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Prograf

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Product Details

Description

Buy Prograf Online from Licensed Canadian Pharmacies

Prograf contains tacrolimus, an immunosuppressant used to prevent organ rejection after kidney, liver, or heart transplants. It works by blocking the immune cells that attack the transplanted organ, helping your body accept the new organ. Available in 0.5 mg, 1 mg, and 5 mg capsules, Prograf is taken orally, usually twice a day, as prescribed by your doctor. Dosage is carefully adjusted based on your transplant type and blood levels.

Common side effects include tremors, headache, nausea, and high blood pressure. Avoid grapefruit products and monitor kidney and liver health regularly. If you miss a dose, take it as soon as possible, but do not take a double dose. Always follow your healthcare provider’s instructions for safe use. You can order Prograf online safely from licensed pharmacies with a valid prescription.

Generic NameTacrolimus
Brand NamePrograf
FormsCapsules
Strengths Available0.5 mg & 1 mg & 5 mg
PackagingNA
Requires PrescriptionPrescription only (Rx)
Ships to the USAYes
Uses and Benefits

Prograf (tacrolimus) is commonly prescribed to prevent:

  • Organ rejection in people who have had a kidney, liver, or heart transplant recently.

Benefits of Prograf

  • Helps lower the risk of organ rejection following kidney, liver, or heart transplantation.
  • Works by dampening the immune response, shielding the transplanted organs from attack.
  • Promotes prolonged survival of the transplanted graft within the recipient.
  • Has the potential to lessen reliance on high doses of corticosteroids after the transplant.
  • Can be safely combined with other immunosuppressive agents to enhance overall effectiveness.
Dosage

Dosage of Prograf for Organ Transplant

Initial Dose:

  • Kidney transplant: 0.2 mg/kg/day orally in two divided doses, started within 24 hours post-transplant.
  • Liver transplant: 0.15 mg/kg/day orally in two divided doses, started 6–12 hours post-surgery.
  • Heart transplant: 0.075 mg/kg/day orally in two divided doses, starting the dose within 24 hours of post-transplant.

Adjustment:

  • Under medical supervision, dosage is adjusted based on patient response, renal and hepatic function, and drug interactions.

Maximum Dose:

  • No maximum fixed dose; dosing is adjusted to produce therapeutic levels in the blood with no toxicity.
Usage Guide

If you choose to buy Prograf online, please follow these administration guidelines to ensure safe and effective use:

  • Store Prograf at room temperature (20°C to 25°C).
  • Swallow capsules whole with water, preferably on an empty stomach.
  • Take Prograf capsules as prescribed by your doctor.
  • Maintain consistent timing for each dose, ideally 12 hours apart.
  • Do not stop or change the dosage of Prograf without consulting your doctor.
How It Works

Prograf (tacrolimus) helps prevent the immune system from rejecting transplanted organs by reducing its activity. It inhibits a specific protein called calcineurin, which plays a key role in activating T-cells—immune cells responsible for triggering rejection. By blocking calcineurin, Prograf reduces the activity of T-cells, helping the body accept the new organ and lowering the risk of transplant rejection. This targeted immunosuppressive action makes Prograf effective in maintaining organ transplant health.

Side Effects

Common Prograf side effects may include:

  • Tremors
  • Headache
  • Increased blood sugar levels
  • Nausea
  • Diarrhea

Serious side effects (rare) of Prograf capsules are:

  • Severe infections due to immune suppression
  • Kidney damage or failure
  • Signs of allergic reaction (rash, swelling, difficulty breathing)
  • Seizures
  • Liver problems

Note: Contact your healthcare provider or pharmacist if you experience any serious symptoms or unusual changes.

Warnings

Consider the following serious warnings when you order Prograf from Canada:

  • Kidney Toxicity: Prograf can impair kidney function, potentially leading to kidney damage. Routine tests to monitor kidney function are advised while undergoing treatment.
  • Risk of Malignancies: Using Prograf for an extended period may raise the risk of certain cancers, such as lymphoma or skin cancer. It’s important to attend regular health checkups and take extra care in the sun.
  • Neurotoxicity: Some patients may experience neurological effects such as tremors, headaches, or seizures. Any unusual neurological symptoms should be reported promptly.
  • Liver Toxicity: Prograf may impact liver function, making regular monitoring of liver enzymes important during treatment. Early detection helps prevent serious complications.
Safety Guide

You should be aware of the following precautionary guidelines if you plan to order Prograf online:

  • Take Only as Directed: Prograf (tacrolimus) must be taken exactly as prescribed to maintain proper immunosuppression. Taking too much can lead to serious infections or toxicity, while taking too little may result in organ rejection.
  • Monitor Kidney and Liver Function Regularly: Prograf can be hard on the kidneys and liver. Routine blood tests are necessary to track organ function and drug levels to prevent long-term damage or complications.
  • Limit Exposure to Sunlight or UV Rays: This medication increases your risk of sunburn and skin cancer. Use sunscreen (SPF 30 or higher), wear protective clothing, and avoid tanning beds.
  • Avoid Live Vaccines: Because Prograf suppresses your immune system, live vaccines (like MMR or yellow fever) may not work properly and could even cause infection. Always consult your doctor before receiving any vaccines.
Missed Dose

If you miss a dose of Prograf, take it as soon as you remember on the same day. If it is time for your next dosage, then skip the missed dose and do not take a double dose. Contact your healthcare provider if you're unsure how to proceed.

Overdose

Accidental overdose of Prograf can lead to serious complications, such as kidney problems, tremors, or high blood pressure. If you suspect an overdose of Prograf, seek medical help or contact a poison control center at 1-800-222-1222. Never adjust your dose without medical supervision.

Storage Guide

If you buy Prograf from Canada, follow these storage instructions:

  • Store Prograf at room temperature, between 20°C to 25°C.
  • Keep Prograf capsules in their original container, tightly closed.
  • Protect Prograf from excessive heat, moisture, and direct sunlight.
  • Do not freeze Prograf or expose it to extreme cold.
  • Dispose of expired or unused medication safely, following local regulations.
Interactions

The following drugs are known to potentially interact with Prograf:

  • Nizoral (Ketoconazole)
  • Erythrocin (Erythromycin)
  • Rifadin (Rifampin)
  • Dilantin (Phenytoin)
  • Prednisone (Corticosteroids)
  • Advil, Motrin (NSAIDs)
  • Gentamicin (Aminoglycosides)
Alternatives

If Prograf is not suitable for you, consider the following alternatives:

  • Neoral (Cyclosporine)
  • Rapamune (Sirolimus)
  • Imuran (Azathioprine)
  • CellCept (Mycophenolate mofetil)
  • Sandimmune (Cyclosporine)
  • Zortress (Everolimus)
Cost & Coupons

Why Buy Prograf from Polar Bear Meds?

At Polar Bear Meds, we’re committed to making prescription medications like Prograf more accessible and affordable for USA patients. Our prices are significantly lower than typical USA pharmacy retail rates without compromising on safety or quality. Every order is sourced exclusively from licensed and trusted pharmacies and undergoes complete prescription verification to ensure compliance and authenticity. We offer discreet, trackable shipping to all USA states, along with refill support for ongoing treatment. Our friendly customer service team is here to help you.

Cost & Coupons

Get Prograf delivered straight from Canada to your doorstep in the USA. You can also save more by using the coupon code “WELCOMEPB10” for 10% off on your first order. There are no hidden handling or processing fees, as we believe in complete transparency. Looking to save even more? Join our referral program & earn a $20 credit every time you refer a friend or a family member. Your referral will also receive a $20 credit, so everyone wins. Additionally, after every 10 verified customers you refer to, you'll receive a $100 credit in your account as a thank-you for spreading the word.

FAQ

Guarantee

AtPolar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently purchase Prograf from Canada at a substantial discount, call us toll-free at1-888-779-2193.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

Find Dr. Jackson Miller on:LinkedIn
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