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We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More
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Select the prescribed dosage and quantity, then proceed to checkout.
Sign in or create a new account.
Upload your prescription.
Complete your purchase by processing the payment.
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Adapalene / Benzoyl peroxide is a topical acne medicine that combines two well-known and effective ingredients in just one product. Together, they are used to treat acne vulgaris in adults and children 9 years of age and older.
This gel contains Adapalene, a retinoid (vitamin A) present in a strength of 0.1%, and Benzoyl Peroxide (an antibacterial, skin peeling agent) present in a strength of 2.5%. It helps unclog pores, reduce inflammation, and kill acne-causing bacteria, which can lower the number and severity of pimples. This action also heals existing breakouts faster.
It does not “cure” acne, but when used regularly as directed and combined with a gentle skincare routine, it significantly improves acne over time. If you also want to order Adapalene / Benzoyl Peroxide online from Canada to get clearer, smoother skin, do so from trusted Canadian pharmacies.
| Generic Name | Adapalene / Benzoyl Peroxide |
|---|---|
| Brand Name | Epiduo |
| Forms | Gel |
| Strengths Available | 0.1% / 2.5% |
| Packaging | 70 g per pack |
| Requires Prescription | Prescription only (Rx) |
| Ships to the U.S. | Yes |
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In patients 9 years and older, Adapalene / Benzoyl Peroxide is used to treat:
Follow this step-by-step process on how to use Adapalene / Benzoyl Peroxide Gel correctly:
Step 1: Wash your hands before and after applying the gel.
Step 2: Wash the area that is affected with a gentle soap or cleanser. Rinse it well, then gently pat it dry.
Step 3: Apply a thin layer of Adapalene / Benzoyl Peroxide gel to all acne-prone areas. For example, forehead, cheeks, chin, chest, shoulders, or back.
Step 4: Spread it as you only need a small amount, not a thick coating (which may cause irritation).
Step 5: Rewash your hands.
Other important information:
Note: If anything is unclear to you, ask your doctor. Do not change the amount or duration on your own.
Adapalene / Benzoyl peroxide gel works together in a coordinated way to treat acne. It does so by targeting the main causes of breakouts at the same time.
Adapalene is a topical retinoid (a vitamin A-based molecule) that binds to retinoic acid receptors, which are proteins in the skin that control how skin cells grow and shed. It normalizes cell turnover inside the pores and prevents comedones (clogged pores). These actions reduce inflammation.
Benzoyl peroxide is both an antibacterial and a keratolytic agent. It releases oxygen that kills Cutibacterium acnes (the acne-causing bacteria) and lifts away excess oil and dead skin.
Common Adapalene / Benzoyl Peroxide side effects may include:
These effects often peak in the first 1 to 2 weeks and then improve as the skin adjusts to this medicine.
Serious side effects (rare):
There is no boxed (black-box) warning for adapalene/benzoyl peroxide gel, but beware of these other warnings:
If you forget to apply your Adapalene / Benzoyl Peroxide gel at your usual time, apply it as soon as you recall that same evening, as long as it is not almost time for your next routine dose. If it is, then skip the one you missed and resume with your once-daily dose regimen.
Do not apply extra gel or use it more than once a day to cover up, as this will not clear acne faster, but it will only increase irritation, redness and peeling.
Using much more Adapalene / Benzoyl Peroxide gel than prescribed, or if you apply it far more often. It may cause severe skin irritation, burning, redness, and significant peeling.
But it is unlikely to cause any life-threatening effects from skin use alone. If you or someone else has accidentally swallowed a large amount of this gel, it may cause severe reactions.
Call 911 or the Poison Control Center at their toll-free number 1-800-222-1222 for guidance. Do not try to treat yourself on your own if you suspect an overdose.
When you order Adapalene / Benzoyl Peroxide gel from Canada, store it correctly following these conditions:
As this gel contains two potent ingredients, it may interact with other topical skin products that may increase irritation or dryness. Tell your dermatologist if you are using any prescription, OTC (over-the-counter) products, cosmetics, or any other herbal supplements.
Here are some common alternatives that your dermatologist can prescribe to you instead of Adapalene / Benzoyl Peroxide gel:
At Polar Bear Meds, we’re committed to making prescription medications like Adapalene / Benzoyl Peroxide more accessible and affordable for patients in the U.S. Our prices are significantly lower than typical U.S. pharmacy retail rates without compromising on safety or quality. Every order is sourced exclusively from licensed and trusted pharmacies and undergoes complete prescription verification to ensure compliance and authenticity. We offer discreet, trackable shipping to all U.S. states, along with refill support for ongoing treatment. Our friendly customer service team is here to help you.
Get prescription acne gel from Canada to your doorstep in the U.S. You can also save more by using the Adapalene / Benzoyl Peroxide coupon code “WELCOMEPB10” for 10% off on your first order. There are no hidden handling or processing fees, as we believe in complete transparency. Looking to save even more? Join our referral program & earn a $20 credit every time you refer a friend or a family member. Your referral will also receive a $20 credit, so everyone wins. Additionally, after every 10 verified customers' referrals, you'll receive a $100 credit in your account as a thank-you for spreading the word.
At Polar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently buy Adapalene / Benzoyl Peroxide from Canada at a substantial cost, call us at 1-888-779-2193 toll-free.

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.
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