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Tacrolimus

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Product Details

Description

Buy Tacrolimus Online from Licensed Canadian Pharmacies

Tacrolimus is an immunosuppressive agent designed to help prevent the body from rejecting transplanted kidneys, livers, or hearts. It functions by reducing the immune system’s response. Available in strengths of 0.5 mg, 1 mg, and 5 mg, Tacrolimus is taken orally, usually twice daily, under medical supervision.

Headaches, tremors, and high blood pressure are a few common side effects. If you miss a dose, take it as soon as possible. Store the capsules at room temperature, away from moisture. You can conveniently order Tacrolimus online from licensed Canadian pharmacies for safe and reliable delivery.

Generic NameTacrolimus
Brand NamePrograf
FormsCapsules
Strengths Available0.5 mg & 1 mg & 5 mg
PackagingNA
Requires PrescriptionPrescription only (Rx)
Ships to the USAYes

Uses and Benefits

Tacrolimus is prescribed to treat:

  • Prevention of organ rejection after kidney, liver, and heart transplant

Benefits of Tacrolimus

  • Effectively reduces the risk of organ rejection by suppressing the immune system after a transplant.
  • Specifically targets immune cells responsible for attacking transplanted organs, helping improve graft survival rates.
  • May decrease the need for high doses of corticosteroids, reducing steroid-related side effects.
  • Can be combined with other immunosuppressive medications to enhance overall treatment effectiveness.
  • Supports the long-term health and function of transplanted kidneys, livers, and hearts.
Dosage

Dosage of Tacrolimus for Organ Transplant

Initial Dose:

  • Kidney transplant: 0.2 mg/kg/day orally in two divided doses, started within 24 hours post-transplant.
  • Liver transplant: 0.15 mg/kg/day orally in two divided doses, started 6–12 hours post-surgery.
  • Heart transplant: 0.075 mg/kg/day orally in two divided doses, starting the dose within 24 hours of post-transplant.

Adjustment:

  • Under medical supervision, dosage is adjusted based on patient response, renal and hepatic function, and drug interactions.

Maximum Dose:

  • No maximum fixed dose; dosing is adjusted to produce therapeutic levels in the blood with no toxicity.
Usage Guide

The essential tips to follow when you buy Tacrolimus online for safe and effective use.

  • Take Tacrolimus capsules exactly as prescribed by your healthcare provider.
  • Swallow capsules whole with water, preferably on an empty stomach.
  • Maintain consistent timing for each dose, ideally 12 hours apart.
  • Avoid grapefruit and grapefruit juice to prevent drug interactions.
  • Do not alter or stop the dose without consulting your doctor.
How It Works

Tacrolimus works by inhibiting a key protein called calcineurin, which is essential for activating T-cells in the immune system. By blocking this protein, the drug prevents T-cells from triggering an immune response against transplanted organs. This targeted suppression helps the body accept the new organ and reduces the risk of rejection, making Tacrolimus an effective immunosuppressant in transplant patients.

Side Effects

Common Tacrolimus side effects may include:

  • Tremors
  • Headaches
  • Nausea
  • Increased blood sugar levels
  • Diarrhea
  • High blood pressure
  • Changes in kidney function

Serious side effects (rare) of Tacrolimus capsules are:

  • Severe infections due to immune suppression
  • Kidney damage or failure
  • Allergic reactions (rash, swelling, difficulty breathing)
  • Seizures
  • Liver complications
  • Increased risk of certain cancers

Note: Contact your healthcare provider or pharmacist if you experience any serious symptoms or unusual changes.

Warnings

Consider the following severe warnings when you order Tacrolimus from Canada:

  • Kidney Damage: Tacrolimus can impair kidney function, potentially leading to kidney injury or failure. Regular blood tests are crucial to monitor kidney health and adjust dosage as needed to prevent long-term damage.
  • High Blood Pressure: Use of Tacrolimus may cause or worsen hypertension, increasing the risk of heart disease or stroke. Blood pressure should be regularly checked and managed with lifestyle changes or medication.
  • Neurological Side Effects: Some individuals may develop neurological symptoms such as tremors, headaches, confusion, or seizures. These symptoms require immediate medical evaluation to avoid complications.
  • Liver Toxicity: Tacrolimus may negatively affect liver function, so liver enzyme levels should be monitored frequently. Early detection helps prevent serious liver damage or failure.
Safety Guide

You should be aware of the following precautionary guidelines if you plan to order Tacrolimus online:

  • Take Exactly as Prescribed: Follow your healthcare provider’s directions closely to maintain the right balance of immune suppression and avoid complications like organ rejection or harmful side effects.
  • Avoid Grapefruit Products: Grapefruit & grapefruit juice can affect how tacrolimus is broken down in your body, potentially causing dangerous increases in drug levels that raise the risk of side effects.
  • Limit Sun Exposure: This medication can make your skin more sensitive to UV rays, increasing the chance of sunburn or skin damage.
  • Skip Live Vaccines: Since tacrolimus suppresses your immune system, live vaccines (like MMR or yellow fever) could be ineffective or harmful. Always talk with your healthcare provider before getting vaccinated.
Missed Dose

If you miss a Tacrolimus dose, take it when you remember on the same day. If it’s time for your next dose, skip the missed one—do not take a double dose. Always follow your healthcare provider’s instructions and contact them if you’re unsure how to proceed.

Overdose

Taking too much Tacrolimus can cause serious health problems such as kidney damage, tremors, high blood pressure, or seizures. If you suspect Tacrolimus overdose, seek medical attention immediately or contact the poison control center at 1-800-222-1222. Do not try to adjust your dose without medical guidance.

Storage Guide

If you buy Tacrolimus from Canada, follow these storage instructions:

  • Store Tacrolimus at room temperature, ideally between 20°C and 25°C (68°F to 77°F).
  • Protect from exposure to heat, moisture, and direct sunlight.
  • Keep out of reach of children & pets.
  • Keep Tacrolimus capsules in their original container.
  • Do not freeze the medication or expose it to extreme cold.
  • Dispose of expired medicine according to local regulations.
Interactions

Tacrolimus may interact with several medications, which can affect how it works. It’s important to inform your healthcare provider about all medicines you are taking.

  • Nizoral (Ketoconazole)
  • Erythrocin (Erythromycin)
  • Rifadin (Rifampin)
  • Dilantin (Phenytoin)
  • CellCept (Mycophenolate mofetil)
  • Advil, Motrin (Ibuprofen - NSAIDs)
Alternatives

If Tacrolimus is not suitable or causes unwanted side effects, other immunosuppressant medications may be considered. These include:

Cost & Coupons

Why Buy Tacrolimus from Polar Bear Meds?

At Polar Bear Meds, we’re committed to making prescription medications like Tacrolimus more accessible and affordable for USA patients. Our prices are significantly lower than typical USA pharmacy retail rates without compromising on safety or quality. Every order is sourced exclusively from licensed and trusted pharmacies and undergoes complete prescription verification to ensure compliance and authenticity. We offer discreet, trackable shipping to all USA states, along with refill support for ongoing treatment. Our friendly customer service team is here to help you.

Cost & Coupons

Get Tacrolimus delivered straight from Canada to your doorstep in the USA. You can also save more by using the coupon code “WELCOMEPB10” for 10% off on your first order. There are no hidden handling or processing fees, as we believe in complete transparency. Looking to save even more? Join our referral program & earn a $20 credit every time you refer a friend or a family member. Your referral will also receive a $20 credit, so everyone wins. Additionally, after every 10 verified customers you refer to, you'll receive a $100 credit in your account as a thank-you for spreading the word.

FAQ

Guarantee

AtPolar Bear Meds, your safety is our priority. Every order is dispensed from a fully licensed Canadian pharmacy following strict standards for quality, security, and patient care. To conveniently purchase Tacrolimus from Canada at a substantial discount, call us toll-free at 1-888-779-2193.

Important Notice

The content provided on the Polar Bear Meds website serves to increase knowledge about healthcare products and medical conditions and is strictly for informational purposes. It should not replace professional medical advice. We urge you to consult with a qualified healthcare professional prior to utilizing any prescription or over-the-counter medication. Our platform grants access to an extensive array of products, sourced internationally, including Canada. We collaborates with a licensed pharmacy partner in Canada and trusted dispensing pharmacies globally. All affiliated fulfillment centers are accredited by the regulatory authorities of their respective countries.

Dr. Jackson Miller

Medically Reviewed by "Dr. Jackson Miller (M.D)"

Dr. Jackson Miller is a board-certified medicine physician & hospitalist. He is a healthcare professional with a strong background in patient care. With years of experience and a patient-first approach, he believes the foundation of good health is a patient who feels informed and empowered. He contributes to medical content review, drawing on his background in clinical practice and patient education. He focuses on presenting health information in a clear, accurate, and accessible way to help readers make informed decisions. His work emphasizes clarity, evidence-based guidance, and understandable explanations of medical topics.

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