Budesonide

Budez CR

Budez CR, an FDA-approved medication, contains Budesonide and is utilized to manage inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease by decreasing inflammation in the digestive tract. Presented in controlled-release capsules with strength 3 mg., it’s taken orally once daily, preferably in the morning, with or without food. Suitable for adults and children over 8 requiring maintenance therapy, it’s generally well-tolerated, with possible side effects including headache and abdominal discomfort. Patients should promptly report severe or persistent side effects and be mindful of potential drug interactions. If a dose is missed, patients should take it as soon as remembered, but doubling up is not advised. Storage should be at room temperature, away from moisture and heat. Compliance with prescribed dosages is essential, with any dose adjustments requiring consultation with a healthcare provider.

Product Overview

Budez CR is a prescription medication approved by the FDA, containing the active ingredient Budesonide. It primarily treats inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis. Budesonide, a corticosteroid, works by decreasing inflammation in the digestive tract, thereby alleviating symptoms such as abdominal pain, diarrhea, and rectal bleeding. Available in controlled-release capsules, it comes in a strength of 3 mg. The recommended dosage and duration of treatment are determined by the severity of the condition and individual response to the medication. It is usually taken orally once daily, preferably in the morning, with or without food. Budez CR is suitable for adults and children over the age of 8 who require maintenance therapy for their inflammatory bowel disease.

While Budez CR is generally well-tolerated, some individuals may experience side effects such as headache, nausea, abdominal discomfort, or changes in appetite. Following the healthcare provider’s advice and reporting any persistent or severe side effects is important. Patients should also be cautious regarding potential drug interactions and disclose all medications they are currently taking.

In case of a missed dose, patients should take it as soon as they remember unless it is almost time for the next dose. However, doubling the dose to catch up is not recommended. Immediately seek medical attention if there is a suspicion of an overdose. Store Budez CR at room temperature away from moisture and heat, and keep it away from children. Avoid exceeding the recommended dosage without conferring with your healthcare provider.

Uses of Budez CR

• It is used for the treatment of Crohn’s disease and ulcerative colitis.

How to Use Budez CR?

Dosage

It comes it the form of Controlled-release capsules and has a strength of 3 mg

Recommended Dosage for Different Patients

For Adults with Crohn’s Disease – Acute

• Taking 9 mg of the capsules once daily for 8 weeks, taken in the morning, is recommended.

For Adults with Crohn’s Disease – Maintenance

• Taking 6 mg once daily in the morning for at least 3 months is recommended. Once symptoms have been controlled for three months, taper the dose to complete cessation.

For Adults with Ulcerative Colitis

• Initially, it is recommended to take 9 mg once daily in the morning. The treatment duration is up to 8 weeks.

For Pediatric Patients with Crohn’s Disease – Acute

• For up to 8 weeks, take 9 mg orally once daily in the morning, then 6 mg once daily for two weeks.

For Pediatric Patients with Crohn’s Disease – Maintenance

• It is recommended to take 1 mg once daily or 0.5 mg twice daily.
• The maximum daily dose is 1 mg.

[Note: These Budez CR dosage recommendations may differ from individual to individual. Discuss it with your healthcare professional, and they’ll decide your dosage accordingly.]

How to Take It?

• Take Budez CR capsules orally once daily.
• Ideally, take it during the morning hours.
• It can be ingested with or without food.
• Consume the controlled-release capsules whole with water.
• Refrain from Crushing, splitting, or chewing the capsules.
• Seek advice from a healthcare provider if swallowing becomes challenging.
• Adhere to the healthcare provider’s guidance on dosage and timing.
• Avoid discontinuing Budez CR suddenly without consulting a healthcare provider.
• Abrupt cessation might result in exacerbated symptoms or withdrawal symptoms.

[Note: Your healthcare professional will decide the correct amount of Budez CR for you based on your condition. They may adjust your Budez CR dosage as needed over time.]

How Does Budez CR Work?

Budez CR contains Budesonide, a corticosteroid that reduces intestinal inflammation, which helps alleviate symptoms such as abdominal pain, diarrhea, and rectal bleeding. Budez CR exerts its effects by inhibiting the production of certain chemicals in the body that trigger inflammation. Its controlled-release formulation ensures a steady release of the medication over time, providing prolonged relief from symptoms and minimizing potential side effects.

Important Safety Information

Side Effects

Common side effects of Budez CR may include:

• Headache
• Nausea
• Abdominal pain
• Indigestion
• Diarrhea
• Dizziness
• Fatigue
• Upper respiratory tract infections

Mild side effects of Budez CR may include:

• Throat irritation
• Cough
• Runny or stuffy nose
• Muscle or joint pain
• Changes in taste sensation

Adverse side effects of Budez CR may include:

• Allergic reactions (redness, irritation, inflammation of the face, throat, or tongue)
• Severe abdominal pain or Cramping
• Bloody or black stools
• Unusual tiredness or weakness
• Vision changes
• Mood changes ( depression or anxiety)
• High blood pressure
• Increased susceptibility to infections
• Difficulty sleeping (insomnia)

[Note: This list may not cover all possible Budez CR side effects. Always discuss with your healthcare giver for medical advice about side effects.]

Warnings

• Infections: Corticosteroids like Budez CR may increase susceptibility to bacterial, viral, fungal, or parasitic infections. Patients should avoid contact with contagious individuals and promptly report the infection signs to their healthcare professional.
• Immunosuppression: Prolonged use of corticosteroids may suppress the immune system, leading to infections and delayed wound healing. Patients should be monitored for signs of immunosuppression, and vaccination may be recommended before starting treatment with Budez CR.
• Adrenal Suppression: Insufficient adrenal function can result from long-term use of corticosteroids, leading to adrenal insufficiency. Abrupt discontinuation of Budez CR after prolonged therapy should be avoided, and gradual tapering under medical supervision may be necessary to prevent adrenal Crisis.
• Glucocorticoid Withdrawal: Abrupt discontinuation of corticosteroid therapy may result in glucocorticoid withdrawal symptoms, including fatigue, muscle pain, joint pain, and fever. Patients should be gradually tapered off Budez CR to minimize the risk of withdrawal symptoms.
• Gastrointestinal Effects: Budez CR may cause gastrointestinal adverse effects, for example, stomach pain, nausea, and diarrhea. Those having a history of peptic ulcer disease or gastrointestinal bleeding should be monitored closely for worsening symptoms.
• Bone Health: Long-term use of corticosteroids can result in bone loss and a raised risk of osteoporosis. Patients on prolonged therapy with Budez CR should be monitored for bone density and may require supplementation with calcium and vitamin D or other osteoporosis medications.
• Psychiatric Effects: Corticosteroids may cause psychiatric adverse effects, including mood swings, depression, anxiety, and psychotic reactions. Patients should be regularly monitored for mood changes or behavior while taking Budez CR.
• Glucose Intolerance: Budez CR may cause glucose intolerance or exacerbate diabetes mellitus. Blood sugar levels should be monitored in patients having diabetes or at risk of developing diabetes while on corticosteroid therapy.
• Eye Health: Prolonged use of corticosteroids may increase the risk of cataracts and glaucoma. Patients should undergo regular eye examinations while on treatment with Budez CR.

Precautions

• Follow your doctor’s instructions precisely. Only adjust the dosage or discontinue Budez CR after consulting your doctor first.
• Attend all follow-up appointments and tests as directed.
• Keeping a distance from sick individuals reduces the risk of infection.
• Inform all healthcare providers about your Budez CR use.
• Monitor for side effects like nausea or mood changes and report them promptly.
• Maintain bone health with sufficient calcium and vitamin D intake.
• Monitor eye health for conditions like cataracts or glaucoma.
• If you have diabetes, you should closely monitor your blood glucose levels.
• Drinking too much alcohol can lead to side effects.
• Inform your healthcare professional if you are pregnant or breastfeeding.

Budez CR Contraindications

• Budez CR should not be used in patients with uncontrolled acute infections.
• Avoid Budez CR if you have a known hypersensitivity to Budesonide.
• It is not recommended during lactation.

Missed Dose

• If you forget to take a dose of Budez CR, take it when you recall.
• Take your next dose if it’s near. Follow your regular schedule instead.
• Avoid taking two doses at once to compensate for the missed one.
• Ensure you maintain a regular dosing routine for the medication to work effectively.

[Note: If you have missed a dose of Budez CR and are still deciding when to take the next dose, immediately consult your doctor or pharmacist.]

Overdose

Symptoms of overdose may include nausea, vomiting, headache, dizziness, fainting, weakness, fatigue, increased thirst or urination, confusion, seizures, and difficulty breathing. Do not attempt to manage an overdose on your own.

[Note: If you overdosed on Budez CR, get medical help instantly or call the Poison Help line at 1-800-222-1222.]

Storage

• Store Budez CR at room temperature, shielding it from moisture, heat, and light.
• Ensure the medication remains in its original container, tightly sealed.
• Avoid freezing Budez CR.
• Keep it inaccessible to children and pets.
• Refrain from storing Budez CR in moisture-prone areas, such as bathrooms or near sinks.

[Note: Consult with your healthcare practitioner about the proper disposal of unused Budez CR and any questions you may have regarding their storage.]

Budez CR Interactions

Here are some drugs that may interact with Budez CR:

• Ketoconazole
• Itraconazole
• Ritonavir
• Indinavir
• Nelfinavir
• Erythromycin
• Clarithromycin
• Telaprevir
• Boceprevir
• Rifampin
• Phenobarbital
• Phenytoin
• Carbamazepine
• St. John’s Wort
• Warfarin
• Cyclosporine
• TaCrolimus
• Sirolimus
• Everolimus
• Rifabutin

[Note: This list is not complete, and Budez CR may interact with other drugs. If you take prescription, over-the-counter, or herbal medicines, tell your doctor about them.]

Budez CR Alternatives

• Entocort (budesonide)
• Uceris (budesonide)
• Cortiment (budesonide)
• Pulmicort (budesonide)
• Rhinocort Aqua (budesonide)
• Budenofalk (budesonide)
• Symbicort (budesonide/formoterol)
• Budate (budesonide)
• Budicort (budesonide)

[Note: Your healthcare professional will select the best Budez CR alternative. You should discuss this with your healthcare professional before using these alternative medications. You may experience serious side effects if you take them on your own. 

Frequently Asked Questions

Is the Budez CR capsule effective?

Budez CR Capsule is effective for treating moderate to severe ulcerative colitis. It belongs to a group of medicines called steroids and helps relieve pain and inflammation caused by the condition. Common side effects such as respiratory infection, headache, back pain, nausea, dizziness, flatulence, and indigestion may occur. Remember to take it as prescribed by your doctor for maximum benefits!

Can I stop taking the Budez CR capsule if I feel better?

Even if you observe an improvement in your condition, do not stop using Budez CR Capsule without consulting your doctor. If you discontinue the use of Budez CR Capsule immediately, your symptoms may relapse. Following your doctor’s guidance is essential to ensure the best outcome.

Are Budez CR capsules safe for children?

Budez CR Capsule is not recommended for use in children below 12 years of age unless prescribed by a doctor. If you have concerns about your child’s health, please consult a healthcare professional. 

Can the Budez CR capsule cause bone loss?

Yes, if you use Budez CR Capsule for an extended period, it may lead to osteoporosis and glaucoma. Regular bone density tests and eye pressure checks are advisable while taking this medication. Always consult your doctor before making any changes to your treatment plan. 

Is the Budez CR capsule harmful to the immune system?

Yes, the Budez CR may weaken your immune system, especially when taken orally. Using this medicine with caution and under your doctor’s supervision to minimize the risk of secondary infections is essential.

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