Singulair

Singulair, containing the active ingredient montelukast, manages asthma and alleviates allergic rhinitis symptoms by blocking substances called leukotrienes. Available in a 10 mg dosage, it is suitable for adults & children aged six and older and should be taken daily as prescribed, preferably in the evening for asthma relief. Common side effects include headache and stomach pain, with severe reactions like mood changes possible. Take the missed dose of Singulair as soon as you remember unless close to the next scheduled dose. Overdosing requires immediate medical attention. Store it at a controlled room temperature, away from excess heat & moisture. Consult a healthcare provider for customized advice and instructions on using Singulair effectively.

Singulair, also known by its active ingredient montelukast, is a medication primarily used to manage asthma and relieve symptoms of allergic rhinitis. Montelukast works by blocking leukotrienes, which cause asthma and allergic rhinitis symptoms. Singulair helps reduce wheezing, difficulty breathing, nasal congestion, and seasonal allergies by inhibiting these leukotrienes.

Available primarily in a 10 mg dosage, Singulair is recommended for daily use as prescribed by a healthcare provider. It is suitable for adults and children as young as six years old. Patients are advised to take the medication in the evening for asthma or at the same time each day for allergic rhinitis. The mechanism of action involves smooth muscle contraction, preventing airway edema, and altered cellular activity associated with inflammatory processes affecting the airway and nasal passages.

Patients may experience side effects such as headache, stomach pain, heartburn, and tiredness. Serious side effects can include mood changes and an increase in certain white blood cells. It’s crucial to take Singulair exactly as prescribed and not to miss doses to maintain its effectiveness. In case of a missed dose, take it as soon as remembered unless it is almost time for your next dose. Avoid taking double or extra doses. In case of a Singulair overdose, seek immediate medical attention. Store it at room temperature, away from moisture, direct sunlight & heat. Always consult a licensed medical professional for personalized advice & guidance regarding the safe and effective use of Singulair.

It is used for the following purposes:

• Asthma management
• Exercise-induced bronchoconstriction
• Allergic rhinitis

What Are the Forms & Strengths of Singulair?

Singulair is available in the following forms and strengths:

Form: Tablets 

Strength: 10 mg 

Form: Chewable tablets 

Strength: 4 mg, 5 mg 

Form: Oral granules 

Strength: 4 mg 

What Are the Recommended Dosage of Singulair?

For Asthma Prophylaxis and Chronic Treatment

• 10 mg once in the evening, orally with or without food.

For Exercise-Induced Bronchospasm Prevention

• 10 mg once orally by mouth, two hours before exercise

For Allergic or Perennial Rhinitis Relief

• 10 mg once daily orally by mouth

[Note: These recommendations may vary from person to person. Discuss them with your doctor, and they’ll customize your dosage accordingly.]

• Before taking this medication, carefully read and follow the instructions for use given in the patient information leaflet that came along with your prescription. Talk to your physician or medical provider if you do not understand any part of the leaflet.
• Take Singulair orally by mouth with or without food. Take it exactly as directed by your doctor at the same time every day.
• If this medication upsets your stomach, you should take it with food. Continue taking your medication precisely as your doctor directs unless instructed otherwise.
• This medication is to be taken once daily in the evening to prevent asthma or symptoms of an allergy.
• For exercise-induced bronchoconstriction, you should take one dose of Singulair at least two hours before you exercise and do not take an extra dose for at least 24 hours.
• Talk to a licensed healthcare professional before using this medication in pediatric patients. While it is safe for use in children under 15 years to treat certain conditions, precautions do apply.
• This medication should not be used during an ongoing asthma or bronchospasm attack. Use only rapid-acting inhalation medication for an attack. Seek immediate medical attention if your breathing problem worsens quickly or if you suspect your medications are not working as well as they should be.
• You should chew the tablet right before swallowing it.
• You can directly place the granules in your mouth and swallow them or mix them with a spoonful of mashed carrots, applesauce, ice cream, or rice. You can also mix them with one tablespoon of breast milk or baby formula. You should not use any other type of liquid to mix the granules.
• After mixing the oral granules, use them within fifteen minutes. Do not save an open packet or mixed or diluted medication for later use.
• It may take up to several weeks before you start noticing improvements in your symptoms.
• Continue taking the medicine for the duration specified by your doctor. Tell them if your condition does not improve or if it worsens.
• You should use this medication as your doctor prescribes. Your doctor may need to change your dosage due to surgery, stress, illness, or a recent asthma attack. Do not change your dose or dosage schedule without your doctor’s advice. Tell your doctor if any of the medications don’t seem to work.
• If you also use an oral steroid, you should not stop using this medication abruptly. If you plan to discontinue taking this medication, you should consult a licensed healthcare provider, they will help you gradually taper off the prescription.
• Store the medicine in a tightly closed container, away from sunlight, moisture, and heat.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

Singulair, also known as montelukast, works by blocking leukotriene receptors in the airways. Leukotrienes are substances released during inflammation and exposure to allergens, which can cause symptoms like airway edema, smooth muscle contraction, and increased mucus production. Singulair helps reduce inflammation, relax the smooth muscles, and alleviate symptoms of asthma and allergic rhinitis by inhibiting these receptors. This effectively prevents asthma attacks and relieves allergy symptoms such as sneezing, runny nose, and nasal congestion.

Common Side Effects of Singulair: Similar to other medications, Singulair may also cause certain side effects in some people. It is important to mention that not everyone using this medication will experience these side effects. The side effects usually don’t require medical attention and disappear within a few days as your body adjusts to the medication. If you are concerned about the side effects caused by this medication, you can consult your doctor, who will help you prevent and manage the side effects. Side effects caused by Singulair are as follows:

• Headache
• Upper respiratory infection
• Fever
• Cough
• Abdominal pain
• Diarrhea
• Fatigue
• Sore throat
• Nasal congestion
• Flu-like symptoms

Mild Side Effects of Singulair: Singulair may cause mild side effects in some people, which are not usually severe and disappear within a few days or weeks. Inform your doctor if your symptoms continue or if they become bothersome. This list does not include all possible side effects, and there may be others. Report any new or worsening symptoms to your doctor. 

• Nausea
• Vomiting
• Dizziness
• Skin rash
• Mild allergic reactions
• Tooth pain
• Ear pain or infection
• Muscle or joint pain
• Indigestion
• Insomnia

Serious Side Effects of Singulair: Your doctor has prescribed Singulair because they have determined that the benefits of this medication outweigh the risks associated with its use. Rarely, Singulair may cause severe side effects in some people. These side effects require prompt medical assistance and may become life-threatening if not treated promptly. If you experience any of the following symptoms, discontinue using this medication and immediately call your doctor. 

• Neuropsychiatric events (agitation, aggression, anxiety, depression, suicidal thoughts)
• Eosinophilic conditions, including Churg-Strauss syndrome. Symptoms may include worsening pulmonary symptoms, cardiac complications, and neuropathy.
• Severe allergic reactions, including anaphylaxis, may occur. Its symptoms may include swelling of the face or throat, difficulty breathing, and rapid heartbeat.
• Liver problems (hepatitis, increased liver enzymes)
• Increased chance of bleeding, particularly in patients with clotting disorders
• Severe skin reactions (Stevens-Johnson syndrome, erythema multiforme)
• Hallucinations, more common in pediatric patients
• Seizures
• Pancreatitis. Its symptoms may include extreme abdominal pain, nausea, vomiting.
• Systemic vasculitis

[Note: This list may not cover all possible side effects. Always consult with your healthcare provider for medical advice about side effects.]

• You should not use Singulair to treat sudden asthma attacks. Asthma patients should always have a rescue inhaler with them.
• People allergic to Singulair, montelukast, or of its excipients should not use this medication.
• Singulair is indicated for use in adults and children at least 12 months old for treating asthma and patients at least six years old for treatment prevention of exercise-induced asthma. It can be used for seasonal allergies in patients aged two years and more. It is approved for children six months of age and older to treat year-round allergies.
• You should not use Singulair if you are pregnant. You should consult your doctor to determine other treatment options while pregnant.
• It is not known if this drug passes into your breast milk. Talk to your healthcare provider before breastfeeding an infant while using this medication.

What Are the FDA Boxed Warning for Singulair?

A boxed warning for Singulair has been issued by the FDA due to severe mental health risks associated with its use. The key points of the boxed warning include:

• These events include suicidal thoughts and actions, as well as other mental health issues such as agitation, depression, sleep problems, aggressive behavior, and attention problems.
• Medical providers are advised to carefully evaluate the risks and benefits of montelukast for each patient before prescribing or continuing treatment.
• Patients taking Singulair should be closely monitored for neuropsychiatric symptoms, including changes in behavior or mood.
• Healthcare providers must inform patients and caregivers about these risks, instruct them to discontinue the medication, and seek medical help immediately if any new neuropsychiatric symptoms occur.
• The FDA recommends considering alternative treatments for patients with allergic rhinitis if symptoms are mild, reserving montelukast for those who haven’t responded adequately to other therapies.
• In the case of asthma treatment, healthcare providers should carefully weigh the benefits of the drug against its potential risks before prescribing Singulair.

• Before taking Singulair, tell your doctor if you have an allergy to montelukast or any other medications. Also, tell them if you have ever had an allergic reaction to any of the ingredients present in the product. You can ask your doctor, pharmacist, or healthcare provider for the full list of ingredients.
• Before taking this medication, tell your doctor about all the medications you are currently taking or plan to take, including prescription, non-prescription, over-the-counter, herbal, or vitamin supplements. This information will help them determine if this medication is right for you.
• Before taking this medication, share your medical and family history with your doctor, especially if there is a history of mental health problems or aspirin allergy.
• The chewable form of Singulair tablet contains aspartame, which may be harmful if you have phenylketonuria.

Singulair is contraindicated for use in patients who:

• Have hypersensitivity to Singulair, montelukast, or any of its components.
• Have acute asthma attacks
• Known aspirin sensitivity (caution required during use)
• Have phenylketonuria
• Hepatic impairment
• Have a history of depression or suicidal thoughts. (caution is advised)
• Are younger than 12 months

• If you have missed a dose of Singulair, you should take it as soon as you remember.
• However, if it is almost time to take your next dose, you may omit the missed dose and continue taking your medication according to your regular dosing schedule.
• Do not simultaneously take double or extra doses of the same medication to compensate for the missed dose.
• You can set a reminder on your phone to prevent missing doses further. Medication reminders work best for this purpose.

[Note: If you have missed a medication dose and are unsure when to take the next one, consult your doctor or pharmacist immediately.]

If someone has taken Singulair more than recommended, you should seek immediate medical attention. Singulair overdose symptoms may include thirst, sleepiness, dilated pupils, and abdominal pain. You can call your doctor, 911, or poison control helpline. You can also head to the nearest emergency room.

[Note: If you consumed more than the recommended dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

• You should keep Singulair in its original container tightly closed at room temperature between 20-25°C or 68-77°F, away from moisture, direct sunlight, and moisture.
• Do not keep it in the bathroom or near the sink.
• Keep all medications, including Singulair, in a safe place, away from the sight and reach of children and pets.
• Don’t keep medications that are outdated or no longer needed. Discard them safely.
• You should not dispose of unwanted medications by pouring them into the drain, flushing them down the toilet, or throwing them into the household garbage bin.
• You should eliminate unwanted medications in such a way that prevents children, animals, and others from consuming them.
• To learn more about how to dispose of unwanted medications, consult your pharmacist, healthcare provider, or local waste disposal company.

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

Certain medications may interact with Singulair and affect how it works. Before using this medication, inform your medical provider about all the medicines you are taking currently or plan to take, including all prescription, non-prescription, and over-the-counter drugs, herbal, or vitamin supplements. This information will help them identify and prevent potential drug interactions. If you are concerned about Singulair interactions, you should consult your doctor. This list is not complete, and there may be other drug interactions with Singulair.

• Phenobarbital
• Rifampin
• Carbamazepine (Tegretol)
• Phenytoin (Dilantin)
• Gemfibrozil (Lopid)
• Theophylline
• Warfarin
• Corticosteroids
• Other asthma medications

What Are the Other Singulair Interactions?

Apart from the drug interactions, Singulair may also have certain interactions with herbs, supplements, food items, and beverages. This list may not be exhaustive, and you should always consult your healthcare provider or doctor for personalized advice. Significant interactions of Singulair with herbs may include:

• St. John’s Wort

[Note: This isn’t a complete list, and there could be other drugs that interact with Singulair. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

People look for alternative medications to Singulair when it does not suit them or do not produce the desired results. Many effective alternative medicines to Singulair are available in the market. However, you should consult a licensed healthcare provider before taking a new medication. They will help you determine which medication works best for you. Some of the popular alternative medicines are given below.

• Fluticasone nasal (Fluticasone Propionate)
• Loratadine
• Montelukast
• Allegra
• Claritin
• Fexofenadine

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]

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