Olmesartan / Amlodipine / Hydrochlorothiazide 

Tribenzor 

Tribenzor is a multifaceted antihypertensive medication combining olmesartan, amlodipine, and hydrochlorothiazide. This trio targets different aspects of blood pressure regulation: olmesartan prevents blood vessels from tightening, amlodipine relaxes blood vessel walls, and hydrochlorothiazide reduces fluid overload, collectively helping to lower blood pressure and minimize risks of heart attack, stroke, and kidney failure. This blood pressure medication Tribenzor is available in various dosages and must be taken consistently. It is not suitable during pregnancy or for those with severe renal impairments. So, make sure to consult before you buy Tribenzor online from Canada or start using it.

Product Overview

Tribenzor is an advanced medication specifically formulated for managing high blood pressure. It combines three potent active ingredients: olmesartan, amlodipine, and hydrochlorothiazide, each playing a unique role in blood pressure control. Olmesartan acts as an angiotensin II receptor blocker, preventing angiotensin II from causing blood vessel constriction. 

Amlodipine, a calcium channel blocker, helps relax and expand blood vessel walls, improving blood flow. Hydrochlorothiazide, a diuretic or “water pill,” assists in eliminating excess fluid from the body, thus reducing the overall blood volume and pressure. Tribenzor is designed for flexible dosing and is available in multiple strengths to tailor treatment to individual needs based on medical history and response to therapy. 

It is crucial for patients to take this medication consistently at the same time each day to maintain stable blood pressure levels. Regular health checks are necessary to adjust dosages and monitor side effects, particularly in patients with pre-existing health conditions. Pregnant women and individuals with severe renal impairments should avoid using Tribenzor due to potential risks.

What Is Tribenzor Used For?

Tribenzor is used to treat the following medical conditions:

• Olmesartan medoxomil
• Amlodipine
• Hydrochlorothiazide

What Strengths Does Tribenzor Come In?

Tribenzor is available in several combination dosages of its three active ingredients: amlodipine, olmesartan, and hydrochlorothiazide. Here are the forms and strengths in which Tribenzor is typically available:

• 20 mg/5 mg/12.5 mg
• 40 mg/5 mg/12.5 mg
• 40 mg/5 mg/25 mg
• 40 mg/10 mg/12.5 mg
• 40 mg/10 mg/25 mg

What Is the Typical Dosage of Tribenzor?

The recommended dosage of Tribenzor, which combines amlodipine, olmesartan, and hydrochlorothiazide, can vary depending on several factors, including the patient’s response to treatment, existing health conditions, and previous treatments. Here’s a general guide on how Tribenzor is typically dosed:

Dosage for Adults

• Starting Dosage: Typically, Tribenzor is prescribed when individual components (amlodipine, olmesartan, and hydrochlorothiazide) have been used first to establish tolerance and need. The starting dose can depend on the dosages of these individual components the patient was previously taking.
• Maintenance Dosage: Adjustments may be made based on the blood pressure response, usually not more frequently than once every 2-4 weeks. The doctor might increase the dose if the desired blood pressure goal isn’t achieved.

Dosage for Elderly Patients

• Elderly patients may start on a lower dose due to potentially increased sensitivity to the medication and a higher likelihood of kidney or liver function impairment. The healthcare provider will closely monitor the response and adjust the dosage accordingly.

Dosage for Patients with Renal or Liver Impairment

• Mild to Moderate Renal Impairment: Practice caution, and starting with a lower dose may be considered as hydrochlorothiazide and olmesartan are excreted via the kidney.
• Severe Renal Impairment or Dialysis: Tribenzor is generally not recommended due to hydrochlorothiazide, which requires renal excretion and may not be effectively cleared in these patients.
• Liver Impairment: Individuals with mild to moderate liver issues should also start with a lower dosage due to the slower metabolism of the drug components, particularly amlodipine.

Special Considerations

• Avoid in Pregnancy: Tribenzor is contraindicated during pregnancy due to the danger of harm to the unborn baby associated with the use of olmesartan.
• Monitor Electrolytes: Patients should monitor their electrolytes, as imbalances can occur, especially with hydrochlorothiazide.

• Maximum Dosage: Your doctor will determine the safest dose of this medication for you based on your specific needs. It’s important to follow their guidance to ensure the best results from your treatment.

[Note: These recommendations may vary from person to person. Discuss them with your doctor, and they’ll customize your dosage accordingly.]

How Do You Use Tribenzor? 

Always take Tribenzor precisely as your healthcare provider prescribes it. Do not change the dose or frequency without first consulting your doctor. Here are some guidelines you may follow to take your tribenzor medication properly:

• Tribenzor is typically taken once a day. Try to take it simultaneously each day to maintain an even level of medication in your blood.
• Tribenzor can be taken with or without food. If you experience stomach upset with the medication, try taking it with food.
• Do not crush, chew, or break the Tribenzor tablet. Swallow it whole with a glass of water.
• Since Tribenzor contains a diuretic component, it is important to stay adequately hydrated. Discuss with your healthcare provider how much fluid you should consume daily.
• Routine check-ups with your healthcare specialist are essential to monitor your blood pressure and adjust the medication as needed. Keep track of your blood pressure readings and share them with your doctor during your visits.
• If you miss a dose, take it as soon as you remember. However, if it’s close to the time of your next dose, skip the missed dose & resume your regular schedule. Do not take two doses at once.
• Especially in the beginning stages of treatment or when the dose is adjusted, stand up slowly from a sitting or lying position. This medication can cause dizziness during sudden changes in posture.
• Do not stop taking Tribenzor without first discussing it with your healthcare expert. Sudden discontinuation of the medicine can lead to a rebound increase in blood pressure.

[Note: Your doctor will decide the correct dosage amount for you based on your health condition, following guidelines & studies on the drug. They’ll further adjust it as needed over time.]

How Does Tribenzor Work?

Blood pressure medication Tribenzor, effectively manages high blood pressure by combining three different medications that each target blood pressure control through unique mechanisms. Olmesartan, an angiotensin II receptor blocker (ARB), helps by blocking the action of angiotensin II, a chemical that tightens blood vessels. This action allows the blood vessels to relax and widen, lowering blood pressure. Amlodipine, a calcium channel blocker, prevents calcium from entering the heart and blood vessel cells, which helps relax these areas and reduce blood pressure as well as chest pain. Lastly, Hydrochlorothiazide, a diuretic commonly referred to as a “water pill,” works by removing excess salt and water from the body through urine, reducing the volume of blood, which eases pressure on blood vessel walls. Together, these three drugs provide a comprehensive approach to blood pressure management.

What Are the Important Safety Information for Using Tribenzor?

What Are the Side Effects of Tribenzor?

Common Tribenzor Side Effects: Like all medications, Tribenzor blood pressure medicine can cause side effects, which are usually temporary, lasting a few days to weeks. If these side effects persist beyond this time, become bothersome, or intense, it’s important to contact your doctor or pharmacist to discuss your symptoms and ensure your treatment is safe. Here are some common side effects you might experience while taking Tribenzor:

• Dizziness: You may feel lightheaded or as if you might faint, especially when standing up quickly.
• Headache: Experiencing pain or discomfort in your head.
• Fatigue: Feeling unusually tired or lacking energy.
• Swelling of the ankles, feet, or hands (edema): This is when parts of your body swell due to fluid buildup.
• Nausea: Feeling sick in your stomach, which may lead to vomiting.
• Muscle spasms: Unexpected and often painful muscle contractions.
• Back pain: Discomfort or pain located anywhere on your back.
• Joint pain: Discomfort or pain in any joint.
• Upper respiratory tract infection: Symptoms might include a cough, sore throat, or stuffy nose.
• Urinary tract infection: Symptoms can include a burning sensation when urinating, an increased need to urinate, or cloudy urine.
• Increased urination: Needing to urinate more frequently than usual.
• Flu-like symptoms: Feeling generally unwell, which may include fever, chills, and body aches.
• Rash: Noticeable changes on the skin, such as red patches or bumps.
• Dry mouth: Less saliva than usual, making your mouth feel dry.
• Diarrhea or constipation: Changes in bowel movements, either more frequent or less frequent.
• Abdominal pain: Pain or discomfort in your stomach area.

Serious Tribenzor Side Effects: While Tribenzor is effective for managing high blood pressure, it can sometimes cause serious side effects that require immediate medical attention. If you experience any of the following serious side effects, contact your doctor right away. In cases where the side effects seem life-threatening, or if you think you’re having a medical emergency, call your local emergency number or 911 immediately. Here are some serious side effects associated with Tribenzor:

• Severe Hypotension (Low Blood Pressure): This can make you feel extremely dizzy, faint, or lightheaded, especially when you stand up quickly from sitting or lying down.
• Worsening Chest Pain or Heart Attack: If you notice new or increasing chest pain, it could be a sign of a heart attack or angina, especially if you already have heart disease.
• Kidney Problems: If you experience a decrease in how often you urinate, swelling in your feet or ankles, or if you feel unusually tired or have difficulty breathing, these could be signs that your kidney function is worsening.
• Electrolyte Imbalances: Watch out for severe dry mouth, intense thirst, feeling very weak or lethargic, being unusually drowsy or restless, feeling confused, having seizures, muscle pain or cramps, feeling exhausted, having low blood pressure, producing less urine than normal, or experiencing nausea and vomiting. These symptoms indicate a serious imbalance in the body’s salt and mineral levels.
• Vision Changes: Sudden problems with your sight, such as blurry vision or seeing halos around lights, could be signs of severe eye conditions like acute myopia or angle-closure glaucoma, which need urgent medical treatment.
• Allergic Reactions: Severe allergies can manifest as swelling of the face, lips, tongue, or throat, difficulty breathing, or developing hives. These reactions require immediate medical attention.
• Lupus-like Syndrome: If you notice new or worsening joint pain, a rash especially on your cheeks or arms that worsens in sunlight, unusual fatigue, or fever, these could be signs of a lupus-like syndrome induced by the medication.

[Note: Remember, this list does not cover all possible side effects of Tribenzor. Always consult your healthcare expert for medical advice regarding the medication side effects.]

Are There Any Warnings for Using Tribenzor? 

Tribenzor blood pressure medicine poses several serious health risks, particularly for specific groups. Consult your doctor or pharmacist if you have concerns or are considering alternative treatments.

• Risk Warning: Not for Use During Pregnancy Tribenzor is contraindicated during pregnancy as it may cause severe, potentially fatal harm to the unborn baby. If you are pregnant or plan to become pregnant, discuss alternative blood pressure treatments with your healthcare provider. Stop using Tribenzor immediately if you are pregnant, and inform your doctor.
• Low Blood Pressure: Common factors that increase the risk include dehydration, prolonged diarrhea or vomiting, low sodium levels, high doses of diuretics, or aortic stenosis. Initial use or an increase in dose may cause significant drops in blood pressure, manifesting as dizziness or fatigue. Maintain adequate hydration to mitigate this risk. Contact your healthcare expert if you experience severe dizziness or fainting, especially after a fall or head injury.
• Risk of Heart Attack or Chest Pain: Individuals with severe coronary artery disease may experience worsening chest pain or a heart attack when starting Tribenzor or increasing the dosage. Reach out for medical attention right away if you have chest pain, pressure, heartburn, dizziness, or difficulty breathing.
• Worsening Kidney Problems: Blood pressure medication Tribenzor, can impair kidney function, which is an elevated risk in individuals with pre-existing kidney issues or heart failure. Regular lab tests are essential to monitor kidney health. Report any reduction in urine frequency to your provider, as it may indicate deteriorating kidney function.
• Changes in Electrolyte, Blood Sugar, and Cholesterol Levels: Tribenzor may alter levels of electrolytes, blood sugar, and lipids, necessitating frequent blood tests. Inform your provider of all medications you’re taking and report symptoms like rapid heartbeat, muscle pain, weakness, nausea, or vomiting, which could indicate serious electrolyte imbalances.
• Vision Problems: Tribenzor’s hydrochlorothiazide component can cause acute vision changes or eye pain. Immediately report any vision alterations to your provider. Discontinue use & seek urgent medical attention if symptoms persist, as surgical intervention may be necessary to prevent permanent vision loss.
• Lupus: Hydrochlorothiazide in Tribenzor may trigger or exacerbate lupus. Alert your provider if you experience extreme joint pain, fatigue, or a butterfly-shaped rash on the face indicative of lupus symptoms.

Does Tribenzor Have a FDA Boxed Warning?

Tribenzor carries an FDA-boxed warning regarding the risk of harm to an unborn baby when used during pregnancy. The specific warnings include:

• Harm to Unborn Babies: Tribenzor contains olmesartan, a drug known to cause injury or death to a developing fetus when taken during the second & third trimesters of pregnancy. Exposure to olmesartan can lead to fetal toxicity, including hypotension, neonatal skull hypoplasia, anuria, renal failure, and death.

Due to these risks, pregnant women are advised not to take Tribenzor, and women of childbearing age should be informed about the potential hazards to the fetus. If pregnancy is detected during treatment, Tribenzor should be discontinued as soon as possible. Alternative antihypertensive treatments that have safer profiles during pregnancy should be considered.

What Precautions Should Be Taken While Taking Tribenzor?

When taking Tribenzor, it’s essential to consider several precautions to ensure safe and effective medication use. Here are the essential precautions:

• Blood Pressure Monitoring: Routine blood pressure monitoring is crucial to ensure that Tribenzor effectively controls your blood pressure without causing it to drop too low.
• Electrolyte Imbalance: Tribenzor can affect your body’s electrolyte balance, leading to low levels of potassium, magnesium, and sodium. Your healthcare expert may recommend periodic blood tests to monitor your electrolyte levels.
• Kidney Function: Since Tribenzor can affect kidney function, your provider may conduct regular kidney function tests, especially if you have existing kidney issues.
• Pregnancy and Breastfeeding: Tribenzor is not prescribed during pregnancy due to the chances of harm to the unborn baby. Discuss with your healthcare specialist if you are pregnant or planning to become pregnant. It’s also advisable to talk about breastfeeding as it’s unclear if the components of Tribenzor pass into breast milk.
• Allergic Reactions: Inform your healthcare specialist if you have a history of allergic reactions to any component of Tribenzor, especially if you have had allergies to sulfa drugs, as this medication contains hydrochlorothiazide, a sulfa derivative.
• Avoid Alcohol: Alcohol can enhance the blood pressure-lowering effects of Tribenzor and increase the risk of side effects such as dizziness and fainting.
• Surgery or Anesthesia: If you are scheduled for surgery or are to receive anesthesia, inform your surgeon or anesthesiologist that you are taking Tribenzor, as it may affect blood pressure control during and after the procedure.
• Dizziness and Light-headedness: Be cautious when standing up from a sitting or lying position, as Tribenzor can cause dizziness and light-headedness due to blood pressure changes.

What If You Miss a Dose of Tribenzor?

If you miss a dose of Blood pressure medication Tribenzor, take it as soon as you remember. However, if it’s close to your next scheduled dose of Tribenzor, skip the missed dose & continue with your routine dosing schedule. Do not take two doses of this medicine at once to make up for a missed dose, as this can lead to potential overdose symptoms or increased side effects. It’s essential to take Tribenzor consistently to maintain adequate blood pressure control. If you frequently miss doses, consider setting reminders or alarms to help ensure you take your medication as prescribed. Always discuss any concerns about missed doses or how to manage missed doses with your healthcare provider.

[Note: If you have missed a dose of Tribenzor and are unsure when to take the next dose, quickly consult your doctor or pharmacist.]

What Happens If You Take Too Much Tribenzor?

Taking too much Tribenzor blood pressure medicine can lead to serious complications due to an excessive drop in blood pressure and other severe side effects. Symptoms of an overdose might include extreme dizziness, fainting, rapid or unusually slow heartbeat, and possibly confusion or disorientation. In severe cases, an overdose of Tribenzor could result in shock or organ failure due to prolonged low blood pressure. If you suspect that you or someone else has taken an overdose of Tribenzor, it’s crucial to seek emergency medical attention immediately. Provide the healthcare professionals with as much information as possible, such as how much was taken and when. Prompt medical intervention is crucial to manage the symptoms effectively and prevent possible long-term damage.

[Note: If you have consumed more than the recommended dose of Tribenzor, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

How Do You Store Tribenzor?

To ensure that Tribenzor remains effective and safe for use when you buy Tirbenzor online, follow these storage guidelines:

• Store Tribenzor at room temperature, usually between 20°C to 25°C.
• Keep the medication away from excessive moisture and light. Do not store it in the bathroom or near a sink; avoid places exposed to high humidity or direct sunlight.
• Keep Tribenzor in its original packaging until it is time to take the medication. This helps protect it from environmental conditions and ensures it does not get mixed up with other medicines.
• Store Tribenzor out of reach of children and pets to prevent accidental ingestion.
• Regularly check the expiration date on the Tribenzor packaging, and do not use the medication past this date. Dispose of expired or unused medicines properly, following guidelines to ensure they do not harm others or the environment.

[Note: Discuss with your healthcare expert the proper disposal of unused medication and any questions you may have regarding its storage.]

What Drugs Should Not Be Taken with Tribenzor?

Blood pressure medication Tribenzor, is a combination medication used to treat high blood pressure, but it can interact with several other drugs. Here’s a simple explanation of what to watch out for:

• NSAIDs (Nonsteroidal Anti-Inflammatory Drugs): Common pain relievers like ibuprofen and naproxen may make Tribenzor less effective and could also increase the risk of kidney problems.
• Lithium: Taking Tribenzor can raise the levels of lithium in your blood, which might lead to lithium toxicity, a serious condition.
• Aliskiren: If you have diabetes or kidney issues, avoid combining Aliskiren with Tribenzor, as it can worsen kidney problems, cause your blood pressure to drop too low, and increase potassium levels in your blood dangerously.
• Other Blood Pressure Medications: Using other drugs that lower blood pressure along with Tribenzor might cause your blood pressure to drop too much.
• Steroids: These can decrease the effectiveness of Tribenzor and can lead to imbalances in your body’s electrolytes.
• Alcohol, Barbiturates, Narcotics, or Antidepressants: These substances can enhance the blood pressure-lowering effects of Tribenzor, which might make you feel unusually dizzy.
• Cholestyramine and Colestipol: These drugs can interfere with how your body absorbs hydrochlorothiazide (one of the components of Tribenzor), making it less effective.
• Diabetes Medications: Tribenzor might affect your blood sugar levels, so you might need to change the dosage of your diabetes medications.
• Supplements like Potassium: Since Tribenzor includes a diuretic, taking potassium supplements or using salt substitutes containing potassium could cause your potassium levels to rise too much, which is dangerous.

What Are the Substance Interacts with Tribenzor?

Blood pressure medication Tribenzor, may interact with various substances, affecting how well the medication works or increasing the risk of side effects. Here are some notable interactions:

• Alcohol: Consumption can enhance the blood pressure-lowering effects of Tribenzor, leading to increased dizziness or risk of fainting.
• NSAIDs (Non-Steroidal Anti-Inflammatory Drugs): Medications like ibuprofen and naproxen can reduce the effectiveness of Tribenzor and potentially increase the risk of kidney problems.
• Supplements: Potassium supplements and salt substitutes containing potassium can elevate the risk of high potassium levels when taken with Tribenzor, mainly due to the presence of the ACE inhibitor component.
• Other Blood Pressure Medications: Using Tribenzor with other drugs that lower blood pressure can enhance the effects, potentially causing blood pressure levels to drop too low.
• Lithium: Tribenzor can increase lithium levels in the blood, enhancing its effects and side effects.
• Steroids: Can reduce the effectiveness of Tribenzor in lowering blood pressure.
• Diabetes Medications: Tribenzor can alter the blood sugar-lowering effects of diabetes medications, requiring adjustments in doses.
• Cholestyramine and Colestipol: These cholesterol medications can decrease the absorption and effectiveness of Tribenzor.

[Note: This is not a complete list of Tribenzor, and there could be other drugs that interact with Tribenzor. Make sure to tell your doctor about any prescription, over-the-counter, or herbal products you’re taking.]

What Is the Best Alternative to Tribenzor?

Tribenzor is a combination medication containing olmesartan (an angiotensin II receptor blocker), amlodipine (a calcium channel blocker), and hydrochlorothiazide (a thiazide diuretic). It’s used to treat high blood pressure. Here are some alternatives to blood pressure medication Tribenzor:

Single-component Medications

• Cozaar (losartan)
• Diovan (valsartan)
• Avapro (irbesartan)
• Zestril (lisinopril)
• Altace (ramipril)
• Vasotec (enalapril)
• Norvasc (amlodipine)
• Cardizem (diltiazem)
• Microzide (hydrochlorothiazide)
• Lasix (furosemide)
• Toprol-XL (metoprolol)
• Coreg (carvedilol)

Other Classes of Blood Pressure Medications

• Cardura (doxazosin)
• Tekturna (aliskiren)
• Catapres (clonidine)

Other Combination Medications

• Exforge HCT (valsartan/amlodipine/hydrochlorothiazide)
• Tekturna HCT (aliskiren/hydrochlorothiazide)
• Azor (olmesartan/amlodipine)
• Hyzaar (losartan/hydrochlorothiazide)

[Note: Your doctor will choose the most suitable Tribenzor alternative. Don’t use any of these alternative medications without medical supervision. Taking them on your own may cause serious side effects.]

Tribenzor Discount Coupons & Cost

Tribenzor is a powerful option for controlling high blood pressure, but the high retail prices in the US can be challenging for many patients. US residents can consider purchasing Tribenzor from Canadian pharmacies for more affordable alternatives. Polar Bear Meds is a trusted source renowned for its competitive medication pricing. By using the Tribenzor discount coupon code “WELCOMEPB10” at checkout, customers can avail up to 10% off on their first order. Additionally, our referral program provides extra savings, including a free coupon for future purchases. Secure your Tribenzor supply from Canada and benefit from significant cost savings.

Frequently Asked Questions

Is Tribenzor the same as olmesartan?

No, Tribenzor is not the same as olmesartan. Tribenzor is a combination medication that includes olmesartan, amlodipine, and hydrochlorothiazide. These three components work together to effectively lower high blood pressure.

Can Tribenzor be cut in half?

No, you should not cut Tribenzor tablets in half. The tablet should be swallowed whole without breaking, crushing, or chewing it. This ensures the medication is released and absorbed properly. You can take Tribenzor with or without food. If you are taking colesevelam (Welchol), make sure to take it at least 4 hours after your Tribenzor dose.

Is it better to take Tribenzor at night or in the morning?

Your doctor might recommend taking your first dose of blood pressure medication, Tribenzor, at bedtime, as it can make you dizzy. After the first dose, you can take it at any time of day. Most people prefer taking it in the morning for convenience.

How can I tell if Tribenzor is effective?

To check if Tribenzor is working, regularly measure your blood pressure at home and keep a log of the readings. Share this information with your healthcare provider during appointments to assess how well the medication is managing your blood pressure. Continue taking Tribenzor as prescribed, even if you feel fine, as high blood pressure often has no obvious symptoms but is still damaging to your health.

Should I consider starting Tribenzor if I have recently been diagnosed with high blood pressure?

Tribenzor is usually not the first medication prescribed for newly diagnosed high blood pressure. Starting with a combination of all three drugs in Tribenzor might lower your blood pressure too much, leading to side effects like dizziness. It might be considered if you have tried multiple other blood pressure medications without sufficient results.

Can I use Tribenzor if I have kidney issues?

If you have kidney problems, discuss this with your doctor before starting Tribenzor. While some components of Tribenzor, like ARBs and hydrochlorothiazide, can help slow down kidney damage in early stages, Tribenzor may not be suitable for everyone with kidney conditions. It can worsen kidney issues or affect electrolyte levels. 

Is it safe to take Tribenzor during pregnancy?

You should avoid taking blood pressure medication Tribenzor, during pregnancy. It contains olmesartan, which can cause serious harm to an unborn baby. The safety of other components like amlodipine and hydrochlorothiazide during pregnancy is also not well established. 

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