking will not be able to protect you from pregnancy. Check the packet of the contraceptive pill to protect yourself from getting pregnant. 
• Dry or Burning Eyes: Zebeta can cause severe eye problems, such as burning or dry eyes, pain in the back of the eyes, blurred vision, and difficulty reading during or after treatment. 
• Cold Or Flu Symptoms: Bisoprolol fumarate can cause side effects that may mimic cold or flu-like symptoms such as cough, chills, fever, nasal congestion, body ache or pain, and headache. 
• Dizziness: This medication may cause a drop in your blood pressure, which can cause a sudden decline in your BP. This sudden change can disrupt the flow of blood to your brain, further making you feel lightheaded or dizzy. This is because the brain temporarily receives less oxygen and nutrients than it needs. 
• Headache: Due to its effects on your blood pressure, Bisoprolol Zebeta 5 mg tablet can cause the brain’s blood vessels to narrow or dilate, which can cause headaches. This side effect may also occur when you initially start taking this medication. 
• Anxiety: This medication can affect the nervous system, which controls your heart rate and blood pressure. It can also influence the chemicals in your brain, including neurotransmitters, which can lead to anxiety or nervousness, especially when you initially start using Zebeta.
• Changes In Sex Drive Or Performance: Beta-blockers, including Zebeta, can affect the sex drive or performance. It can also increase the chances of erectile dysfunction by reducing nitric oxide levels. If you experience changes in your sexual performance after starting this medication, you should tell your healthcare provider. They may suggest you adjust your medication dosage or switch to a different prescription. 
• Nausea: This medication can affect your digestive system, leading to nausea and other digestive issues. This side effect may happen because beta blockers, including Zebeta, can slow down digestion or irritate the stomach lining, causing stomach discomfort. 
• Weakness: Zebeta can reduce the heart rate and the force of the heart’s muscle contractions, which can make you feel weaker than usual. This happens because your muscles are receiving less blood supply enriched with nutrients and oxygen. 
• Fatigue: Since this medication reduces heart activity and blood pressure, your body might feel like it is putting more effort into normal activities, leading to a feeling of unusual fatigue or tiredness. This may also occur due to the overall lowering of metabolic rate influenced by the medication. 
• Slower Heart Rate: Zebeta is a beta-blocker that blocks the beta-adrenergic receptors in the heart, leading to a drop in the heart rate. This helps to reduce blood pressure and strain on the heart, but it can also make your heart rate unusually slow, known as bradycardia.

These side effects might disappear in a few days or weeks if they are not severe. However, if they are serious or persist, you should consult your doctor or pharmacist.

Mild Side Effects of Zebeta: In some cases, this medication may cause mild side effects in some people using it to manage hypertension and various cardiovascular conditions. You should report any new or worsening symptoms to your doctor immediately and consult your medical team if you have any concerns or questions regarding Zebeta use. It is important to mention that this list is not exhaustive, and there may be other side effects caused by this medication. Mild Side Effects of Zebeta may include: 

• Headache: Zebeta can cause headaches in some people. This might happen because beta-blockers like Zebeta change the way blood flows through your vessels. When the force of the heartbeat is reduced, it can cause changes in blood pressure & blood flow to different parts of the body, including the brain. This alteration can trigger headaches.
• Insomnia: Beta-blockers, including Zebeta, can affect sleep patterns and neurotransmitters in the brain, altering melatonin levels and disturbing the natural sleep-wake cycle, leading to sleep disturbances.
• Joint pain: This is a less common side effect, and the exact mechanism isn’t completely clear. However, it might be related to changes in blood flow to the joints or an alteration in the way the body perceives pain due to the effects of the medication on the nervous system.
• Swelling: Medically known as edema, swelling can occur with Zebeta use due to its effect on the kidneys and blood vessels. Beta-blockers can lead to fluid retention in the body, which can accumulate in the tissues and cause swelling, especially in the legs and ankles.
• Common cold symptoms such as stuffy, runny nose, cough, and sore throat: Beta-blockers, including Zebeta, can affect the respiratory system and cause the airways to narrow slightly, which can lead to symptoms similar to those of cold. People who have respiratory issues,- such as asthma & COPD, have an increased risk of developing these symptoms. 

Serious Side Effects of Zebeta: Rarely, bisoprolol fumarate can cause serious symptoms in some patients belonging to certain groups. These severe side effects require prompt medical attention and can become fatal if not treated promptly. Get in touch with your doctor or call 911 immediately if you experience any of the symptoms mentioned below. Severe side effects & their symptoms may include the following: 

• Worsening Heart Failure and Fluid Buildup: Bisoprolol might worsen your condition if you have a history of heart issues. Bisoprolol fumarate can cause your body to retain fluid, which might lead to heart failure over time. Keep an eye on symptoms like difficulty breathing when lying down, swelling in the legs, ankles, or feet, sudden weight gain, and unusual fatigue.
• Heart Rate Changes (Bradycardia): Bisoprolol can slow your heart rate, a condition known as bradycardia. If you notice you’re feeling lightheaded, dizzy, or fainting; experiencing confusion; feeling unusually weak or tired; having chest pains; or shortness of breath, it’s important to contact your doctor immediately.
• Low Blood Pressure (Hypotension): This medication might also cause your blood pressure to drop, making you feel faint or dizzy. You should lie down and call your healthcare provider if these symptoms occur. Look out for signs like confusion or feeling excessively weak or tired.
• Peripheral Vascular Disease: Bisoprolol can worsen blood flow problems, especially to the arms, legs, and intestines, by affecting how the heart pumps blood. This can exacerbate existing conditions related to poor blood circulation.
• Breathing Problems: Bisoprolol can sometimes tighten the muscles around your airways, significantly worsening breathing problems. If you experience trouble breathing, it’s crucial to discontinue taking Zebeta and seek medical advice immediately.
• Masked Symptoms of Low Blood Sugar (Hypoglycemia): For those with diabetes, bisoprolol can hide early warning signs of low blood sugar or hypoglycemia, like a rapid heartbeat. This can make hypoglycemia more dangerous. You should be careful while using this medication and look out for other low blood sugar indicators such as headaches, irritability, hunger, dizziness, confusion, blurry vision, slurred speech, sweating, jitteriness, or even seizures.
• Severe Allergic Reactions: Bisoprolol can sometimes trigger serious allergic reactions. Symptoms to watch for include difficulty breathing, heart palpitations, fever, swollen lymph nodes, swelling of the face or throat, trouble swallowing, itchy rash or hives, nausea, vomiting, dizziness, stomach cramps, or joint pain. If any of these occur, seeking immediate medical attention is important.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

While using Zebeta, there are certain warnings that you should keep in mind. The key points of the warnings include:

• Cardiac Failure: Zebeta, which is a beta-blocker, can sometimes make heart failure worse because it can decrease the heart’s ability to pump blood. Generally, patients with severe heart failure should not use beta-blockers. However, in some cases where heart failure is under control, beta-blockers may be needed but should be used cautiously.
• For Patients Without Heart Failure History: In some patients, beta-blockers can lead to heart failure. If you start showing signs of heart failure while taking Zebeta, you should consider stopping the medication. If heart failure develops, beta-blocker therapy might continue while treating the heart failure with other medicines.
• Abrupt Cessation of Therapy: Stopping beta-blockers suddenly can worsen Angina (chest pain), cause a heart attack, or lead to irregular heartbeats in patients with heart disease. If you need to stop taking Zebeta, do it gradually over about a week, under close medical supervision. If you experience withdrawal symptoms, you may need to start taking Zebeta again temporarily.
• Peripheral Vascular Disease (Poor Blood Circulation): Beta-blockers can worsen symptoms in patients with poor blood circulation in their limbs. Be cautious if you have this condition.
• Bronchospastic Disease (Asthma and Breathing Problems): Generally, patients with asthma or other breathing problems should avoid beta-blockers. Zebeta may be used with caution in some patients with breathing problems who cannot tolerate other blood pressure medications. Since Zebeta mainly affects the heart and not the lungs, it may be safer, but it should be used at the lowest effective dose. Always have a fast-acting inhaler (bronchodilator) available.
• Before Major Surgery: If you are taking beta-blockers regularly, do not stop them before major surgery. Stopping them can increase the risks associated with anesthesia and surgery because the heart may not respond well to stress.
• Diabetes And Hypoglycemia: Beta-blockers can hide signs of low blood sugar, especially a fast heartbeat. They can also make low blood sugar worse and slow down recovery. Zebeta is less likely to do this because it is selective for the heart, but patients with diabetes or those prone to low blood sugar should be cautious.
• Thyrotoxicosis (Overactive Thyroid): Medicines containing beta-blockers can hide signs of an overactive thyroid, like a fast heartbeat. Stopping them suddenly can make thyroid symptoms worse or trigger a thyroid crisis.

Before using the bisoprolol Zebeta 5 mg tablet, share your entire medical and family history with your doctor and tell them about all the medications you are using. Also, consider the following precautions for people belonging to certain groups to ensure safe and effective medication use.

• For People with Heart Problems: Avoid using this medication if you have difficulty pumping blood, active heart failure, a second or third-degree heart block, or a slow heartbeat (bradycardia). These conditions mean your heart is already struggling to function properly. Taking bisoprolol could worsen your situation by making it harder for your heart to pump blood. If you have heart failure that’s under control with medication (compensated heart failure), this drug might make your heart failure worse.
• For People with Lung Diseases: If you have lung conditions like asthma or other breathing issues, you should generally avoid taking bisoprolol. However, if you can’t tolerate other high blood pressure medications, your doctor might let you use them at the lowest possible dose. Make sure to have a beta-agonist inhaler, like albuterol, on hand.
• For People with Peripheral Vascular Disease: This medication could make the symptoms of your condition worse. 
• For People with Hyperactive Thyroid: Bisoprolol may hide the signs of an overactive thyroid (hyperthyroidism). If you stop taking bisoprolol suddenly, your thyroid symptoms could become more severe, or you could develop a serious condition known as thyroid storm.
• For People with Diabetes: This medication can hide signs of low blood sugar (hypoglycemia). It may also delay the time it takes for your blood sugar to return to normal levels. If you have diabetes, especially if you are using insulin or other medications that lower blood sugar, you should use Bisoprolol carefully.
• For People with Pain, Cough, Cold, or Allergies: Speak with your healthcare provider or pharmacist. They can assist you in finding a safe medication to use alongside bisoprolol.
• Alcoholism: Drinking alcohol can lower your blood pressure. If you take bisoprolol, drinking alcohol might make your blood pressure too low.
• Pregnancy: If you are pregnant or planning to get pregnant, talk to your doctor. Research in animals has shown harm to the baby when the mother takes this medication. There isn’t enough information from human studies to know how it might affect the baby. This medication should only be used if the benefits outweigh the risks.
• Breastfeeding: It’s not known if bisoprolol passes into breast milk. If it does, it could harm a breastfed baby. You and your doctor should decide whether you should take bisoprolol or breastfeed.
• Children: The safety and effectiveness of bisoprolol in people under 18 years old haven’t been established.
• Surgery: If you’re going to have surgery, tell your doctor. They will need to keep an eye on your heart and blood pressure and check for any interactions with other drugs.

This medication is contraindicated in patients with:

• Overt cardiac failure
• Cardiogenic shock
• Second or third-degree AV block
• Marked sinus bradycardia

In case of a missed dose:

Take it immediately when you remember.

If the next dose is approaching, omit the missed dose and proceed with the next scheduled dose.

Avoid taking a double dose.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

If you think you have taken too much of this medication, contact your doctor right away. Call 911 or go to the nearest emergency room immediately if you have severe symptoms. Common signs of an overdose include:

• A slower-than-normal heart rate
• Lower than-normal blood pressure
• Heart failure
• Lower than-expected blood sugar levels
• Bronchospasm (a condition where the airways in your lungs tighten, making it difficult to breathe)

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

Following proper storage guidelines helps ensure that the medication you are using is effective.

• Keep this medication at an average room temperature, between 68°F and 77°F (20°C and 25°C).
• Avoid storing it in wet or humid places, like bathrooms.
• Do not keep medications that are outdated or no longer required. Discard them in such a way that children, animals, and other people cannot consume them and they cannot cause pollution to the environment.
• Follow the instructions of the local waste disposal company or your pharmacist for the safe disposal of unwanted medications.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Zebeta oral tablets can affect or be affected by other medicines, vitamins, or herbal supplements you’re taking. When two substances interact, they can change how a drug works, which might be harmful or stop the drug from being effective. To avoid any problems, your doctor should carefully manage all your medicines. There are certain drugs that can interact with bisoprolol, the active ingredient in Zebeta. Some examples are listed below:

Heart Rhythm Drugs: These medications can cause a slower heart rate or more side effects when taken with bisoprolol. If you are prescribed these medications alongside bisoprolol, your doctor will closely monitor your condition. They may also adjust the dosage of your medications. Examples of these drugs include:

• Digoxin
• Bretylium
• Propafenone
• Disopyramide
• Flecainide
• Amiodarone
• Quinidine
• Sotalol
• Procainamide
• Encainide

Beta-blockers: Bisoprolol should not be combined with other beta-blockers, as this can excessively reduce your heart rate. Examples of these drugs are:

• Clonidine
• Metoprolol
• Atenolol
• Carvedilol
• Reserpine
• Propranolol
• Diltiazem
• Acebutolol
• Non-dihydropyridine calcium channel blockers
• Dihydropyridine calcium channel blockers

Anti-infective drug: Taking rifampin together with bisoprolol can increase the speed at which bisoprolol is eliminated from your body. This may reduce the effectiveness of bisoprolol in treating your condition.

Alpha-blockers: Taking these medications can lead to a decrease in your blood pressure when you move from a sitting to a standing position or from lying down to sitting up. This increases your risk of falling. Examples of these drugs include:

• Prazosin
• Terazosin
• Doxazosin

Anesthetic: Bisoprolol can interfere with how your body removes the numbing medication lidocaine, potentially leading to harmful levels of lidocaine in your blood. If you are taking both medications, your doctor may monitor your blood levels to ensure your safety.

Malaria drug: Taking mefloquine (malaria drug) together can lead to irregular heartbeats, and there’s a risk that your heart might stop functioning.

Stimulants: Avoid using stimulants with bisoprolol, as they can interfere with its effectiveness. Taking them together may result in both drugs not working as intended. Some examples of these stimulants include:

• Phenylephrine
• Norepinephrine

Nonsteroidal anti-inflammatory drugs (NSAIDs): These medications can reduce the effectiveness of bisoprolol in lowering blood pressure. Examples of these medications include:

• Nabumetone
• Sulindac
• Indomethacin
• Piroxicam
• Naproxen

[Note: This isn’t a complete list, and there could be other drugs that interact with Zebeta. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Other Zebeta Interactions?

Certain food items, beverages, herbs, and supplements may interact with Zebeta. Consuming alcohol or tobacco-containing products may also cause interactions. To avoid these interactions, your doctor may suggest you make certain dietary and lifestyle changes. Apart from these interactions, this medication may also affect or be affected by certain diseases. These include:

• Congestive heart failure
• Coronary artery disease
• Respiratory issues such as asthma or COPD.
• Diabetes
• Liver disease
• Kidney disease
• Thyroid disorders
• Allergic reaction to Zebeta, bisoprolol fumarate, or other ingredients present in the medication.

While Zebeta is an effective medication used to manage hypertension and other cardiovascular conditions, it can cause unwanted side effects in some users or fail to provide desirable results. In such cases, people look for effective substitutes for Zebeta. Many popular alternatives of Zebeta are available on the market, but you should not change the brand or type of medication you are using without consulting your medical team. Some of the popular alternatives to Zebeta are given below.

• Entresto (sacubitril/valsartan)
• Cozaar (losartan)
• Lanoxin (digoxin)
• Nebivolol (bystolic)
• Lopressor (metoprolol tartrate)
• Cardizem (diltiazem)
• Toprol XL (metoprolol succinate)
• Aldactone (spironolactone)
• Inderal (propranolol)
• Coreg (carvedilol)
• Blocadren (timolol)
• Prinivil, Zestril (lisinopril)
• Calan SR (verapamil)
• Tenormin (atenolol)
• Coreg CR (carvedilol extended-release)
• Trandate (labetalol)
• Bidil (hydralazine/isosorbide dinitrate)
• Hydrochlorothiazide
• Lasix (furosemide)
• Norvasc
• Corlanor (ivabradine)
• Metoprolol

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

The cost of Zebeta (bisoprolol), a cardioselective beta blocker, can vary depending on factors such as health insurance coverage & the pharmacy you choose. While some insurance plans may cover the medication, others might not, resulting in higher out-of-pocket expenses. Options like purchasing from reputable Canadian pharmacies, such as Polar Bear Meds, are available to help manage these costs. You can also use the Zebeta coupon code WELCOMEPB10 to get a 10% discount on your first order, offering additional savings on your medication.

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The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.