Fluticasone Propionate, Salmeterol Xinafoate

Advair Diskus Inhaler

Wixela Inhub, the first Advair Diskus generic version, is an FDA-approved medication that combines fluticasone propionate and salmeterol to effectively manage asthma and COPD. Fluticasone reduces inflammation, while salmeterol relaxes airways, enhancing breathing. It is administered via inhalation, with dosages varying based on the individual’s condition. Safety guidelines emphasize not using Advair Diskus as a rescue medication for sudden symptoms. Common side effects include sore throat and upper respiratory infections. Patients should adhere to prescribed dosages and store the medication at room temperature. Lastly, if you are looking for online options to treat your asthma or COPD, reach out to Canadian pharmacies like Polar Bear Meds. Here, you will get quality inhalers, and if you are concerned about the Advair HFA inhaler price, this platform can offer affordable medications compared to traditional pharmacies.

Product Overview

Advair Diskus is a prescription medication that combines two active ingredients: fluticasone propionate, a corticosteroid that lowers inflammation in the airways, and salmeterol, a long-acting beta-agonist (LABA) that relaxes and opens the airways. It is used for the long-term management of asthma and chronic obstructive pulmonary disease (COPD), providing relief from symptoms like wheezing, coughing, and shortness of breath. Advair Diskus is approved by the FDA for these conditions and works by preventing and controlling symptoms to improve lung function over time.

Available in three strengths (100 mcg/50 mcg, 250 mcg/50 mcg & 500 mcg/50 mcg), Advair Diskus is taken as one inhalation twice daily, with dosages determined by the severity of the condition & the patient’s response to treatment. It is suitable for adults and children aged 4 years and older for asthma management and for adults with COPD. The medication works by delivering the active ingredients directly to the lungs, where they exert their effects to reduce inflammation and open airways for better breathing.

Common side effects of Advair HFA inhaler include sore throat, headache, and upper respiratory infections. It is important to follow the prescribed dosage and not use Advair Diskus as a rescue medication for sudden breathing problems. In case of a missed dose, skip it and continue with the next scheduled dose. Store the medication at room temperature & keep it in its original, unopened foil pouch until ready to use. Patients should consult their healthcare practitioner for advice on side effects, precautions, and proper use of Advair Diskus to ensure safe and effective treatment.

What Are the Uses of Advair Diskus?

This medication is used for the following purposes:

• Treatment for managing asthma
• Treatment for managing chronic obstructive pulmonary disease (COPD)

What Are the Forms & Strengths of Advair Diskus?

Advair Diskus is available in three different strengths: 

• 100 mcg/50 mcg (fluticasone/salmeterol)
• 250 mcg/50 mcg (fluticasone/salmeterol)
• 500 mcg/50 mcg (fluticasone/salmeterol)

What Are the Recommended Advair Dosages for Different Patients?

The recommended dosage of Advair Diskus depends on the patient’s condition, the severity of their symptoms, and their previous response to similar medications. Therefore, patients are advised to always consult a medical practitioner before considering treatment with this inhaler. Generally, your doctor prescribes you a starting dose and gradually titrates the doses based on your response to the treatment. Advair Diskus is commonly prescribed for asthma and chronic obstructive pulmonary disease (COPD), with dosages tailored to these conditions. So, if you have been prescribed a different dose, do not change it until your practitioner advises otherwise.

For Patients with Asthma

• For adults and children aged 12 years & older: The dosage will be determined by your healthcare practitioner based on the severity of your asthma and any other medications you may be taking. The typical dosage is one inhalation taken orally twice daily.
• For children aged 4 to 11 years: The typical dosage is one inhalation of Advair Diskus 100 mcg/50 mcg (fluticasone/salmeterol) taken orally twice daily.

For Patients with COPD 

• The typical dosage for COPD is one inhalation of Advair Diskus 250 mcg/50 mcg (fluticasone/salmeterol) taken orally twice daily.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]

How to Use Advair Diskus?

Using an Advair HFA inhaler involves a specific process to ensure the medication is delivered correctly. Here is the step-by-step guide on how to use your inhaler:

• Open the Device: Hold the Advair Diskus in one hand and put the thumb of your other hand on the thumb grip. Push the thumb grip until the mouthpiece appears and snaps into position.
• Prepare the Dose: Hold the device with the mouthpiece towards you. Slide the lever away from you until it clicks. This means the dose is ready to be inhaled.
• Inhale the Medication: Before inhaling, breathe out fully away from the device (never breathe into the device). Then, put the mouthpiece to your lips, close your mouth around it, and breathe in quickly and deeply through your mouth. Do not block the air vent with your fingers. Remove the device from your mouth and hold your breath for about 10 seconds, or as long as is comfortable. Then, breathe out slowly.
• Close the Device: After use, close the device by sliding the thumb grip back towards you until it clicks shut.
• Rinse Your Mouth: Rinse your mouth with water after each dose to reduce the risk of infections in the mouth. Do not swallow the water.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Advair Diskus Work?

Advair Diskus is a combination medication that contains fluticasone and salmeterol. Fluticasone is a corticosteroid that reduces inflammation in the airways, while salmeterol is a long-acting beta-agonist (LABA) that relaxes and opens the airways. Together, these components help prevent and control asthma symptoms such as wheezing, coughing, and shortness of breath, as well as improve lung function. It is important to note that Advair Diskus is not intended for the immediate relief of acute asthma attacks or sudden symptoms of COPD but is used as a long-term maintenance treatment.

Important Safety Information

What Are the Side Effects of Advair?

Common Side Effects of Advair: Like all medications, this inhaler can cause certain side effects. These reactions are temporary, generally lasting from a few days to weeks. Some of them may disappear on their own without the need for medical attention. However, if these effects persist for a long time or intensify, talk to your doctor immediately. Some of its common side effects may include:  

• Sore Throat: This is a frequent side effect as the medication can irritate the throat lining.
• Headache: Some users experience headaches, which may be due to the body adjusting to the medication or other related mechanisms.
• Upper Respiratory Infection: Advair Diskus can affect your immune system’s capability to fight off infections, potentially leading to upper respiratory infections.
• Cough: The inhalation of the medication can trigger a cough reflex or irritate the airways, resulting in coughing.
• Bronchitis: Since Advair Diskus is used for inhalation, it can lead to inflammation of the bronchial tubes, sometimes causing bronchitis, especially if you are already prone to respiratory issues. So, before you buy Advair Inhaler online, consider this important side effect.
• Nausea and Vomiting: Although less common, some people may experience gastrointestinal signs like nausea and vomiting as a side effect.
• Hoarseness: The medication can cause irritation and dryness in the throat, leading to hoarseness or changes in voice.

Serious Side Effects of Advair: This inhaler combines fluticasone propionate & salmeterol xinafoate, which can cause severe side effects in certain patients if not taken properly. If you suspect any unwanted signs, consult a medical professional. Overlooking them may cause life-threatening situations. So, beware of the following side effects:

• Severe Allergic Reaction: This includes hives, which are red, itchy welts on the skin; swelling of the lips, face, or tongue, which can impede breathing and swallowing; and difficulty breathing. Such allergic reactions can quickly escalate into anaphylaxis, a life-threatening condition that requires urgent treatment. Immediate medical help is critical. Patients are advised to use an epinephrine auto-injector if they have one and seek emergency medical care.
• Sudden Narrowing of Airways: This condition is characterized by sudden difficulty breathing, wheezing, chest pain or tightness, and coughing. Widely known as bronchospasm, this reaction can dangerously reduce airflow, making it difficult to breathe. This is considered a medical emergency, especially in patients with asthma or COPD, as it can lead to severe breathing difficulties. Immediate medical intervention is necessary.
• Heart Problems: These may include dizziness, fatigue, tremors, nausea, a rapid heartbeat, weakness, and difficulty sleeping. These symptoms could indicate that the heart is under strain or not functioning properly, which can lead to more severe cardiac issues if not addressed. Patients experiencing such signs should contact their healthcare provider promptly. Monitoring and possibly adjusting the treatment may be required to prevent more severe heart conditions.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

What Are the Advair Warnings?

Advair Diskus, the generic version of Wixela Inhub, contains a combination of fluticasone propionate and salmeterol xinafoate. It comes with several warnings that are important for users to be aware of so that they can use the medication safely and effectively. Here are the key warnings associated with this medication:

• Allergies: Do not use Advair if you have allergies to fluticasone, salmeterol, or milk proteins.
• Not a Rescue Medicine: Advair is not intended for quick relief during an asthma or bronchospasm attack.
• Medical Attention: If your breathing worsens or you feel your medications are not effective, seek medical help.
• Fungal Infections: Using Advair may increase the risk of fungal infections in the mouth and throat. To reduce this risk, rinse your mouth with water after each use. If you are experiencing these infections, use antifungal medicines or consult your medical practitioner.
• Risk of Pneumonia: Advair may increase the likelihood of pneumonia in individuals with COPD.
• Severe Asthma-Related Problems: Using LABA medications, including Advair, alone without an inhaled steroid, especially for asthma, is highly likely to cause life-threatening situations like death. It also increases the risk of hospitalizations in children and teens. 
• Exacerbated Asthma or COPD: This inhaler is not recommended for patients with worsening conditions. Doing so may cause serious breathing problems.
• Switching from Oral Steroids to Inhaled Steroids: If you have shifted from oral to inhaled steroids, you may need special care. There have been reports of deaths due to adrenal insufficiency during and after the transition. 

What Are the Advair Precautions?

Several precautions should be observed when using Advair to ensure safe treatment. Here are the important precautions of Advair Diskus before using:

• Do not use this medication if you are allergic to fluticasone or salmeterol (Serevent), have a severe milk protein allergy, or are experiencing an asthma attack or severe COPD symptoms.
• Fluticasone may lower your immune system, increasing your susceptibility to infections or worsening existing ones. Inform your doctor about any recent illnesses or infections.
• Discuss with your doctor if you have a history of glaucoma, cataracts, heart disease, high blood pressure, seizures, diabetes, allergies, a weakened immune system, chronic infections (such as tuberculosis or herpes of the eye), osteoporosis, thyroid disorders, or liver or kidney disease.
• Long-term steroid use may lead to osteoporosis, particularly if you smoke, are inactive, or lack vitamin D or calcium in your diet. Discuss your risk with your doctor.
• If you are pregnant, inform your doctor. The effects of this medication on an unborn baby are unknown, but untreated asthma during pregnancy can lead to complications. The benefits of treating asthma may outweigh the potential risks to the baby.

What Are the Advair Contraindications?

Advair Diskus has specific contraindications that should be considered to ensure it is used safely. Here are the primary contraindications for using Advair:

• Advair Diskus should not be used as the first-line treatment for status asthmaticus or acute episodes of asthma or COPD that necessitate intensive therapy.
• Similarly, Advair HFA is not suitable as the initial treatment for status asthmaticus or acute asthma episodes requiring intensive therapy.
• Both Advair Diskus and Advair HFA are contraindicated in individuals with a history of hypersensitivity to any of their active or inactive components, including milk proteins found in Advair Diskus.

What Happens If You Miss a Dose of Advair?

If you happen to miss a dose of Advair Diskus, simply skip the missed dose and continue with your next dose at the usual scheduled time. Avoid taking two doses of Advair Diskus to compensate for the missed dose, as this could lead to severe side effects. Before you buy Advair inhaler online, consult your doctor about how many you should buy. 

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

What Happens If You Take Too Much Advair? 

Overdosing any medication can cause several adverse reactions. Therefore, patients are strictly advised not to use their Advair HFA inhaler more than the prescribed dose. However, if you have taken an exceeding amount of your medication, you may experience the following overdose symptoms: 

• Chest pain
• Rapid heartbeat
• Shakiness 
• Difficulty breathing
• Changes in blood pressure
• Dizziness
• Dry mouth
• Nausea
• Fatigue
• Muscle cramps
• Seizures

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

How Do You Store Advair?

Proper storage of Advair Diskus is crucial to ensure its effectiveness. Here are the recommended storage guidelines for your inhaler:

• Keep Advair Diskus at a temperature range of 68°F to 77°F (20°C to 25°C). Store in a dry area, avoiding direct heat or sunlight.
• Maintain the Advair Diskus in its original, unopened foil pouch. Open the pouch only when you are ready to use the medication.
• Dispose of Advair Diskus in the trash one month after opening the foil pouch or when all medication blisters are used (indicated by a dose counter reading “0”), whichever occurs first.
• Keep the inhaler away from light, extreme heat, and moisture.
• Avoid keeping the product in moist or damp places.
• Do not keep it near high temperatures, as there are chances that it may burst.
• Do not use the product after its expiration date. You can check the date on the product’s back or read the label.
• Dispose of the medication safely without damaging the environment. Ask your doctor for proper disposal.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

What Medications Interact with Advair Diskus?

Advair Diskus can interact with several other medications, potentially altering their effects or increasing the risk of adverse reactions. Here are some notable interactions to be aware of:

• Beta-Blockers (like atenolol, metoprolol, and propranolol): May reduce the effectiveness of Advair Diskus and increase the risk of bronchospasm.
• Diuretics (like furosemide and hydrochlorothiazide): Can enhance the potential for hypokalemia (low potassium levels) when used with Advair Diskus.
• Monoamine Oxidase Inhibitors (MAOIs) and Tricyclic Antidepressants (like phenelzine and amitriptyline): Can increase the risk of cardiovascular side effects when used with Advair Diskus.
• Other Beta2-Agonists (like albuterol and salmeterol): Using these medications together with Advair Diskus may increase the risk of side effects.
• CYP3A4 Inhibitors (like ketoconazole, ritonavir, and clarithromycin): Can increase the systemic exposure to fluticasone, one of the components of Advair Diskus, leading to increased risk of side effects.
• Corticosteroids (like prednisone and methylprednisolone): Concurrent use with Advair Diskus may increase the risk of systemic corticosteroid side effects.
• Antifungal Medications (itraconazole): Can increase the levels of fluticasone in the body and increase the risk of side effects.
• HIV Protease Inhibitors (like indinavir and ritonavir): Can increase the levels of fluticasone in the body and increase the risk of side effects.
• Anticholinergics (like ipratropium and tiotropium): Concurrent use with Advair Diskus may increase the risk of side effects.
• Cardiac Glycosides (digoxin): May increase the risk of irregular heart rhythms when used with Advair Diskus.

What Are the Other Advair Interactions?

Advair can interact with other substances like supplements, herbs, vitamins, and certain foods. Here are some other interactions of Advair you should know about:

• Advair and Alcohol: Advair is not known to interact with alcohol. However, if you have particular side effects from Advair, such as headache, nausea, and dizziness, drinking alcohol could worsen them.
• Advair and Supplement: Before initiating treatment with Advair, it is crucial to inform your doctor and pharmacist about any supplements, herbs, or vitamins you are currently taking. Sharing this information can help you prevent potential interactions.
• Herbs and Advair: To date, no specific interactions between herbs and Advair have been reported. However, this does not guarantee that herb interactions won’t be discovered in the future. Always verify with your healthcare provider before combining any herbal products with your Advair treatment.
• Vitamins and Advair: Similarly, no specific vitamin interactions with Advair have been identified. Nonetheless, the absence of reported interactions does not eliminate the possibility of future occurrences. Discuss with your healthcare professional before taking any vitamins along with Advair.
• Food Interactions with Advair: Advair has potential interactions with certain foods, particularly grapefruit and grapefruit juice, as well as caffeine.
  • Grapefruit and Grapefruit Juice: It’s likely your doctor will recommend avoiding grapefruit and grapefruit juice while on Advair. Grapefruit can inhibit an enzyme essential for metabolizing Advair in your body, leading to increased drug levels and a heightened risk of side effects, such as Cushing’s syndrome and tremors. Other adverse effects might include a rapid or irregular heartbeat and adrenal gland issues.
  • Caffeine: Consuming caffeine while on Advair may heighten the risk of cardiac side effects. Both substances can cause a fast heart rate and palpitations, with their combined use possibly exacerbating these symptoms. Foods & beverages containing caffeine, like coffee, tea, energy drinks, cola, and chocolate, may need to be limited. Confirm with your doctor whether you should restrict your caffeine intake during Advair treatment.

[Note: This isn’t a complete list, and there could be other drugs that interact with (drug name). Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

What Are the Advair Diskus Alternatives?

People usually opt for alternative medicines due to varying Advair inhaler prices and when they don’t achieve the desired results. These factors influence patients to shift from their former treatment option to a different one. Several alternatives to Advair Diskus are available to help you treat asthma and COPD. Each of these medicines has its own set of active ingredients, mechanisms of action, and usage specifics. Here’s a list of some common alternatives:

• Symbicort (budesonide/formoterol)
• Breo Ellipta (fluticasone furoate/vilanterol)
• Dulera (mometasone/formoterol)
• Anoro Ellipta (umeclidinium/vilanterol)
• Wixela Inhub (fluticasone propionate/salmeterol)- Advair Diskus’s generic alternative
• AirDuo RespiClick (fluticasone propionate/salmeterol)
• Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol)
• Asmanex HFA (mometasone furoate)
• Flovent HFA (fluticasone propionate)
• Qvar RediHaler (beclomethasone dipropionate)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Advair Cost & Coupons

Handling the costs associated with Advair, which can significantly affect one’s budget, is essential as the price often surpasses $174 for an 8-gram supply. To cut costs, U.S. patients can buy Advair from Canadian online pharmacies, where it is generally more affordable. Polar Bear Meds, a reputable source, offers considerable discounts while buying Advair directly from Canada to the U.S. at an affordable price. As a new customer, you can use a discount coupon for Advair Diskus, “WELCOMEPB10,” to receive 10% off on your first order. Additionally, U.S. residents buying from Canada can further reduce costs by joining our referral program, which grants extra coupons for future purchases, making Advair more accessible.

Frequently Asked Questions

Is there a taste associated with taking Advair?

You may experience a taste of the medication after inhaling a dose of Advair. It’s important to rinse your mouth with water and spit it out after each dose, regardless of whether you tasted the medication. This practice helps lower the risk of developing yeast infections in your mouth and throat.

Is Advair effective for treating allergies?

Advair is not intended for treating allergies. The underlying causes and symptoms of allergies differ from those associated with asthma or COPD, so Advair is not effective in addressing allergy symptoms. If you have both asthma or COPD and allergies, you should discuss with your doctor the best options for managing your allergy symptoms.

Is long-term use of Advair (fluticasone/salmeterol) safe?

Advair (fluticasone/salmeterol) is generally safe for long-term use in controlling asthma or COPD symptoms, with many individuals using it without serious issues. Concerns about long-term steroid use, such as bone weakening and increased blood sugar, are more commonly associated with oral steroids rather than inhaled ones like fluticasone. For further questions regarding Advair’s long-term safety, consult your healthcare provider.

How quickly does Advair (fluticasone/salmeterol) start to work?

You may notice improvements in your breathing about 30 minutes after taking Advair (fluticasone/salmeterol). However, it might take a week or more to feel the full benefits. If your symptoms don’t improve significantly after two weeks, your healthcare provider may consider increasing the strength of the inhaler or exploring other medications.

Is Advair (fluticasone/salmeterol) safe to use during pregnancy?

The safety of Advair (fluticasone/salmeterol) during pregnancy is not well-established. Inhaled corticosteroids like fluticasone are typically preferred for treating asthma in pregnant women. Limited research suggests that LABAs like salmeterol, when used with an inhaled steroid, may not pose serious risks during pregnancy. If you’re pregnant or planning to become pregnant, it’s important to discuss the potential risks and benefits of using Advair with your healthcare provider, as uncontrolled asthma can pose risks to both you and your unborn baby.

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