Polarbearmeds - Home
Amitriptyline Hydrochloride - Image 1

Amitriptyline Hydrochloride

No packages found
price-match-guarantee

Price Match Guarantee

We offer competitive pricing on all our medications. Find a lower price? We'll match it from any verified Canadian online pharmacy! Know More

Similar Medications

How to Order

Ordering your medication online is simple and convenient.

STEP 01

Select the prescribed dosage and quantity, then proceed to checkout.

STEP 02

Sign in or create a new account.

STEP 03

Upload your prescription.

STEP 04

Complete your purchase by processing the payment.

Shipping takes approximately 3-5 business days.

5 Star Excellence award from Shopper Approved for collecting at least 100 5 star reviews

Product Details

Description

Description

Amitriptyline hydrochloride is an FDA-approved medication that helps relieve symptoms of depression. This prescription drug belongs to the tricyclic antidepressants class of drugs that function by increasing the brain's chemical levels, like serotonin and norepinephrine. These increased levels improve depression. Amitriptyline is a generic drug that is available as an oral tablet in the market. Its strengths may vary from 10mg to 150mg. Therefore, it is important to talk to a medical expert. They will prescribe the tablet with a suitable strength according to the individual’s condition. Adults and older people can use this medication, but children below 12 years of age are not recommended to use Amitriptyline. However, like all medications, this drug has some risks associated with its use. Therefore, people are advised to always be aware of the potential warnings and safety precautions of the medication. For safe and efficient use, always buy Amitriptyline hydrochloride online from Canada.

Amitriptyline hydrochloride is a tricyclic antidepressant medication that is widely used to alleviate the symptoms related to depression. This generic drug works by balancing neurotransmitters, like serotonin & norepinephrine, in the brain, which helps improve mood and feelings of well-being. This medication is suitable for adults and children who are experiencing symptoms related to depression.

Amitriptyline is available in oral tablets with varying strengths ranging from 10 to 150mg. These tablets should be taken orally, once or thrice daily. Since it is a prescription drug, Amitriptyline must be used after consulting a medical professional. Do not share it with other individuals, even if they share the same condition, as it can increase the risk of side effects. If you plan to buy Amitriptyline hydrochloride online, talk to a medical expert for brief information on the medication. This prevents potential risks and side effects.

While it provides relief from depression symptoms, this medicine can lead to several side effects, such as dry mouth, dizziness, drowsiness, and increased appetite. Temporary effects like these are easy to manage as they eventually subside within a few days or weeks, but serious effects, such as allergic reactions, seizures, heart attack, and withdrawal symptoms, should not be overlooked. These side effects can result in life-threatening situations, so if you notice any such signs, report them immediately to a medical professional.

Uses and Benefits

Uses and Benefits

  • Amitriptyline is mainly used to relieve the symptoms associated with depression.
Dosage

Dosage

What Are the Forms & Strengths of Amitriptyline Hydrochloride?

Amitriptyline hydrochloride comes as an oral tablet with the following strengths:

  • 10mg
  • 25mg
  • 50mg
  • 75mg
  • 100mg
  • 150mg

What Is the Recommended Dosage for Amitriptyline Hydrochloride?

The following section includes only the average dosage recommendations. If you are considering Amitriptyline hydrochloride for depression management, talk to your doctor for an appropriate dosage regimen.

  • For Adults
    • Starting Dose: Take 75mg once a day in divided doses, or you can take 50-100mg at night.
  • Maximum Dose: 150mg each day.
    • For Children (12 to 17 Years)
    • Starting Dose: Take 10mg thrice a day with 20mg at bedtime. Ensure that the dose does not exceed 50mg a day.
  • Older Adults (Above 65 Years): Since the kidneys of older patients may not work as well as younger adults, the drug stays in their bodies for a long time. So, doctors may prescribe them a low starting dose or a different dosing schedule. This keeps the drug levels stable in their body.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they'll customize your dosage accordingly.]

Usage Guide

Usage Guide

To ensure safe administration of your medication, proper administration is a must. If you decide to buy Amitriptyline hydrochloride online, follow the below steps on how to take the medication correctly:

  • Firstly, read the medication guide & follow the guidelines that are mentioned on the label.
  • Do not take more or less doses unless your doctor advises otherwise.
  • Take the tablets by mouth, usually one to four times a day, with or without your food, as your doctor instructed.
  • Swallow the tablets with a glass of water.
  • Do not break, crush, split, or chew the medicine. Doing so may release the drug at once, increasing the risk of side effects.
  • If you are unable to swallow the tablet, talk to your doctor. They will suggest different options that suit your body’s needs.
  • Take the medication at the same time each day to get the best results.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They'll adjust it as needed over time.]

How It Works

How It Works

Amitriptyline hydrochloride works by increasing the levels of certain chemicals in the brain, like serotonin and norepinephrine. These chemicals play an important role in improving mood and relieving pain. When you take Amitriptyline, the drug blocks the reuptake of these chemicals into the presynaptic neuron, meaning more of them stay in the synaptic gap. This process provides relief from symptoms of depression and can also help with pain management.

Side Effects

Side Effects

What Are the Side Effects of Amitriptyline Hydrochloride?

Common Side Effects of Amitriptyline Hydrochloride: This medication can lead to several side effects. These effects are generally temporary and do not stay more than a few days or weeks. Such reactions occur during the first week of the treatment, which can be easily managed without needing immediate medical assistance. However, contact your doctor immediately if they become severe or persist over the mentioned period. Some of the common side effects of Amitriptyline hydrochloride include:

  • Confusion: This is a common side effect that occurs due to the drug’s impact on neurotransmitter levels in the brain. The increased levels of serotonin and norepinephrine can often result in cognitive disturbances. If you are experiencing this side effect, talk to your doctor.
  • Headache: Due to the medicine’s effects on blood vessels and neurotransmitters, users may experience headaches after taking their medication. This side effect generally occurs at the start of the treatment, and the pain may range from mild to moderate. To reduce the frequency of headaches, drink plenty of fluids, rest properly, and use over-the-counter pain relievers after consulting your doctor.
  • Blurred Vision: This side effect results from the anticholinergic properties of Amitriptyline, which can affect the muscles controlling eye movements and the fluid balance in the eyes. These temporary changes can be avoided if you take the correct dose. Watch out for any vision changes and report them to your doctor.
  • Skin Rash: This side effect occurs as an allergic reaction to Amitriptyline hydrochloride. If you are taking this medication, monitor for signs of rash and report them to your doctor.
  • Nausea: This drug can impact the gastrointestinal system, causing nausea in certain users. It is a temporary side effect that happens at the start of the treatment. To manage this effect, take the medicine with food, stay hydrated, and avoid heavy or spicy meals.
  • Sudden Weight Loss or Gain: Amitriptyline can affect digestion and metabolism, thus causing weight changes in users. People taking this drug should monitor their weight frequently and report any significant changes to a medical expert.
  • Dizziness: This is a common side effect that occurs due to fluctuations in blood pressure and balance. Users often experience this effect during the first week of the treatment. To avoid dizziness, avoid standing up suddenly from a sitting or lying position, stay hydrated & avoid drinking alcohol.
  • Dry Mouth: This medication can reduce saliva production due to its anticholinergic properties. It generally happens during the initial phase of the treatment and usually subsides within a few days or weeks. Till then, try chewing sugar-free gum, drink water frequently, and use saliva substitutes to prevent dry mouth.

Serious Side Effects of Amitriptyline Hydrochloride: Other than the common reactions, tricyclic antidepressants can cause certain severe side effects, which, if left untreated, can lead to life-threatening situations. If you experience any unusual signs during your treatment, seek immediate medical assistance. Some of the serious side effects of Amitriptyline hydrochloride may include:

  • Heart Attack: This drug can increase the chance of heart attack due to its effects on the cardiovascular system. As a result, users can experience changes in heart rhythm and blood pressure, leading to heart-related issues. If you notice any such signs, inform your doctor right away.
  • Seizures: This is a serious side effect that often as the medicine lowers the seizure threshold, making it easier for seizures to occur. The risk is higher in people with a history of epilepsy or other seizure disorders. Be alert of any unusual signs; if you notice any, talk to your doctor immediately.
  • High Blood Sugar: Amitriptyline can affect insulin sensitivity and glucose metabolism, causing high blood sugar levels. People with diabetes or those at risk of developing it should remain cautious while taking this medicine.
  • Suicidal Thoughts: This medication can increase the chance of suicidal thoughts & behaviors, especially in children, adolescents & young adults. It happens as the drug affects mood and mental health, resulting in increased suicidal ideation. People taking this medication should watch out for any changes in their mood or behavior and report them directly to a medical professional.
  • Orthostatic Hypotension: In this condition, users often experience a drop in blood pressure upon standing. This serious side effect can cause dizziness, lightheadedness, and fainting. Therefore, it is important to rise slowly from a sitting or lying position. If you notice any such symptoms, talk to your doctor right away.

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Warnings

Warnings

Yes, there are several warnings associated with the use of Amitriptyline hydrochloride. If you are considering treatment with Amitriptyline hydrochloride for sleep disorders or depression, be aware of the following warnings:

  • Withdrawal Symptoms: People using this medication for a long time should not stop the medication abruptly. Doing so may lead to withdrawal symptoms like nausea, headache, changes in sleep habits, and fatigue. In emergency situations, talk to your doctor to discontinue the medication in a short time. They will gradually lower your dose to prevent any unusual side effects.
  • Alcohol Interaction: Consuming beverages that contain alcohol while taking Amitriptyline can increase the risk of serious side effects, especially extreme drowsiness.
  • Allergy Warning: This medication can result in severe allergic reactions. If you develop any symptoms like skin rash, swelling on the face or tongue, and difficulty breathing during the treatment, seek immediate medical assistance.
  • Worsening of Depression: This drug may worsen depression, suicidal thoughts, and behavioral changes during the start of the treatment. The risk is higher until your body adjusts to the drug’s effects. If the condition does not persist, consult your doctor. They may lower the dose or suggest alternate treatment options.

What Are the FDA Boxed Warning for Amitriptyline Hydrochloride?

Amitriptyline hydrochloride carries a boxed warning that indicates that this medication can increase the risk of suicidal thoughts and behavior. Children, adolescents, and young adults are highly likely to experience these behaviors. People using Amitriptyline hydrochloride for depression management, regardless of their age, should closely monitor for any signs of changes in their behavior or if their depression is worsening.

Safety Guide

Safety Guide

When considering Amitriptyline hydrochloride for anxiety or depression management, you must be aware of its safety information to avoid the risk of potential side effects. Here are the precautions that you must take before or while using this medication:

  • If you are allergic to Elavil, Amitriptyline, or any of the ingredients present in the medication, inform your doctor beforehand. The product may contain certain components that can cause severe allergic reactions.
  • When considering treatment with this medication, share your complete medical history with your medical provider. This helps prevent the risk of any adverse reaction. This includes:
    • Glaucoma
    • Overactive thyroid
    • History of stroke
    • High blood pressure
    • Liver problems
    • Seizures
    • Bipolar disorders
    • Diabetes
    • Inability to empty your bladder
  • Before planning your surgery or undergoing other medical procedures, tell your medical professional about the products you use. This includes all prescription drugs, over-the-counter medications, or herbal supplements.
  • Do not use this medication if you just had a heart attack.
  • Children under 12 years of age should not use this medication.
  • Amitriptyline can affect alertness or coordination. Therefore, users are advised to avoid driving, using machines, or doing activities that require alertness.
  • Amitriptyline can cause photosensitivity. In this condition, your skin may become sensitive to sunlight, sunlamps, and tanning beds. So, people using this medication should avoid sun exposure, as it can cause severe blisters, sunburn, or swelling. If it is necessary to go out, use sunscreen or wear protective clothing.
  • It is unknown whether this drug harms unborn babies. So, if you are pregnant or planning to get pregnant, talk to your doctor. Discuss every risk & benefit associated with the use of this medication.
  • Amitriptyline hydrochloride can pass into breast milk. If you are a breastfeeding mother, talk to your doctor before using this drug. They will advise you if you should discontinue breastfeeding or stop using the medication.
Contraindications

Contraindications

Do not take this medication if you have the following conditions or problems:

  • Hypersensitivity reaction to Amitriptyline hydrochloride or any of the medication’s ingredients:
    • Heart problem
    • Blood disorder (porphyria)
    • Liver problems
    • Epilepsy
    • Glaucoma
    • Suicidal thoughts
    • Diabetes
Missed Dose

Missed Dose

  • If you are taking Amitriptyline once a day and forget a dose, skip the missed dose and continue following the usual dosing schedule.
  • However, if you are taking the medication twice or thrice daily and forget a dose, take the missed one as soon as possible unless it is almost time for your next dose.
  • Remember not to take two doses simultaneously, as this can increase the risk of side effects.
  • Use medication apps or set timers on your mobile devices to avoid skipping any doses.

[Note: If you have missed a dose of your medication and are unsure about when to take the next one, immediately consult your doctor or pharmacist.]

Overdose

Overdose

Yes, taking more than the recommended dose of Amitriptyline can cause harmful effects due to significantly high levels of the drug in the body. If you are experiencing any of the following overdose symptoms, seek immediate medical assistance or call 911. These symptoms may include:

  • Convulsions
  • Hallucinations
  • Confusion
  • Stiff muscles
  • Irregular heart rhythm

[Note: If you consumed more than the recommended dose, get medical help right away or call the Poison Help line at 1-800-222-1222.]

Storage Guide

Storage Guide

A controlled environment is necessary to maintain the long-term effectiveness of every medication. If you are using Amitriptyline hydrochloride for sleep disorders or depression, follow the below storage guidelines:

  • Store the medication at a normal temperature between 20°C and 25°C. The medication can also be kept between 15°C and 30°C for a brief period, especially when traveling.
  • Keep the tablets in their package to protect them from heat and moisture.
  • Store the medicine away from reach and out of sight of children.
  • Discard the medication when it is not in use or reaches its expiry date.
  • Ask a medical expert how to safely dispose of the product without damaging the environment.

[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]

Interactions

Interactions

If you are using Amitriptyline hydrochloride for depression management, avoid combining two or more drugs with this medication. Doing so can result in drug interaction, which can reduce the effectiveness of the drugs & increase the risk of side effects. Therefore, if you are considering using this medication, be aware of the following drugs as they may cause drug interactions:

  • Cisapride
  • Clorgyline
  • Dronedarone
  • Furazolidone
  • Grepafloxacin
  • Iproniazid
  • Isocarboxazid
  • Almotriptan
  • Astemizole
  • Atazanavir
  • Azimilide
  • Bromfenac
  • Brompheniramine
  • Bufexamac
  • Buprenorphine
  • Bethanidine
  • Cimetidine
  • Desogestrel
  • Diazepam
  • Dicumarol
  • Dienogest
  • Drospirenone
  • Ethinyl Estradiol
  • Ethynodiol
  • Fosphenytoin
  • Galantamine
  • Gestodene
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Toloxatone
  • Tranylcypromine
  • Ziprasidone

What Are the Other Amitriptyline Hydrochloride Interactions?

Taking Amitriptyline hydrochloride while having the following medical conditions can result in certain interactions:

  • Anticholinergic effects
  • Cardiovascular disease
  • Pheochromocytoma
  • Acute myocardial infarction recovery
  • Cardiovascular disease
  • Seizure disorders
  • Bone marrow suppression
  • Diabetes
  • Renal/liver disease
  • Schizophrenia/bipolar disorder
  • Tardive dyskinesia
  • Acute alcohol intoxication
  • Bipolar disorder screening
  • Glaucoma
  • Hyper/hypoglycemia
  • Liver/renal disease
  • Neutropenia
  • Schizophrenia
  • Thyroid disorders
  • Urinary retention

[Note: This isn't a complete list, and there could be other drugs that interact with Amitriptyline Hydrochloride. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Alternatives

Alternatives

People often choose drug alternatives when they are not getting the desired results or the medication is not suitable due to certain medical conditions. Drug alternatives provide them with a convenient way to switch from one treatment option to another. However, users are advised to always consult a medical professional before making any decision, as many drugs are available in the market. Your doctor may examine your condition and determine the most suitable alternative for you. Here are some popular drugs that you can take in place of Amitriptyline hydrochloride for sleep disorders and depression:

  • Celexa (citalopram)
  • Cyclobenzaprine
  • Cymbalta (duloxetine)
  • Effexor (venlafaxine)
  • Pamelor (nortriptyline)
  • Remeron (mirtazapine)
  • Wellbutrin (bupropion)

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

Cost & Coupons

Cost & Coupons

Amitriptyline hydrochloride is an effective tricyclic antidepressant, but it is not affordable for every individual due to its high retail prices. At Polar Bear Meds, we understand this concern; that’s why we offer affordable medications across the USA to make them accessible to every customer without any healthcare insurance plans. We also provide cost-saving coupons that buyers can use at the checkout using code “WELCOMEPB10” and get 10% off on their first order. Do not sit back; take advantage of this opportunity and buy Amitriptyline hydrochloride for anxiety and sleep disorders delivered to your doorstep directly from Canada.

FAQ

FAQ

Guarantee

Guarantee

AtPolarBearMeds.com, we assure you the most affordable price to buy Amitriptyline Hydrochloride. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently buy Amitriptyline hydrochloride for anxiety or depression at a substantial cost, call us at 1-888-779-2193 toll-free.

Important Notice

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Learn more about Amitriptyline Hydrochloride and related topics

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn
Price matching guarantee certificate

We offer competitive pricing on all our medications. We'll match if you find a lower price on an identical product at a verified Canadian online pharmacy!

Eligibility Criteria:

  • The competitor's price must be active (no past/future sales).
  • It is only valid for Canadian online pharmacies with a verifiable address.
  • The product must match the strength, pack size, quantity, manufacturer & origin.
  • There are no price matches on used/expired medications.
  • You must submit your requests before placing an order.
  • We cannot adjust prices after purchase.
  • Request via live chat or phone before placing your order.

Need help? Call our friendly support team at 1-888-779-2193 or fill out the Contact Form