Propylthiouracil

Buy Propylthiouracil Online from Licensed Canadian Pharmacies

Propylthiouracil (PTU) is an antithyroid medication. It is used to treat hyperthyroidism, including Graves’ disease. It is available in 50 and 100 mg oral tablets. Propylthiouracil helps control excessive thyroid hormone production. It is often prescribed when other treatments, such as radioactive iodine or surgery, are not suitable. Propylthiouracil is also used during the first trimester of pregnancy when methimazole is not recommended. You can order Propylthiouracil medication online from certified Canadian pharmacies that ship directly to the US, provided you have a valid prescription.

Propylthiouracil is used to:

• Treat hyperthyroidism (overactive thyroid gland).
• Manage Graves' disease, especially in cases where radioactive iodine or surgery is not suitable.

Benefits of Propylthiouracil

• Effectively treats hyperthyroidism by reducing the production of thyroid hormones.
• Helps manage symptoms of an overactive thyroid, including rapid heartbeat, weight loss, and nervousness.
• Can be used to prepare patients for thyroid surgery or radioactive iodine treatment.
• Preferred choice for treating hyperthyroidism during pregnancy, especially in the first trimester.
• May help control thyrotoxic crisis (thyroid storm), a life-threatening condition.
• Generally well-tolerated when used under proper medical supervision.
• Can help restore normal thyroid hormone levels within weeks to months of treatment.
• May improve quality of life by alleviating uncomfortable hyperthyroid symptoms.
• Available in oral tablet form for convenient administration.
• Can be used as an alternative to methimazole in patients who cannot tolerate that medication.
• May help prevent complications associated with untreated hyperthyroidism, such as heart problems and bone loss.

Dosage of Propylthiouracil for Hyperthyroidism Treatment

• Initial Adult Dose: Typically 300 to 450 mg daily in divided doses every 8 hours.
• Maintenance Dose: 100 to 150 mg daily in divided doses after thyroid hormone levels normalize.
• Pediatric Dose: Weight-based dosing under physician guidance.
• Pregnancy: Usually 100 to 150 mg/day in divided doses during the first trimester only.

Dosage of Propylthiouracil for Graves' Disease Management

• Initial Adult Dose: 100 mg orally every 8 hours (total daily dose: 300 mg), or up to 450 mg/day in divided doses for severe cases.
• Maintenance Dose: Once thyroid hormone levels are controlled, the dose is usually reduced to 50 to 150 mg per day in divided doses.
• Pediatric Dose: Not routinely recommended for children but may be prescribed in special cases by a specialist, typically at 5 to 7 mg/kg/day in divided doses.
• Pregnancy (First Trimester of Graves' Disease): 100 to 150 mg/day in divided doses, with the lowest effective dose used to maintain thyroid hormone levels in a safe range.

Note: Dosing must always be individualized and adjusted based on thyroid function tests (T3, T4, TSH) and patient response. Regular blood monitoring is essential to ensure efficacy and avoid side effects.

Here’s how to take this medication correctly:

• Take Propylthiouracil tablets exactly as directed by your healthcare provider.
• Tablets can be taken with or without food; taking it with food may help prevent stomach upset.
• Try to take it at the same time(s) each day for best results.
• Do not stop taking this medication suddenly, as it can worsen your condition.
• Routine blood tests are often required to monitor thyroid hormone levels and liver function.

Propylthiouracil works by inhibiting the enzyme thyroid peroxidase, which blocks the synthesis of thyroid hormones (T3 and T4). It also inhibits the conversion of T4 to T3 in peripheral tissues, making it effective for reducing active thyroid hormone levels in the body. These dual actions make it particularly useful in treating thyroid storm and severe hyperthyroidism.

Common Propylthiouracil side effects may include:

• Rash or itching
• Nausea or vomiting
• Upset stomach
• Headache
• Joint or muscle pain
• Loss of taste

Serious side effects (rare):

• Severe liver damage or liver failure
• Agranulocytosis (a dangerous drop in white blood cells)
• Unusual bleeding or bruising
• Fever, sore throat, or signs of infection
• Yellowing of the skin or eyes (jaundice)

Note: Contact your healthcare provider immediately if you experience signs of liver problems, infection, or allergic reactions.

• Propylthiouracil carries a black box warning for serious liver injury, including liver failure, which may be fatal.
• Not recommended for use in children unless absolutely necessary.
• Regular monitoring of liver function and blood counts is essential.
• Avoid use during the second and third trimesters of pregnancy unless no alternatives exist.
• Tell your doctor if you have liver disease, blood disorders, or autoimmune conditions.

• Inform your doctor of all current medications and medical conditions.
• Tell your healthcare provider before any surgeries or new prescriptions.
• Avoid alcohol, which can increase the risk of liver damage.
• Wash hands often and avoid contact with sick individuals while taking PTU due to risk of lowered immunity.
• Use effective birth control while taking PTU if applicable.

• If you miss a dose, take it as soon as you remember.
• If it’s almost time for your next dose, skip the missed dose.
• Do not double up to make up for a missed dose.

Symptoms of overdose may include:

• Nausea
• Vomiting
• Headache
• Drowsiness
• Signs of low thyroid (fatigue, cold intolerance)

Seek immediate medical attention or contact poison control if overdose is suspected.

• Store at room temperature (20 to 25°C or 68 to 77°F).
• Keep away from moisture, heat, and light.
• Keep in the original container, tightly closed.
• Keep out of reach of children and pets.

Let your doctor know if you are taking:

• Coumadin (warfarin)
• Jantoven (warfarin)
• Digoxin (digoxin)
• Synthroid (levothyroxine)
• Metoprolol Succinate ER (metoprolol)
• Metoprolol Tartrate (metoprolol)
• Theophylline (theophylline)
• Dilantin (phenytoin)
• Tegretol (carbamazepine)
• Rifadin (rifampin)
• Tagamet HB (cimetidine)
• Celexa (citalopram)
• Methotrexate (methotrexate)
• Plavix (clopidogrel)
• Eliquis (apixaban)
• Xarelto (rivaroxaban)
• Aspirin (aspirin)
• Tylenol (acetaminophen)
• Vitamin D3 (cholecalciferol)
• Vitamin B12 (cyanocobalamin)
• Xanax (alprazolam)
• Claritin (loratadine)
• Flonase (fluticasone nasal)
• Nexium (esomeprazole)
• Protonix (pantoprazole)

Avoid over-the-counter iodine supplements unless directed by your provider.

Other treatments for hyperthyroidism may include:

• Methimazole (methimazole)
• Tapazole (methimazole)
• Thiamazole (methimazole)
• Carbimazole (carbimazole)
• Lugol’s Solution (potassium iodide / iodine)
• SSKI (potassium iodide)
• Radioactive Iodine (iodine-131)
• Thyroidectomy (surgical alternative)
• Beta-Blockers (e.g., propranolol) for symptom control
• Levothyroxine (levothyroxine) post-ablation or surgery
• PTU (propylthiouracil)
• Propacil (propylthiouracil)
• Propylthiouracil Tablets (propylthiouracil)

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Cost & Coupons

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