Advair HFA

Advair Inhaler is a combination inhaler used for the long-term management of asthma and COPD, or chronic obstructive pulmonary disease. This prescription drug combines two active ingredients: fluticasone propionate, a corticosteroid that decreases inflammation in the airways, and salmeterol xinafoate, a long-acting bronchodilator that helps keep airways open. Available in Advair Diskus and Advair HFA, it is used every day to control symptoms and prevent flare-ups. It is important to note that it is not a rescue inhaler and does not provide fast relief for asthma attacks. Patients must follow their doctor’s guidance for dosage and proper use to maximize its benefits while minimizing side effects. If you want to buy Advair Inhaler online from Canada, use your doctor’s prescription.

The Advair Inhaler contains two active ingredients: fluticasone propionate & salmeterol. Fluticasone is a corticosteroid that lower inflammation in the airways, helping to prevent asthma attacks & COPD flare-ups. Salmeterol, a long-acting beta-agonist, helps relax the muscles around the airways, making breathing easier. Together, these ingredients control symptoms like wheezing and shortness of breath, improving lung function over time.

Advair is available in two common strengths: 100/50 mcg and 250/50 mcg. It is taken as a twice-daily inhaler, once in the morning and evening, using the inhaler. This medication is usually prescribed for adults and children aged 4 years and older with asthma or chronic obstructive pulmonary disease (COPD). Always follow the prescribed dosage to ensure effectiveness and avoid side effects.

Common side effects of Advair may include headaches, throat irritation, or an increased risk of respiratory infections. It’s important to follow the doctor’s advice regarding dosage and usage. If a dose is missed, take it as soon as possible, but skip the missed dose if it’s almost time for the next one. In case of an Advair overdose, seek medical attention immediately. Store it at a controlled room temperature, away from moisture and heat. Keep it out of reach of children, and always consult your medical giver for any concerns regarding its use.

It is used to treat:

• Asthma
• Chronic obstructive pulmonary disease

What Are the Forms & Strengths of Advair Inhaler?

It is available in the following forms and strengths:

Form: Advair Diskus

Strengths: 100 mcg fluticasone propionate / 50 mcg salmeterol

250 mcg fluticasone propionate / 50 mcg salmeterol

500 mcg fluticasone propionate / 50 mcg salmeterol

Form: Advair HFA

Strengths: 45 mcg fluticasone propionate / 21 mcg salmeterol

115 mcg fluticasone propionate / 21 mcg salmeterol

230 mcg fluticasone propionate / 21 mcg salmeterol

What Is the Typical Dosage of Advair Inhaler?

The recommended dosage of Advair Inhaler varies from individual to individual and is based on many factors, such as the patient’s age, condition, and tolerability. The dosage mentioned below applies to everyone, and if your doctor recommends a dosage different from the one given here, you should follow their instructions and not make changes to your dosage without consulting with them first. The usual recommended dosage includes:

For Preventing an Asthma Attack

Advair HFA

• Adults and children aged 12 years and above: Two puffs in the morning & two puffs in the evening. You should keep a gap of at least 12 hours between the two doses.
• Children under 12 years: Your doctor will determine the usage and dosage.

Advair Diskus

• Adults and children aged 12 years and above: Take 1 inhalation twice daily, with a gap of at least 12 hours between the two doses.
• Your doctor may alter the dosage if necessary. However, you should not take more than 500mcg of fluticasone and 50mcg of salmeterol twice daily.
• Children aged 4-11 years: 1 inhalation twice daily, once in the morning and once in the evening.
• Children less than 4 years of age: Your doctor should determine the usage and dosage.

For Treating and Preventing Attacks of COPD

• Adults: 1 inhalation twice daily, and you should ensure that the medication dosage is at least 12 hours apart. You should not use it more than twice each day.
• Children: Your doctor may determine the usage and dosage.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they will customize your dosage accordingly.]

• Before using an Advair Inhaler for the first time, each time you buy an Advair Inhaler refill online, read the patient information leaflet and medication guide given by your healthcare provider to ensure proper inhaler usage. Use it exactly as directed on the instruction sheets. If you have any questions or difficulty understanding any part of the leaflet, ask your physician or pharmacist.
• Use the Advair Inhaler exactly as your doctor directed. Do not use more or less of it, in large quantities, or more often, as it can cause unwanted side effects.
• Using too much Advair can lead to life-threatening symptoms.
• It is important to mention that Advair is not a rescue medicine. If you experience a COPD or asthma attack, use only a fast-acting inhaler and seek immediate medical assistance if your breathing problems worsen or if you think your asthma medicine is not working as efficiently as it should.
• Advair Diskus is available as a powder form of fluticasone & salmeterol with a special inhaler device pre-loaded with blister packs containing measured doses.
• Advair HFA is available in the form of a canister used with an actuator inhaler device.
• You should take this medicine at the same time each day to help you remember to take it. Use only the inhaler that came with your prescription.
• Before using the Advair HFA, shake it for at least five seconds.
• Do not let a child use an Advair inhaler without the supervision of an adult.
• You should properly rinse your mouth with plenty of water without swallowing after each use of the inhaler.
• You may require dosage alterations when your body is under stress due to surgery, illness, or a recent asthma attack. You should not make changes to your dosage without talking to your doctor first.
• If you are also using an oral steroid medicine after consulting with your doctor, do not stop using it abruptly. Follow your doctor’s directions on how to taper off the medicine gradually.
• If you also use a peak flow medicine at home, you should let your doctor know if your numbers are lower than usual.
• You may need to get your vision and bone mineral density to be checked more often.
• Once your asthma is under control, your doctor may want you to discontinue using the medicine. You should not discontinue using it unless your doctor tells you to.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They'll adjust it as needed over time.]

Advair Inhaler works by combining two active ingredients: fluticasone propionate and salmeterol, to help manage asthma & chronic obstructive pulmonary disease. Fluticasone is a corticosteroid that lowers inflammation in the airways, preventing swelling & irritation that can lead to breathing difficulties. Salmeterol, on the other hand, is a long-acting bronchodilator that helps ease the muscles around the airways, keeping them open for easier airflow. Together, these components work to control symptoms, improve lung function & decrease the frequency of exacerbations. Since Advair is a maintenance inhaler, it must be used consistently to be effective rather than as a quick-relief medication for sudden asthma attacks.

What Are the Side Effects of Advair Inhaler?

Common side effects of Advair Inhaler: Similar to other inhaled medicines, Advair is known to cause certain temporary side effects in some individuals using it. These symptoms do not usually require medical intervention and disappear within a few days or weeks as your body starts to adjust to the medicine. However, if these symptoms persist or become worse, tell your doctor or healthcare provider. These mainly include:

• Headache: Headaches are one of the most common side effects of Advair, potentially due to the body's adjustment to the medication or as a direct response to the inhaled components. To alleviate headaches, you can use over-the-counter pain relief medicines such as acetaminophen or ibuprofen, after consulting with your doctor. Ensure you follow the recommended dosages. If headaches persist or intensify, consult your healthcare provider for further evaluation. ​
• Muscle Pain, Bone Pain, and Back Pain: Musculoskeletal discomfort, including muscle aches, bone pain, and back pain, can occur with Advair usage. These pains may arise due to the body's response to corticosteroids like fluticasone, which can affect bone density over time. Engaging in regular weight-bearing exercises and ensuring adequate intake of calcium & vitamin D can help maintain bone health. If you have persistent or severe pain, seek medical intervention to assess bone density and discuss potential interventions.
• Nausea and Vomiting: Gastrointestinal issues including nausea and vomiting may be linked to Advair's components. These symptoms could result from the body's adjustment to the medication or irritation of the stomach lining. Taking Advair with food might reduce gastrointestinal discomfort. If nausea and vomiting continue or worsen, consult your healthcare provider for guidance. ​
• Thrush (Oral Candidiasis) and Throat Irritation: Fluticasone, a corticosteroid in Advair, can suppress local immune responses in the mouth, increasing the risk of fungal infections like thrush. To minimize this risk, rinse your mouth with water without swallowing after each dose. Persistent throat irritation or signs of thrush, such as white patches in the mouth, should be evaluated by a healthcare provider for appropriate asthma maintenance treatment. ​
• Ongoing Cough, Hoarseness, or Deepened Voice: Advair may cause throat irritation, causing a persistent cough, hoarseness, or changes in voice depth. These effects are typically due to irritation of the throat tissues. Rinsing your mouth after inhalation can help reduce throat irritation. If these symptoms become bothersome or interfere with daily activities, consult your medical provider for further evaluation. ​
• Cold Symptoms: Some individuals may experience upper respiratory tract symptoms, including stuffy nose, sneezing, and sore throat while using Advair. These symptoms could be related to the medication's effects on the respiratory tract or coincidental viral infections. If such symptoms persist or are severe, discuss them with your medical provider to determine appropriate management. ​
• Ear Infection in Children: In pediatric patients, Advair has been associated with an increased risk of ear infections. This may be due to the impact of corticosteroids on immune function. Regular monitoring by a medical provider is essential, and any signs of ear infection, such as ear pain or hearing difficulties, should prompt consultation with a paediatrician.

Severe side effects of Advair Inhaler: In rare cases, Advair is known to cause certain severe side effects in some users, especially those belonging to certain risk groups. These reactions require prompt emergency medical attention and can become life-threatening if not treated promptly. You should call your doctor or 911 if you experience any of these bothersome side effects. These mainly include:

• Respiratory Issues: Although rare, this medication can cause wheezing, choking, or other breathing problems. This can be due to paradoxical bronchospasm, where the airways constrict instead of dilating, causing breathing difficulties. If such symptoms occur, discontinue this medication and consult a medical provider immediately.
• Serious Infections: This medicine can increase your susceptibility to infections, including serious ones such as pneumonia and fungal infections. Its symptoms may include fever, chills, cough with mucus, and shortness of breath. To minimize this risk, rinse your mouth with plenty of water without swallowing after each dose and monitor for signs & symptoms of infection. If they do develop, seek immediate medical assistance.
• Cardiovascular Issues: Some patients may experience chest pain, irregular heartbeats, and tremors, which can result from salmeterol's action on heart rate and rhythm. Before using Advair, you should discuss any history of heart problems with your doctor.
• Vision Problems: Corticosteroids, including Advair, are known to cause eye issues in users. These mainly include blurred vision, seeing halos, or tunnel vision. To prevent this, you should visit your doctor on a regular basis, and if you experience any changes in vision, inform your doctor or healthcare provider immediately.
• Adrenal or Thyroid Problems: Long-term use of inhaled corticosteroids like fluticasone can affect adrenal and thyroid function. It may manifest itself as changes in blood sugar levels, dry mouth, and fruity breath odor. To manage and prevent this, you should regularly check your thyroid levels and blood sugar while being treated with Advair Inhaler. If you have any bothersome side effects, talk to your doctor.
• Electrolyte Imbalance: Leg cramps, constipation, irregular heartbeats, and sensations of fluttering in the chest can be signs of electrolyte imbalance. This medicine can influence potassium levels in the body, causing such symptoms. Ensure adequate potassium intake and consult a healthcare professional for regular monitoring of your symptoms.
• Growth Concerns in Children: Children using Advair may experience a slower growth rate. To minimise potential impacts, monitor growth regularly and use the lowest effective dose.
• General Symptoms: You may experience worsening fatigue, light-headedness, nausea & vomiting while being treated with this medicine. These may be associated with adrenal insufficiency or other systemic effects of corticosteroid use. If such symptoms persist or become worse, you should seek medical advice on an immediate basis.

[Note: Remember, the above list does not cover all potential side effects. Consult with your physician or healthcare giver for medical advice about side effects.]

• You should not use this medicine if you have ever had any allergic reaction to any of the ingredients present in this product, including fluticasone, salmeterol, or milk proteins. Tell your doctor immediately if you experience any signs & symptoms of a hypersensitivity reaction after taking Advair.
• Advair inhaler is not a rescue medicine, and it will not function as fast as a quick rescue inhaler to treat an asthma or bronchospasm attack.
• Get emergency medical attention immediately if you have breathing difficulties or if you think your medication may not be working as well as it should.
• Advair inhalers can cause fungal infections of the mouth and throat. To prevent these infections, rinse your mouth properly with plenty of water after inhaling. Advair is also associated with an increased risk of pneumonia in individuals with COPD.
• You should avoid being near people who have infections or are sick. If you think you may be exposed to measles or chickenpox, talk to your doctor as soon as possible for preventive treatment. These conditions can be fatal in people taking steroids.
• You should not use a second long-acting bronchodilator unless instructed by your doctor. This includes formoterol, arformoterol, olodaterol, salmeterol, or even vilanterol.

• Before using Advair Inhaler, let your doctor or healthcare provider know if you have ever had an allergic reaction to fluticasone or salmeterol. Also, tell them if you have a severe allergy to milk proteins or any other excipients or if you are currently having an asthma attack or COPD symptoms. You should be aware of all the ingredients present in this product, including active and inactive ones, as they can lead to unwanted reactions.
• Fluticasone, an active ingredient in Advair, can weaken your immune, making it easier for you to get an infection or worsen an existing infection. Tell your doctor about all the infections or illnesses you have had within the past weeks.
• Before using Advair Inhaler for the first time, share your medical or family history with your doctor or healthcare professional. Tell your doctor if you have or have ever had heart disease, hypertension, glaucoma, cataracts, a seizure, diabetes, a weak immune system, osteoporosis, chronic infections, a thyroid disorder, liver or kidney disease.
• Long-term use of steroids may cause osteoporosis, especially if you smoke, do not engage in physical exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis. Discuss your risk with your doctor.
• Let your doctor know if you are pregnant or think you may be pregnant. It is unknown whether Advair will cause harm to an unborn baby. However, having uncontrolled or untreated asthma while pregnant may cause complications, including low birth weight, premature birth, or dangerously high levels of blood pressure that can lead to medical problems in both mother and baby. The benefit of treating asthma may outweigh the risk to the unborn fetus.
• It is not unknown if fluticasone passes into breastmilk, but it is best recommended not to breastfeed while being treated with this medicine. Ask your doctor about any risks.
• You should not give this medicine to a child without medical advice.

Advair Inhaler may not be suitable for everyone. Do not use it if:

• You have ever had an allergic reaction to any of its ingredients, including fluticasone, salmeterol, or milk proteins.
• You have an ongoing asthma attack or severe COPD symptoms.

To get the most out of Advair Inaler, it is essential that you keep consistency in dosage and take it around the same time each day to help you remember to take it. If you have missed a dose, follow the instructions given below.

• If you have missed a dose of Advair inhaler, you should skip the missed dose and take your next dose according to the regular dosing schedule.
• You should not use double or extra doses of the same medicine to make up for the missed dose, as it can cause unwanted side effects.
• If you often forget to use a medicine dose at the scheduled time, you should set a medicine reminder on your mobile phone or mark your calendar to help you remember to use it.

[Note: If you have missed a dose of your medication and are not sure about when to take the next dose, consult your doctor or pharmacist immediately.]

If you think you or someone has taken Advair more than the prescribed dose or more often, it can lead to an overdose. Its symptoms may include fast heart rate, chest pain, feeling shaky, or shortness of breath. Seek medical assistance at once if you feel any of these symptoms. Call your doctor or 911. You can also go to the nearest medical care center.

[Note: If you consumed more than the recommended medication dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

Following proper storage guidelines is essential to make sure Advair Inhaler remains effective.

• Keep it at a controlled room temperature, away from direct exposure to sunlight, moisture & excess heat.
• Do not keep it in the bathroom or other places with high humidity. It can cause harm.
• Keep all medicines, including Advair inhalers, in their original packaging in a medicine cabinet, away from the sight and reach of children and pets.
• Do not keep medicines that are outdated or no longer required. Discard them safely so that no one can consume them.
• The best way to get rid of unwanted medicines is to take them to a medicine take-back program.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Certain medicines may interact with Advair inhalers and affect how they work. To prevent this, tell your doctor beforehand about all the medicines you are currently using or plan to use, including prescriptions, over-the-counter drugs, and herbs, or vitamins. These mainly include:

• Apalutamide
• Atazanavir
• Atenolol
• Carbamazepine
• Clarithromycin
• Cobicistat
• Conivaptan
• Darunavir
• Dextroamphetamine
• Fluconazole
• Idelalisib
• Indinavir
• Itraconazole
• Ketoconazole
• Labetalol
• Lisinopril
• Mavacamten
• Metoprolol
• Nelfinavir
• Nimodipine
• Posaconazole
• Ritonavir
• Saquinavir
• Sotalol
• Timolol
• Troleandomycin
• Voriconazole

What Are the Other Advair Inhaler Interactions?

You should avoid using certain medicines at or around the same time as eating food or using certain substances, as it can cause unwanted interactions to occur. If you are concerned about interactions of Advair with certain herbs, supplements, beverages, or eatables, discuss them with your doctor. If your doctor finds significant drug interactions, they may recommend you make certain lifestyle or dietary changes. The presence of certain medical conditions may also affect the use of Advair. Tell your doctor beforehand if you have or have ever had:

• Asthma
• COPD flare-up
• Bronchospasm
• Osteoporosis
• Diabetes
• Heart disease
• Glaucoma
• Arrhythmia
• Hypertension
• Hyperthyroidism
• Hypokalemia
• Ketoacidosis
• Seizures
• Chickenpox
• Stress
• Infections
• Liver disease
• Herpes simplex virus
• Measles

[Note: This isn't a complete list, and there could be other drugs that interact with Advair Inhaler. Tell your doctor about any prescription, over-the-counter medicines, and herbal products.]

There are many brand names and generic Advair alternatives available on the market. However, do not use them without first talking to your doctor. These mainly include:

• Albuterol (salbutamol)
• Symbicort (budesonide)
• Singulair (montelukast)
• Montelukast
• Budesonide
• ProAir HFA (albuterol)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

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