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Empagliflozin
Jardiance
Jardiance (empagliflozin) is an FDA-approved prescription medication used to control high blood sugar levels in patients with type 2 diabetes. It also helps prevent the severe complications associated with diabetes. It contains empagliflozin, an orally active inhibitor of the SGLT2 class. It is used alone or with other medicines to treat the condition. It is used alongside a proper diet and exercise plan. It is available as an oral prescription medicine that comes in two doses, 10 mg and 25 mg, to be taken every morning, with or without food. Your doctor will decide the proper dosage for you based on your medical condition and response to treatment.
Product Overview
Jardiance is an FDA-approved prescription medicine containing the active ingredient empagliflozin. It is used to control high blood sugar levels in adults and children over ten years of age with type 2 diabetes. Empagliflozin works by increasing the removal of sugar and sodium by the kidneys, thereby reducing blood sugar levels and the risk of complications such as kidney damage, nerve problems, and cardiovascular disease.
Jardiance is available in two strengths: 10 mg and 25 mg daily. It is taken orally once a day, preferably in the morning, with or without food. The initial dosage is typically 10 mg, which may be increased to 25 mg based on the patient’s response to treatment and glycemic control needs.
Common side effects of Jardiance include vaginal infections, urinary tract infections, and dehydration. It is essential to consult your doctor if you experience adverse side effects such as little or no urination, signs of dehydration, or symptoms of bladder infection. Jardiance should be used with caution in pregnant or breastfeeding women and is contraindicated in patients with severe renal impairment, end-stage renal disease, or a history of hypersensitivity to empagliflozin. In case of a missed dose, take it as soon as possible, but skip it if the next dose is near. For overdose, seek immediate medical attention. Store Jardiance at room temperature, away from heat, light, and moisture, and keep it out of reach of children and pets. Always follow your healthcare provider’s instructions for proper usage and dosage.
What Are the Uses of Jardiance?
Jardiance is used to:
- Control high blood sugar levels in type 2 patients.
- Reduce the risk of hospitalization and death due to heart failure, cardiovascular disease, and stroke.
What Are the Forms & Strengths of Jardiance?
Dosage
It comes in the form of an oral tablet. It is available in two strengths:
- Jardiance 10 mg tablets
- Jardiance 25 mg tablets
What Are the Recommended Jardiance Doses for Different Patients?
The recommended dosage of Jardiance can vary depending on the patient’s condition, but here are some general guidelines:
For Adult Patients With Type 2 Diabetes
- Initially Dose: 10 mg daily
- The dose will be increased once the patient tolerates therapy and needs additional glycemic control.
For Adult Patients For Cardiovascular Risk Reduction
- Recommended Dose: 10 mg daily
For Adult Patients With Chronic Kidney Disease
- Recommended Dose: 10 mg daily
[Note: Remember these recommendations may vary depending on person to person. Discuss it with your doctor, and they’ll customize your dosage accordingly.]
How to Use Jardiance?
Before you start taking Jardiance, make sure to read the patient information and instructions carefully. This will help you understand how the medication should be used.
- Take Jardiance by mouth, either with or without food.
- The recommended time to take Jardiance is in the morning.
- Your doctor will decide the proper dosage for you based on your medical condition and response to treatment.
- It’s important to take Jardiance regularly to get the most benefit from it. Try to take it at the same time each day.
Remember, always follow your doctor’s instructions when taking Jardiance. If you have any questions or need further clarification, don’t hesitate to ask your doctor or pharmacist.
[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]
How Does Jardiance Work?
Jardiance 10 mg tablet is an antidiabetic prescription medicine that reduces blood sugar levels by increasing the removal of sugar by your kidneys and excretes all excess glucose through urine. SGLT2 inhibitors effectively lower the hB1AC levels and help regulate weight loss and blood pressure. They also help prevent chronic kidney disease by reducing the reabsorption of the excess sugar and sodium from the kidney, hence protecting it.
Important Safety Information
What Are the Side Effects of Jardiance?
When you take a Jardiance 10 mg tablet, it may cause common side effects. This includes:
- Urinating More Frequently Than Usual: This side effect arises because Jardiance works primarily by helping the kidneys flush out glucose through urine. As a result, the increased glucose in the urine pulls more water into the bladder, leading to a higher frequency of urination. This mechanism is intended to help control blood sugar levels in individuals with diabetes but can lead to a number of trips to the bathroom.
- Mild Urinary Tract Infection (UTI): Users of Jardiance may experience mild urinary tract infections. This is possibly due to the increased amount of sugar in the urine, which can foster the growth of bacteria. These bacteria can invade the urinary tract, leading to infections that often cause a burning sensation during urination, a need to urinate more often, and sometimes pelvic pain.
- Producing More Urine Than Usual: Similar to urinating more frequently, producing more urine directly results from the drug’s action on the kidneys. Jardiance increases the elimination of sugar from the bloodstream via the urine. When sugar is expelled, it carries water along with it, thus increasing the overall volume of urine produced.
- Mild Fungal Infection of the Male Genitals: Men taking Jardiance may be at a higher risk of developing fungal infections around the genital area. This is due to the increased glucose levels in the urine, which may create an environment that supports fungal growth, especially in warm, moist areas like the genitals.
- Mild Vaginal Yeast Infection: Similar to fungal infections in males, women may experience mild vaginal yeast infections while taking Jardiance. The presence of increased levels of glucose in the urine can also affect the vaginal area, leading to the growth of yeast. This can lead to signs such as itching, irritation, and discharge.
Although not so common, Jardiance can cause several mild side effects, including:
- Joint pain: Some individuals taking Jardiance report experiencing joint pain. While not directly linked to the medication’s primary mechanisms, this discomfort may arise as a side effect of changes in body fluid levels and electrolyte imbalances.
- Excessive thirst: As a side effect of Jardiance, excessive thirst can occur due to the body’s loss of fluids through increased urination. This condition, known as polydipsia, prompts an increased intake of fluids to compensate for dehydration.
- Nausea: Nausea can occasionally occur as a side effect of Jardiance. This feeling of stomach discomfort and the urge to vomit might be linked to the body’s adjustment to the medication or its effects on blood sugar levels.
- Mild allergic reaction: An allergic reaction to Jardiance may lead as skin rashes, itching, or mild swelling. These reactions are relatively uncommon and generally not severe but should be monitored and reported to a healthcare provider.
When you buy Jardiance online, you can consider the serious side effects related to this medication:
- Severe Allergic Reaction: Jardiance may cause severe allergic reactions in some individuals. These reactions can include symptoms such as swelling of the lips, face, and throat, which can impede breathing and require immediate medical attention. Rash, itching, and hives are also common signs of a severe allergic response.
- Hypoglycemia (Low Blood Sugar): While hypoglycemia is less frequent with SGLT2 inhibitors like Jardiance, it can still occur, particularly when combined with other diabetes medications that raise insulin levels. Symptoms of low blood sugar levels may include sweating, shaking, confusion, blurred vision, and slurred speech. It is essential for individuals taking this medication to monitor their blood sugar levels regularly.
- High Cholesterol: Jardiance has been associated with increases in cholesterol levels in some patients. This side effect necessitates monitoring blood lipid levels during treatment, as high cholesterol is a risk factor for cardiovascular diseases. Patients may need to manage this risk through diet, lifestyle changes, or medication.
- Diabetic Ketoacidosis: A rare but severe side effect of Jardiance is diabetic ketoacidosis, a condition where higher levels of ketones build up in the blood, making it acidic. It can occur even if blood sugar levels are not very high. Symptoms include nausea, vomiting, abdominal pain, tiredness, and trouble breathing and require immediate medical treatment.
- Dehydration: Jardiance can cause dehydration and a decrease in blood volume, leading to symptoms such as dizziness, fainting, and low blood pressure, particularly in the elderly and those with existing kidney problems. It is important for patients to stay hydrated and monitor for signs of dehydration.
- Severe Hypotension (Low Blood Pressure): The diuretic effect of Jardiance may lead to severe hypotension, especially in patients who are elderly, are on diuretics, or have reduced kidney function. Symptoms include dizziness, lightheadedness, and fainting, which can increase the risk of falls & related injuries.
- Kidney Problems: Jardiance can affect kidney function, leading to serious kidney issues, including acute kidney injury. Regular monitoring of a kidney’s function is recommended for all patients taking this medication, as the risks are higher in those with pre-existing kidney disease or severe heart failure.
- Severe Infection in the Perineum (Fournier’s Gangrene): Though rare, patients taking Jardiance have reported severe infections in the perineum, known as Fournier’s gangrene. This serious bacterial infection requires immediate medical attention and often surgical intervention, as it can be life-threatening.
- Severe Urinary Tract Infection: Jardiance can lead to severe urinary tract infections (UTIs). Symptoms can include painful urination, an urgent need to urinate frequently, fever, and pain in the lower abdomen.
[Note: This list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]
What Are the Jardiance Warnings?
Consult your doctor and discuss all your disease-related or medication-related queries. You can also refer to the medication guide to learn more about the warnings if you have severe symptoms like stomach pain, vomiting, fatigue, or difficulty breathing. Contact your doctor and seek medical attention immediately. Jardiance can also cause serious infections in the genital area. Contact your doctor if you have severe redness, itching, burning, or rashes in such areas.
What Are the Jardiance Precautions?
It is essential to inform your doctor and pharmacist if you:
- Have any allergies to Jardiance.
- Are taking Other prescription and non-prescription medications currently, especially if you take any other diabetes medicine.
- Have a medical history, especially if you have ever had high cholesterol, liver problems, kidney problems, dehydration, low blood pressure, heart failure, or a history of yeast infections in the vagina or penis.
- Have any history of alcohol abuse.
Additionally, be aware of the following:
- Low or high blood sugar levels can cause blurred vision, dizziness, or drowsiness. It is essential to avoid driving, operating machinery, or any other activities that require clear vision or alertness.
- Drinking alcohol while taking Jardiance may increase the risk of developing low blood sugar. It is recommended to limit alcohol intake while taking this medication.
- Older adults may be more sensitive to the side effects of Jardiance. It is crucial for older adults to closely monitor their condition and inform their doctor if they experience any unusual symptoms.
- During pregnancy, Jardiance should only be used when needed. It is essential to consult with a healthcare professional before using this medication during pregnancy.
What Are Jardiance Contraindications?
Jardiance is contraindicated in patients who have:
- Allergy to Jardiance or any of its active ingredients
- History of hypersensitivity to empagliflozin and any inactive ingredients
- Severe renal impairment
- End-stage renal disease
- Undergoing dialysis
What Happens If You Miss a Dose of Jardiance?
Missing a dose of Jardiance can be managed easily. You need to follow these guidelines in case of a missing dose:
- If you miss a dose, take it as soon as you remember.
- If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- For the best results, take your medicines regularly.
- Do not take two doses together to compensate for the missed dose.
[Note: If you have missed a dose of Jardiance and are still determining when to take the next one, immediately consult your doctor or pharmacist.]
Overdose: What Happens If You Take Too Much Jardiance?
If someone has passed out or has serious symptoms of an overdose like difficulty breathing, severe nausea, or infection, seek immediate emergency medical attention.
[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]
Storage: How Do You Store Jardiance?
Jardiance (empagliflozin) should be stored in a safe and appropriate manner to maintain its effectiveness. Here are general guidelines for storing Jardiance:
- You may keep Jardiance at room temperature.
- Make sure to store it away from children’s reach.
- Additionally, it is important to note that heat, air, light, and moisture can damage your medicine.
- Store the medicine in a cool and dry place.
[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]
What Are the Jardiance Interactions?
It’s crucial to inform your healthcare provider about all medications, supplements, and herbal products you are taking before starting Jardiance. They can assess potential drug interactions and adjust your treatment plan accordingly to ensure your safety and the effectiveness of the medication. Here are some notable drug interactions with Jardiance tablet:
- Combining Jardiance with insulin or insulin-secretagogues (like, sulfonylureas like glipizide or glyburide) can elevate the risk of hypoglycemia (low blood sugar).
- Some diabetes medications, such as DPP-4 inhibitors (such as sitagliptin) or GLP-1 receptor agonists (like exenatide), may interact with Jardiance. Your doctor will consider these interactions when determining your treatment plan.
- Combining it with other diuretics may lead to excessive fluid loss and dehydration. Your healthcare provider may need to adjust your diuretic dose.
- When taken with other medications that lower blood pressure (such as ACE inhibitors, angiotensin receptor blockers), there may be an additive effect, causing further blood pressure reduction.
- It can affect kidney function, so combining it with other medicines may increase the risk of kidney problems.
- Medications that affect blood volume, such as nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, can interact with Jardiance and affect kidney function.
[Note: This isn’t a complete list, and there could be other drugs that interact with Jardiance. Tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]
What Are the Jardiance Alternatives?
If you’re considering alternatives to Jardiance, here are some options within the same class, as well as other types of medications that might be used depending on individual health needs and doctor’s recommendations:
- Glucophage (metformin)
- Januvia (sitagliptin)
- Victoza (liraglutide)
- Starlix (nateglinide)
- Actos (pioglitazone)
- Glyset (miglitol)
- Precose (acarbose)
- Trulicity (dulaglutide)
- Ozempic (semaglutide)
[Note: Your doctor will choose what’s best for you. Only use these alternative medications after consulting your healthcare provider. Taking them by yourself may cause serious side effects.]
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Frequently Asked Questions
Does Jardiance help with heart failure?
Yes, Jardiance is used to treat heart failure. It helps reduce the risk of cardiovascular death and hospitalization for heart failure in adults with heart failure. This medicine helps improve the heart’s ability to pump blood, improving and preventing complications. In addition to reducing the risk of cardiovascular death and hospitalization, Jardiance can also help manage heart failure symptoms and reduce the risk of heart failure-related events. Moreover, it is not recommended for anyone 18 years or younger to use it.
What drugs interact with Jardiance?
Here are the drugs that may interact with Jardiance:
- Diuretics
- Other diabetes drugs [linagliptin (Tradjenta), canagliflozin (Invokana), semaglutide (Ozempic)]
- Certain antibiotics
- Insulin
- Monoamine oxidase inhibitors (MAOIs)
- Lithium (Lithobid)
- Hydroxychloroquine (Plaquenil)
- Fluoxetine (Prozac)
Always consult with your doctor before taking any of these medications.
How to store this medication?
To store this medication, it is important to keep it at room temperature. The ideal storage temperature range for Jardiance is between 68F to 77F (20C to 25C). Please make sure to store it away from the reach of children. Additionally, it is important to note that heat, air, light, and moisture can damage your medicine. Therefore, storing the medicine in a cool, dry place is recommended. Suitable storage locations include a kitchen cabinet or dresser drawer away from the sink, stove, and hot appliances. Also, you can use a shelf, a storage box, or in a closet. By following these instructions, you can ensure that your medication remains safe and effective when needed.
Can Jardiance cause weight loss?
Jardiance might lead to a slight weight loss according to reports from people who participated in clinical trials. However, it’s not entirely certain if this weight loss is directly caused by Jardiance or other factors like changes in diet and exercise. If you’re worried about losing weight while taking Jardiance, it’s best to discuss it with your doctor. They can offer advice on managing your weight and may suggest alternative medications if needed. It’s important to have open communication with your healthcare provider to ensure the best treatment plan for your condition. Additionally, you can consider Jardiance 10 mg buy online from Canada with Polar Bear Meds.
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